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Current Pharmaceutical Biotechnology

Volume 22, 15 Issues, 2021
ISSN: 1873-4316 (Online)
ISSN: 1389-2010 (Print)
This journal supports open access

Aims & Scope

Current Pharmaceutical Biotechnology aims to cover all the latest and outstanding developments in Pharmaceutical Biotechnology. Each issue of the journal includes timely in-depth/mini reviews, original research articles and letters written by leaders in the field, covering a range of current topics in scientific areas of Pharmaceutical Biotechnology. Invited and unsolicited review articles are welcome. The journal encourages contributions describing research at the interface of drug discovery and pharmacological applications, involving in vitro investigations and pre-clinical or clinical studies. Scientific areas within the scope of the journal include pharmaceutical chemistry, biochemistry and genetics, molecular and cellular biology, and polymer and materials sciences as they relate to pharmaceutical science and biotechnology. In addition, the journal also considers comprehensive studies and research advances pertaining food chemistry with pharmaceutical implication. Areas of interest include:

  • DNA/protein engineering and processing
  • Synthetic biotechnology
  • Omics (genomics, proteomics, metabolomics and systems biology)
  • Therapeutic biotechnology (gene therapy, peptide inhibitors, enzymes)
  • Drug delivery and targeting
  • Nanobiotechnology
  • Molecular pharmaceutics and molecular pharmacology
  • Analytical biotechnology (biosensing, advanced technology for detection of bioanalytes)
  • Pharmacokinetics and pharmacodynamics
  • Applied Microbiology
  • Bioinformatics (computational biopharmaceutics and modeling)
  • Environmental biotechnology
  • Regenerative medicine (stem cells, tissue engineering and biomaterials)
  • Translational immunology (cell therapies, antibody engineering, xenotransplantation)
  • Industrial bioprocesses for drug production and development
  • Biosafety
  • Biotech ethics

Special Issues devoted to crucial topics, providing the latest comprehensive information on cutting-edge areas of research and technological advances, are welcome.

Current Pharmaceutical Biotechnology is an essential journal for academic, clinical, government and pharmaceutical scientists who wish to be kept informed and up-to-date with the latest and most important developments.

Current Pharmaceutical Biotechnology

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Volume 22

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Number 13



Biography   Open Access



Editorial   Open Access









Review Article

Bioinspired Reduced Graphene Oxide Based Nanohybrids for Photocatalysis and Antibacterial Applications

, 22(13): 1759 - 1781

Mayuri S. Umekar, Ganesh S. Bhusari*, Ajay K. Potbhare, Aniruddha Mondal, Bharat P. Kapgate, Martin F. Desimone* and Ratiram Gomaji Chaudhary*


DOI: 10.2174/1389201022666201231115826


Review Article

Biogenic Synthesis of Metal/Metal Oxide Nanostructured Materials

, 22(13): 1782 - 1793

Aniruddha Mondal*, Mayuri S. Umekar, Ganesh S. Bhusari*, Prashant B. Chouke, Trimurti Lambat, Sudip Mondal, Ratiram G. Chaudhary and Sami H. Mahmood*


DOI: 10.2174/1389201022666210111122911


Review Article



Current Pharmaceutical Biotechnology, Volume 22 (2021) - Number 14


This issue is in progress but contains articles that are final and fully citable.

Articles Ahead of Print


The Beneficial Effects of QIAPI 1® against Pentavalent Arsenic-Induced Lung Toxicity: A Hypothetical Model for SARS CoV2-Induced Lung Tox-icity


Arturo Solís Herrera, Narasimha M. Beeraka, Mikhail Y. Sinelnikov, Vladimir N. Nikolenko, Dimitry B. Giller, Luis Fernando Torres Solis, Liudmila M. Mikhaleva, Siva G. Somasundaram*, Cecil E. Kirkland and Gjumrakch Aliev*


DOI: 10.2174/1389201022666210412142230
View Abstract View on PubMed



Antibody Fragment and Targeted Colorectal Cancer Therapy: A Global Systematic Review


Sepideh Ghani, Niloofar Deravi, Marzieh Pirzadeh, Behnam Rafiee, Zahra Rezanejad Gatabi, Mojgan Bandehpour and Fatemeh Yarian*


DOI: 10.2174/1389201022666210810104226
View Abstract View on PubMed




Sulfated Extract of Abelmoschus Esculentus: A Potential Cancer Chemo-preventive Agent


Amira M. Gamal-Eldeen *, Hassan Amer, Cinderella A. Fahmy , Haytham Dahlawi, Asma Salman and Bassem M. Raafat


DOI: 10.2174/1389201022666210714151419
View Abstract View on PubMed





Abstracts Ahead of Print

Key Performance Indicators in Claims Management: Definition of a set of indicators for the evaluation of the Medico-Legal Activity


Matteo Scopetti*, Martina Padovano, Federico Manetti, Vittorio Gatto, Stefano D'Errico, Alessandro Santurro, Paola Frati and Vittorio Fineschi


DOI: 10.2174/1389201022666210916124851
View Abstract


Protective effects of curcumin against iron-induced toxicity


Nastaran Moinipour, Mahdi Barati, Amirhosein Sahebkar*, Milad Iranshahy and Abolfazl Shakeri


DOI: 10.2174/1389201022666210914122846
View Abstract



Escherichia coli and colorectal cancer: Unfolding the enigmatic relationship


Rogayeh Nouri, Alka Hasani, Kourosh Masnadi Shirazi, Mohammad Reza Aliand, Bita Sepehri, Simin Sotoodeh, Fatemeh Hemmati and Mohammad Ahangarzadeh Rezaee*


DOI: 10.2174/1389201022666210910094827
View Abstract


Bacterial proteomics and its application for pathogenesis studies


Mahdi Asghari Ozma, Ehsaneh Khodadadi, Mohammad Ahangarzadeh Rezaee, Mohammad Asgharzadeh, Mohammad Aghazadeh, Elham Zeinalzadeh, Khudaverdi Ganbarov and Hossein Kafil*


DOI: 10.2174/1389201022666210908153234
View Abstract


Rational design and evaluation of the recombinant multiepitope protein for serodiagnosis of rubella


Marilen Souza, Juliana Machado, Jonatas da Silva, Luana Ramos, Lais Nogueira, Patrícia Ribeiro, Daniel Dias, Josiane Santos, José Carlos Santos, Yanna Nóbrega, Amanda Souza, Sonia Freitas, Mariana Campos da Paz, Maria Felipe, Fernando Torres and Alexsandro Galdino*


DOI: 10.2174/1389201022666210907170921
View Abstract


Bacteriocins: Recent advances in application as an antimicrobial alternative


Hadis Fathizadeh, Farzaneh Pakdel, Mahmood Saffari, Davoud Davoud Esmaeili, Mansooreh Momen-Heravi, Sounkalo Dao, Khudaverdi Ganbarov and Hossein Samadi Kafil*


DOI: 10.2174/1389201022666210907121254
View Abstract




Lipid engineered nanoparticle therapy for burn wound treatment


Abdul Qadir, Usama Ahmad, Asad Ali, Aisha Shahid, Mohd. Aqil, Nausheen Khan, Athar Ali, Waleed H Almalki, Saad Alghamdi, Md Abul Barkat and Sarwar Beg


DOI: 10.2174/1389201022666210823110532
View Abstract


Published Contents

Drs. Eric Betzig, Stefan W. Hell and William E. Moerner share the 2014 chemistry Nobel for the development of super-resolved fluorescence microscopy.

“The Royal Swedish Academy of Sciences has decided to award the 2014 Nobel Prize in Chemistry to Dr. Eric Betzig at Howard Hughes Medical Institute, Ashburn, U.S.A.; Professor Stefan Hell at Max Planck Institute for Biophysical Chemistry, Göttingen, and the German Cancer Research Center, Heidelberg, Germany; and Professor William Moerner at Stanford University, Stanford, U.S.A., for the development of super-resolved fluorescence microscopy.”

Much research effort was needed to realize that single-cell and single-molecule based approaches directly affect improvements in human health. However, many of these laboratory technologies are not available in a cheap and easy version. Single-molecule based fluorescence imaging and detection have the advantages of a small volume platform, digital analysis, elimination of processing steps, real-time measurements and automation of sample preparation. In 2015, Current Pharmaceutical Biotechnology will continue in this direction with quality papers that can be expected to trigger further investigations.

Drs. Eric Betzig and William E. Moerner also developed methods and biotechniques which have enabled the study of single molecules in ongoing chemical reactions in living cells. Because now it is possible to see individual macromolecules moving about in a living cell, we can study chemistry at a single-molecule level and in real life. And this is very important to chemistry because chemistry has traditionally been about studying a large number of molecules and the effect that they have. The journal Current Pharmaceutical Biotechnology has published on this research and has been at the forefront for over more than one decade. Curr. Pharm. Biotechnol. has published thematic issues, original research and review articles about the entirely new possibilities for chemistry and for biochemistry by eminent scientists from around the world, some examples:

Editor's Choice

Green Synthesis and Applications of Nanomaterials

, 2021; 22(13): 1705 - 1747

N.B. Singh*, Preeti Jain, Anindita De and Richa Tomar


DOI: 10.2174/1389201022666210412142734



Recent Advances in Clinical Utility of Probiotics in Gastrointestinal Tract Disorders

, 2021; 22(12): 1559 - 1573

Prativa Biswasroy, Deepak Pradhan, Dipak K. Sahu, Amita Sahu, Goutam Ghosh and Goutam Rath*


DOI: 10.2174/1389201021666201029154239




Is Biotechnological Next-Generation Therapeutics Promising Enough in Clinical Development to Treat Advanced Colon Cancer?

, 2021; 22(10): 1287 - 1301

Sarubala Malayaperumal, Sushmitha Sriramulu, Antara Banerjee, M.K. Makalakshmi and Surajit Pathak*


DOI: 10.2174/1389201021666201126142716



Targeted Delivery of CRISPR/Cas13 as a Promising Therapeutic Approach to Treat SARS-CoV-2

, 2021; 22(9): 1149 - 1155

Kazem Abbaszadeh-Goudarzi, Mohammad H. Nematollahi, Hashem Khanbabaei, Hossein H. Nave, Hamid R. Mirzaei, Hossein Pourghadamyari* and Amirhossein Sahebkar *


DOI: 10.2174/1389201021666201009154517



Growing Preferences towards Analog-based Drug Discovery

, 2021; 22(8): 1030 - 1045

Mehak Dangi, Alka Khichi, Ritu Jakhar and Anil K. Chhillar*


DOI: 10.2174/1389201021666200908121409



Recent Advances in the Scaffold Engineering of Protein Binders

, 2021; 22(7): 878 - 891

Mohammad K.B. Ahmadi, Seyed A. Mohammadi, Manoochehr Makvandi, Morteza Mamouei, Mohammad Rahmati*, Hesam Dehghani and David W. Wood


DOI: 10.2174/1389201021999200824101035



Biogenesis and Application of Nickel Nanoparticles: A Review

, 2021; 22(6): 808 - 822

Siva S. Sana, Raghvendra P. Singh*, Minaxi Sharma, Atul K. Srivastava, Geetanjali Manchanda, Alok R. Rai and Zhi-Jun Zhang*


DOI: 10.2174/1389201022999210101235233





Open Access Articles

Expression Profile of EMT-related Genes and miRNAs Involved in Signal Transduction via the Wnt Pathway and Cadherins in Endometrial Cancer

, 2021; 22(12): 1663 - 1671

Nikola Zmarzły*, Ewelina Hermyt, Celina Kruszniewska-Rajs, Joanna Gola, Andrzej Witek, Urszula Mazurek, Aleksander Ostenda and Dariusz Boroń




Development and Characteristics of Novel PLGA-chitosan as a New Nanocarrier for Pentavalent Vaccine Delivery

, 2021; 22(12): 1641 - 1653

Zahra Alikhani, Nadia Kazemi-Pour*, Mehdi Shafieeardestani* and Mojtaba Noofeli




Effect of TRAF1 on Phenotypic Changes Of Kupffer Cells In Liver Transplantation Ischemic-Reperfusion

, 2021; 22(12): 1602 - 1611

Zhen Zhang, KeTing Que, Yu You, XiaoPing Zhao, DiGuang Wen, ZhiHao Feng and ZuoJin Liu*





Investigation on the Antibacterial Activity of Electronic Cigarette Liquids (ECLs): A Proof of Concept Study

, 2021; 22(7): 983 - 994

Virginia Fuochi, Massimo Caruso , Rosalia Emma, Aldo Stivala, Riccardo Polosa, Alfio Distefano and Pio M. Furneri *





Synthesis and Biological Evaluation of Amoxicillin Loaded Hybrid Material Composite Spheres Against Methicillin-Resistant Staphylococcus aureus

, 2021; 22(5): 686 - 696

Muhammad A. Yameen*, Amir Zeb, Raza E. Mustafa, Sana Mushtaq, Nargis Aman, Muhammad Samie, Khizar H. Shah and Jamshed Iqbal




Analysis of the Differences in the Expression of mRNAs and miRNAs Associated with Drug Resistance in Endometrial Cancer Cells Treated with Salinomycin

, 2021; 22(4): 541 - 548

Piotr Januszyk*, Krzysztof Januszyk, Magdalena Wierzbik-Strońska, Dariusz Boroń and Beniamin Grabarek




Leaf and Fruit Methanolic Extracts of Azadirachta indica Exhibit Antifertility Activity on Rats’ Sperm Quality and Testicular Histology

, 2021; 22(3): 400 - 407

Castillo-Maldonado Irais, Borjón-Ríos Claudia, Pedroza-Escobar David*, Sharma Ashutosh, García-Garza Rubén, Ramírez-Moreno Agustina, Vega-Menchaca M. del Carmen, Rivera-Guillén Mario-Alberto and Serrano-Gallardo Luis-Benjamín*




Salinomycin Modulates the Expression of mRNAs and miRNAs Related to Stemness in Endometrial Cancer

, 2021; 22(2): 317 - 326

Karol Talkowski*, Kamil Kiełbasiński, Wojciech Peszek, Beniamin O. Grabarek, Dariusz Boroń and Marcin Oplawski






Cisplatin Changes Expression of SEMA3B in Endometrial Cancer

, 2020; 21(13): 1368 - 1376

Wojciech Peszek*, Piotr Kras, Beniamin O. Grabarek, Dariusz Boroń and Marcin Oplawski




Effect of Salinomycin on Expression Pattern of Genes Associated with Apoptosis in Endometrial Cancer Cell Line

, 2020; 21(12): 1269 - 1277

Kamil Kiełbasiński*, Wojciech Peszek, Beniamin O. Grabarek, Dariusz Boroń, Magdalena Wierzbik-Strońska and Marcin Oplawski






Most Cited Articles




Review Article

Current prospects of nutraceuticals: A review

, 2020; 21(10): 884-896.

Vedant Sachdeva, Arpita Roy and Navneeta Bharadvaja*


DOI: 10.2174/1389201021666200130113441




Research Article

Healthcare-associated infections due to multidrug-resistant organisms: A surveillance study on extra hospital stay and direct costs

, 2019; 20(8): 643-652.

Guglielmo Giraldi, Marzietta Montesano, Christian Napoli, Paola Frati, Raffaele La Russa, Alessandro Santurro, Matteo Scopetti and Giovanni B. Orsi*


DOI: 10.2174/1389201020666190408095811


Review Article

Ginger: A novel strategy to battle cancer through modulating cell signalling pathways: A review

, 2019; 20(1): 5-16.

Ahmad Almatroudi, Mohammed A. Alsahli, Faris Alrumaihi, Khaled S. Allemailem and Arshad H. Rahmani*


DOI: 10.2174/1389201020666190119142331



Review Article

Functional biomolecule delivery systems and bioengineering in cartilage regeneration

, 2019; 20(1): 32-46.

Marta A. Szychlinska, Ugo D'Amora, Silvia Ravalli, Luigi Ambrosio, Michelino Di Rosa and Giuseppe Musumeci*


DOI: 10.2174/1389201020666190206202048



Research Article

New rules on patient’s safety and professional liability for the Italian health service

, 2019; 20(8): 615-624.

Sara Albolino, Tommaso Bellandi, Simone Cappelletti, Marco Di Paolo, Vittorio Fineschi*, Paola Frati, Caterina Offidani, Michela Tanzini, Riccardo Tartaglia and Emanuela Turillazzi


DOI: 10.2174/1389201020666190408094016


Research Article

Effect of pullulan on physicochemical, microbiological, and sensory quality of yogurts

, 2019; 20(6): 489-496.

Anna Chlebowska-Śmigiel, Katarzyna Kycia, Katarzyna Neffe-Skocińska, Marek Kieliszek*, Małgorzata Gniewosz and Danuta Kołożyn-Krajewska


DOI: 10.2174/1389201020666190416151129


Review Article

Antibody therapy for the control of viral diseases: An update

, 2019; 20(13): 1108-1121.

Miriam Dibo, Eduardo C. Battocchio, Lucas M. dos Santos Souza, Matheus D. Veloso da Silva, Bruna K. Banin-Hirata, Milena M.M. Sapla, Poliana Marinello, Sérgio P.D. Rocha and Lígia C. Faccin-Galhardi*


DOI: 10.2174/1389201020666190809112704


Research Article

Medical records quality as prevention tool for healthcare-associated infections (HAIs) related litigation: A case series

, 2019; 20(8): 653-657.

Giuseppe D. Albano, Giuseppe Bertozzi, Francesca Maglietta, Angelo Montana, Giulio Di Mizio, Massimiliano Esposito, Pietro Mazzeo, Stefano D'Errico and Monica Salerno*


DOI: 10.2174/1389201020666190408102221



Most Accessed Articles


Efficacy of a Chitosan-curcumin Mixture in Treating Indomethacin-induced Acute Gastric Ulcer in Rats

, 2021; 22(14): 1919-1931.

Sineenat Kuadkaew, Suwipa Ungphaiboon, Narubodee Phdoongsombut, Sireewan Kaewsuwan and Sirima Mahattanadul*


DOI: 10.2174/1389201022666210127115427


Individual and Combined Assessment of Ser680Asn FSH Receptor and FSHβ-211 G>T Gene Polymorphisms in Ovarian Response in IVF/ICSI Program

, 2021; 22(14): 1857-1865.

Elli Anagnostou, Alexia Kafkoutsou, Despina Mavrogianni, Ekaterini Domali, Evangelia Dimitroulia, Dimitris Mathiopoulos, Peter Drakakis and Dimitris Loutradis*


DOI: 10.2174/1389201021666201029153518







Production and Immunological Evaluation of Epitope-based Preventative Pneumococcal Candidate Vaccine Comprising Immunodominant Epitopes from PspA, CbpA, PhtD and PiuA Antigens

, 2021; 22(14): 1900-1909.

Hesam Dorosti, Navid Nezafat, Reza Heidari, Mohammad B. Ghoshoon, Ahmad Gholami, Ali Dehshahri, Nasrollah Erfani, Mohammad R. Rahbar and Younes Ghasemi*


DOI: 10.2174/1389201022666201231112029



Genome-Wide Analysis of the Response of Brucella melitensis NI to Polymyxin B

, 2021; 22(14): 1891-1899.

Zhen Wang*, Jiawei Wang, Jie Cheng, Xiaowen Yang, Hai Jiang and Qingmin Wu*


DOI: 10.2174/1389201021666201218125148


Insights from Pharmaceutical Biotechnology into Phenolic Biopharmaceuticals against COVID-19

, 2021; 22(14): 1848-1856.

Nidia Cabral-Hipólito, Brenda Molina-Ramírez, María-de-la-Luz Sevilla-González, Rocío MezaVelázquez, Rubén García-Garza, Sergio-Everardo Velázquez Gauna, Irais Castillo-Maldonado, Dealmy Delgadillo-Guzmán, Mario-Alberto Rivera-Guillén*, Luis-Benjamín Serrano-Gallardo, María-del-Carmen Vega-Menchaca, Agustina Ramírez-Moreno and David Pedroza-Escobar*


DOI: 10.2174/1389201021666201104144509



Effect of TRAF1 on Phenotypic Changes Of Kupffer Cells In Liver Transplantation Ischemic-Reperfusion

, 2021; 22(12): 1602-1611.

Zhen Zhang, KeTing Que, Yu You, XiaoPing Zhao, DiGuang Wen, ZhiHao Feng and ZuoJin Liu*


DOI: 10.2174/1389201022666210111113900





Editor-in-Chief

graphic
Nikolaos Labrou
School of Food, Biotechnology and Development
Department of Biotechnology
Agricultural University of Athens
Athens
(Greece)
Biography
View Full Editorial Board

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Journal History

Current Pharmaceutical Biotechnology was launched in 2000. Dr. Nikolaos Labrou serves as the Editor-in-Chief of the journal.

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