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Current Pharmaceutical Design

Volume 25, 46 Issues, 2019
ISSN: 1873-4286 (Online)
ISSN: 1381-6128 (Print)
This journal supports open access

Articles Ahead of Print

Human-Derived Organ-on-a-Chip for Personalized Drug Development


Yasamin A. Jodat , Min Gyeong Kang, Kiavash Kiaee, Gyeong Jin Kim, Angel Flores Huidobro Martinez, Aliza Rosenkranz, Hojae Bae * and Su Ryon Shin*


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10-Phenyltriazoyl Artemisinin is a Novel P-glycoprotein Inhibitor that Suppresses the Overexpression and Function of P-glycoprotein


Dong-Hwan Lee*, Md. Hasanuzzaman*, Daeho Kwon, Hye-Young Choi, So Myoung Kim, Dong Jin Kim, Dong Ju Kang, Tae-Ho Hwang, Hyung-Hoi Kim, Ho Jung Shin, Jae-Gook Shin, Sangtae Oh, Seokjoon Lee and So Won Kim


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Biosimilars of Adalimumab in IBD: Are we Ready for that?


Marjorie Argollo, Gionata Fiorino, Daniela Gilardi, Federica Furfaro, Giulia Roda, Laura Loy, Mariangela Allocca, Laurent Peyrin-Biroulet and Silvio Danese*


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ANGPTL3 Mutations in Unrelated Chinese Han Patients with Familial Hypercholesterolemia


Yunyun Yang, Song Yang, Xiaolu Jiao, Juan Li, Miaomiao Zhu, Luya Wang and Yanwen Qin*


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Anti-adhesion Molecules in IBD: Does Gut Specifity Really Make the Difference?


Ferdinando D’Amico, Giulia Roda, Laurent Peyrin-Biroulet and Silvio Danese*


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Mineralocorticoid Receptor Antagonists in Essential and Resistant Hypertension


Konstantinos P. Imprialos, Sofia Bouloukou, Georgios Kerpiniotis, Alexandra Katsimardou, Dimitrios Patoulias, Constantinos Bakogiannis and Charles Faselis*


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Boosting the Limited Use of Mineralocorticoid Receptor Antagonists Through New Agents for Hyperkalemia


Vasilios G. Athyros*, Alexandros G. Sachinidis, Ioanna Zografou, Elisavet Simoulidou, Alexia Piperidou, Nikiforos Stavropoulos and Asterios Karagiannis


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The Role of Mineralocorticoid Receptor Antagonists in Heart Failure with Reduced Ejection Fraction


Vasilios Papademetriou*, Maria Toumpourleka, Konstantinos P. Imprialos, Sofia Alataki, Alexandros Manafis and Konstantinos Stavropoulos


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Future Anti-aldosterone Agents


Kyriakos Dimitriadis*, Constantinos Tsioufis, Panayotis Iliakis, Alexandros Kasiakogias, Ioannis Andrikou, Ioannis Leontsinis, Dimitrios Konstantinidis and Dimitrios Tousoulis


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Adverse Effects of Mineralocorticoid Receptor Antagonist Administration


Manolis S. Kallistratos*, Andreas Pittaras, Iakovos Theodoulidis, Charris Grassos, Leonidas E. Poulimenos and Athanasios J. Manolis


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Nanocrystals: An Overview of Fabrication, Characterization and Therapeutic Applications in Drug Delivery


Vishwas P. Pardhi, Tejesh Verma, S. J.S. Flora, Hardik Chandasana* and Rahul Shukla*


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3D Printing in Personalized Drug Delivery


Afsana, Vineet Jain, Nafis Haider and Keerti Jain*


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Lung on a Chip for Drug Screening and Design


Ahmet Akif Kızılkurtlu, Tuğçe Polat, Gül Banu Aydın and Ali Akpek*


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Bioengineered in vitro Vascular Models for Applications in Interventional Radiology


Xiaoyun Li*, Seyed Masoud Moosavi-Basri, Rahul Sheth, Xiaoying Wang and Yu Shrike Zhang*


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Current Strategies and Future Perspectives of Skin-on-a-Chip Platforms: Innovations, Technical Challenges and Commercial Outlook


Ayça Bal Öztürk*, Beatrice Miccoli, Meltem Avci-Adali, Ferzaneh Mogtader, Fatemeh Sharifi, Berivan Çeçen, Gökçen Yaşayan, Dries Braeken and Emine Alarcin


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Nanotechnology: Revolutionizing the Science of Drug Delivery


Mohini Mishra, Pramod Kumar*, Jitendra Singh Rajawat, Ruchi Malik, Gitanjali Sharma and Amit Modgil


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The Application of Microfluidic Techniques on Tissue Engineering in Orthopaedics


Lingtian Wang, Dajun Jiang, Qiyang Wang, Qing Wang, Weitao Jia* and Haoran Hu


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Sensor-free and Sensor-based Heart-on-a-chip Platform: A Review of Design and Applications


Hao Wan, Chenlei Gu, Ying Gan, Weixin Wei, Kai Zhu*, Ning Hu* and Ping Wang*


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Diabetes-induced Alterations in HDL Subfractions Distribution


Marek Femlak, Anna Gluba-Brzozka*, Beata Franczyk and Jacek Rysz


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The Mechanisms of Actions of Aldosterone and its Antagonists in Cardiovascular Disease


Panteleimon Pantelidis, Michail Sideris, Margus Viigimaa, Konstantinos Avranas, Pavlos Deligkaris, Ioanna Zografou and Dragan Lovic*


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Modulation of CD44, EGFR and RAC Pathway Genes (WAVE Complex) in Epithelial Cancers


Pranathi Tata, Piyush Gondaliya, Aditya Sunkaria, Akshay Srivastava and Kiran Kalia*


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Advances in Ultrasound Mediated Transdermal Drug Delivery


Saloni Daftardar, Rabin Neupane, Sai HS. Boddu*, Jwala Renukuntla and Amit Tiwari


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Advanced Approaches of Bioactive Peptide Molecules and Protein Drug Delivery Systems


Nagarani Thotakura, Lokesh Kaushik, Vipin Kumar, Simran Preet and Penke Vijaya Babu*


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Recent Advances in Half-life Extension Strategies for Therapeutic Peptides and Proteins


Huanbo Tan, Wencheng Su, Wenyu Zhang, Pengju Wang, Michael Sattler and Peijian Zou*


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Pharmacotherapy of Myopic Choroidal Neovascularization


Hacer Isildak, Stephen G. Schwartz* and Harry W. Flynn


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Pharmacological Adjuncts to Vitrectomy Surgery


Maria Cristina Savastano*, Alfonso Savastano and Stanislao Rizzo


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Current Drugs and Nutraceuticals for the Treatment of Patients with Dyslipidemias


Michele Scognamiglio, Dario Costa*, Antonio Sorriento and Claudio Napoli


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Monocyte as an Emerging Tool for Targeted Drug Delivery: A Review


Fakhara Sabir, Rai Khalid Farooq, Asim.ur.Rehman and Naveed Ahmed*


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Pharmacotherapy of Vitreomacular Traction


Ran Wan *, Thomas Hong, Yasser Tariq and Andrew Chang


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Pharmacotherapy of Central Serous Chorioretinopathy: A Review of the Current Treatments


Pierluigi Iacono*, Lisa Toto, Costanzo Eliana, Monica Varano and Maria Cristina Parravano


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Emerging Therapeutic Targets in Oncologic Photodynamic Therapy


Gina Manda*, Mihail Eugen Hinescu, Ionela Victoria Neagoe, Luis Filipe Vieira Ferreira, Rica Boscencu, Paul Vasos, Selma Huveyda Basaga and Antonio Cuadrado


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Potential of Natural Biomaterials in Nano-scale Drug Delivery


Chahinez Houacine, Sakib Saleem Yousaf, Iftikhar Khan, Rajneet Kaur Khurana and Kamalinder K. Singh*


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New Perspectives on the Efficacy of Gallic Acid in Cosmetics & Nanocosmeceuticals


Barkat Ali Khan, Tariq Mahmood*, Farid Menaa, Yasser Shahzad, Abid Mehmood Yousaf, Talib Hussain and Sidhartha D. Ray


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3D Printing Technology in Design of Pharmaceutical Products


Ameeduzzafar, Md. Rizwanullah, Syed Nasir Abbas Bukhari, Mohd Amir, Muhammad Masood Ahmed and Mohammad Fazil*


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3D Printing Technology in Customized Drug Delivery System: Current State of the Art, Prospective and the Challenges


Farooq Ali Khan, Kaushik Narasimhan, CSV Swathi, Sayyad Mustak, Gulam Mustafa, Mohammad Zaki Ahmad and Sohail Akhter *


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Role of Polymers in 3D Printing Technology for Drug Delivery - An Overview


Ankit Jain, Kuldeep K. Bansal*, Ankita Tiwari, Ari Rosling and Jessica M. Rosenholm*


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Advances in Nanoparticle-based Delivery of Next Generation Peptide Nucleic Acids


Shipra Malik, Brenda Asmara, Zoe Moscato, Jatinder Kaur Mukker and Raman Bahal*


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Small Molecules as PD-1/PD-L1 Pathway Modulators for Cancer Immunotherapy


Peifu Jiao, Qiaohong Geng*, Peng Jin, Gaoxing Su, Houyun Teng, Jinlong Dong and Bing Yan*


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A Critical Review on 3D-printed Dosage Forms


Ilias El Aita, Hanna Ponsar and Julian Quodbach*


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3D Printing Methods for Pharmaceutical Manufacturing: Opportunity and Challenges


Musarrat Husain Warsi*, Mohammad Yusuf, Majed Al Robaian, Maria Khan, Hashem Alsaab, Abdul Muheem and Saba Khan*


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Targeting lncRNAs for Cardiovascular Therapeutics in Coronary Artery Disease


Dongsheng Yu, Chuanfeng Tang, Peiyu Liu, Weichun Qian* and Liang Sheng*


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