Contents

Current Pharmaceutical Biotechnology, Volume 9 - Number 6

Editorial [Hot Topic: Therapeutic Antibodies and Derivatives: From the Bench to the Clinic(Guest Editor: Alain Beck)]

, 9(6): 421 - 422

A. Beck, T. Wurch and N. Corvaia


DOI: 10.2174/138920108786786420




Monoclonal Antibodies as Innovative Therapeutics

, 9(6): 423 - 430

Janice M. Reichert


DOI: 10.2174/138920108786786358




Monoclonal Antibodies - Regulatory Challenges

, 9(6): 431 - 438

Christian K. Schneider


DOI: 10.2174/138920108786786394




Phage Display Derived Therapeutic Antibodies

, 9(6): 439 - 446

Holger Thie, Torsten Meyer, Thomas Schirrmann, Michael Hust and Stefan Dubel


DOI: 10.2174/138920108786786349




Development and Production of Commercial Therapeutic Monoclonal Antibodies in Mammalian Cell Expression Systems: An Overview of the Current Upstream Technologies

, 9(6): 447 - 467

Michel Chartrain and Lily Chu


DOI: 10.2174/138920108786786367




Heterogeneity of Monoclonal Antibodies Revealed by Charge-Sensitive Methods

, 9(6): 468 - 481

J. Vlasak and R. Ionescu


DOI: 10.2174/138920108786786402




Trends in Glycosylation, Glycoanalysis and Glycoengineering of Therapeutic Antibodies and Fc-Fusion Proteins

, 9(6): 482 - 501

Alain Beck, Elsa Wagner-Rousset, Marie-Claire Bussat, Maryline Lokteff, Christine Klinguer-Hamour, Jean-François Haeuw, Liliane Goetsch, Thierry Wurch, Alain Van Dorsselaer and Nathalie Corvaia


DOI: 10.2174/138920108786786411




Development of Novel Protein Scaffolds as Alternatives to Whole Antibodies for Imaging and Therapy: Status on Discovery Research and Clinical Validation

, 9(6): 502 - 509

T. Wurch, P. Lowe, V. Caussanel, C. Bes, A. Beck and N. Corvaia


DOI: 10.2174/138920108786786385




The Database dbEST Correctly Predicts Gene Expression in Colon Cancer Patients

, 9(6): 510 - 515

M. Radeva, T. Hofmann, B. Altenberg, H. Mothes, K. K. Richter, B. Pool-Zobel and K. O. Greulich


DOI: 10.2174/138920108786786330




LXR-Agonists Regulate ApoM Expression Differentially in Liver and Intestine

, 9(6): 516 - 521

Emine Calayir, Tatjana M. Becker, Adelheid Kratzer, Birgit Ebner, Ute Panzenbock, Jasminka Stefujl and Gerhard M. Kostner


DOI: 10.2174/138920108786786376




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