Contents

Current Pharmaceutical Design, Volume 19 - Number 10

Editorial

Editorial (Hot Topic: The Development of Novel Inhibitors for the Treatment of HIV Infection)

, 19(10): 1765 - 1766

Jian Jun Tan and Cun Xin Wang


DOI: 10.2174/1381612811319100001




Anti-HIV Drug Development: Structural Features and Limitations of Present Day Drugs and Future Challenges in the Successful HIV/AIDS Treatment

, 19(10): 1767 - 1783

Garima Kumari and Ramendra K. Singh


DOI: 10.2174/13816128113199990295




Inhibitors of HIV-1 Entry

, 19(10): 1784 - 1799

Ewa D. Micewicz and Piotr Ruchala


DOI: 10.2174/1381612811319100003




Synthesized Peptide Inhibitors of HIV-1 gp41-dependent Membrane Fusion

, 19(10): 1800 - 1809

Yuxian He


DOI: 10.2174/1381612811319100004




The Current Status and Challenges in the Development of Fusion Inhibitors as Therapeutics for HIV-1 Infection

, 19(10): 1810 - 1817

Jian Jun Tan, Xue Ting Ma, Chang Liu, Xiao Yi Zhang and Cun Xin Wang


DOI: 10.2174/1381612811319100005




Discovery of Small Molecule Fusion Inhibitors Targeting HIV-1 gp41

, 19(10): 1818 - 1826

Guangyan Zhou and Shidong Chu


DOI: 10.2174/1381612811319100006




Development of Small Molecule HIV-1 Fusion Inhibitors: Linking Biology to Chemistry

, 19(10): 1827 - 1834

Fusako Miyamoto and Eiichi N. Kodama


DOI: 10.2174/1381612811319100007




Quinoline-based HIV Integrase Inhibitors

, 19(10): 1835 - 1849

Robert Musiol


DOI: 10.2174/1381612811319100008




Molecular Aspects of the RT/drug Interactions. Perspective of Dual Inhibitors

, 19(10): 1850 - 1859

Simona Distinto, Elias Maccioni, Rita Meleddu, Angela Corona, Stefano Alcaro and Enzo Tramontano


DOI: 10.2174/1381612811319100009




Blocking HIV-1 Replication by Targeting the Tat-Hijacked Transcriptional Machinery

, 19(10): 1860 - 1879

Serena Massari, Stefano Sabatini and Oriana Tabarrini


DOI: 10.2174/1381612811319100010




From the Chemistry of Epoxy-Sugar Nucleosides to the Discovery of Anti-HIV Agent 4'-ethynylstavudine-Festinavir

, 19(10): 1880 - 1897

Kazuhiro Haraguchi, Shingo Takeda, Yutaka Kubota, Hiroki Kumamoto, Hiromichi Tanaka, Takayuki Hamasaki, Masanori Baba, Elijah Paintsil and Yung-Chi Cheng


DOI: 10.2174/1381612811319100011




Pharmacological Properties of Glutamatergic Drugs Targeting NMDA Receptors and their Application in Major Depression

, 19(10): 1898 - 1922

Gianluca Serafini, Maurizio Pompili, Marco Innamorati, Yogesh Dwivedi, Goutam Brahmachari and Paolo Girardi


DOI: 10.2174/13816128113199990293




Design of Combretastatin A-4 Analogs as Tubulin Targeted Vascular Disrupting Agent with Special Emphasis on Their Cis-Restricted Isomers

, 19(10): 1923 - 1955

Harish Rajak, Pramod Kumar Dewangan, Vijay Patel, Deepak Kumar Jain, Avineesh Singh, Ravichandran Veerasamy, Prabodh Chander Sharma and Anshuman Dixit


DOI: 10.2174/1381612811319100013




Long-term Etanercept Therapy Favors Weight Gain and Ameliorates Cachexia in Rheumatoid Arthritis Patients: Roles of Gut Hormones and Leptin

, 19(10): 1956 - 1964

Chih-Yen Chen, Chang-Youh Tsai, Pui-Ching Lee and Shou-Dong Lee


DOI: 10.2174/1381612811319100014




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