Contents

Current Pharmaceutical Design, Volume 18 - Number 14

Editorial [Hot Topic: The Impact of the G-Quadruplex Conformation in the Development of Novel Therapeutic and Diagnostic Agents Executive (Guest Editor: Stefano Alcaro)]

, 18(14): 1865 - 1866

Stefano Alcaro


DOI: 10.2174/138161212799958413




Cell Cycle Regulation of G-Quadruplex DNA Structures at Telomeres

, 18(14): 1867 - 1872

Stefan A. Juranek and Katrin Paeschke


DOI: 10.2174/138161212799958404




The Polymorphisms of DNA G-Quadruplex Investigated by Docking Experiments with Telomestatin Enantiomers

, 18(14): 1873 - 1879

Stefano Alcaro, Giosue Costa, Simona Distinto, Federica Moraca, Francesco Ortuso, Lucia Parrotta and Anna Artese


DOI: 10.2174/138161212799958495




State-of-the-Art Methodologies for the Discovery and Characterization of DNA G-Quadruplex Binders

, 18(14): 1880 - 1899

Bruno Pagano, Sandro Cosconati, Valerie Gabelica, Luigi Petraccone, Stefano De Tito, Luciana Marinelli, Valeria La Pietra, Francesco Saverio di Leva, Ilaria Lauri, Roberta Trotta, Ettore Novellino, Concetta Giancola and Antonio Randazzo


DOI: 10.2174/138161212799958332




Experimental Methods for Studying the Interactions between G-Quadruplex Structures and Ligands

, 18(14): 1900 - 1916

Joaquim Jaumot and Raimundo Gargallo


DOI: 10.2174/138161212799958486




Recent Developments in the Chemistry and Biology of G-Quadruplexes with Reference to the DNA Groove Binders

, 18(14): 1917 - 1933

Akash K. Jain and Santanu Bhattacharya


DOI: 10.2174/138161212799958396




Heterocyclic Dications as a New Class of Telomeric G-Quadruplex Targeting Agents

, 18(14): 1934 - 1947

Rupesh Nanjunda, Caterina Musetti, Arvind Kumar, Mohamed A. Ismail, Abdelbasset A. Farahat, Siming Wang, Claudia Sissi, Manlio Palumbo, David W. Boykin and W. David Wilson


DOI: 10.2174/138161212799958422




G-Quadruplex Binding Ligands: from Naturally Occurring to Rationally Designed Molecules

, 18(14): 1948 - 1972

Tuong Vy Thi Le, Sujin Han, Junghyun Chae and Hyun-Ju Park


DOI: 10.2174/138161212799958431




Searching Drug-Like Anti-cancer Compound(s) Based on G-Quadruplex Ligands

, 18(14): 1973 - 1983

Qian Li, Jun-Feng Xiang, Hong Zhang and Ya-Lin Tang


DOI: 10.2174/138161212799958369




Targeting DNA G-Quadruplex Structures with Peptide Nucleic Acids

, 18(14): 1984 - 1991

Igor G. Panyutin, Mykola I. Onyshchenko, Ethan A. Englund, Daniel H. Appella and Ronald D. Neumann


DOI: 10.2174/138161212799958440




Screening of a Chemical Library by HT-G4-FID for Discovery of Selective G-quadruplex Binders

, 18(14): 1992 - 2001

Eric Largy, Nicolas Saettel, Florian Hamon, Sylvie Dubruille and Marie-Paule Teulade-Fichou


DOI: 10.2174/138161212799958350




Structure Conversion and Structure Separation of G-Quadruplexes Investigated by Carbazole Derivatives

, 18(14): 2002 - 2013

Ta-Chau Chang, Jen-Fei Chu, Yu-Lin Tsai and Zi-Fu Wang


DOI: 10.2174/138161212799958503




G-quadruplex DNA Aptamers and their Ligands: Structure, Function and Application

, 18(14): 2014 - 2026

W. O. Tucker, K. T. Shum and J. A. Tanner


DOI: 10.2174/138161212799958477




Folding Versus Charge: Understanding Selective Target Recognition by the Thrombin Aptamers

, 18(14): 2027 - 2035

Giuseppe Marson, Manlio Palumbo and Claudia Sissi


DOI: 10.2174/138161212799958323




Thrombin Binding Aptamer, More than a Simple Aptamer: Chemically Modified Derivatives and Biomedical Applications

, 18(14): 2036 - 2047

Anna Avino, Carme Fabrega, Maria Tintore and Ramon Eritja


DOI: 10.2174/138161212799958387




G-Quadruplex Based Probes for Visual Detection and Sensing

, 18(14): 2048 - 2057

J. L. Neo, K. Kamaladasan and M. Uttamchandani


DOI: 10.2174/138161212799958341




Luminescent G-quadruplex Probes

, 18(14): 2058 - 2075

Dik-Lung Ma, Daniel Shiu-Hin Chan, Hui Yang, Hong-Zhang He and Chung-Hang Leung


DOI: 10.2174/138161212799958314




G-Quadruplex as Signal Transducer for Biorecognition Events

, 18(14): 2076 - 2095

Lei Lv, Zhijun Guo, Jiahai Wang and Erkang Wang


DOI: 10.2174/138161212799958459




Human Telomere RNA: A Potential Target for Ligand Recognition

, 18(14): 2096 - 2101

Yan Xu


DOI: 10.2174/138161212799958378




RNA G-Quadruplexes: G-quadruplexes with “U” Turns

, 18(14): 2102 - 2111

Tani Agarwal, Gopal Jayaraj, Satya Prakash Pandey, Prachi Agarwala and Souvik Maiti


DOI: 10.2174/138161212799958468




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