Contents

Current Pharmaceutical Design, Volume 18 - Number 2

Editorial [Hot Topic: From Structural Plasticity to Functional Diversity of 7TMRs: Biased Agonism and Beyond (Executive Guest Editor: Christodoulos S. Flordellis)]

, 18(2): 119 - 120

Christodoulos S. Flordellis


DOI: 10.2174/138161212799040538




GRK2 at the Control Shaft of Cellular Metabolism

, 18(2): 121 - 127

Michele Ciccarelli, Ersilia Cipolletta and Guido Iaccarino


DOI: 10.2174/138161212799040493




Probing Heterotrimeric G Protein Activation: Applications to Biased Ligands

, 18(2): 128 - 144

Colette Denis, Aude Sauliere, Segolene Galandrin, Jean-Michel Senard and Celine Gales


DOI: 10.2174/138161212799040466




The Plasticity of the 7TMR Signaling Machinery and the Search for Pharmacological Selectivity

, 18(2): 145 - 160

Christodoulos S. Flordellis


DOI: 10.2174/138161212799040556




The Multiple Layers of Signaling Selectivity at Protease-Activated Receptors

, 18(2): 161 - 174

Iason Kyriazis, John Ellul, Paraskevi Katsakiori, George Panayiotakopoulos and Christodoulos Flordellis


DOI: 10.2174/138161212799040484




The G-protein Coupled Receptor Family: Actors with Many Faces

, 18(2): 175 - 185

George Liapakis, Arnau Cordomi and Leonardo Pardo


DOI: 10.2174/138161212799040529




GRK2 Inhibition in Heart Failure: Something Old, Something New

, 18(2): 186 - 191

Anastasios Lymperopoulos, Giuseppe Rengo and Walter J. Koch


DOI: 10.2174/138161212799040510




Beta-arrestin Biased Agonism/Antagonism at Cardiovascular Seven Transmembrane-spanning Receptors

, 18(2): 192 - 198

Anastasios Lymperopoulos


DOI: 10.2174/138161212799040475




Herve Paris (1953 – 2010) Tribute by Chris S. Flordellis

, 18(2): 199

Christodoulos S. Flordellis


DOI: 10.2174/138161212799040565




Current Opinions and Perspectives on the Role of Immune System in the Pathogenesis of Parkinson's Disease

, 18(2): 200 - 208

Maria Antonietta Panaro and Antonia Cianciulli


DOI: 10.2174/138161212799040574




Current Treatment Strategies for Multiple Sclerosis - Efficacy Versus Neurological Adverse Effects

, 18(2): 209 - 219

Martin S. Weber, Til Menge, Klaus Lehmann-Horn, Helena C. Kronsbein, Uwe Zettl, Johann Sellner, Bernhard Hemmer and Olaf Stuve


DOI: 10.2174/138161212799040501




Enkephalin Degrading Enzymes: Metalloproteases with High Potential for Drug Development

, 18(2): 220 - 230

Tejinder Pal Khaket, Jasbir Singh, Pooja Attri and Suman Dhanda


DOI: 10.2174/138161212799040547




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