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Current Pharmaceutical Biotechnology

Volume 22, 15 Issues, 2021
ISSN: 1873-4316 (Online)
ISSN: 1389-2010 (Print)
This journal supports open access

Aims & Scope

Current Pharmaceutical Biotechnology aims to cover all the latest and outstanding developments in Pharmaceutical Biotechnology. Each issue of the journal includes timely in-depth/mini reviews, original research articles and letters written by leaders in the field, covering a range of current topics in scientific areas of Pharmaceutical Biotechnology. Invited and unsolicited review articles are welcome. The journal encourages contributions describing research at the interface of drug discovery and pharmacological applications, involving in vitro investigations and pre-clinical or clinical studies. Scientific areas within the scope of the journal include pharmaceutical chemistry, biochemistry and genetics, molecular and cellular biology, and polymer and materials sciences as they relate to pharmaceutical science and biotechnology. In addition, the journal also considers comprehensive studies and research advances pertaining food chemistry with pharmaceutical implication. Areas of interest include:

  • DNA/protein engineering and processing
  • Synthetic biotechnology
  • Omics (genomics, proteomics, metabolomics and systems biology)
  • Therapeutic biotechnology (gene therapy, peptide inhibitors, enzymes)
  • Drug delivery and targeting
  • Nanobiotechnology
  • Molecular pharmaceutics and molecular pharmacology
  • Analytical biotechnology (biosensing, advanced technology for detection of bioanalytes)
  • Pharmacokinetics and pharmacodynamics
  • Applied Microbiology
  • Bioinformatics (computational biopharmaceutics and modeling)
  • Environmental biotechnology
  • Regenerative medicine (stem cells, tissue engineering and biomaterials)
  • Translational immunology (cell therapies, antibody engineering, xenotransplantation)
  • Industrial bioprocesses for drug production and development
  • Biosafety
  • Biotech ethics

Special Issues devoted to crucial topics, providing the latest comprehensive information on cutting-edge areas of research and technological advances, are welcome.

Current Pharmaceutical Biotechnology is an essential journal for academic, clinical, government and pharmaceutical scientists who wish to be kept informed and up-to-date with the latest and most important developments.

Current Pharmaceutical Biotechnology

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Volume 22

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Number 1









Review Article (Mini-Review)

Novel Therapeutic Approaches and Targets for Treatment of Psoriasis

, 22(1): 7 - 31

Giulia Radi, Anna Campanati*, Federico Diotallevi, Tommaso Bianchelli and Annamaria Offidani


DOI: 10.2174/1389201021666200629150231






Review Article (Mini-Review)



Review Article (Mini-Review)

Novel Therapeutic Approaches and Targets for the Treatment of Atopic Dermatitis

, 22(1): 73 - 84

Leonardo Pescitelli, Elia Rosi, Federica Ricceri , Nicola Pimpinelli and Francesca Prignano *


DOI: 10.2174/1389201021666200611112755


Current Pharmaceutical Biotechnology, Volume 22 (2021) - Number 3


This issue is in progress but contains articles that are final and fully citable.

Current Pharmaceutical Biotechnology, Volume 22 (2021) - Number 2


This issue is in progress but contains articles that are final and fully citable.

Articles Ahead of Print

A Survey on Analytical Methods for the Characterization of Green Synthesized Nanomaterials


Paolo Nicolás Catalano*, Ratiram Gomaji Chaudhary, Martín Federico Desimone and Pablo Luis Santo-Orihuela*


DOI: 10.2174/1389201022666210104122349
View Abstract View on PubMed





Mesenchymal Stromal Cell-derived Exosomes Attenuate Experimental Pulmonary Arterial Hypertension


LiLi Ge, Wen Jiang, Shanshan Zhang, Jue Wang, Qian Xin, Chao Sun, Kailin Li, Tonggang Qi and Yun Luan*


DOI: 10.2174/1389201022666201231113127
View Abstract View on PubMed


Mucoadhesive Low Molecular Chitosan Complexes to Protect rHuKGF from Proteolysis: In-vitro Characterization and FHs 74 Int Cell Proliferation Studies


Yi Na Tee, Palanirajan Vijayaraj Kumar*, Marwan Abdelmahmoud Abdelkarim Maki, Manogaran Elumalai, Shiek Abdul Kadhar Mohamed Ebrahim Habibur Rahman and Shiau-Chuen Cheah


DOI: 10.2174/1389201021666201218124450
View Abstract View on PubMed



Synthesis of Silymarin−Gold Nanoparticle Conjugate and Analysis of its Liver-Protecting Activity


Sergey Staroverov, Sergey Kozlov, Alexander Fomin, Konstantib Gabalov, Alexey Volkov, Ivan Domnitsky, Lev Dykman and Olga Guliy*


DOI: 10.2174/1389201022666210101163734
View Abstract View on PubMed




Abstracts Ahead of Print

The role of hypoxia in endometrial cancer


Yarely M. Salinas-Vera, Dolores Gallardo-Rincón, Erika Ruíz-García, Macrina B. Silva-Cázares, Carmen Sol de la Peña-Cruz and César López-Camarillo*


DOI: 10.2174/1389201022666210224130022
View Abstract


Anti-anxiety properties of selected medicinal plants


Asmatullah Khan, Muhammad Akram, Muthu Thiruvengadam*, Muhammad Daniyal, Shahbaz Ahmad Zakki, Naveed Munir, Rida Zainab*, Mojtaba Heydari, Seyed Hamdollah Mosavat, Maksim Rebezov and Mohammad Ali Shariati


DOI: 10.2174/1389201022666210122125131
View Abstract




Gold Nanoparticles as Efficient Catalysts in Organic Transformations


Irshad A. Wani, Sapan K. Jain, Huma Khan, Abul Kalam and Tokeer Ahmad*


DOI: 10.2174/1389201022666210218195205
View Abstract




The Therapeutic Effects of Dihydroartemisinin on Cisplatin-Resistant Gastric Cancer Cells


Suyun Zhang, Rui Feng, Fang Yuan, Qiong Luo, Xiangqi Chen*, Nan Li and Sheng Yang*


DOI: 10.2174/1389201022666210217114825
View Abstract


Unravelling The Immune Modulatory Effect Of Indian Spices To Impede The Transmission Of Covid-19: A Promising Approach


Aswathy R Devan, Bhagyalakshmi Nair, Ayana R Kumar, Jaggaiah N Gorantla Gorantla, T. S. Aishwarya and Lekshmi R Nath*


DOI: 10.2174/1389201022666210216144917
View Abstract


Resveratrol and cardiac fibrosis prevention and treatment


Parinaz Zivarpour, Željko Reiner, Jamal Hallajzadeh* and Liaosadat Mirsafaei


DOI: 10.2174/1389201022666210212125003
View Abstract


Published Contents

Drs. Eric Betzig, Stefan W. Hell and William E. Moerner share the 2014 chemistry Nobel for the development of super-resolved fluorescence microscopy.

“The Royal Swedish Academy of Sciences has decided to award the 2014 Nobel Prize in Chemistry to Dr. Eric Betzig at Howard Hughes Medical Institute, Ashburn, U.S.A.; Professor Stefan Hell at Max Planck Institute for Biophysical Chemistry, Göttingen, and the German Cancer Research Center, Heidelberg, Germany; and Professor William Moerner at Stanford University, Stanford, U.S.A., for the development of super-resolved fluorescence microscopy.”

Much research effort was needed to realize that single-cell and single-molecule based approaches directly affect improvements in human health. However, many of these laboratory technologies are not available in a cheap and easy version. Single-molecule based fluorescence imaging and detection have the advantages of a small volume platform, digital analysis, elimination of processing steps, real-time measurements and automation of sample preparation. In 2015, Current Pharmaceutical Biotechnology will continue in this direction with quality papers that can be expected to trigger further investigations.

Drs. Eric Betzig and William E. Moerner also developed methods and biotechniques which have enabled the study of single molecules in ongoing chemical reactions in living cells. Because now it is possible to see individual macromolecules moving about in a living cell, we can study chemistry at a single-molecule level and in real life. And this is very important to chemistry because chemistry has traditionally been about studying a large number of molecules and the effect that they have. The journal Current Pharmaceutical Biotechnology has published on this research and has been at the forefront for over more than one decade. Curr. Pharm. Biotechnol. has published thematic issues, original research and review articles about the entirely new possibilities for chemistry and for biochemistry by eminent scientists from around the world, some examples:

Editor's Choice

Potential Pharmaceutical and Food Applications of Postbiotics: A Review

, 2020; 21(15): 1576 - 1587

Aziz H. Rad, Amin Abbasi*, Hossein S. Kafil* and Khudaverdi Ganbarov


DOI: 10.2174/1389201021666200516154833



Roles and Biomedical Applications of Haemolymph Lectin

, 2020; 21(14): 1444 - 1450

Rana Kamei, Oinam S. Devi, Sorokhaibam J. Singh and Senjam S. Singh*


DOI: 10.2174/1389201021666200730123330



Screening of an Alkaline CMCase-Producing Strain and the Optimization of its Fermentation Condition

, 2020; 21(13): 1304 - 1315

Junmei Zhou, Lianghong Yin*, Chenbin Wu, Sijia Wu, Jidong Lu, Hailing Fang and Yongchang Qian*


DOI: 10.2174/1389201021666200129123818




Curcumin Therapeutic Modulation of the Wnt Signaling Pathway

, 2020; 21(11): 1006 - 1015

Milad Ashrafizadeh, Zahra Ahmadi, Reza Mohamamdinejad, Habib Yaribeygi*, Maria-Corina Serban , Hossein M. Orafai and Amirhossein Sahebkar*


DOI: 10.2174/1389201021666200305115101



Current Prospects of Nutraceuticals: A Review

, 2020; 21(10): 884 - 896

Vedant Sachdeva, Arpita Roy and Navneeta Bharadvaja*


DOI: 10.2174/1389201021666200130113441




The Physiologic Activity and Mechanism of Quercetin-Like Natural Plant Flavonoids

, 2020; 21(8): 654 - 658

Wujun Chen, Shuai Wang, Yudong Wu, Xin Shen, Shutan Xu, Zhu Guo*, Renshuai Zhang* and Dongming Xing*


DOI: 10.2174/1389201021666200212093130




Feasibility Study for Bedside Production of Recombinant Human Acid α-Glucosidase: Technical and Financial Considerations

, 2020; 21(6): 467 - 479

Mohammed H. Aldosari*, Marcel den Hartog, Hubertina Ganizada, Martijn J.W. Evers, Enrico Mastrobattista and Huub Schellekens


DOI: 10.2174/1389201021666200217113049



Open Access Articles

Leaf and Fruit Methanolic Extracts of Azadirachta indica Exhibit Antifertility Activity on Rats’ Sperm Quality and Testicular Histology

, 2021; 22(3): 400 - 407

Castillo-Maldonado Irais, Borjón-Ríos Claudia, Pedroza-Escobar David*, Sharma Ashutosh, García-Garza Rubén, Ramírez-Moreno Agustina, Vega-Menchaca M. del Carmen, Rivera-Guillén Mario-Alberto and Serrano-Gallardo Luis-Benjamín*




Salinomycin Modulates the Expression of mRNAs and miRNAs Related to Stemness in Endometrial Cancer

, 2021; 22(2): 317 - 326

Karol Talkowski*, Kamil Kiełbasiński, Wojciech Peszek, Beniamin O. Grabarek, Dariusz Boroń and Marcin Oplawski






Effect of Salinomycin on Expression Pattern of Genes Associated with Apoptosis in Endometrial Cancer Cell Line

, 2020; 21(12): 1269 - 1277

Kamil Kiełbasiński*, Wojciech Peszek, Beniamin O. Grabarek, Dariusz Boroń, Magdalena Wierzbik-Strońska and Marcin Oplawski





Differences in the Expression Pattern of mRNA Protein SEMA3F in Endometrial Cancer in vitro under Cisplatin Treatment

, 2020; 21(11): 1119 - 1128

Przemysław Kieszkowski*, Dariusz Dąbruś, Beniamin O. Grabarek and Dariusz Boroń




Analysis of the Clinical Diagnostic Value of GMFB in Cerebral Infarction

, 2020; 21(10): 955 - 963

Zhaohu Yuan*, Zhiwu Yu, Yiyu Zhang and Huikuan Yang




Plant Phenolics as Pathogen-Carrier Immunogenicity Modulator Haptens

, 2020; 21(10): 897 - 905

Castillo-Maldonado Irais, Sevilla-González María-de-la-Luz, Delgadillo-Guzmán Dealmy, Ramírez-Moreno Agustina, Cabral-Hipólito Nidia, Rivera-Guillén Mario-Alberto, Serrano-Gallardo Luis-Benjamín*, Vega-Menchaca María-del-Carmen and Pedroza-Escobar David*





The Anti-Inflammatory Effects of Anacardic Acid on a TNF-α - Induced Human Saphenous Vein Endothelial Cell Culture Model

, 2020; 21(8): 710 - 719

Burak Önal*, Deniz Özen, Bülent Demir, Duygu Gezen Ak, Erdinç Dursun, Caner Demir, Ahmet Gökhan Akkan and Sibel Özyazgan




Development of Formulation Methods and Physical Characterization of Injectable Sodium Selenite Nanoparticles for the Delivery of Sorafenib tosylate

, 2020; 21(8): 659 - 666

Sivakumar S. Moni*, Mohammad F. Alam*, Mohammed M. Safhi , Muhammad H. Sultan, Hafiz A. Makeen and Mohamed E. Elmobark




Assessment of Expression of Homeobox A5 in Endometrial Cancer on the mRNA and Protein Level

, 2020; 21(7): 635 - 641

Konrad Dziobek*, Marcin Oplawski, Nikola Zmarzły, Beniamin O. Gabarek, Robert Kiełbasiński, Kamil Kiełbasiński, Przemysław Kieszkowski, Karol Talkowski and Dariusz Boroń




Relationship between SNP rs1764391 and Susceptibility, Risk Factors, Gene-environment Interactions of Acute Myocardial Infarction in Guangxi Han Chinese Population

, 2020; 21(1): 79 - 88

Jun Li, Rui Qin, Wei Wang*, Zhou Huang, Dong-Ling Huang, Tian Li, Fan Wang, Xiang-tao Zeng, Zhong-yi Sun, Xue-feng Liu, Feng Huang and Tao Guo




Variances in the Level of COX-2 and iNOS in Different Grades of Endometrial Cancer

, 2020; 21(1): 52 - 59

Marcin Oplawski*, Konrad Dziobek, Nikola Zmarzły, Beniamin O. Grabarek, Robert Kiełbasiński, Przemysław Kieszkowski, Piotr Januszyk, Karol Talkowski, Michał Schweizer, Piotr Kras, Andrzej Plewka and Dariusz Boroń





Most Cited Articles




Review Article

Current prospects of nutraceuticals: A review

, 2020; 21(10): 884-896.

Vedant Sachdeva, Arpita Roy and Navneeta Bharadvaja*


DOI: 10.2174/1389201021666200130113441


Research Article

Enhancing the antibacterial activity of erythromycin with titanium dioxide nanoparticles against MRSA

, 2020; 21(10): 948-954.

Kaleem Ullah, Shujaat A. Khan, Abdul Mannan, Romana Khan, Ghulam Murtaza* and Muhammad A. Yameen*


DOI: 10.2174/1389201021666200128124142



Review Article

Antibiotics application strategies to control biofilm formation in pathogenic bacteria

, 2020; 21(4): 270-286.

Fazlurrahman Khan, Dung T.N. Pham, Sandra F. Oloketuyi and Young-Mog Kim*


DOI: 10.2174/1389201020666191112155905


Research Article

Design of experiment, preparation, and in vitro biological assessment of human amniotic membrane extract loaded nanoparticles

, 2020; 21(3): 256-267.

Avishan Shabani, Fatemeh Atyabi, Mohammad R. Khoshayand, Reza Mahbod, Reza A. Cohan, Iman Akbarzadeh and Haleh Bakhshandeh*


DOI: 10.2174/1389201020666191019122130



Research Article

Delonix regia a folklore remedy for diabetes; attenuates oxidative stress and modulates type ii diabetes mellitus

, 2020; 21(11): 1059-1069.

Darosham Khan, Ali Sharif*, Mehroz Zafar, Bushra Akhtar, Muhammad F. Akhtar and Sana Awan


DOI: 10.2174/1389201021666200217112244


General Research Article

Development of poly (Methyl vinyl ether-alt-maleic acid) microneedles for transdermal delivery of atorvastatin calcium

, 2020; 21(9): 852-861.

Pablo S. Castañeda, Clara L. Domínguez Delgado, Isabel M.R. Cruz, Luz M.M. Contreras, Eva M.M. Trinidad, Miriam L. Cervantes and José J. Escobar-Chávez*


DOI: 10.2174/1389201021666200217103302


Research Article

In silico studies on anti-stress compounds of ethanolic root extract of Hemidesmus indicus L.

, 2020; 21(6): 502-515.

Jayasimha R. Daddam, Basha Sreenivasulu, Katike Umamahesh*, Kotha Peddanna* and Dowlathabad M. Rao


DOI: 10.2174/1389201021666191211152754


Review Article

Recent advances in inhaled formulations and pulmonary insulin delivery systems

, 2020; 21(3): 180-193.

Haofan Liu, Xiaosong Shan, Jiaojiao Yu, Xin Li and Liandong Hu*


DOI: 10.2174/1389201020666191011152248


Review Article

Active targeting towards and inside the brain based on nanoparticles: A review

, 2020; 21(5): 374-383.

Morteza Rabiei, Soheila Kashanian*, Seyedeh S. Samavati, Shahriar Jamasb and Steven J.P. McInnes


DOI: 10.2174/1389201020666191203094057


Research Article

New folate-modified human serum albumin conjugated to cationic lipid carriers for dual targeting of mitoxantrone against breast cancer

, 2020; 21(4): 305-315.

Abbas A. Ridha, Soheila Kashanian*, Abbas H. Azandaryani, Ronak Rafipour and Elahe Mahdavian


DOI: 10.2174/1389201020666191114113022



Most Accessed Articles





Expression Profiles of MicroRNAs in Stem Cells Differentiation

, 2020; 21(10): 906-918.

Hadi Rajabi, Somayeh Aslani, Alireza Abhari* and Davoud Sanajou


DOI: 10.2174/1389201021666200219092520




Current Prospects of Nutraceuticals: A Review

, 2020; 21(10): 884-896.

Vedant Sachdeva, Arpita Roy and Navneeta Bharadvaja*


DOI: 10.2174/1389201021666200130113441


Curcumin Therapeutic Modulation of the Wnt Signaling Pathway

, 2020; 21(11): 1006-1015.

Milad Ashrafizadeh, Zahra Ahmadi, Reza Mohamamdinejad, Habib Yaribeygi*, Maria-Corina Serban , Hossein M. Orafai and Amirhossein Sahebkar*


DOI: 10.2174/1389201021666200305115101




The Effects of X-Ray Irradiation on Safety and Nutritional Value of Food: A Systematic Review Article

, 2020; 21(10): 919-926.

Zakiyeh B. Zehi, Asma Afshari, Seyyed M.A. Noori, Behrooz Jannat and Mohammad Hashemi*


DOI: 10.2174/1389201021666200219093834


A Systematic Review and Meta-Analysis: The Effectiveness of Probiotics for Viral Gastroenteritis

, 2020; 21(11): 1042-1051.

Fereshteh Ansari, Fariba Pashazadeh, Elaheh Nourollahi, Sakineh Hajebrahimi, Zachary Munn and Hadi Pourjafar*


DOI: 10.2174/1389201021666200416123931


Proteomics Analysis of Trastuzumab Toxicity in the H9c2 Cardiomyoblast Cell Line and its Inhibition by Carvedilol

, 2020; 21(13): 1377-1385.

Elham Beiranvand, Fatemeh Torkashvand, Seyed N. Ostad, Mehdi Mirzaie, Esmat M. Ardakani, Fatemeh Zandi, Soroush Sardari, Ghasem H. Salekdeh, Mohammad A. Shokrgozar and Behrouz Vaziri*


DOI: 10.2174/1389201021666200515135548


Plant Phenolics as Pathogen-Carrier Immunogenicity Modulator Haptens

, 2020; 21(10): 897-905.

Castillo-Maldonado Irais, Sevilla-González María-de-la-Luz, Delgadillo-Guzmán Dealmy, Ramírez-Moreno Agustina, Cabral-Hipólito Nidia, Rivera-Guillén Mario-Alberto, Serrano-Gallardo Luis-Benjamín*, Vega-Menchaca María-del-Carmen and Pedroza-Escobar David*


DOI: 10.2174/1389201021666200121130313



Editor-in-Chief

graphic
Nikolaos Labrou
Department of Biotechnology
Agricultural University of Athens
Athens
(Greece)
Biography
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COPE Compliant

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Journal History

Current Pharmaceutical Biotechnology was launched in 2000. Dr. Nikolaos Labrou serves as the Editor-in-Chief of the journal.
Scopus CiteScore Metrics: 1.97

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