Bentham Science Logo

Track Your Manuscript:


Current Pharmaceutical Biotechnology

Volume 21, 15 Issues, 2020
ISSN: 1873-4316 (Online)
ISSN: 1389-2010 (Print)
This journal supports open access

Ranking and Category

  • 259th of 298 in

    Biochemistry & Molecular Biology

  • 219th of 267 in

    Pharmacology & Pharmacy

Order Your Article Before Print

Aims & Scope

Current Pharmaceutical Biotechnology aims to cover all the latest and outstanding developments in Pharmaceutical Biotechnology. Each issue of the journal includes timely in-depth/mini reviews, original research articles and letters written by leaders in the field, covering a range of current topics in scientific areas of Pharmaceutical Biotechnology. Invited and unsolicited review articles are welcome. The journal encourages contributions describing research at the interface of drug discovery and pharmacological applications, involving in vitro investigations and pre-clinical or clinical studies. Scientific areas within the scope of the journal include pharmaceutical chemistry, biochemistry and genetics, molecular and cellular biology, and polymer and materials sciences as they relate to pharmaceutical science and biotechnology. In addition, the journal also considers comprehensive studies and research advances pertaining food chemistry with pharmaceutical implication. Areas of interest include:

  • DNA/protein engineering and processing
  • Synthetic biotechnology
  • Omics (genomics, proteomics, metabolomics and systems biology)
  • Therapeutic biotechnology (gene therapy, peptide inhibitors, enzymes)
  • Drug delivery and targeting
  • Nanobiotechnology
  • Molecular pharmaceutics and molecular pharmacology
  • Analytical biotechnology (biosensing, advanced technology for detection of bioanalytes)
  • Pharmacokinetics and pharmacodynamics
  • Applied Microbiology
  • Bioinformatics (computational biopharmaceutics and modeling)
  • Environmental biotechnology
  • Regenerative medicine (stem cells, tissue engineering and biomaterials)
  • Translational immunology (cell therapies, antibody engineering, xenotransplantation)
  • Industrial bioprocesses for drug production and development
  • Biosafety
  • Biotech ethics

Special Issues devoted to crucial topics, providing the latest comprehensive information on cutting-edge areas of research and technological advances, are welcome.

Current Pharmaceutical Biotechnology is an essential journal for academic, clinical, government and pharmaceutical scientists who wish to be kept informed and up-to-date with the latest and most important developments.

Current Pharmaceutical Biotechnology

,

Volume 21

-

Number 4



Biography   Open Access



Review Article



Review Article (Mini-Review)

Classical and New Pharmaceutical Uses of Bacterial Penicillin G Acylase

, 21(4): 287 - 297

Luis Cobos-Puc, Raúl Rodríguez-Herrera*, Juan C. Cano-Cabrera, Hilda Aguayo-Morales, Sonia Y. Silva-Belmares, Adriana C.F. Gallegos and José L.M. Hernández


DOI: 10.2174/1389201020666191111151642


Research Article



Research Article



Research Article

Production and Preliminary In Vivo Evaluations of a Novel in silicodesigned L2-based Potential HPV Vaccine

, 21(4): 316 - 324

Manica Negahdaripour, Navid Nezafat, Reza Heidari, Nasrollah Erfani, Nasim Hajighahramani, Mohammad B. Ghoshoon, Eskandar Shoolian, Mohammad R. Rahbar, Sohrab Najafipour, Ali Dehshahri, Mohammad H. Morowvat and Younes Ghasemi*


DOI: 10.2174/1389201020666191114104850


Research Article



Research Article



Current Pharmaceutical Biotechnology, Volume 21 (2020) - Number 5


This issue is in progress but contains articles that are final and fully citable.

Articles Ahead of Print

TNF Receptor: Fc Fusion Protein Downregulates RANKL/OPG Ratio by Inhibiting CXCL16/CXCR6 in Active Ankylosing Spondylitis


Peiyi Zhang, Shufen Zhou, Zhe Chen, Ye Tian, Qianqian Wang, Hui Li, Tiantian Zhang, Qin Guo, Meiying Wang and Chengshan Guo*


DOI: 10.2174/1389201021666200302104418
View Abstract View on PubMed


Folate-modified Graphene Oxide as the Drug Delivery System to Load Temozolomide


Li-Hua Wang, Jia-Yuan Liu, Lin Sui, Peng-Hui Zhao, Hai-Di Ma, Zhen Wei* and Yong-Li Wang*


DOI: 10.2174/1389201021666200226122742
View Abstract View on PubMed







The Effects of X-Ray Irradiation on Safety and Nutritional Value of Food: a Systematic Review Article


Zakiyeh Balouch Zehi, Asma Afshari, Seyyed Mohammad Ali Noori, Behrooz Jannat and Mohammad Hashemi*


DOI: 10.2174/1389201021666200219093834
View Abstract View on PubMed


Prevalence of Multi-Drug Resistant Tuberculosis among Tuberculosis Patients Attending Chest Clinics in Osun-State, Nigeria


Oyedeji Jimoh Gbadebo, Adeyemo Charles, Dissou Affolabi, Abiodun Tope, Alli Oyebode, Onaolapo James Olakunle, Onaolapo Yetunde Adejoke, Adesiji Yemisi and Olowe Olugbenga Adekunle*


DOI: 10.2174/1389201021666200226100242
View Abstract View on PubMed



Abstracts Ahead of Print

Tripterine is a potential anti-allergic compound


Bao-jun Zhu, Ze-quan Qian, Hui-run Yang and Ru-xia Li*


DOI: 10.2174/1389201021666200327163322
View Abstract


Should the vancomycin minimal inhibitory concentration be used as an infant critical care regular criteria?


Nadielle Bidu, Bruno Fernandes, Jucelino Conceição Filho, Regina Bastos, Joice Pedreira and Ricardo David Couto*


DOI: 10.2174/1389201021666200327162402
View Abstract




Altered Expression of MicroRNAs in the Bone Marrow of Multiple Myeloma Patients and their Relationship to Cytogenetic Aberrations


Hanaa R.M. Attia*, Amany H. Abdelrahman, Mona Hamed Ibrahim, Maha M. Eid, Ola M. Eid, Mohamed T. Sallam, Mosaad M. El Gammal and Mahmoud M. Kamel


DOI: 10.2174/1389201021666200320135139
View Abstract



Effects and Mechanism of Chlorogenic Acid on Weight Loss


Yanchun Zhong, Yueling Ding, Laiqing Li, Meina Ge, Guangguo Ban, Hongxia Yang, Jun Dai and Licheng Zhang*


DOI: 10.2174/1389201021666200318124922
View Abstract



Anticancer Potential of Calli Versus Seedling Extracts Derived from Rosmarinus officinalis and Coleus hybridus


Sarah Albogami*, Hadeer Darwish , Hala Abdelmigid , Saqer Alotaibi, Ahmed Nour El-Deen, Alaa Alnefaie and Afnan Alattas


DOI: 10.2174/1389201021666200318114817
View Abstract


Curcumin therapeutic modulation of the Wnt signaling pathway


Amirhossein Sahebkar*, Milad Ashrafizadeh, Zahra Ahmadi, Reza Mohamamdinejad, Habib Yaribeygi, Maria-Corina Serban and Hossein M. Orafai


DOI: 10.2174/1389201021666200305115101
View Abstract


Published Contents

Drs. Eric Betzig, Stefan W. Hell and William E. Moerner share the 2014 chemistry Nobel for the development of super-resolved fluorescence microscopy.

“The Royal Swedish Academy of Sciences has decided to award the 2014 Nobel Prize in Chemistry to Dr. Eric Betzig at Howard Hughes Medical Institute, Ashburn, U.S.A.; Professor Stefan Hell at Max Planck Institute for Biophysical Chemistry, Göttingen, and the German Cancer Research Center, Heidelberg, Germany; and Professor William Moerner at Stanford University, Stanford, U.S.A., for the development of super-resolved fluorescence microscopy.”

Much research effort was needed to realize that single-cell and single-molecule based approaches directly affect improvements in human health. However, many of these laboratory technologies are not available in a cheap and easy version. Single-molecule based fluorescence imaging and detection have the advantages of a small volume platform, digital analysis, elimination of processing steps, real-time measurements and automation of sample preparation. In 2015, Current Pharmaceutical Biotechnology will continue in this direction with quality papers that can be expected to trigger further investigations.

Drs. Eric Betzig and William E. Moerner also developed methods and biotechniques which have enabled the study of single molecules in ongoing chemical reactions in living cells. Because now it is possible to see individual macromolecules moving about in a living cell, we can study chemistry at a single-molecule level and in real life. And this is very important to chemistry because chemistry has traditionally been about studying a large number of molecules and the effect that they have. The journal Current Pharmaceutical Biotechnology has published on this research and has been at the forefront for over more than one decade. Curr. Pharm. Biotechnol. has published thematic issues, original research and review articles about the entirely new possibilities for chemistry and for biochemistry by eminent scientists from around the world, some examples:

Editor's Choice





Biotechnological Production of Statins: Metabolic Aspects and Genetic Approaches

, 2019; 20(15): 1244 - 1259

Roberval N.M. Neto , Edelvio de Barros Gomes , Lucas Weba-Soares , Léo R.L. Dias, Luís C.N. da Silva * and Rita de C.M. de Miranda


DOI: 10.2174/1389201020666190718165746




A Review on Targeting Nanoparticles for Breast Cancer

, 2019; 20(13): 1087 - 1107

Hasanain Gomhor J. Alqaraghuli, Soheila Kashanian* and Ronak Rafipour


DOI: 10.2174/1389201020666190731130001



In Vitro Anti-Viral Effects of Small Heat Shock Proteins 20 and 27: A Novel Therapeutic Approach

, 2019; 20(12): 1011 - 1017

Rouhollah Vahabpour, Sepehr Soleymani, Farzin Roohvand, Rezvan Zabihollahi and Azam Bolhassani*


DOI: 10.2174/1389201020666190729104648





Open Access Articles

Relationship between SNP rs1764391 and Susceptibility, Risk Factors, Gene-environment Interactions of Acute Myocardial Infarction in Guangxi Han Chinese Population

, 2020; 21(1): 79 - 88

Jun Li, Rui Qin, Wei Wang*, Zhou Huang, Dong-Ling Huang, Tian Li, Fan Wang, Xiang-tao Zeng, Zhong-yi Sun, Xue-feng Liu, Feng Huang and Tao Guo




Variances in the Level of COX-2 and iNOS in Different Grades of Endometrial Cancer

, 2020; 21(1): 52 - 59

Marcin Oplawski*, Konrad Dziobek, Nikola Zmarzły, Beniamin O. Grabarek, Robert Kiełbasiński, Przemysław Kieszkowski, Piotr Januszyk, Karol Talkowski, Michał Schweizer, Piotr Kras, Andrzej Plewka and Dariusz Boroń




Plant Phenolics and Lectins as Vaccine Adjuvants

, 2019; 20(15): 1236 - 1243

Hernández-Ramos Reyna-Margarita, Castillo-Maldonado Irais*, Rivera-Guillén Mario-Alberto, Ramírez-Moreno Agustina, Serrano-Gallardo Luis-Benjamín and Pedroza-Escobar David*




Preparation of Chitosan/Alginate-ellagic Acid Sustained-release Microspheres and their Inhibition of Preadipocyte Adipogenic Differentiation

, 2019; 20(14): 1213 - 1222

Chengshi Ding, Haidan Bi, Deya Wang, Meiling Kang, Zhongjing Tian, Yingxia Zhang, Hongkai Wang, Tianshun Zhu* and Jing Ma*




Changes in the Density of Corneal Endothelial Cells in Elderly Diabetic Patients After Combined Phacovitrectomy and Ex-PRESS Glaucoma Implants

, 2019; 20(12): 1037 - 1043

Anita Lyssek-Boroń*, Katarzyna Krysik, Magdalena Kijonka, Mateusz Osuch, Beniamin O. Grabarek and Dariusz Dobrowolski




Changes in the Expression Profile of VEGF-A, VEGF-B, VEGFR-1, VEGFR-2 in Different Grades of Endometrial Cancer

, 2019; 20(11): 955 - 963

Konrad Dziobek*, Marcin Opławski, Beniamin Oskar Grabarek, Nikola Zmarzły, Barbara Tomala, Tomasz Halski, Ewa Leśniak, Krzysztof Januszyk, Ryszard Brus, Robert Kiełbasiński and Dariusz Boroń




Changes in Expression Pattern of SEMA3F Depending on Endometrial Cancer Grade - Pilot Study

, 2019; 20(9): 727 - 732

Konrad Dziobek*, Marcin Opławski, Beniamin Grabarek, Nikola Zmarzły, Robert Kiełbasiński, Ewa Leśniak, Piotr Januszyk, Krzysztof Januszyk, Iwona Adwent, Dariusz Dąbruś, Przemysław Kieszkowski, Kamil Kiełbasiński, Agnieszka Kuś-Kierach and Dariusz Boroń




Does Nimodipine, a Selective Calcium Channel Blocker, Impair Chondrocyte Proliferation or Damage Extracellular Matrix Structures?

, 2019; 20(6): 517 - 524

Necati Kaplan, Ibrahim Yilmaz, Numan Karaarslan*, Yasin E. Kaya, Duygu Y. Sirin and Hanefi Ozbek




Evaluation of Changes in the Expression Pattern of EDIL3 in Different Grades of Endometrial Cancer

, 2019; 20(6): 483 - 488

Marcin Oplawski*, Konrad Dziobek, Nikola Zmarzły, Beniamin Grabarek, Barbara Tomala, Ewa Leśniak, Iwona Adwent, Piotr Januszyk, Dariusz Dąbruś and Dariusz Boroń




Fenoldopam Mesylate: A Narrative Review of Its Use in Acute Kidney Injury

, 2019; 20(5): 366 - 375

Annalisa Noce*, Giulia Marrone, Valentina Rovella, Andrea Busca, Caterina Gola, Michele Ferrannini and Nicola Di Daniele*




Expression of NRP-1 and NRP-2 in Endometrial Cancer

, 2019; 20(3): 254 - 260

Marcin Oplawski*, Konrad Dziobek, Beniamin Grabarek, Nikola Zmarzły, Dariusz Dąbruś, Piotr Januszyk, Ryszard Brus, Barbara Tomala and Dariusz Boroń




Gender Difference Response of Male and Female Immunodeficiency Rats Treated with Tissue-specific Biomolecules

, 2019; 20(3): 245 - 253

Liliya V. Fedulova, Alexandr A. Basov, Ekaterina R. Vasilevskaya and Stepan S. Dzhimak*




Effect of Powdered Activated Carbon as Advanced Step in Wastewater Treatments on Antibiotic Resistant Microorganisms

, 2019; 20(1): 63 - 75

Damiana Ravasi, Roger König, Pamela Principi, Giuseppe Perale and Antonella Demarta*





Expression Profile of Endoglin in Different Grades of Endometrial Cancer

, 2018; 19(12): 990 - 995

Marcin Opławski*, Konrad Dziobek, Iwona Adwent, Dariusz Dąbruś, Beniamin Grabarek, Nikola Zmarzły, Andrzej Plewka and Dariusz Boroń





Most Cited Articles


Research Article

Healthcare-associated infections due to multidrug-resistant organisms: A surveillance study on extra hospital stay and direct costs

, 2019; 20(8): 643-652.

Guglielmo Giraldi, Marzietta Montesano, Christian Napoli, Paola Frati, Raffaele La Russa, Alessandro Santurro, Matteo Scopetti and Giovanni B. Orsi*


DOI: 10.2174/1389201020666190408095811


Research Article

Tanshinone IIA promotes macrophage cholesterol efflux and attenuates atherosclerosis of apoE-/- mice by omentin-1/ABCA1 pathway

, 2019; 20(5): 422-432.

Yu-lin Tan, Han-xiao Ou, Min Zhang, Duo Gong, Zhen-wang Zhao, Ling-yan Chen, Xiao-dan Xia, Zhong-cheng Mo* and Chao-ke Tang*


DOI: 10.2174/1389201020666190404125213


Review Article

Functional biomolecule delivery systems and bioengineering in cartilage regeneration

, 2019; 20(1): 32-46.

Marta A. Szychlinska, Ugo D'Amora, Silvia Ravalli, Luigi Ambrosio, Michelino Di Rosa and Giuseppe Musumeci*


DOI: 10.2174/1389201020666190206202048


Research Article

Catheter-related bloodstream infections: A root cause analysis in a series of simultaneous Ochrobactrum anthropi infections

, 2019; 20(8): 609-614.

Benedetto Caroleo, Pasquale Malandrino, Aldo Liberto, Dario Condorelli, Federico Patanè, Aniello Maiese, Filomena Casella, Diego Geraci, Pietrantonio Ricci and Giulio Di Mizio*


DOI: 10.2174/1389201020666190405182025


Research Article

New rules on patient’s safety and professional liability for the Italian health service

, 2019; 20(8): 615-624.

Sara Albolino, Tommaso Bellandi, Simone Cappelletti, Marco Di Paolo, Vittorio Fineschi*, Paola Frati, Caterina Offidani, Michela Tanzini, Riccardo Tartaglia and Emanuela Turillazzi


DOI: 10.2174/1389201020666190408094016



Research Article

Effect of pullulan on physicochemical, microbiological, and sensory quality of yogurts

, 2019; 20(6): 489-496.

Anna Chlebowska-Śmigiel, Katarzyna Kycia, Katarzyna Neffe-Skocińska, Marek Kieliszek*, Małgorzata Gniewosz and Danuta Kołożyn-Krajewska


DOI: 10.2174/1389201020666190416151129


Review Article

Valorization of fruits by-products to unconventional sources of additives, oil, biomolecules and innovative functional foods

, 2019; 20(10): 776-786.

Charalampia Dimou, Haralabos C. Karantonis, Dimitrios Skalkos and Antonios E. Koutelidakis*


DOI: 10.2174/1389201020666190405181537


Letter

The combination of dimorphandra gardneriana galactomannan and mangiferin inhibits herpes simplex and poliovirus

, 2019; 20(3): 215-221.

Daniele Z. Rechenchoski, Nayara L. Samensari, Ligia C. Faccin-Galhardi, Raimundo R. de Almeida, Arcelina P. Cunha, Nágila M.P.S. Ricardo, Carlos Nozawa and Rosa E.C. Linhares*


DOI: 10.2174/1389201020666190307130431


Research Article

Gender difference response of male and female immunodeficiency rats treated with tissue-specific biomolecules

, 2019; 20(3): 245-253.

Liliya V. Fedulova, Alexandr A. Basov , Ekaterina R. Vasilevskaya and Stepan S. Dzhimak *


DOI: 10.2174/1389201020666190222184814



Review Article

Phytosterols and triterpenoids for prevention and treatment of metabolic-related liver diseases and hepatocellular carcinoma

, 2019; 20(3): 197-214.

Isabel Sánchez-Crisóstomo, Eduardo Fernández-Martínez *, Raquel Cariño-Cortés , Gabriel Betanzos-Cabrera and Rosa A. Bobadilla-Lugo


DOI: 10.2174/1389201020666190219122357


Review Article

Food components with the potential to be used in the therapeutic approach of mental diseases

, 2019; 20(2): 100-113.

María J.F. Fernández*, Estefanía Valero-Cases and Laura Rincon-Frutos


DOI: 10.2174/1389201019666180925120657


General Review Article

Role of probiotics in prophylaxis of Helicobacter pylori infection

, 2019; 20(2): 137-145.

Kashyapi Chakravarty and Smriti Gaur*


DOI: 10.2174/1389201020666190227203107



Most Accessed Articles

CAR T-cell Therapy: A New Era in Cancer Immunotherapy

, 2018; 19(1): 5-18.

Androulla N. Miliotou and Lefkothea C. Papadopoulou*


DOI: 10.2174/1389201019666180418095526




Phage Therapy in Clinical Practice: Treatment of Human Infections

, 2010; 11(1): 69-86.

Elizabeth Kutter, Daniel De Vos, Guram Gvasalia, Zemphira Alavidze, Lasha Gogokhia, Sarah Kuhl and Stephen T. Abedon


DOI: 10.2174/138920110790725401



Nanoparticles and Zeolites: Antibacterial Effects and their Mechanism against Pathogens

, 2019; 20(13): 1074-1086.

Maryam Azizi-Lalabadi, Mahmood Alizadeh-Sani, Arezou Khezerlou, Mina Mirzanajafi-Zanjani, Hajar Zolfaghari, Vahid Bagheri, Baharak Divband and Ali Ehsani*


DOI: 10.2174/1573397115666190708120040


Structure, Genome, Infection Cycle and Clinical Manifestations Associated with Human Papillomavirus

, 2019; 20(15): 1260-1280.

Srishti Vashisht, Harshita Mishra, Pawan K. Mishra, Adam Ekielski and Sushama Talegaonkar*


DOI: 10.2174/1389201020666190802115722



Catheter-related Bloodstream Infections: A Root Cause Analysis in a Series of Simultaneous Ochrobactrum anthropi Infections

, 2019; 20(8): 609-614.

Benedetto Caroleo, Pasquale Malandrino, Aldo Liberto, Dario Condorelli, Federico Patanè, Aniello Maiese, Filomena Casella, Diego Geraci, Pietrantonio Ricci and Giulio Di Mizio*


DOI: 10.2174/1389201020666190405182025




Editor-in-Chief

Nikolaos Labrou
Department of Biotechnology
Agricultural University of Athens
Athens
Greece

Biography View Full Editorial Board

Journal History

Current Pharmaceutical Biotechnology was launched in 2000. Dr. Nikolaos Labrou serves as the Editor-in-Chief of the journal.
Scopus CiteScore Metrics: 1.97

Advertisement

Coronaviruses-JOIN-EDITORIAL-BOARDNational Colorectal Cancer Awareness Month

Related Journals

Related eBooks

eBooks Catalog