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Current Molecular Pharmacology

Volume 12, 4 Issues, 2019
ISSN: 1874-4702 (Online)
ISSN: 1874-4672 (Print)
This journal supports open access

Ranking and Category

  • 254th of 298 in

    Biochemistry & Molecular Biology

  • 211th of 267 in

    Pharmacology & Pharmacy

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Aims & Scope

Current Molecular Pharmacology aims to publish the latest developments in cellular and molecular pharmacology with a major emphasis on the mechanism of action of novel drugs under development, innovative pharmacological technologies, cell signaling, transduction pathway analysis, genomics, proteomics, and metabonomics applications to drug action. An additional focus will be the way in which normal biological function is illuminated by knowledge of the action of drugs at the cellular and molecular level. The journal publishes full-length/mini reviews, original research articles and thematic issues on molecular pharmacology.

Current Molecular Pharmacology is an essential journal for every scientist who is involved in drug design and discovery, target identification, target validation, preclinical and clinical development of drugs therapeutically useful in human disease.

Current Molecular Pharmacology

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Volume 12

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Number 3



Perspective   Open Access

Convergence of Canonical and Non-Canonical Wnt Signal: Differential Kat3 Coactivator Usage

, 12(3): 167 - 183

Keane K.Y. Lai*, Cu Nguyen, Kyung-Soon Lee, Albert Lee, David P. Lin, Jia-Ling Teo and Michael Kahn*


DOI: 10.2174/1874467212666190304121131


Review Article   Open Access



Review Article   Open Access



Review Article   Open Access



Review Article   Open Access



Review Article   Open Access



Review Article   Open Access



Current Molecular Pharmacology, Volume 12 (2019) - Number 4


This issue is in progress but contains articles that are final and fully citable.

Articles Ahead of Print

The Role of Autophagy in Cancer Radiotherapy


Lei Li*, Wen-Ling Liu, Lei Su, Zhou-Cheng Lu and Xiu-Sheng He*


DOI: 10.2174/1874467212666190809154518
View Abstract View on PubMed




Diazoxide Modulates Cardiac Hypertrophy by Targeting H2O2 Generation and Mitochondrial Superoxide Dismutase Activity


Aline Maria Brito Lucas, Joana Varlla de Lacerda Alexandre, Maria Thalyne Silva Araújo, Cicera Edna Barbosa David, Yuana Ivia Pontes Viana, Beatriz Neves Coelho, Francisco Rodrigo Lemos Caldas, Anna Lídia Nunes Varela, Alicia Juliana Kowaltowski and Heberty Tarso Facundo*


DOI: 10.2174/1874467212666190723144006
View Abstract View on PubMed


Editor's Choice


Targeting Chromatin Remodeling for Cancer Therapy

, 2019; 12(3): 215 - 229

Jasmine Kaur, Abdelkader Daoud and Scott T. Eblen*


DOI: 10.2174/1874467212666190215112915



Convergence of Canonical and Non-Canonical Wnt Signal: Differential Kat3 Coactivator Usage

, 2019; 12(3): 167 - 183

Keane K.Y. Lai*, Cu Nguyen, Kyung-Soon Lee, Albert Lee, David P. Lin, Jia-Ling Teo and Michael Kahn*


DOI: 10.2174/1874467212666190304121131



Activation of GLP-1 and Glucagon Receptors Regulates Bile Homeostasis Independent of Thyroid Hormone

, 2019; 12(2): 139 - 146

Vishal J. Patel, Amit A. Joharapurkar*, Samadhan G. Kshirsagar, Brijesh K. Sutariya, Maulik S. Patel, Rajesh H. Bahekar and Mukul R. Jain


DOI: 10.2174/1874467212666190212112402







Molecular Insights of CREB and MAP-K Phosphorylation by Modafinil in Wake-Related Brain Areas

, 2018; 11(2): 140 - 148

Ramses Jimenez-Moreno, Adrian A. Farret-Ramos, Adriana Valle-Ayala, Niurka Trujillo-Paredes and Eric Murillo-Rodriguez*


DOI: 10.2174/1874467209666161214152006



The Non-Genomic Effects of the PPARβγ Agonist GW0742 on Streptozotocin Treated Rat Aorta

, 2018; 11(2): 149 - 154

Noelia Perez-Diaz, Igor Pushkarsky, Nadia Oweis, Lisa A. Lione and Louise S. Mackenzie*


DOI: 10.2174/1874467209666161229124356



Open Access Articles

New Insights in Cannabinoid Receptor Structure and Signaling

, 2019; 12(3): 239 - 248

Lingyan Ye, Zheng Cao, Weiwei Wang and Naiming Zhou*





Targeting Chromatin Remodeling for Cancer Therapy

, 2019; 12(3): 215 - 229

Jasmine Kaur, Abdelkader Daoud and Scott T. Eblen*




Mitochondria-Targeted Drugs

, 2019; 12(3): 202 - 214

Roman A. Zinovkin* and Andrey A. Zamyatnin*




A Contemporary Overview of PPARα/γ Dual Agonists for the Management of Diabetic Dyslipidemia

, 2019; 12(3): 195 - 201

Pitchai Balakumar*, Nanjaian Mahadevan and Ramanathan Sambathkumar




Pharmacokinetic and Pharmacodynamic Aspects of Peyote and Mescaline: Clinical and Forensic Repercussions

, 2019; 12(3): 184 - 194

Ricardo Jorge Dinis-Oliveira*, Carolina Lança Pereira and Diana Dias da Silva




Anticancer Mechanism of Lobaplatin as Monotherapy and in Combination with Paclitaxel in Human Gastric Cancer

, 2018; 11(4): 316 - 325

Suhang Hua, Xiangyu Kong, Binbin Chen, Wenxin Zhuang, Qian Sun, Wei Yang, Wenzhi Liu* and Yongxing Zhang*





Decoding Corticotropin-Releasing Factor Receptor Type 1 Crystal Structures

, 2017; 10(4): 334 - 344

Andrew S. Dore, Andrea Bortolato, Kaspar Hollenstein, Robert K.Y. Cheng, Randy J. Read and Fiona H. Marshall*






Pharmacology of L-type Calcium Channels: Novel Drugs for Old Targets?

, 2015; 8(2): 110 - 122

Jorg Striessnig, Nadine J. Ortner and Alexandra Pinggera






Most Cited Articles

Review Article

Targeting of inflammation for radiation protection and mitigation

, 2018; 11(3): 203-210.

Rasoul Yahyapour, Peyman Amini, Saeed Rezapoor, Abolhasan Rezaeyan, Bagher Farhood, Mohsen Cheki, Hengameh Fallah and Masoud Najafi*


DOI: 10.2174/1874467210666171108165641


Review Article

COX-2 in radiotherapy: A potential target for radioprotection and radiosensitization

, 2018; 11(3): 173-183.

Mohsen Cheki, Rasoul Yahyapour, Bagher Farhood, Abolhassan Rezaeyan, Dheyauldeen Shabeeb, Peyman Amini, Saeed Rezapoor and Masoud Najafi*


DOI: 10.2174/1874467211666180219102520


Review Article

Radiation protection and mitigation by natural antioxidants and flavonoids: Implications to radiotherapy and radiation disasters

, 2018; 11(4): 285-304.

Rasoul Yahyapour, Dheyauldeen Shabeeb, Mohsen Cheki, Ahmed Eleojo Musa, Bagher Farhood, Abolhasan Rezaeyan, Peyman Amini, Hengameh Fallah and Masoud Najafi*


DOI: 10.2174/1874467211666180619125653



Review Article

Brain and gut CRF signaling: Biological actions and role in the gastrointestinal tract

, 1 January 2018; 11(1): 51-71.

Yvette Tache*, Muriel Larauche, Pu-Qing Yuan and Mulugeta Million


DOI: 10.2174/1874467210666170224095741


Review Article

Opioids in the frame of new psychoactive substances network: A complex pharmacological and toxicological issue

, 1 May 2018; 11(2): 97-108.

Ludovic Ventura, Felix Carvalho and Ricardo Jorge Dinis-Oliveira*


DOI: 10.2174/1874467210666170704110146


Review Article

MicroRNAs, cancer and diet: Facts and new exciting perspectives

, 1 May 2018; 11(2): 90-96.

Maria L. Motti, Stefania D`Angelo and Rosaria Meccariello*


DOI: 10.2174/1874467210666171013123733


Review Article

NADPH oxidase as a target for modulation of radiation response; implications to carcinogenesis and radiotherapy

, 2019; 12(1): 50-60.

Keywan Mortezaee, Nasser Hashemi Goradel, Peyman Amini, Dheyauldeen Shabeeb, Ahmed Eleojo Musa, Masoud Najafi* and Bagher Farhood*


DOI: 10.2174/1874467211666181010154709



Review Article

Mechanisms for radioprotection by melatonin; can it be used as a radiation countermeasure?

, 2019; 12(1): 2-11.

Peyman Amini, Hanifeh Mirtavoos-Mahyari, Elahe Motevaseli, Dheyauldeen Shabeeb, Ahmed Eleojo Musa, Mohsen Cheki, Bagher Farhood, Rasoul Yahyapour, Alireza Shirazi, Nouraddin Abdi Goushbolagh and Masoud Najafi*


DOI: 10.2174/1874467211666180802164449


Research Article

The effect of melatonin on superoxide dismutase and glutathione peroxidase activity, and malondialdehyde levels in the targeted and the non-targeted lung and heart tissues after irradiation in xenograft mice colon cancer

, 2018; 11(4): 326-335.

Seyede Hadis Momeni Hasan Abadi, Alireza Shirazi*, Ali Mohammad Alizadeh, Vahid Changizi, Masoud Najafi, Solmaz Khalighfard and Hasan Nosrati


DOI: 10.2174/1874467211666180830150154


Research Article

Prooxidant-antioxidant balance and antioxidant properties of Thuja orientalis l: A potential therapeutic approach for diabetes mellitus

, 1 May 2018; 11(2): 109-112.

Daryoush H. Alamdari*, Malihe Aghasizadeh-Sharbaf, Maryam Mohadjerani, Gordon A. Ferns and Amir Avan


DOI: 10.2174/1874467210666170404112211


Review Article

The multi-faceted profile of corticotropin-releasing factor (CRF) family of neuropeptides and of their receptors on the paracrine/local regulation of the inflammatory response

, 1 January 2018; 11(1): 39-50.

Eirini Dermitzaki, Maria Venihaki, Christos Tsatsanis, Achille Gravanis, Pavlina D. Avgoustinaki, George Liapakis and Andrew N. Margioris*


DOI: 10.2174/1874467210666170109164430


Review Article

Mitochondria-targeted drugs

, 2019; 12(3): 202-214.

Roman A. Zinovkin* and Andrey A. Zamyatnin*


DOI: 10.2174/1874467212666181127151059




Most Accessed Articles

Temozolomide: Mechanisms of Action, Repair and Resistance

, 2012; 5(1): 102-114.

Jihong Zhang, Malcolm F.G. Stevens and Tracey D. Bradshaw


DOI: 10.2174/1874467211205010102


MiR-597 Targeting 14-3-3σ Enhances Cellular Invasion and EMT in Nasopharyngeal Carcinoma Cells

, 2019; 12(2): 105-114.

Lisha Xie, Tao Jiang, Ailan Cheng, Ting Zhang, Pin Huang, Pei Li, Gebo Wen, Fanghong Lei, Yun Huang, Xia Tang, Jie Gong, Yunpeng Lin, Jianke Kuai* and Weiguo Huang*


DOI: 10.2174/1874467212666181218113930


Does the Development of Vaccines Advance Solutions for Tuberculosis?

, 2019; 12(2): 83-104.

Manaf AlMatar*, Essam A. Makky, Husam AlMandeal, Emel Eker, Begüm Kayar, Işıl Var and Fatih Köksal


DOI: 10.2174/1874467212666181126151948





Activation of GLP-1 and Glucagon Receptors Regulates Bile Homeostasis Independent of Thyroid Hormone

, 2019; 12(2): 139-146.

Vishal J. Patel, Amit A. Joharapurkar*, Samadhan G. Kshirsagar, Brijesh K. Sutariya, Maulik S. Patel, Rajesh H. Bahekar and Mukul R. Jain


DOI: 10.2174/1874467212666190212112402


Assessment of Genotoxicity of Levosimendan in Human Cultured Lymphocytes

, 2019; 12(2): 160-165.

Abeer M. Rababa'h*, Omar F. Khabour, Karem H. Alzoubi, Dua'a Al-momani and Mera Ababneh


DOI: 10.2174/1874467212666190306164926


Mephedrone Impact on Matrix Metalloproteinases Activity - Do they Influence the Memory Processes?

, 2019; 12(2): 115-121.

Anna Boguszewska-Czubara*, Jacek Kurzepa, Grażyna Biała, Katarzyna Kaszubska, Karolina Grot, Piotr Tarkowski, Joanna Kowalczyk, Serena Silvestro, Caterina Faggio and Barbara Budzyńska


DOI: 10.2174/1874467212666190114154307


Alterations of RNA Metabolism by Proteomic Analysis of Breast Cancer Cells Exposed to Marycin: A New Optically Active Porphyrin

, 2019; 12(2): 147-159.

Elena Taverna, Maida De Bortoli, Elisa Maffioli, Cristina Corno, Emilio Ciusani, Silvio Trivulzio, Arnaldo Pinelli, Gabriella Tedeschi, Paola Perego and Italia Bongarzone*


DOI: 10.2174/1874467212666190204102112



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