Contents

Current Pharmaceutical Design, Volume 14 - Number 34

Editorial [Hot Topic: Delivery, Intracellular Trafficking, and Biological Effectiveness of Oligonucleotide-Based Therapeutics Executive Editor: A. Mescalchin and G. Sczakiel]

, 14(34): 3601 - 3602

Alessandra Mescalchin and Georg Sczakiel


DOI: 10.2174/138161208786898824




Cellular Delivery In Vivo of siRNA-Based Therapeutics

, 14(34): 3603 - 3619

A. Aigner


DOI: 10.2174/138161208786898815




Targeting the Lung Using siRNA and Antisense Based Oligonucleotides

, 14(34): 3620 - 3627

Sterghios A. Moschos, Karen Spinks, Andrew E. Williams and Mark A. Lindsay


DOI: 10.2174/138161208786898851




Protein Transduction Revisited: Novel Insights Into the Mechanism Underlying Intracellular Delivery of Proteins

, 14(34): 3628 - 3636

Frank Edenhofer


DOI: 10.2174/138161208786898833




Peptide-Mediated Cellular Delivery of Oligonucleotide-Based Therapeutics In Vitro: Quantitative Evaluation of Overall Efficacy Employing Easy to Handle Reporter Systems

, 14(34): 3637 - 3655

S. D. Laufer and T. Restle


DOI: 10.2174/138161208786898806




Peptide-Based Nanoparticle for Ex Vivo and In Vivo Dug Delivery

, 14(34): 3656 - 3665

Laurence Crombez, May Catherine Morris, Sebastien Deshayes, Frederic Heitz and Gilles Divita


DOI: 10.2174/138161208786898842




Phosphorothioate-Stimulated Cellular Uptake of siRNA: A Cell Culture Model for Mechanistic Studies

, 14(34): 3666 - 3673

A. Detzer, M. Overhoff, A. Mescalchin, M. Rompf and G. Sczakiel


DOI: 10.2174/138161208786898770




siRNA Modifications and Sub-Cellular Localization: A Question of Intracellular Transport?

, 14(34): 3674 - 3685

T. Ohrt and P. Schwille


DOI: 10.2174/138161208786898798




Delivery of siRNA to the Target Cell Cytoplasm: Photochemical Internalization Facilitates Endosomal Escape and Improves Silencing Efficiency, In Vitro and In Vivo

, 14(34): 3686 - 3697

S. Oliveira, A. Hogset and G. Storm


DOI: 10.2174/138161208786898789




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