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Current Molecular Pharmacology

Volume 12, 4 Issues, 2019
ISSN: 1874-4702 (Online)
ISSN: 1874-4672 (Print)
This journal supports open access

Aims & Scope

Current Molecular Pharmacology aims to publish the latest developments in cellular and molecular pharmacology with a major emphasis on the mechanism of action of novel drugs under development, innovative pharmacological technologies, cell signaling, transduction pathway analysis, genomics, proteomics, and metabonomics applications to drug action. An additional focus will be the way in which normal biological function is illuminated by knowledge of the action of drugs at the cellular and molecular level. The journal publishes full-length/mini reviews, original research articles and thematic issues on molecular pharmacology.

Current Molecular Pharmacology is an essential journal for every scientist who is involved in drug design and discovery, target identification, target validation, preclinical and clinical development of drugs therapeutically useful in human disease.

Current Molecular Pharmacology

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Volume 12

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Number 1



Preface   Open Access



Review Article

Mechanisms for Radioprotection by Melatonin; Can it be Used as a Radiation Countermeasure?

, 12(1): 2 - 11

Peyman Amini, Hanifeh Mirtavoos-Mahyari, Elahe Motevaseli, Dheyauldeen Shabeeb, Ahmed Eleojo Musa, Mohsen Cheki, Bagher Farhood, Rasoul Yahyapour, Alireza Shirazi, Nouraddin Abdi Goushbolagh and Masoud Najafi*


DOI: 10.2174/1874467211666180802164449


Review Article



Review Article

Kinase Targets for Mycolic Acid Biosynthesis in Mycobacterium tuberculosis

, 12(1): 27 - 49

Shahinda S.R. Alsayed, Chau C. Beh, Neil R. Foster, Alan D. Payne, Yu Yu and Hendra Gunosewoyo*


DOI: 10.2174/1874467211666181025141114


Review Article

NADPH Oxidase as a Target for Modulation of Radiation Response; Implications to Carcinogenesis and Radiotherapy

, 12(1): 50 - 60

Keywan Mortezaee, Nasser Hashemi Goradel, Peyman Amini, Dheyauldeen Shabeeb, Ahmed Eleojo Musa, Masoud Najafi* and Bagher Farhood*


DOI: 10.2174/1874467211666181010154709


Research Article



Research Article



Current Molecular Pharmacology, Volume 12 (2019) - Number 2


This issue is in progress but contains articles that are final and fully citable.

Articles Ahead of Print


Convergence of Canonical and Non-Canonical Wnt Signal: Differential Kat3 Coactivator Usage


Keane K.Y. Lai*, Cu Nguyen, Kyung-Soon Lee, Albert Lee, David P. Lin, Jia-Ling Teo and Michael Kahn*


View Abstract View on PubMed


Targeting Chromatin Remodeling for Cancer Therapy


Jasmine Kaur, Abdelkader Daoud and Scott T. Eblen*


View Abstract View on PubMed




Mitochondria-Targeted Drugs


Roman A. Zinovkin* and Andrey A. Zamyatnin*


View Abstract View on PubMed



Abstracts Ahead of Print


In-vitro pre-treatment of cancer cells with TGF-β1: A novel approach of Tail vein lung cancer metastasis mouse model for anti-metastatic studies


Ghulam Jilany Khan*, Li Sun, Muhammad Abbas, Muhammad Naveed, Talha Jamshaid, Mirza Muhammad Faran Ashraf Baig and Shengtao Yuan*


View Abstract


Bafilomycin-A1 and ML9 exert different lysosomal actions to induce cell death


Soni Shaikh*, Suman K Nandy, Carles Canti and Sergio Lavandero


View Abstract



Editor's Choice





Molecular Insights of CREB and MAP-K Phosphorylation by Modafinil in Wake-Related Brain Areas

, 2018; 11(2): 140 - 148

Ramses Jimenez-Moreno, Adrian A. Farret-Ramos, Adriana Valle-Ayala, Niurka Trujillo-Paredes and Eric Murillo-Rodriguez*


DOI: 10.2174/1874467209666161214152006



The Non-Genomic Effects of the PPARβγ Agonist GW0742 on Streptozotocin Treated Rat Aorta

, 2018; 11(2): 149 - 154

Noelia Perez-Diaz, Igor Pushkarsky, Nadia Oweis, Lisa A. Lione and Louise S. Mackenzie*


DOI: 10.2174/1874467209666161229124356



The Nephroprotective Effect of N-Acetyl-L-Cysteine and Atorvastatin against Imipenem induced Nephrotoxicity

, 2018; 11(2): 155 - 161

Abeer M. Rababa`h*, Tamara B. Hijjawi, Karem H. Alzoubi, Saddam Al Demour and Mera A. Ababneh


DOI: 10.2174/1874467210666170731115928



Characterization of Imatinib Resistant CML Leukemic Stem/Initiating Cells and Their Sensitivity to CBP/Catenin Antagonists

, 2018; 11(2): 113 - 121

Yi Zhao, Kaijin Wu, Yongfeng Wu, Elizabeth Melendez, Goar Smbatyan, David Massiello and Michael Kahn*


DOI: 10.2174/1874467210666170919155739




Gamma-Decanolactone Improves Biochemical Parameters Associated with Pilocarpine-Induced Seizures in Male Mice

, 2018; 11(2): 162 - 169

Pricila Pfluger, Gabriela Gregory Regner, Vanessa Rodrigues Coelho, Lucas Lima da Silva, Leopoldo Nascimento, Cassiana Macagnan Viau, Regis Adriel Zanette, Cleonice Hoffmann, Jaqueline Nascimento Picada, Jenifer Saffi and Patricia Pereira*


DOI: 10.2174/1874467210666171002114954



Open Access Articles

Anticancer Mechanism of Lobaplatin as Monotherapy and in Combination with Paclitaxel in Human Gastric Cancer

, 2018; 11(4): 316 - 325

Suhang Hua, Xiangyu Kong, Binbin Chen, Wenxin Zhuang, Qian Sun, Wei Yang, Wenzhi Liu* and Yongxing Zhang*





Decoding Corticotropin-Releasing Factor Receptor Type 1 Crystal Structures

, 2017; 10(4): 334 - 344

Andrew S. Dore, Andrea Bortolato, Kaspar Hollenstein, Robert K.Y. Cheng, Randy J. Read and Fiona H. Marshall*






Pharmacology of L-type Calcium Channels: Novel Drugs for Old Targets?

, 2015; 8(2): 110 - 122

Jorg Striessnig, Nadine J. Ortner and Alexandra Pinggera






Most Cited Articles







Towards a Unified Theory of Calmodulin Regulation (Calmodulation) of Voltage-Gated Calcium and Sodium Channels

, 2015; 8(2): 188-205.

Manu Ben-Johny, Ivy E. Dick, Lingjie Sang, Worawan B. Limpitikul, Po Wei Kang, Jacqueline Niu, Rahul Banerjee, Wanjun Yang, Jennifer S. Babich, John B. Issa, Shin Rong Lee, Ho Namkung, Jiangyu Li, Manning Zhang, Philemon S. Yang, Hojjat Bazzazi, Paul J. Adams, Rosy Joshi-Mukherjee, Daniel N. Yue and David T. Yue


DOI: 10.2174/1874467208666150507110359



Calcium Channel Mutations in Cardiac Arrhythmia Syndromes

, 2015; 8(2): 133-142.

Matthew J. Betzenhauser, Geoffrey S. Pitt and Charles Antzelevitch


DOI: 10.2174/1874467208666150518114857




Most Accessed Articles

Temozolomide: Mechanisms of Action, Repair and Resistance

, 2012; 5(1): 102-114.

Jihong Zhang, Malcolm F.G. Stevens and Tracey D. Bradshaw


DOI: 10.2174/1874467211205010102




Sepsis: The Involvement of Platelets and the Current Treatments

, 2018; 11(4): 261-269.

Ana Carolina Antunes Naime, Jessica Oliveira Frade Ganaes and Maria Elisa Lopes-Pires*


DOI: 10.2174/1874467211666180619124531



Anticancer Mechanism of Lobaplatin as Monotherapy and in Combination with Paclitaxel in Human Gastric Cancer

, 2018; 11(4): 316-325.

Suhang Hua, Xiangyu Kong, Binbin Chen, Wenxin Zhuang, Qian Sun, Wei Yang, Wenzhi Liu* and Yongxing Zhang*


DOI: 10.2174/1874467211666180813095050





Characterization of Imatinib Resistant CML Leukemic Stem/Initiating Cells and Their Sensitivity to CBP/Catenin Antagonists

, 2018; 11(2): 113-121.

Yi Zhao, Kaijin Wu, Yongfeng Wu, Elizabeth Melendez, Goar Smbatyan, David Massiello and Michael Kahn*


DOI: 10.2174/1874467210666170919155739



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