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Current Molecular Medicine

Volume 19, 10 Issues, 2019
ISSN: 1875-5666 (Online)
ISSN: 1566-5240 (Print)
This journal supports open access

Ranking and Category

  • 84th of 136 in

    Medicine, Research & Experimental

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Aims & Scope

Current Molecular Medicine is an interdisciplinary journal focused on providing the readership with current and comprehensive reviews/ mini-reviews, original research articles, short communications/letters and drug clinical trial studies on fundamental molecular mechanisms of disease pathogenesis, the development of molecular-diagnosis and/or novel approaches to rational treatment. The reviews should be of significant interest to basic researchers and clinical investigators in molecular medicine. Periodically the journal invites guest editors to devote an issue on a basic research area that shows promise to advance our understanding of the molecular mechanism(s) of a disease or has potential for clinical applications.

Current Molecular Medicine

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Volume 19

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Number 8



Review Article   Open Access

Stem Cells as a Resource for Treatment of Infertility-related Diseases

, 19(8): 539 - 546

Jing Wang, Chi Liu, Masayuki Fujino, Guoqing Tong, Qinxiu Zhang, Xiao-Kang Li* and Hua Yan*


DOI: 10.2174/1566524019666190709172636


Research Article



Research Article

Schizophrenia Patient Shows a Rare Interleukin 15 Receptor alpha Variant Disrupting Signal Transduction

, 19(8): 560 - 569

Yanli Pan, Zhimin Wang, Guangping Zhang, Junhua Guo, Xuequan Zhu, Jia Zhou, Zhenrong Zhang, Zuoli Sun, Jian Yang, Abba J. Kastin, Weihong Pan, Xiaojun Wu, Jianliang Zhang, Xiaomin Wang, Chuanyue Wang and Yi He*


DOI: 10.2174/1566524019666190617172054


Research Article

Diabetic Hemodialysis: Vitamin D Supplementation and its Related Signaling Pathways Involved in Insulin and Lipid Metabolism

, 19(8): 570 - 578

Elahe S. Hosseini, Hamed H. Kashani, Hossein Nikzad, Alireza Soleimani, Hamed Mirzaei, Mohammd R. Tamadon and Zatollah Asemi*


DOI: 10.2174/1566524019666190618144712


Research Article

Role of Polymorphisms of FAM13A, PHLDB1, and CYP24A1 in Breast Cancer Risk

, 19(8): 579 - 588

Ying Wei*, Xiaolin Wang*, Zhe Zhang, Mingrui Xie, Yuyao Li, Hongxin Cao and Xinhan Zhao


DOI: 10.2174/1566524019666190619125109


Research Article

The Effect of Interleukin 38 on Inflammation-induced Corneal Neovascularization

, 19(8): 589 - 596

Jiangli Zhu, Jing Zhang, Yan Wang, Jianping Chen, Xiaopeng Li, Xiangling Liu, Eryan Kong, Shao B. Su* and Zhongjian Zhang*


DOI: 10.2174/1566524019666190627122655


Research Article



Research Article



Articles Ahead of Print

A COL4A5 Missense Variant in a Han-Chinese Family with X-linked Alport Syndrome


Yuan Wu, Yi Guo, Jinzhong Yuan, Hongbo Xu, Yong Chen, Hao Zhang, Mingyang Yuan, Hao Deng and Lamei Yuan*


DOI: 10.2174/1566524019666190906144214
View Abstract View on PubMed


Dynamic Changes of RFRP3/GPR147 in the Precocious Puberty Model Female Rats


Wen Sun, Suhuan Li, Zhanzhuang Tian, Yumin Shi, Jian Yu, Yanyan Sun and Yonghong Wang*


DOI: 10.2174/1566524019666190906142445
View Abstract View on PubMed







Characteristics of Natural Killer Cell Interaction with Trophoblast Cells During Pregnancy


Dmitry Olegovich Bazhenov*, Evgeniya Valerevna Khokhlova, Larisa Pavlovna Viazmina, Kseniya Nikolaevna Furaeva, Valentina Anatolievna Mikhailova, Nikolay Anatolievich Kostin, Sergey Alekseevich Selkov and Dmitry Igorevich Sokolov


DOI: 10.2174/1566524019666190808103227
View Abstract View on PubMed


High Glucose Affects the Cytotoxic Potential of Rapamycin, Metformin and Hydrogen Peroxide in Cultured Human Mesenchymal Stem Cells


Azam Roohi, Mahin Nikougoftar, Hamed Montazeri, Shadisadat Navabi, Fazel Shokri, Seyed Nasser Ostad and Mohammad Hossein Ghahremani*


DOI: 10.2174/1566524019666190722115842
View Abstract



Abstracts Ahead of Print

Involvement of Upregulated P53-Induced Death Domain Protein in Retinal Ganglion Cells Apoptosis after Optic Nerve Crush


Mingyuan Zhang, Lifei Chen, Fan Xu*, Li Jiang, Wenya Yan, Bibhav Kunwar, Fen Tang, Ke Yang, Chaolan Shen, Hui Huang, Jian Lv, Chen Qin, Xiaonian Wu, Siming Zeng, Min Li, Shan Zhong and Qi Chen


DOI: 10.2174/1566524019666190918160032
View Abstract




N-Acetyl Cysteine attenuates the sarcopenia and muscle apoptosis induced by chronic liver disease


Johanna Abrigo, Tabita Marín, Francisco Aguirre, Franco Tacchi, Cristian Vilos, Felipe Simon, Marco Arrese, Daniel Cabrera and Claudio Cabello-Verrugio*


DOI: 10.2174/1566524019666190917124636
View Abstract



Caspase-1 as Molecular Key in Cardiac Remodeling during Cardiorenal Syndrome Type 3 in the Murine Model


Mayra Trentin-Sonoda, Frayli Maltoni Fratoni, Carolina Victoria da Cruz Junho, Wellington Caio Silva, Karine Panico and Marcela Sorelli Carneiro-Ramos*


DOI: 10.2174/1566524019666190916153257
View Abstract


Frequency of Interleukins IL1ß/IL18 and Inflammasome NLRP1/NLRP3 Polymorphisms in Sickle Cell Anemia Patients and their Association with Severity Score


Emerson de Almeida, Sonia Rejane Frantz, Purim Cesar, Andrea Monteiro Tarragô, Lilyane de Amorim Xabregas, Nadja Pinto Garcia, Allyson Guimarães Costa, Erich Vinicius de Paula and Adriana Malheiro*


DOI: 10.2174/1566524019666190826143749
View Abstract


Candidate microRNAs in Malaria Infection Biomarkers: A Systematic Review


Gregorio Rangel, Nattawat Teerawattanapong, Supat Chamnanchanunt, Tsukuru Umemura, Anuwat Pinyachat and Surasak Wanram*


DOI: 10.2174/1566524019666190820124827
View Abstract


Published Contents

Editor's Choice




Altered Expression Patterns of the Sumoylation Enzymes E1, E2 and E3 Are Associated with Glucose Oxidase- and UVA-Induced Cataractogenesis

, 2018; 18(8): 542 - 549

Qian Nie, Ling Wang , Xiaodong Gong, Jia-Wen Xiang, Yuan Xiao, Jie Xie, Lan Yang, Huimin Chen, Yuwen Gan, Zhigang Chen and David Wan-Cheng Li*


DOI: 10.2174/1566524019666190111152324



Generation of a Primary Hyperoxaluria Type 1 Disease Model Via CRISPR/Cas9 System in Rats

, 2018; 18(7): 436 - 447

Rui Zheng, Xiaoliang Fang, Lei He, Yanjiao Shao, Nana Guo, Liren Wang, Mingyao Liu, Dali Li* and Hongquan Geng*


DOI: 10.2174/1566524019666181212092440



Digitoxin Suppresses Store Operated Calcium Entry by Modulating Phosphorylation and the Pore Region of Orai1

, 2018; 18(6): 392 - 399

Lijuan Zhou, Xiangxiang Chi, Yaping Zhu, Tian Zhang, Jindou Liu, Guolin Ma, Lian He, Shuce Zhang, Ping Gao, Yubin Zhou*, Jin Liu* and Youjun Wang


DOI: 10.2174/1566524018666181113111316



Hypoxia-Induced Caveolin-1 Expression Promotes Migration and Invasion of Tumor Cells

, 2018; 18(4): 199 - 206

J. Castillo Bennett, P. Silva, S. Martinez, V.A. Torres* and A.F.G. Quest*


DOI: 10.2174/1566524018666180926163218






Open Access Articles

Stem Cells as a Resource for Treatment of Infertility-related Diseases

, 2019; 19(8): 539 - 546

Jing Wang, Chi Liu, Masayuki Fujino, Guoqing Tong, Qinxiu Zhang, Xiao-Kang Li* and Hua Yan*




Attenuation of Cardiac Ischaemia-reperfusion Injury by Treatment with Hydrogen-rich Water

, 2019; 19(4): 294 - 302

Xiangzi Li, Liangtong Li, Xuanchen Liu, Jiawen Wu, Xiaoyu Sun, Zhilin Li, Yong-Jian Geng, Fulin Liu* and Yujuan Zhou*




Naoxintong Retards Atherosclerosis by Inhibiting Foam Cell Formation Through Activating Pparα Pathway

, 2018; 18(10): 698 - 710

Zeng Wang, Huairui Shi, Huan Zhao, Zhen Dong, Buchang Zhao, Xinyu Weng, Rongle Liu, Xiao Li, Kai Hu, Yunzeng Zou, Aijun Sun* and Junbo Ge *







Oxidative Stress in Cerebral Small Vessel Disease Dizziness Patients, Basally and After Polyphenol Compound Supplementation

, 2018; 18(3): 160 - 165

L. Ulivi, M. Maccarrone, N. Giannini, E. Ferrari, M.C. Caselli, V. Montano, L. Chico, A. Casani, E. Navari, N. Cerchiai, G. Siciliano, U. Bonuccelli and M. Mancuso*




Decreased Expression of TIM-3 on Th17 Cells Associated with Ophthalmopathy in Patients with Graves’ Disease

, 2018; 18(2): 83 - 90

J. Zhao, B. Lin, H. Deng, X. Zhi, Y. Li, Y. Liu, P.W. Bible, Q. Li, B. Xu, L. Wei, H. Yang* and D. Huang*




ZNF424 Induces Apoptosis and Inhibits Proliferation in Lung Carcinoma Cells

, 2018; 18(2): 109 - 115

W. Liu, W. Yuan, X. Li, J. Zhuang, X. Mo, G. Dai, Y. Wang, J. Chen, Y. Wan, Y. Li, X. Zhu, Y. Chen, S. Luo, Z. Jiang, Y. Shi, F. Chen, L. Cao, X. Ye, X. Fan*, P. Zhu*, K. Zhang* and X. Wu*




Decreased Expression of MYPT1 Contributes to Tumor Angiogenesis and Poor Patient Prognosis in Human Prostate Cancer

, 2018; 18(2): 100 - 108

Y. Liang, Y. Zhuo, Z. Lin, F. Jiang, Q. Dai, J. Lu, W. Dong, X. Zhu, Z. Han* and W. Zhong*






Role of Zebrafish fhl1A in Satellite Cell and Skeletal Muscle Development

, 2017; 17(9): 627 - 636

F. Chen, W. Yuan, X. Mo, J. Zhuang, Y. Wang, J. Chen, Z. Jiang, X. Zhu, Q. Zeng, Y. Wan, F. Li, Y. Shi, L. Cao, X. Fan, S. Luo, X. Ye, Y. Chen, G. Dai, J. Gao, X. Wang, H. Xie*, P. Zhu*, Y. Li* and X. Wu*




The bHLH Protein Nulp1 is Essential for Femur Development Via Acting as a Cofactor in Wnt Signaling in Drosophila

, 2017; 17(7): 509 - 517

Q. Zeng, Y. Wan, P. Zhu, M. Zhao, F. Jiang, J. Chen, M. Tang, X. Zhu, Y. Li, H. Zha, Y. Wang, M. Hu, X. Mo, Y. Zhang, Y. Chen, Y. Chen, X. Ye, R. Bodmer, K. Ocorr, Z. Jiang*, J. Zhuang*, W. Yuan* and X. Wu*






Most Cited Articles

Review Article

Role of HIF-1 in cancer progression: Novel insights. a review

, 2018; 18(6): 343-351.

Aldo Pezzuto* and Elisabetta Carico


DOI: 10.2174/1566524018666181109121849


Review Article

Advances in tumor targeted liposomes

, 2018; 18(1): 44-57.

A. Jain and S.K. Jain*


DOI: 10.2174/1566524018666180416101522


Research Article

Differential expression of sumoylation enzymes sae1, U BA2, UBC9, PIAS1 AND RanBP2 in major ocular tissues of mouse eye

, 2018; 18(6): 376-382.

Qian Nie*, Lan Yang*, Wenjie Qing*, Jie Xie, Xiaodong Gong, Huimin Chen, Yuwen Gan, Ling Wang, Jia-Wen Xiang, Yuan Xiao, Zhigang Chen and David Wan-Cheng Li*


DOI: 10.2174/1566524018666181116112208



Research Article

Decreased expression of TIM-3 on TH17 cells associated with ophthalmopathy in patients with graves’ disease

, 2018; 18(2): 83-90.

J. Zhao, B. Lin, H. Deng, X. Zhi, Y. Li, Y. Liu, P.W. Bible, Q. Li, B. Xu, L. Wei, H. Yang* and D. Huang*


DOI: 10.2174/1566524018666180705105753


Research Article

VEGFR2 and VEGF-C suppresses the epithelial-mesenchymal transition via yap in retinal pigment epithelial cells

, 2018; 18(5): 273-286.

Y. Du, Q. Chen, L. Huang, S. Wang, X. Yin, L. Zhou, Z. Ye, X. Ren, Y. Cai, X. Ding, H. Ouyang, X. Li* and R. Ju*


DOI: 10.2174/1566524018666181004115304


Research Article

Decreased expression of MYPT1 contributes to tumor angiogenesis and poor patient prognosis in human prostate cancer

, 2018; 18(2): 100-108.

Y. Liang, Y. Zhuo, Z. Lin, F. Jiang, Q. Dai, J. Lu, W. Dong, X. Zhu, Z. Han* and W. Zhong*


DOI: 10.2174/1566524018666180705111342



Research Article

Oxidative stress in cerebral small vessel disease dizziness patients, basally and after polyphenol compound supplementation

, 2018; 18(3): 160-165.

L. Ulivi, M. Maccarrone, N. Giannini, E. Ferrari, M.C. Caselli, V. Montano, L. Chico, A. Casani, E. Navari, N. Cerchiai, G. Siciliano, U. Bonuccelli and M. Mancuso*


DOI: 10.2174/1566524018666180720165055





Research Article

Naoxintong retards atherosclerosis by inhibiting foam cell formation through activating PPARα pathway

, 2018; 18(10): 698-710.

Zeng Wang, Huairui Shi, Huan Zhao, Zhen Dong, Buchang Zhao, Xinyu Weng, Rongle Liu, Xiao Li, Kai Hu, Yunzeng Zou, Aijun Sun* and Junbo Ge *


DOI: 10.2174/1566524019666190207143207


Research Article

The sumoylation modulated tumor suppressor p <sup>53</sup> regulates cell cycle checking genes to mediate lens differentiation

, 2018; 18(8): 556-565.

Xiangcheng Tang, Zhigang Chen, Mi Deng, Ling Wang, Qian Nie, Jia-Wen Xiang, Yuan Xiao, Lan Yang, Yizhi Liu* and David Wan-Cheng Li*


DOI: 10.2174/1566524019666190111154450


Research Article

Localization patterns of sumoylation enzymes e1, e2 and e3 in ocular cell lines predict their functional importance

, 2018; 18(8): 516-522.

Xiaodong Gong, Qian Nie, Yuan Xiao, Jia-Wen Xiang, Ling Wang, Fangyuan Liu, Jia-Ling Fu, Yunfei Liu, Lan Yang, Yuwen Gan, Huimin Chen, Zhongwen Luo, Ruili Qi, Zhigang Chen, Xiangcheng Tang and David Wan-Cheng Li*


DOI: 10.2174/1566524019666190112144436



Most Accessed Articles

Blood Flow Regulates Zebrafish Caudal Vein Plexus Angiogenesis by ERK5-klf2a-nos2b Signaling

, 2018; 18(1): 3-14.

X. Xie, T. Zhou, Y. Wang, H. Chen, D. Lei, L. Huang, Y. Wang, X. Jin, T. Sun, J. Tan, T. Yin, J. Huang, H. Gregersen and G. Wang*


DOI: 10.2174/1566524018666180322153432


Identifying the Potential Substrates of the Depalmitoylation Enzyme Acyl-protein Thioesterase 1

, 2019; 19(5): 364-375.

Huicong Liu, Peipei Yan, Junyan Ren, Can Wu, Wei Yuan, Muding Rao, Zhongjian Zhang* and Eryan Kong*


DOI: 10.2174/1566524019666190325143412






Negative Correlation Between Serum Levels of Homocysteine and Apolipoprotein M

, 2019; 19(2): 120-126.

J. Wei, Y. Yu, Y. Feng, J. Zhang, Q. Jiang, L. Zheng, X. Zhang, N. Xu and G. Luo*


DOI: 10.2174/1566524019666190308115624



Stew in its Own Juice: Protein Homeostasis Machinery Inhibition Reduces Cell Viability in Multiple Myeloma Cell Lines

, 2019; 19(2): 112-119.

Mariana B. de Oliveira, Luiz F.G. Sanson, Angela I.P. Eugenio, Rebecca S.S. Barbosa-Dantas and Gisele W.B. Colleoni*


DOI: 10.2174/1566524019666190305134441


Serotonin and Cancer: What Is the Link?

, 2015; 15(1): 62-77.

D. Sarrouilhe, J. Clarhaut, N. Defamie and M. Mesnil


DOI: 10.2174/1566524015666150114113411




Editors-in-Chief

David W. Li
State Key Laboratory of Ophthalmology
Zhongshan Ophthalmic Center
Sun Yat-sen University
Guangzhou
China

View Full Editorial Board
Andras Guttman
University of Pannonia
Veszprém
Hungary

Biography View Full Editorial Board

Journal History

Current Molecular Medicine was introduced in 2001 with the assistance of Dr. David W. Li, who is the current Editor-in-Chief serving since 2001.
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