Contents

Current Pharmaceutical Design, Volume 11 - Number 21

Editorial [Hot Topic: Ion Channels as a Target for Drug Design )Executive Editor: Kwok-Keung Tai)]

, 11(21): 2669 - 2670

Kwok-Keung Tai


DOI: 10.2174/1381612054546860




Mechanism of Local Anesthetic Drug Action on Voltage-Gated Sodium Channels

, 11(21): 2671 - 2686

H. A. Fozzard, P. J. Lee and G. M. Lipkind


DOI: 10.2174/1381612054546833




Activation and Activators of TRPV1 and Their Pharmaceutical Implication

, 11(21): 2687 - 2698

Young-Ger Suh and Uhtaek Oh


DOI: 10.2174/1381612054546789




Insulin Secretagogues, Sulfonylurea Receptors and KATP Channels

, 11(21): 2699 - 2716

J. Bryan, A. Crane, W. H. Vila-Carriles, A. P. Babenko and L. Aguilar-Bryan


DOI: 10.2174/1381612054546879




Physiology and Pharmacology of Two-Pore Domain Potassium Channels

, 11(21): 2717 - 2736

Donghee Kim


DOI: 10.2174/1381612054546824




Ion Channel Defects in Idiopathic Epilepsies

, 11(21): 2737 - 2752

Holger Lerche, Yvonne G. Weber, Karin Jurkat-Rott and Frank Lehmann-Horn


DOI: 10.2174/1381612054546815




Intracellular Chloride Channels: Critical Mediators of Cell Viability and Potential Targets for Cancer Therapy

, 11(21): 2753 - 2764

Kwang S. Suh and Stuart H. Yuspa


DOI: 10.2174/1381612054546806




The TRPM Cation Channels in the Immune Context

, 11(21): 2765 - 2778

C. Schmitz and A.- L. Perraud


DOI: 10.2174/1381612054546851




Beyond Single Pathway Inhibition: MEK Inhibitors as a Platform for the Development of Pharmacological Combinations with Synergistic Anti-Leukemic Effects

, 11(21): 2779 - 2795

M. Milella, C. M. Precupanu, C. Gregorj, M. R. Ricciardi, M. T. Petrucci, S. M. Kornblau, A. Tafuri and M. Andreeff


DOI: 10.2174/1381612054546842




Targeting Central Plasticity: A New Direction of Finding Painkillers

, 11(21): 2797 - 2807

Min Zhuo


DOI: 10.2174/1381612054546798




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