Contents

Current Pharmaceutical Design, Volume 19 - Number 18

Editorial(Hot Topic:Targeting the Ubiquitin-Proteasome Pathway - Current Perspectives and Future Directions)

, 19(18): 3173 - 3174

Xinliang Mao


DOI: 10.2174/1381612811319180001




Emerging Role of the Ubiquitin-proteasome System as Drug Targets

, 19(18): 3175 - 3189

Gozde Kar, Ozlem Keskin, Franca Fraternali and Attila Gursoy


DOI: 10.2174/1381612811319180002




Dissecting Bortezomib: Development, Application, Adverse Effects and Future Direction

, 19(18): 3190 - 3200

Biyin Cao, Jie Li and Xinliang Mao


DOI: 10.2174/13816128113199990338




Targeting the Ubiquitin E1 as a Novel Anti-Cancer Strategy

, 19(18): 3201 - 3209

Wei Xu, Julie L. Lukkarila, Sara R. da Silva, Stacey-Lynn Paiva, Patrick T. Gunning and Aaron D. Schimmer


DOI: 10.2174/1381612811319180004




Cdc20: A Potential Novel Therapeutic Target for Cancer Treatment

, 19(18): 3210 - 3214

Zhiwei Wang, Lixin Wan, Jiateng Zhong, Hiroyuki Inuzuka, Pengda Liu, Fazlul H. Sarkar and Wenyi Wei


DOI: 10.2174/1381612811319180005




Cullin-RING Ligases as Attractive Anti-cancer Targets

, 19(18): 3215 - 3225

Yongchao Zhao and Yi Sun


DOI: 10.2174/13816128113199990300




Pharmaceutical Perspectives of HECT-TYPE Ubiquitin Ligase Smurf1

, 19(18): 3226 - 3233

Yu Cao and Lingqiang Zhang


DOI: 10.2174/1381612811319180007




Deubiquitinating Enzymes as Promising Drug Targets for Infectious Diseases

, 19(18): 3234 - 3247

Bindu Nanduri, Akamol E. Suvarnapunya, Malabi Venkatesan and Mariola J. Edelmann


DOI: 10.2174/1381612811319180008




Targeting the Ubiquitin-Mediated Proteasome Degradation of p53 for Cancer Therapy

, 19(18): 3248 - 3262

Tiffany DeVine and Mu-Shui Dai


DOI: 10.2174/1381612811319180009




When Ubiquitin Meets NF-κB: A Trove for Anti-cancer Drug Development

, 19(18): 3263 - 3275

Zhao-Hui Wu and Yuling Shi


DOI: 10.2174/1381612811319180010




Regulation of Skeletal Muscle Plasticity by Glycogen Synthase Kinase-3β: A Potential Target for the Treatment of Muscle Wasting

, 19(18): 3276 - 3298

Koen J.P. Verhees, Nicholas A.M. Pansters, Annemie M.W.J. Schols and Ramon C.J. Langen


DOI: 10.2174/1381612811319180011




Proteasome Inhibition in Transplantation-Focusing on the Experience with Bortezomib

, 19(18): 3299 - 3304

Yong Liang and Haiyan Liu


DOI: 10.2174/13816128113199990308




The Ubiquitin Proteasome System as a Potential Target for the Treatment of Neurodegenerative Diseases

, 19(18): 3305 - 3314

Zheng Ying, Hongfeng Wang and Guanghui Wang


DOI: 10.2174/1381612811319180013




Comprehensive Profiling of Protein Ubiquitination for Drug Discovery

, 19(18): 3315 - 3328

Guoqiang Xu and Samie R. Jaffrey


DOI: 10.2174/13816128113199990305




An Update of Radiolabeled Bombesin Analogs for Gastrin-Releasing Peptide Receptor Targeting

, 19(18): 3329 - 3341

Zilin Yu, Hildo J. K. Ananias, Giuseppe Carlucci, Hilde D. Hoving, Wijnand Helfrich, Rudi A.J.O. Dierckx, Fan Wang, Igle J. de Jong and Philip H. Elsinga


DOI: 10.2174/1381612811319180015




Ultrasound-Based Multimodal Molecular Imaging and Functional Ultrasound Contrast Agents

, 19(18): 3342 - 3351

Yan Lin, Zhi-Yi Chen and Feng Yang


DOI: 10.2174/1381612811319180016




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