Contents

Current Pharmaceutical Design, Volume 10 - Number 16

Preface [Hot Topic: Signal Transduction Therapy: Facts and Visions Executive Editor: Claus Liebmann ]

, 10(16): ii

Claus Liebmann


DOI: 10.2174/1381612043384349




Flt3 Receptor Tyrosine Kinase as a Drug Target in Leukemia

, 10(16): 1867 - 1883

Dirk Schmidt-Arras, Joachim Schwable, Frank- D. Bohmer and Hubert Serve


DOI: 10.2174/1381612043384394




Targeting MAPK Signalling: Prometheus Fire or Pandoras Box?

, 10(16): 1885 - 1905

Simone Boldt and Walter Kolch


DOI: 10.2174/1381612043384420




MEK Inhibitors: A Therapeutic Approach to Targeting the Ras-MAP Kinase Pathway in Tumors

, 10(16): 1907 - 1914

Judith S. Sebolt-Leopold


DOI: 10.2174/1381612043384439




Phosphoinositide 3-Kinases as Targets for Therapeutic Intervention

, 10(16): 1915 - 1922

Reinhard Wetzker and Christian Rommel


DOI: 10.2174/1381612043384402




The Role of Protein Kinase C-alpha (PKC-α) in Cancer and its Modulation by the Novel PKC-α-Specific Inhibitor Aprinocarsen

, 10(16): 1923 - 1936

A- R. Hanauske, Karen Sundell and Michael Lahn


DOI: 10.2174/1381612043384376




G Protein-Coupled Receptors and their Signaling Pathways: Classical Therapeutical Targets Susceptible to Novel Therapeutic Concepts

, 10(16): 1937 - 1958

Claus Liebmann


DOI: 10.2174/1381612043384367




Monitoring Therapy with Gene Expression Profiling Reveals Physiological Differences in Drug Action

, 10(16): 1959 - 1968

S. Wolfl, A. Burchert and T. C. Kroll


DOI: 10.2174/1381612043384385




Tumor Intracellular Redox Status and Drug Resistance-Serendipity or a Causal Relationship?

, 10(16): 1969 - 1977

Shazib Pervaiz and Marie-Veronique Clement


DOI: 10.2174/1381612043384411




Hirudo medicinalis: Avascular Tissues for Clear-Cut Angiogenesis Studies?

, 10(16): 1979 - 1988

Magda de Eguileor, Gianluca Tettamanti, Annalisa Grimaldi, Gianpaolo Perletti, Terenzio Congiu, Liliana Rinaldi and Roberto Valvassori


DOI: 10.2174/1381612043384358




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