Contents

Current Pharmaceutical Design, Volume 12 - Number 27

Editorial [Hot Topic: Phosphodiesterase 5 Inhibitors: Pharmacology and Therapeutic Perspectives (Executive Editor: Giuseppe Barbaro)]

, 12(27): 3437

Giuseppe Barbaro


DOI: 10.2174/138161206778343037




Expression, Distribution and Regulation of Phosphodiesterase 5

, 12(27): 3439 - 3457

Ching-Shwun Lin, Guiting Lin, Zhong-Cheng Xin and Tom F. Lue


DOI: 10.2174/138161206778343064




Phosphodiesterase 5 Inhibitors - Drug Design and Differentiation Based on Selectivity, Pharmacokinetic and Efficacy Profiles

, 12(27): 3459 - 3465

Claudiu T. Supuran, Antonio Mastrolorenzo, Giuseppe Barbaro and Andrea Scozzafava


DOI: 10.2174/138161206778343118




Phosphodiesterase 5 Inhibitors in the Treatment of Erectile Dysfunction

, 12(27): 3467 - 3484

Antonio Aversa, Roberto Bruzziches, Marcello Pili and Giovanni Spera


DOI: 10.2174/138161206778343046




Cardiovascular Effects of Phosphodiesterase 5 Inhibitors

, 12(27): 3485 - 3494

Thorsten Reffelmann and Robert A. Kloner


DOI: 10.2174/138161206778343073




Editorial [Hot Topic: New Insights and Strategies in Treating Inflammation-Related Diseases (Executive Editor: Tz-Chong Chou)]

, 12(27): 3495

Tz-Chong Chou


DOI: 10.2174/138161206778343055




Signal Transduction Pathways of Inflammatory Gene Expressions and Therapeutic Implications

, 12(27): 3497 - 3508

Ching-Chow Chen


DOI: 10.2174/138161206778343028




Anti-Inflammatory Drugs in the Treatment of Neurodegenerative Diseases: Current State

, 12(27): 3509 - 3519

Yossi Gilgun-Sherki, Eldad Melamed and Daniel Offen


DOI: 10.2174/138161206778343091




Dual Effects of Antioxidants in Neurodegeneration: Direct Neuroprotection against Oxidative Stress and Indirect Protection via Suppression of Gliamediated Inflammation

, 12(27): 3521 - 3533

Jia-Yi Wang, Li- Li Wen, Ya-Ni Huang, Yen-Tsun Chen and Min-Chi Ku


DOI: 10.2174/138161206778343109




Possible Therapies of Septic Shock: Based on Animal Studies and Clinical Trials

, 12(27): 3535 - 3541

C. C. Wu


DOI: 10.2174/138161206778343019




Therapeutic Use of Nitric Oxide Scavengers in Shock and Sepsis

, 12(27): 3543 - 3549

Brian G. Harbrecht


DOI: 10.2174/138161206778343000




Role of Nitric Oxide and Reactive Oxygen Species in Arthritis

, 12(27): 3551 - 3570

Salvatore Cuzzocrea


DOI: 10.2174/138161206778343082




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