Contents

Current Pharmaceutical Design, Volume 12 - Number 15

Editorial [Hot Topic: HIV-1 Reverse Transcriptase Inhibitors: Drug Resistance and Drug Development (Executive Editors: Nicolas Sluis-Cremer and Ted Ross)]

, 12(15): 1809 - 1810

Nicolas Sluis-Cremer and Ted Ross


DOI: 10.2174/138161206776873635




Insertions and Deletions in HIV-1 Reverse Transcriptase: Consequences for Drug Resistance and Viral Fitness

, 12(15): 1811 - 1825

Luis Menendez-Arias, Tania Matamoros and Clara E. Cases-Gonzalez


DOI: 10.2174/138161206776873608




The Influence of Natural Substrates and Inhibitors on the Nucleotide- Dependent Excision Activity of HIV-1 Reverse Transcriptase in the Infected Cell

, 12(15): 1827 - 1841

Anthony J. Smith and Walter A. Scott


DOI: 10.2174/138161206776873572




Assault on Resistance: The Use of Computational Chemistry in the Development of Anti-HIV Drugs

, 12(15): 1843 - 1856

Marilyn B.K. Smith, Richard H. Smith, Jr. and William L. Jorgensen


DOI: 10.2174/138161206776873581




Developing Novel Nonnucleoside HIV-1 Reverse Transcriptase Inhibitors: Beyond the Butterfly

, 12(15): 1857 - 1865

Karen S. Anderson and Aravind Basavapathruni


DOI: 10.2174/138161206776873617




Effects of Nucleotides and Nucleotide Analogue Inhibitors of HIV-1 Reverse Transcriptase in a Ratchet Model of Polymerase Translocation

, 12(15): 1867 - 1877

Matthias Gotte


DOI: 10.2174/138161206776873626




Dimerization of Human Immunodeficiency Virus Type 1 Reverse Transcriptase as an Antiviral Target

, 12(15): 1879 - 1894

S. Srivastava, N. Sluis-Cremer and G. Tachedjian


DOI: 10.2174/138161206776873590




TSAO Derivatives, Inhibitors of HIV-1 Reverse Transcriptase Dimerization: Recent Progress

, 12(15): 1895 - 1907

M. J. Camarasa, S. Velazquez, A. San-Felix, M. J. Perez-Perez, M. C. Bonache and S. De Castro


DOI: 10.2174/138161206776873563




Recent Progress in the Design of Small Molecule Inhibitors of HIV RNase H

, 12(15): 1909 - 1922

Klaus Klumpp and Tara Mirzadegan


DOI: 10.2174/138161206776873653




Natural and Synthetic Retinoids in Prostate Cancer

, 12(15): 1923 - 1929

D. Pasquali, V. Rossi, G. Bellastella, A. Bellastella and A. A. Sinisi


DOI: 10.2174/138161206776873554




Gq protein-Coupled Receptors as Targets for Anesthetics

, 12(15): 1931 - 1937

Kouichiro Minami and Yasuhito Uezono


DOI: 10.2174/138161206776873644




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