Contents

Current Molecular Pharmacology, Volume 5 - Number 1

Editorial [Hot Topic: Evolving Drug Targets in DNA Base Excision Repair for Cancer Therapy (Guest Editor: Srinivasan Madhusudan)]

, 5(1): 1 - 2

Srinivasan Madhusudan


DOI: 10.2174/1874467211205010001




Overview of Base Excision Repair Biochemistry

, 5(1): 3 - 13

Yun-Jeong Kim and David M. Wilson III


DOI: 10.2174/1874467211205010003




Small-Molecule Inhibitors of APE1 DNA Repair Function: An Overview

, 5(1): 14 - 35

Rasha I. Al-Safi, Srinivas Odde, Yumna Shabaik and Nouri Neamati


DOI: 10.2174/1874467211205010014




APE1/Ref-1Role in Redox Signaling: Translational Applications of Targeting the Redox Function of the DNA Repair/Redox Protein APE1/Ref-1

, 5(1): 36 - 53

Mark R. Kelley, Millie M. Georgiadis and Melissa L. Fishel


DOI: 10.2174/1874467211205010036




Biological Relevance of DNA Polymerase Beta and Translesion Synthesis Polymerases to Cancer and its Treatment

, 5(1): 54 - 67

Nils H. Nicolay, Thomas Helleday and Ricky A. Sharma


DOI: 10.2174/1874467211205010054




Targeting DNA Polymerase ß for Therapeutic Intervention

, 5(1): 68 - 87

Eva M. Goellner, David Svilar, Karen H. Almeida and Robert W. Sobol


DOI: 10.2174/1874467211205010068




Base Excision Repair, the Redox Environment and Therapeutic Implications

, 5(1): 88 - 101

S. J. Storr, C. M. Woolston and S. G. Martin


DOI: 10.2174/1874467211205010088




Temozolomide: Mechanisms of Action, Repair and Resistance

, 5(1): 102 - 114

Jihong Zhang, Malcolm F.G. Stevens and Tracey D. Bradshaw


DOI: 10.2174/1874467211205010102




Base Excision Repair Factors are Promising Prognostic and Predictive Markers in Cancer

, 5(1): 115 - 124

Lucy Gossage, Christina Perry, Rachel Abbotts and Srinivasan Madhusudan


DOI: 10.2174/1874467211205010115




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