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Current Molecular Medicine

Volume 19, 10 Issues, 2019
ISSN: 1875-5666 (Online)
ISSN: 1566-5240 (Print)
This journal supports open access

Ranking and Category

  • 84th of 136 in

    Medicine, Research & Experimental

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Aims & Scope

Current Molecular Medicine is an interdisciplinary journal focused on providing the readership with current and comprehensive reviews/ mini-reviews, original research articles, short communications/letters and drug clinical trial studies on fundamental molecular mechanisms of disease pathogenesis, the development of molecular-diagnosis and/or novel approaches to rational treatment. The reviews should be of significant interest to basic researchers and clinical investigators in molecular medicine. Periodically the journal invites guest editors to devote an issue on a basic research area that shows promise to advance our understanding of the molecular mechanism(s) of a disease or has potential for clinical applications.

Current Molecular Medicine

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Volume 19

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Number 10



Review Article



Review Article



Letter



Research Article

Effects of Follicular Helper T Cells and Inflammatory Cytokines on Myasthenia Gravis

, 19(10): 739 - 745

Lifang Wang, Yu Zhang, Mingqin Zhu, Jiachun Feng*, Jinming Han, Jie Zhu and Hui Deng*


DOI: 10.2174/1566524019666190827162615


Research Article



Research Article

A COL4A5 Missense Variant in a Han-Chinese Family with X-linked Alport Syndrome

, 19(10): 758 - 765

Yuan Wu, Yi Guo, Jinzhong Yuan, Hongbo Xu, Yong Chen, Hao Zhang, Mingyang Yuan, Hao Deng and Lamei Yuan*


DOI: 10.2174/1566524019666190906144214


Research Article

Dynamic Changes of RFRP3/GPR147 in the Precocious Puberty Model Female Rats

, 19(10): 766 - 775

Wen Sun, Suhuan Li, Zhanzhuang Tian, Yumin Shi, Jian Yu, Yanyan Sun and Yonghong Wang*


DOI: 10.2174/1566524019666190906142445


Research Article

Frequency of Interleukins IL1ß/IL18 and Inflammasome NLRP1/NLRP3 Polymorphisms in Sickle Cell Anemia Patients and their Association with Severity Score

, 19(10): 776 - 783

Emerson de Almeida, Sonia Rejane Frantz, Purim Cesar, Andrea Monteiro Tarragô, Lilyane de Amorim Xabregas, Nadja Pinto Garcia, Allyson Guimarães Costa, Erich Vinicius de Paula and Adriana Malheiro*


DOI: 10.2174/1566524019666190826143749


Articles Ahead of Print


Overexpression of Pygo2 Increases Differentiation of Human Umbilical Cord Mesenchymal Stem Cells into Cardiomyocyte-like Cells


Lei Yang, Shuoji Zhu, Yongqing Li, Jian Zhuang, Jimei Chen, Huanlei Huang, Yu Chen, Yulin Wen, Yao Wen, Huiming Guo, Xiongwei Fan, Wuzhou Yuan, Zhigang Jiang*, Yuequn Wang*, Xiushan Wu* and Ping Zhu*


DOI: 10.2174/1566524019666191017150416
View Abstract


IL1R2 Polymorphisms are Associated with an Increased Risk of Esophageal Cancer


Jianfeng Liu, Yonghui Yang, Haiyue Li, Yuanwei Liu, Yao Sun, Jiamin Wu, Zichao Xiong and Tianbo Jin*


DOI: 10.2174/1566524019666191025091204
View Abstract





Immunogenetics of Celiac Disease: A Focus on Arab countries


Nadin Younes, Salma Younes, Ola A. Alsharabasi, Mohamed E. El Zowalaty, Ibrahim Mustafa, Mohamed Jahromi, Shahab Uddin, Mariam Al-Nesf, Gianfranco Pintus and Hatem Zayed*


DOI: 10.2174/1566524019666191024104930
View Abstract View on PubMed


A Brief Overview of the Oral Delivery of Insulin as an Alternative to the Parenteral Delivery


Ana Macedo, Patrícia Filipe, Natália G. Thomé, João Vieira, Carolina Oliveira, Catarina Teodósio, Raquel Ferreira, Luís Roque and Pedro Fonte*


DOI: 10.2174/1566524019666191010095522
View Abstract


Relaxin and the Cardiovascular System: From Basic Science to Clinical Practice


Rafael Clara Martins, Mariana Pintalhão, Adelino Leite-Moreira and Paulo Castro-Chaves


DOI: 10.2174/1566524019666191023121607
View Abstract View on PubMed


TRIM45 Suppresses the Development of Non-small Cell Lung Cancer


Xiyang Peng, Yao Wen, Lagabaiyila Zha, Jian Zhuang, Li Lin, Xu Li, Yu Chen, Zhiqiang Liu, Shuangli Zhu, Jifeng Liang, Zuoqiong Zhou, Wuzhou Yuan, Yongqing Li, Yuequn Wang, Zhigang Jiang, Xiaoyang Mo, Yongqi Wan, Yan Shi, Ping Zhu, Lan Zheng*, Changfa Tang, Xiushan Wu and Xiongwei Fan


DOI: 10.2174/1566524019666191017143833
View Abstract


Published Contents

Editor's Choice


The Molecular Pathology of Eye Tumors: A 2019 Update Main Interests for Routine Clinical Practice

, 2019; 19(9): 632 - 664

Sacha Nahon-Esteve, Arnaud Martel, Célia Maschi, Jean-Pierre Caujolle, Stéphanie Baillif, Sandra Lassalle* and Paul Hofman*


DOI: 10.2174/1566524019666190726161044






Altered Expression Patterns of the Sumoylation Enzymes E1, E2 and E3 Are Associated with Glucose Oxidase- and UVA-Induced Cataractogenesis

, 2018; 18(8): 542 - 549

Qian Nie, Ling Wang , Xiaodong Gong, Jia-Wen Xiang, Yuan Xiao, Jie Xie, Lan Yang, Huimin Chen, Yuwen Gan, Zhigang Chen and David Wan-Cheng Li*


DOI: 10.2174/1566524019666190111152324



Generation of a Primary Hyperoxaluria Type 1 Disease Model Via CRISPR/Cas9 System in Rats

, 2018; 18(7): 436 - 447

Rui Zheng, Xiaoliang Fang, Lei He, Yanjiao Shao, Nana Guo, Liren Wang, Mingyao Liu, Dali Li* and Hongquan Geng*


DOI: 10.2174/1566524019666181212092440



Digitoxin Suppresses Store Operated Calcium Entry by Modulating Phosphorylation and the Pore Region of Orai1

, 2018; 18(6): 392 - 399

Lijuan Zhou, Xiangxiang Chi, Yaping Zhu, Tian Zhang, Jindou Liu, Guolin Ma, Lian He, Shuce Zhang, Ping Gao, Yubin Zhou*, Jin Liu* and Youjun Wang


DOI: 10.2174/1566524018666181113111316



Hypoxia-Induced Caveolin-1 Expression Promotes Migration and Invasion of Tumor Cells

, 2018; 18(4): 199 - 206

J. Castillo Bennett, P. Silva, S. Martinez, V.A. Torres* and A.F.G. Quest*


DOI: 10.2174/1566524018666180926163218




Open Access Articles

Stem Cells as a Resource for Treatment of Infertility-related Diseases

, 2019; 19(8): 539 - 546

Jing Wang, Chi Liu, Masayuki Fujino, Guoqing Tong, Qinxiu Zhang, Xiao-Kang Li* and Hua Yan*





Attenuation of Cardiac Ischaemia-reperfusion Injury by Treatment with Hydrogen-rich Water

, 2019; 19(4): 294 - 302

Xiangzi Li, Liangtong Li, Xuanchen Liu, Jiawen Wu, Xiaoyu Sun, Zhilin Li, Yong-Jian Geng, Fulin Liu* and Yujuan Zhou*




Naoxintong Retards Atherosclerosis by Inhibiting Foam Cell Formation Through Activating Pparα Pathway

, 2018; 18(10): 698 - 710

Zeng Wang, Huairui Shi, Huan Zhao, Zhen Dong, Buchang Zhao, Xinyu Weng, Rongle Liu, Xiao Li, Kai Hu, Yunzeng Zou, Aijun Sun* and Junbo Ge *







Oxidative Stress in Cerebral Small Vessel Disease Dizziness Patients, Basally and After Polyphenol Compound Supplementation

, 2018; 18(3): 160 - 165

L. Ulivi, M. Maccarrone, N. Giannini, E. Ferrari, M.C. Caselli, V. Montano, L. Chico, A. Casani, E. Navari, N. Cerchiai, G. Siciliano, U. Bonuccelli and M. Mancuso*




Decreased Expression of TIM-3 on Th17 Cells Associated with Ophthalmopathy in Patients with Graves’ Disease

, 2018; 18(2): 83 - 90

J. Zhao, B. Lin, H. Deng, X. Zhi, Y. Li, Y. Liu, P.W. Bible, Q. Li, B. Xu, L. Wei, H. Yang* and D. Huang*




ZNF424 Induces Apoptosis and Inhibits Proliferation in Lung Carcinoma Cells

, 2018; 18(2): 109 - 115

W. Liu, W. Yuan, X. Li, J. Zhuang, X. Mo, G. Dai, Y. Wang, J. Chen, Y. Wan, Y. Li, X. Zhu, Y. Chen, S. Luo, Z. Jiang, Y. Shi, F. Chen, L. Cao, X. Ye, X. Fan*, P. Zhu*, K. Zhang* and X. Wu*




Decreased Expression of MYPT1 Contributes to Tumor Angiogenesis and Poor Patient Prognosis in Human Prostate Cancer

, 2018; 18(2): 100 - 108

Y. Liang, Y. Zhuo, Z. Lin, F. Jiang, Q. Dai, J. Lu, W. Dong, X. Zhu, Z. Han* and W. Zhong*






Role of Zebrafish fhl1A in Satellite Cell and Skeletal Muscle Development

, 2017; 17(9): 627 - 636

F. Chen, W. Yuan, X. Mo, J. Zhuang, Y. Wang, J. Chen, Z. Jiang, X. Zhu, Q. Zeng, Y. Wan, F. Li, Y. Shi, L. Cao, X. Fan, S. Luo, X. Ye, Y. Chen, G. Dai, J. Gao, X. Wang, H. Xie*, P. Zhu*, Y. Li* and X. Wu*




The bHLH Protein Nulp1 is Essential for Femur Development Via Acting as a Cofactor in Wnt Signaling in Drosophila

, 2017; 17(7): 509 - 517

Q. Zeng, Y. Wan, P. Zhu, M. Zhao, F. Jiang, J. Chen, M. Tang, X. Zhu, Y. Li, H. Zha, Y. Wang, M. Hu, X. Mo, Y. Zhang, Y. Chen, Y. Chen, X. Ye, R. Bodmer, K. Ocorr, Z. Jiang*, J. Zhuang*, W. Yuan* and X. Wu*





Most Cited Articles

Review Article

Role of HIF-1 in cancer progression: Novel insights. a review

, 2018; 18(6): 343-351.

Aldo Pezzuto* and Elisabetta Carico


DOI: 10.2174/1566524018666181109121849


Review Article

Advances in tumor targeted liposomes

, 2018; 18(1): 44-57.

A. Jain and S.K. Jain*


DOI: 10.2174/1566524018666180416101522


Research Article

Differential expression of sumoylation enzymes sae1, U BA2, UBC9, PIAS1 AND RanBP2 in major ocular tissues of mouse eye

, 2018; 18(6): 376-382.

Qian Nie*, Lan Yang*, Wenjie Qing*, Jie Xie, Xiaodong Gong, Huimin Chen, Yuwen Gan, Ling Wang, Jia-Wen Xiang, Yuan Xiao, Zhigang Chen and David Wan-Cheng Li*


DOI: 10.2174/1566524018666181116112208



Research Article

Decreased expression of TIM-3 on TH17 cells associated with ophthalmopathy in patients with graves’ disease

, 2018; 18(2): 83-90.

J. Zhao, B. Lin, H. Deng, X. Zhi, Y. Li, Y. Liu, P.W. Bible, Q. Li, B. Xu, L. Wei, H. Yang* and D. Huang*


DOI: 10.2174/1566524018666180705105753


Research Article

Genetic alleles associated with SLE susceptibility and clinical manifestations in Hispanic patients from the Dominican Republic

, 2019; 19(3): 164-171.

Zheng Liu, Yangsheng Yu, Yinshi Yue, Michelene Hearth-Holmes, Persio David Lopez, Carmen Tineo, Glenny Paulino, Wei-Neng Fu*, Esthela Loyo* and Kaihong Su*


DOI: 10.2174/1566524019666190424130809


Research Article

A traditional chinese patent medicine ZQMT for neovascular age-related macular degeneration: A multicenter randomized clinical trial

, 2018; 18(9): 622-629.

M. Jin*, H. Dai, X. Zhang, Y. Wang, M. Han, H. Zhang, Y. Liu, Z. Wang, X. Gao, L. Li, X. Wen, Y. Liu, L. Wei* and Y. Chen*


DOI: 10.2174/1566524019666190107155311



Research Article

Potential therapeutic applications of MDA-9/syntenin-NF-κB-RKIP loop in human liver carcinoma

, 2018; 18(9): 630-639.

Monica Notarbartolo, Manuela Labbozzetta, Fanny Pojero, Natale D'Alessandro and Paola Poma*


DOI: 10.2174/1566524019666190104105043


Research Article

Sodium iodate-induced mouse model of age-related macular degeneration displayed altered expression patterns of sumoylation enzymes e1, e2 and e3

, 2018; 18(8): 550-555.

Qian Nie, Xiaodong Gong, Lili Gong, Lan Zhang, Xiangcheng Tang, Ling Wang, Fangyuan Liu, Jia-ling Fu, Jia-Wen Xiang, Yuan Xiao, Zhongwen Luo, Ruili Qi, Zhigang Chen, Yunfei Liu, Qian Sun, Wenjie Qing, Lan Yang, Jie Xie, Ming Zou, Yuwen Gan, Huimin Chen and David Wan-Cheng Li*


DOI: 10.2174/1566524019666190112101147



Research Article

VEGFR2 and VEGF-C suppresses the epithelial-mesenchymal transition via yap in retinal pigment epithelial cells

, 2018; 18(5): 273-286.

Y. Du, Q. Chen, L. Huang, S. Wang, X. Yin, L. Zhou, Z. Ye, X. Ren, Y. Cai, X. Ding, H. Ouyang, X. Li* and R. Ju*


DOI: 10.2174/1566524018666181004115304


Research Article

Decreased expression of MYPT1 contributes to tumor angiogenesis and poor patient prognosis in human prostate cancer

, 2018; 18(2): 100-108.

Y. Liang, Y. Zhuo, Z. Lin, F. Jiang, Q. Dai, J. Lu, W. Dong, X. Zhu, Z. Han* and W. Zhong*


DOI: 10.2174/1566524018666180705111342



Review Article

Imidazoline receptor agonists for managing hypertension may hold promise for treatment of intracerebral hemorrhage

, 2018; 18(4): 241-251.

J. Mahmoudi, A. Majdi, S. Lattanzi, M. Di Napoli, E.M. Bershad, C.M.P. Rodrigues and A.A. Divani*


DOI: 10.2174/1566524018666180926163712



Most Accessed Articles

Blood Flow Regulates Zebrafish Caudal Vein Plexus Angiogenesis by ERK5-klf2a-nos2b Signaling

, 2018; 18(1): 3-14.

X. Xie, T. Zhou, Y. Wang, H. Chen, D. Lei, L. Huang, Y. Wang, X. Jin, T. Sun, J. Tan, T. Yin, J. Huang, H. Gregersen and G. Wang*


DOI: 10.2174/1566524018666180322153432


Identifying the Potential Substrates of the Depalmitoylation Enzyme Acyl-protein Thioesterase 1

, 2019; 19(5): 364-375.

Huicong Liu, Peipei Yan, Junyan Ren, Can Wu, Wei Yuan, Muding Rao, Zhongjian Zhang* and Eryan Kong*


DOI: 10.2174/1566524019666190325143412





Serotonin and Cancer: What Is the Link?

, 2015; 15(1): 62-77.

D. Sarrouilhe, J. Clarhaut, N. Defamie and M. Mesnil


DOI: 10.2174/1566524015666150114113411


The Effect of Interleukin 38 on Inflammation-induced Corneal Neovascularization

, 2019; 19(8): 589-596.

Jiangli Zhu, Jing Zhang, Yan Wang, Jianping Chen, Xiaopeng Li, Xiangling Liu, Eryan Kong, Shao B. Su* and Zhongjian Zhang*


DOI: 10.2174/1566524019666190627122655



Inhibition of Experimental Age-Related Macular Degeneration by ZQMT in Mice

, 2019; 19(6): 434-442.

Liu Yang*, Huan Meng*, Dan Luo, Tingting Deng, Li Miao, Bin Zou, Xiaofei Ge, Xiao Hu, Yu Liu, Xifang Li, Xiuli Deng, Shixin Guo, Juanran Liang, Tingting Chen, Xiaofeng Wen, Jing Jing Li, Lai Wei and Ming Jin


DOI: 10.2174/1566524019666190425195706





Editors-in-Chief

David W. Li
State Key Laboratory of Ophthalmology
Zhongshan Ophthalmic Center
Sun Yat-sen University
Guangzhou
China

View Full Editorial Board
Andras Guttman
University of Pannonia
Veszprém
Hungary

Biography View Full Editorial Board

Journal History

Current Molecular Medicine was introduced in 2001 with the assistance of Dr. David W. Li, who is the current Editor-in-Chief serving since 2001.
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Scopus CiteScore Metrics: 1.69

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