Contents

Current Pharmaceutical Biotechnology, Volume 12 - Number 10

Editorial [Hot Topic: Advanced Analytical Strategies for Recombinant Therapeutic Proteins (Guest Editor: Giancarlo Aldini)]

, 12(10): 1507

Giancarlo Aldini


DOI: 10.2174/138920111798357366




Structural Characterization of Recombinant Therapeutic Proteins by Circular Dichroism

, 12(10): 1508 - 1516

Carlo Bertucci, Marco Pistolozzi and Angela De Simone


DOI: 10.2174/138920111798357276




Advanced Mass Spectrometry-Based Methods for the Analysis of Conformational Integrity of Biopharmaceutical Products

, 12(10): 1517 - 1529

Cedric E. Bobst and Igor A. Kaltashov


DOI: 10.2174/138920111798357311




Analytical Approaches for Assessing Aggregation of Protein Biopharmaceuticals

, 12(10): 1530 - 1536

Elena Garcia-Fruitos, Esther Vazquez, Nuria Gonzalez-Montalban, Neus Ferrer-Miralles and Antonio Villaverde


DOI: 10.2174/138920111798357339




Capturing and Amplifying Impurities from Recombinant Therapeutic Proteins Via Combinatorial Peptide Libraries: A Proteomic Approach

, 12(10): 1537 - 1547

Pier Giorgio Righetti, Egisto Boschetti and Elisa Fasoli


DOI: 10.2174/138920111798357285




Mass Spectrometric Strategies and Their Applications for Molecular Mass Determination of Recombinant Therapeutic Proteins

, 12(10): 1548 - 1557

Marina Carini, Luca Regazzoni and Giancarlo Aldini


DOI: 10.2174/138920111798357348




Electron Transfer Dissociation of Modified Peptides and Proteins

, 12(10): 1558 - 1567

Yuping Zhou, Jia Dong and Richard W. Vachet


DOI: 10.2174/138920111798357230




Characterization of a Recombinant Influenza Vaccine Candidate Using Complementary LC-MS Methods

, 12(10): 1568 - 1579

Hongwei Xie, Catalin Doneanu, Weibin Chen, Joseph Rininger and Jeffery R. Mazzeo


DOI: 10.2174/138920111798357447




Development of a STAT5 Phosphorylation Assay as a Rapid Bioassay to Assess Interleukin-7 Potency

, 12(10): 1580 - 1588

C. Zumpe, K. Engel, N. Wiedemann, A.U. Metzger, M. Pischetsrieder and C.L. Bachmann


DOI: 10.2174/138920111798357294




Editorial [Hot Topic: Analgesic Drug Discovery: Promising Future (Guest Editor: Anindya Bhattacharya)]

, 12(10): 1589

Anindya Bhattacharya


DOI: 10.2174/138920111798357375




Rodent Models of Persistent Pain in Drug Discovery and Development

, 12(10): 1590 - 1595

William A. Eckert


DOI: 10.2174/138920111798357456




A Review of Current Animal Models of Osteoarthritis Pain

, 12(10): 1596 - 1612

Warren N. D'Souza, Gordon Y. Ng, Bradley D. Youngblood, Wayne Tsuji and Sonya G. Lehto


DOI: 10.2174/138920111798357320




Fibromyalgia: Mechanisms, Current Treatment and Animal Models

, 12(10): 1613 - 1626

Jill-Desiree Brederson, Michael F. Jarvis, Prisca Honore and Carol S. Surowy


DOI: 10.2174/138920111798357258




Evolving Cancer Pain Treatments: Rational Approaches to Improve the Quality of Life for Cancer Patients

, 12(10): 1627 - 1643

Kelly L. Knopp, Eric S. Nisenbaum and Stephen P. Arneric


DOI: 10.2174/138920111798357267




The Role of Endocannabinoids in Pain Modulation and the Therapeutic Potential of Inhibiting their Enzymatic Degradation

, 12(10): 1644 - 1659

L. J. Alvarez-Jaimes and J. A. Palmer


DOI: 10.2174/138920111798357357




Biologic Drugs for Analgesia: Redefining the Opportunity

, 12(10): 1660 - 1670

Jane Hughes, Jonathan P. Hatcher and Iain P. Chessell


DOI: 10.2174/138920111798357384




CGRP Receptor Antagonists: Toward a Novel Migraine Therapy

, 12(10): 1671 - 1680

C. A. Salvatore and S. A. Kane


DOI: 10.2174/138920111798357401




Metabotropic Glutamate Receptors as Targets for Analgesia: Antagonism, Activation, and Allosteric Modulation

, 12(10): 1681 - 1688

Michael C. Montana and Robert W. Gereau


DOI: 10.2174/138920111798357438




The Dynamic TRPA1 Channel: A Suitable Pharmacological Pain Target?

, 12(10): 1689 - 1697

Sheldon R. Garrison and Cheryl L. Stucky


DOI: 10.2174/138920111798357302




The Physiology, Pharmacology and Future of P2X7 as An Analgesic Drug Target: Hype or Promise?

, 12(10): 1698 - 1706

Anindya Bhattacharya, Robert A. Neff and Alan D. Wickenden


DOI: 10.2174/138920111798357429




Fractalkine/CX3CR1 Signalling in Chronic Pain and Inflammation

, 12(10): 1707 - 1714

Anna K. Clark, Amelia A. Staniland and Marzia Malcangio


DOI: 10.2174/138920111798357465




Targeting Voltage-Gated Sodium Channels for Treating Neuropathic and Inflammatory Pain

, 12(10): 1715 - 1719

Charles J. Cohen


DOI: 10.2174/138920111798357249




Bv8-Prokineticins and their Receptors: Modulators of Pain

, 12(10): 1720 - 1727

Lucia Negri and Roberta Lattanzi


DOI: 10.2174/138920111798357410




GCH1, BH4 and Pain

, 12(10): 1728 - 1741

Alban Latremoliere and Michael Costigan


DOI: 10.2174/138920111798357393




Webmaster Contact: info@benthamscience.org
Copyright © 2018 Bentham Science