Contents

Current Pharmaceutical Design, Volume 12 - Number 14

Editorial [Hot Topic: G Protein-Coupled Receptor Drug Targets (Executive Editors: P.M. Sexton and A. Christopoulos)]

, 12(14): 1681 - 1682

Patrick M. Sexton and Arthur Christopoulos


DOI: 10.2174/138161206776873699




Mechanisms of ERK1/2 Regulation by Seven-Transmembrane-Domain Receptors

, 12(14): 1683 - 1702

Tim D. Werry, Arthur Christopoulos and Patrick M. Sexton


DOI: 10.2174/138161206776873725




G Proteins in Drug Screening: From Analysis of Receptor-G Protein Specificity to Manipulation of GPCR-Mediated Signalling Pathways

, 12(14): 1703 - 1715

Evi Kostenis


DOI: 10.2174/138161206776873734




Integrative Functional Assays, Chemical Genomics and High Throughput Screening: Harnessing Signal Transduction Pathways to a Common HTS Readout

, 12(14): 1717 - 1729

Ethan S. Burstein, Fabrice Piu, Jian-Nong Ma, Jacques T. Weissman, Erika A. Currier, Norman R. Nash, David M. Weiner, Tracy A. Spalding, Hans H. Schiffer, Andria L. Del Tredici and Mark R. Brann


DOI: 10.2174/138161206776873662




Glucagon and Glucagon-Like Peptide Receptors as Drug Targets

, 12(14): 1731 - 1750

J. L. Estall and D. J. Drucker


DOI: 10.2174/138161206776873671




Cannabinoid Receptors as Therapeutic Targets

, 12(14): 1751 - 1769

Alexandros Makriyannis, Spyros P. Nikas, Ganesh A. Thakur and Spiro Pavlopoulos


DOI: 10.2174/138161206776873743




A Role for Information Collection, Management, and Integration in Structure-Function Studies of G-Protein Coupled Receptors

, 12(14): 1771 - 1783

Jonathan A. Javitch and Lei Shi


DOI: 10.2174/138161206776873707




Screening the Receptorome Yields Validated Molecular Targets for Drug Discovery

, 12(14): 1785 - 1795

Wesley K. Kroeze and Bryan L. Roth


DOI: 10.2174/138161206776873680




Co-Ordinated Covalent Modification of G-Protein Coupled Receptors

, 12(14): 1797 - 1808

Ignacio Torrecilla and Andrew B. Tobin


DOI: 10.2174/138161206776873716




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