Contents

Current Pharmaceutical Design, Volume 18 - Number 27

Editorial

Editorial: [Hot Topic: TGF-β1 in Pre-Malignant and Malignant Liver Disease]

, 18(27): 4071

Gianluigi Giannelli


DOI: 10.2174/138161212802430512




Context-dependent Action of Transforming Growth Factor β Family Members on Normal and Cancer Stem Cells

, 18(27): 4072 - 4086

Laia Caja, Kaoru Kahata and Aristidis Moustakas


DOI: 10.2174/138161212802430459




Deregulated Bone Morphogenetic Protein Receptor Signaling Underlies Fibrodysplasia Ossificans Progressiva

, 18(27): 4087 - 4092

David J.J. de Gorter, Vishant Jankipersadsing and Peter ten Dijke


DOI: 10.2174/138161212802430495




Cellular Players in Lung Fibrosis

, 18(27): 4093 - 4102

Annemarie N. Lekkerkerker, Jamil Aarbiou, Thomas van Es and Richard A.J. Janssen


DOI: 10.2174/138161212802430396




TGFβ Signaling in Liver Regeneration

, 18(27): 4103 - 4113

Sofia Karkampouna, Peter ten Dijke, Steven Dooley and Marianna Kruithof-de Julio


DOI: 10.2174/138161212802430521




BMPS and Liver: More Questions than Answers

, 18(27): 4114 - 4125

Blanca Herrera, Aranzazu Sanchez and Isabel Fabregat


DOI: 10.2174/138161212802430503




TGF-Beta: a Master Switch in Tumor Immunity

, 18(27): 4126 - 4134

Margherita Gigante, Loreto Gesualdo and Elena Ranieri


DOI: 10.2174/138161212802430378




TGF-β in Epithelial to Mesenchymal Transition and Metastasis of Liver Carcinoma

, 18(27): 4135 - 4147

Patrick Reichl, Christine Haider, Markus Grubinger and Wolfgang Mikulits


DOI: 10.2174/138161212802430477




The TGF-β Signaling Pathway as a Pharmacological Target in a Hepatocellular Carcinoma

, 18(27): 4148 - 4154

Antonio Mazzocca, Salvatore Antonaci and Gianluigi Giannelli


DOI: 10.2174/138161212802430431




TGF-Beta Inihibitor-loaded Polyelectrolyte Multilayers Capsules for Sustained Targeting of Hepatocarcinoma Cells

, 18(27): 4155 - 4164

Viviana Vergaro, Francesca Baldassarre, Flavia De Santis, Giuseppe Ciccarella, Gianluigi Giannelli and Stefano Leporatti


DOI: 10.2174/138161212802430404




The Development of HEPT-Type HIV Non-Nucleoside Reverse Transcriptase Inhibitors and Its Implications for DABO Family

, 18(27): 4165 - 4186

Wenmin Chen, Peng Zhan, Jingde Wu, Zhenyu Li and Xinyong Liu


DOI: 10.2174/138161212802430440




Removal of the Tag from His-tagged ILYd4, a Human CD59 Inhibitor, Significantly Improves its Physical Properties and its Activity

, 18(27): 4187 - 4196

Lin Wu, Sanbao Su, Fengming Liu, Tao Xu, Xiaoxiao Wang, Yan Huang, Xinlu Sun, Xiaowen Ge, Ting Chen, Huixia Liu, Chun Wang, Michael Chorev, Ting Xu and Xuebin Qin


DOI: 10.2174/138161212802430486




Structure and Ligand-based Design of P-glycoprotein Inhibitors: A Historical Perspective

, 18(27): 4197 - 4214

Andreia Palmeira, Emilia Sousa, M. Helena Vasconcelos, Madalena Pinto and Miguel X. Fernandes


DOI: 10.2174/138161212802430530




Preclinical Safety and Pharmacokinetic Profile of 3K3A-APC, a Novel, Modified Activated Protein C for Ischemic Stroke

, 18(27): 4215 - 4222

Patricia D. Williams, Berislav V. Zlokovic, John H. Griffin, Kent E. Pryor and Thomas P. Davis


DOI: 10.2174/138161212802430413




New Therapeutic Strategies for Cancer and Neurodegeneration Emerging from Yeast Cell-based Systems

, 18(27): 4223 - 4235

Clara Pereira, Mariana Leao, Joana Soares, Claudia Bessa and Lucilia Saraiva


DOI: 10.2174/138161212802430422




A Computational Study of the Oligosaccharide Binding Sites in the Lectin-Like Domain of Tumor Necrosis Factor and the TNF-derived TIP Peptide

, 18(27): 4236 - 4243

Alexander Dulebo, Rudiger Ettrich, Rudolf Lucas and David Kaftan


DOI: 10.2174/138161212802430549




Target-based Anti-angiogenic Therapy in Breast Cancer

, 18(27): 4244 - 4257

Markus Wehland, Johann Bauer, Manfred Infanger and Daniela Grimm


DOI: 10.2174/138161212802430468




The Effect of First-in-Class Small Molecule RhoA Inhibitor, HL07, on the Phenylephrine-induced Artery Contraction

, 18(27): 4258 - 4264

Yan Zhang, Jing Deng, Sheng Ma, Lin Xue, Jin Zhu, Wei-liang Zhu, Hua-liang Jiang, Jian Li and Li-yan Miao


DOI: 10.2174/138161212802430387




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