Contents

Current Pharmaceutical Design, Volume 19 - Number 3

Editorial

Editorial: [Hot Topic: Molecular Chaperones as Drug Targets]

, 19(3): 307 - 308

Hitoshi Nakamoto and Hiroyuki Osada


DOI: 10.2174/1381612811306030307




Hydroximic Acid Derivatives: Pleiotropic Hsp Co-Inducers Restoring Homeostasis and Robustness

, 19(3): 309 - 346

Tim Crul, Noemi Toth, Stefano Piotto, Peter Literati-Nagy, Kalman Tory, Pierre Haldimann, Bernadett Kalmar, Linda Greensmith, Zsolt Torok, Gabor Balogh, Imre Gombos, Federica Campana, Simona Concilio, Ferenc Gallyas, Gabor Nagy, Zoltan Berente, Burcin Gungor, Maria Peter, Attila Glatz, Akos Hunya, Zsuzsanna Literati-Nagy, Laszlo Vigh, Femke Hoogstra-Berends, Andre Heeres, Irma Kuipers, Lizette Loen, Jean-Paul Seerden, Deli Zhang, Roelien A M Meijering, Robert H Henning, Bianca J J M Brundel, Harm H Kampinga, Laszlo Koranyi, Zoltan Szilvassy, Jozsef Mandl, Balazs Sumegi, Mark A Febbraio, Ibolya Horvath, Philip L Hooper and Laszlo Vigh


DOI: 10.2174/1381612811306030309




The Therapeutic Target Hsp90 and Cancer Hallmarks

, 19(3): 347 - 365

Yoshihiko Miyata, Hitoshi Nakamoto and Len Neckers


DOI: 10.2174/1381612811306030347




Hsp90 Inhibitors as Anti-Cancer Agents, from Basic Discoveries to Clinical Development

, 19(3): 366 - 376

Shiro Soga, Shiro Akinaga and Yukimasa Shiotsu


DOI: 10.2174/1381612811306030366




Heat Shock Protein 90 Inhibitors as Broad Spectrum Anti-Infectives

, 19(3): 377 - 386

Ankit K. Rochani, Meetali Singh and Utpal Tatu


DOI: 10.2174/1381612811306030377




Hsp70s and J Proteins of Plasmodium Parasites Infecting Rodents and Primates: Structure, Function, Clinical Relevance, and Drug Targets

, 19(3): 387 - 403

James M. Njunge, Michael H. Ludewig, Aileen Boshoff, Eva-Rachele Pesce and Gregory L. Blatch


DOI: 10.2174/1381612811306030387




Hsp70 Protein Complexes as Drug Targets

, 19(3): 404 - 417

Victoria A. Assimon, Anne T. Gillies, Jennifer N. Rauch and Jason E. Gestwicki


DOI: 10.2174/1381612811306030404




Druggability of Mortalin for Cancer and Neuro-Degenerative Disorders

, 19(3): 418 - 429

Custer C. Deocaris, Wen-Jing Lu, Sunil C. Kaul and Renu Wadhwa


DOI: 10.2174/1381612811306030418




Lysosomal Rerouting of Hsp70 Trafficking as a Potential Immune Activating Tool for Targeting Melanoma

, 19(3): 430 - 440

Kata Juhasz, Roland Thuenauer, Andrea Spachinger, Ern Duda, Ibolya Horvath, Laszlo Vigh, Alois Sonnleitner and Zsolt Balogi


DOI: 10.2174/1381612811306030430




HSP60 as a Drug Target

, 19(3): 441 - 451

Hiroyuki Nakamura and Hidemitsu Minegishi


DOI: 10.2174/1381612811306030441




Chaperonopathies and Chaperonotherapy. Hsp60 as Therapeutic Target in Cancer: Potential Benefits and Risks

, 19(3): 452 - 457

Francesco Cappello, Francesca Angileri, Everly Conway de Macario and Alberto J. L. Macario


DOI: 10.2174/1381612811306030452




S-nitrosation/Denitrosation in Cardiovascular Pathologies: Facts and Concepts for the Rational Design of S-nitrosothiols

, 19(3): 458 - 472

Caroline Gaucher, Ariane Boudier, Fatima Dahboul, Marianne Parent and Pierre Leroy


DOI: 10.2174/1381612811306030458




High-throughput Screening Identifies Small Molecule Inhibitors of Molecular Chaperones

, 19(3): 473 - 492

Yasumitsu Kondoh and Hiroyuki Osada


DOI: 10.2174/1381612811306030473




Superparamagnetic Iron Oxide Nanoparticles (SPIONs): Synthesis and Surface Modification Techniques for use with MRI and Other Biomedical Applications

, 19(3): 493 - 509

Serge Yoffe, Tim Leshuk, Perry Everett and Frank Gu


DOI: 10.2174/1381612811306030493




Intranasal Drug Delivery to the Central Nervous System: Present Status and Future Outlook

, 19(3): 510 - 526

Seyed Khosrow Tayebati, Innocent Ejike Nwankwo and Francesco Amenta


DOI: 10.2174/1381612811306030510




Corrigendum

, 19(3): 527

Paul A. Lapchak


DOI: 10.2174/1381612811306030527




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