Contents

Current Pharmaceutical Design, Volume 18 - Number 7

Editorial [Hot Topic: Sigma Receptor Research: Progress Towards Diagnostic and Therapeutic Uses of Sigma Ligands (Executive Guest Editor: Carmen Abate )]

, 18(7): 861 - 862

Carmen Abate


DOI: 10.2174/138161212799436502




Pharmacology of Sigma (σ) Receptor Ligands from a Behavioral Perspective

, 18(7): 863 - 874

Grazyna Skuza


DOI: 10.2174/138161212799436458




Sigma-1 Receptor Agonists as Therapeutic Drugs for Cognitive Impairment in Neuropsychiatric Diseases

, 18(7): 875 - 883

Tomihisa Niitsu, Masaomi Iyo and Kenji Hashimoto


DOI: 10.2174/138161212799436476




The Therapeutic Potential of Sigma (σ) Receptors for the Treatment of Central Nervous System Diseases: Evaluation of the Evidence

, 18(7): 884 - 901

Samuel D. Banister and Michael Kassiou


DOI: 10.2174/138161212799436539




Sigma-1 Receptors: Potential Targets for the Treatment of Substance Abuse

, 18(7): 902 - 919

Matthew J. Robson, Bahar Noorbakhsh, Michael J. Seminerio and Rae R. Matsumoto


DOI: 10.2174/138161212799436601




The Ligand Binding Region of the Sigma-1 Receptor: Studies Utilizing Photoaffinity Probes, Sphingosine and N-Alkylamines

, 18(7): 920 - 929

Arnold E. Ruoho, Uyen B. Chu, Subramaniam Ramachandran, Dominique Fontanilla, Timur Mavlyutov and Abdol R. Hajipour


DOI: 10.2174/138161212799436584




Pharmacophore Models and Development of Spirocyclic Ligands for σ1 Receptors

, 18(7): 930 - 937

Bernhard Wunsch


DOI: 10.2174/138161212799436548




Classes of Sigma2 (σ2) Receptor Ligands: Structure Affinity Relationship (SAfiR) Studies and Antiproliferative Activity

, 18(7): 938 - 949

Carmen Abate, Roberto Perrone and Francesco Berardi


DOI: 10.2174/138161212799436485




Editorial [Hot Topic: Inhibition of the Renin-Angiotensin-Aldosterone System: How to Obtain This (Executive Guest Editors: Aldo Pende and Fabrizio Montecucco )]

, 18(7): 950 - 951

Fabrizio Montecucco


DOI: 10.2174/138161212799436494




Combinations of Renin-Angiotensin-Aldosterone System Antagonists:True Advantages?

, 18(7): 952 - 957

Franco Veglio, Elisabetta Puglisi, Alberto Milan and Paolo Mulatero


DOI: 10.2174/138161212799436566




Renin-Angiotensin-Aldosterone System Antagonists and the Prevention of Type 2 Diabetes Mellitus

, 18(7): 958 - 962

Nikolaus Marx


DOI: 10.2174/138161212799436557




Role of Renin-Angiotensin System in Inflammation, Immunity and Aging

, 18(7): 963 - 970

Luciano S.A. Capettini, Fabrizio Montecucco, Francois Mach, Nikos Stergiopulos, Robson A.S. Santos and Rafaela F. da Silva


DOI: 10.2174/138161212799436593




RAAS Inhibition and Renal Protection

, 18(7): 971 - 980

Leoncini Giovanna, Viazzi Francesca and Pontremoli Roberto


DOI: 10.2174/138161212799436520




Role of the Renin-Angiotensin-Aldosterone System in the Pathogenesis of Atherosclerosis

, 18(7): 981 - 1004

Alessandro Durante, Giovanni Peretto, Alessandra Laricchia, Francesco Ancona, Marco Spartera, Antonio Mangieri and Domenico Cianflone


DOI: 10.2174/138161212799436467




Vaccination Against High Blood Pressure

, 18(7): 1005 - 1010

Duncan J. Campbell


DOI: 10.2174/138161212799436511




Renin-Angiotensin Antagonists: Therapeutic Effects Beyond Blood Pressure Control?

, 18(7): 1011 - 1020

Franco Dallegri


DOI: 10.2174/138161212799436575




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