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Endorsements

"Current Pharmaceutical Biotechnology presents the latest developments in the area of biotechnology. This is strongly recommended."

Robert Huber
Nobel Laureate

Forthcoming Special Issues

PREECLAMPSIA - AETIOPATHOGENESIS AND CLINICAL MANAGEMENT


Guest Editor(s): Marzena Laskowska
Tentative Publication Date: March, 2018
Submit Abstract via Email Download Description
Published Special Issues

Molecular, cellular and pharmaceutical aspects of autologous grafts for perimplant hard and soft tissue defects


Current Pharmaceutical Biotechnology, Volume 18, Number 1
Guest Editor(s): Cieslik Bielecka

Authors' Comments
No doubt we had a great experience with Bentham Science Publishers as the article processing time is less as compared to many other reputed journals.

Nupur Jauhari
(Department of Biotechnology, Nupur Jauhari, Navneeta Bharadvaja, Delhi Technological University, Delhi, India)


Current Pharmaceutical Biotechnology

,

Volume 19

-

Number 3



Biography   Open Access





Review Article

Intestinal Crosstalk between Microbiota and Serotonin and its Impact on Gut Motility

, 19(3): 190 - 195

Xiaolong Ge, Junhai Pan, Yichang Liu, Hongkan Wang, Wei Zhou* and Xianfa Wang


DOI: 10.2174/1389201019666180528094202






Review Article

Naringenin and its Nano-formulations for Fatty Liver: Cellular Modes of Action and Clinical Perspective

, 19(3): 196 - 205

Mehdi Zobeiri, Tarun Belwal, Fatemeh Parvizi, Rozita Naseri, Mohammad H. Farzaei*, Seyed F. Nabavi, Antoni Sureda and Seyed M. Nabavi


DOI: 10.2174/1389201019666180514170122






Review Article

Potential Use of Pentoxifylline in Cancer Therapy

, 19(3): 206 - 216

Grzegorz Golunski*, Anna Woziwodzka and Jacek Piosik*


DOI: 10.2174/1389201019666180528084641






Research Article





Research Article

Establishment of Novel Reporter Cells Stably Maintaining Transcription Factor-driven Human Secreted Alkaline Phosphatase Expression

, 19(3): 224 - 231

Riho Kurata, Asuka Kumagai, Xiaofeng Cui, Masamitsu Harada, Jun Nagai, Yasuhiro Yoshida, Kei-ichi Ozaki , Yoshimasa Tanaka and Tomo Yonezawa*


DOI: 10.2174/1389201019666180418093334






Research Article

High Level of Menaquinone-7 Production by Milking Menaquinone-7 with Biocompatible Organic Solvents

, 19(3): 232 - 239

Dinali Ranmadugala, Alireza Ebrahiminezhad*, Merilyn Manley-Harris, Younes Ghasemi and Aydin Berenjian*


DOI: 10.2174/1389201019666180515115534






Research Article





Snake Venom, A Natural Library of New Potential Therapeutic Molecules: Challenges and Current Perspectives


Rodrigo Simoes-Silva, Jorge Alfonso, Ana Gomez, Rudson J. Holanda, Juliana C. Sobrinho, Kayena D. Zaqueo, Leandro S. Moreira-Dill, Anderson M. Kayano, Fernando P. Grabner, Saulo L. da Silva, Jose R. Almeida, Rodrigo G. Stabeli, Juliana P. Zuliani and Andreimar M. Soares*


View Abstract View on PubMed


Verification of LC-MS Bioanalysis by nSMOL in Human Serum between Original and Biosimilar Therapeutic Antibody Infliximab


Noriko Iwamoto, Kotoko Yokoyama, Megumi Takanashi, Atsushi Yonezawa, Kazuo Matsubara and Takashi Shimada*


View Abstract View on PubMed


Beneficial Morphofunctional Changes Promoted by Sildenafil in Resistance Vessels in the Angiotensin II-Induced Hypertension Model


Ananda T. Dias, Marcos A. S. Leal, Tadeu C. Zanardo, Gisele M. Alves, Marcella L. Porto, Breno V. Nogueira, Agata L. Gava, Bianca P. Campagnaro, Thiago M. C. Pereira, Silvana S. Meyrelles, Manuel Campos-Toimil and Elisardo C. Vasquez*


View Abstract View on PubMed


Development of MTL-CEBPA: Small Activating RNA Drug for Hepatocellular Carcinoma


Ryan L. Setten, Helen L. Lightfoot, Nagy A. Habib and John J. Rossi*


View Abstract View on PubMed


Cytotoxicity, Genotoxicity, Antioxidant Potential and Chemical Composition of Leaves of Campomanesia pubescens (Mart. ex DC.) O. Berg


Taline B. S. Catelan*, Camila C. S. Brum, Silvia C. Heredia-Vieira, Bruno A. Crispim, Alexeia B. Grisolia, Rafael C. S. Santos and Claudia A. L. Cardoso


View Abstract View on PubMed


Replacement Therapies in Metabolic Disease


Alexander S. Keller, T. C. Stevenson Keller , Leon J. DeLalio, Guleer Shahab, Yang Yang, Sara Murphy, Xiaohong Shu and Brant E. Isakson*


View Abstract View on PubMed


Diagnostic Biomarkers Of Epilepsy


Chiara Sueri, Sara Gasparini, Simona Balestrini, Angelo Labate, Antonio Gambardella, Emilio Russo, Antonio Leo, Silvia Casarotto, Francesca Pittau, Michele Trimboli, Vittoria Cianci, Michele Ascoli, Salvatore M. Cavalli, Giulia Ferrigno, Umberto Aguglia* and Edoardo Ferlazzo


View Abstract


HELLP Syndrome: Pathophysiology and Current Therapies


Cynthia Bean, Sharonda Harris, Augustina Addison and Kedra Wallace*


View Abstract


An Untapped Resource in the Spotlight of Medicinal Biotechnology: the Genus Scutellaria


Izabela Grzegorczyk-Karolak*, Aneta Wiktorek-Smagur and Katarzyna Hnatuszko-Konka


View Abstract


Drs. Eric Betzig, Stefan W. Hell and William E. Moerner share the 2014 chemistry Nobel for the development of super-resolved fluorescence microscopy.

“The Royal Swedish Academy of Sciences has decided to award the 2014 Nobel Prize in Chemistry to Dr. Eric Betzig at Howard Hughes Medical Institute, Ashburn, U.S.A.; Professor Stefan Hell at Max Planck Institute for Biophysical Chemistry, Göttingen, and the German Cancer Research Center, Heidelberg, Germany; and Professor William Moerner at Stanford University, Stanford, U.S.A., for the development of super-resolved fluorescence microscopy.”

Much research effort was needed to realize that single-cell and single-molecule based approaches directly affect improvements in human health. However, many of these laboratory technologies are not available in a cheap and easy version. Single-molecule based fluorescence imaging and detection have the advantages of a small volume platform, digital analysis, elimination of processing steps, real-time measurements and automation of sample preparation. In 2015, Current Pharmaceutical Biotechnology will continue in this direction with quality papers that can be expected to trigger further investigations.

Drs. Eric Betzig and William E. Moerner also developed methods and biotechniques which have enabled the study of single molecules in ongoing chemical reactions in living cells. Because now it is possible to see individual macromolecules moving about in a living cell, we can study chemistry at a single-molecule level and in real life. And this is very important to chemistry because chemistry has traditionally been about studying a large number of molecules and the effect that they have. The journal Current Pharmaceutical Biotechnology has published on this research and has been at the forefront for over more than one decade. Curr. Pharm. Biotechnol. has published thematic issues, original research and review articles about the entirely new possibilities for chemistry and for biochemistry by eminent scientists from around the world, some examples:

Establishment of Novel Reporter Cells Stably Maintaining Transcription Factor-driven Human Secreted Alkaline Phosphatase Expression

, 2018; 19(3): 224 - 231

Riho Kurata, Asuka Kumagai, Xiaofeng Cui, Masamitsu Harada, Jun Nagai, Yasuhiro Yoshida, Kei-ichi Ozaki , Yoshimasa Tanaka and Tomo Yonezawa*


DOI: 10.2174/1389201019666180418093334



CAR T-cell Therapy: A New Era in Cancer Immunotherapy

, 2018; 19(1): 5 - 18

Miliotou N. Androulla and Papadopoulou C. Lefkothea*


DOI: 10.2174/1389201019666180418095526



New Developments in CRISPR Technology: Improvements in Specificity and Efficiency

, 2017; 18(13): 1038 - 1054

Fatemeh Safari, Safar Farajnia*, Younes Ghasemi and Nosratollah Zarghami


DOI: 10.2174/1389201019666180209120533



Biologics in Inflammatory and Immunomediated Arthritis

, 2017; 18(12): 989 - 1007

Michele M. Luchetti*, Devis Benfaremo and Armando Gabrielli


DOI: 10.2174/1389201019666171226151852



Immunomodulatory Effects of Bifidobacterium longum W11 Produced Exopolysaccharide on Cytokine Production

, 2017; 18(11): 883 - 889

Rosanna Inturri*, Katia Mangano, Maria Santagati, Mariano Intrieri, Roberto Di Marco and Giovanna Blandino


DOI: 10.2174/1389201019666171226151551



Novel Insights into the Molecular Interaction of a Panduratin A Derivative with the Non Structural Protein (NS3) of Dengue Serotypes: A Molecular Dynamics Study

, 2017; 18(9): 769 - 782

Pratap Parida*, Raj Narain Singh Yadav, Budheswar Dehury, Debosree Ghosh, Namita Mahapatra, Analava Mitra and Tapan Kumar Mohanta*


DOI: 10.2174/1389201018666171122122338



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