Contents

Current Pharmaceutical Design, Volume 18 - Number 19

Editorial [Hot Topic: Targeting Molecular Pathways in Human Malignancy: Current Status and Future Development (Executive Guest Editor: Gabriella Ferrandina)]

, 18(19): 2671

Gabriella Ferrandina


DOI: 10.2174/138161212800626256




Targeting the EGFR-family for Therapy: Biological Challenges and Clinical Perspective

, 18(19): 2672 - 2679

Rachana Patel and Hing Y. Leung


DOI: 10.2174/138161212800626148




Anti-VEGF Strategies – from Antibodies to Tyrosine Kinase Inhibitors: Background and Clinical Development in Human Cancer

, 18(19): 2680 - 2701

Grzegorz Korpanty and Elizabeth Smyth


DOI: 10.2174/138161212800626166




Novel VEGF-independent Strategies Targeting Tumor Vasculature: Clinical Aspects

, 18(19): 2702 - 2712

Marco Petrillo, Maddalena Borriello, Gilda Fuoco, Francesco Legge, Vito Iannone and Gabriella Ferrandina


DOI: 10.2174/138161212800626184




Moving Beyond VEGF for Anti-angiogenesis Strategies in Gynecologic Cancer

, 18(19): 2713 - 2719

Duangmani Thanapprapasr, Wei Hu, Anil K Sood and Robert L Coleman


DOI: 10.2174/138161212800626201




The Endothelin Axis as Therapeutic Target in Human Malignancies: Present and Future

, 18(19): 2720 - 2733

Anna Bagnato


DOI: 10.2174/138161212800626157




Estrogen Receptor Beta in Cancer: an Attractive Target for Therapy

, 18(19): 2734 - 2757

Daniela Gallo, Ilaria De Stefano, Maria Grazia Prisco, Giovanni Scambia and Gabriella Ferrandina


DOI: 10.2174/138161212800626139




The Role of FLT3 Kinase as an AML Therapy Target

, 18(19): 2758 - 2765

Michal Beffinger and Anna Skwarska


DOI: 10.2174/138161212800626247




Targeting mTOR Pathways in Human Malignancies

, 18(19): 2766 - 2777

Angelica Fasolo and Cristiana Sessa


DOI: 10.2174/138161212800626210




Tubulins as Therapeutic Targets in Cancer: from Bench to Bedside

, 18(19): 2778 - 2792

Christos D. Katsetos and Pavel Draber


DOI: 10.2174/138161212800626193




Novel Drugs Targeting Microtubules: the Role of Epothilones

, 18(19): 2793 - 2803

Gabriella Ferrandina, Marisa Mariani, Mirko Andreoli, Shohreh Shahabi, Giovanni Scambia and Cristiano Ferlini


DOI: 10.2174/138161212800626238




Approaches for Developing Novel Microtubule Targeting Agents (MTAs) for Therapeutic Exploitation

, 18(19): 2804 - 2810

Aswini Krishnan, James Wilson and Hing Y. Leung


DOI: 10.2174/138161212800626111




Molecular Targets of Gemcitabine Action: Rationale for Development of Novel Drugs and Drug Combinations

, 18(19): 2811 - 2829

Maha Elnaggar, Elisa Giovannetti and Godefridus J. Peters


DOI: 10.2174/138161212800626175




Chemoradiotherapy of Human Tumors: Novel Approaches from Nanomedicine

, 18(19): 2830 - 2837

Michael Edward Werner, Michael Bonner Foote and Andrew Zhuang Wang


DOI: 10.2174/138161212800626229




Cancer Stem Cells and Novel Targets for Antitumor Strategies

, 18(19): 2838 - 2849

Gerald J. Prud’homme


DOI: 10.2174/138161212800626120




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