Contents

Current Medicinal Chemistry, Volume 8 - Number 3

Preface

, 8(3): i

Robert A. Greenwald and Lorne M. Golub


DOI: 10.2174/0929867013373688




Biologic Properties of Non-Antibiotic, Chemically Modified Tetracyclines (CMTs): A Structured, Annotated Bibliography

, 8(3): 237 - 242

Robert A. Greenwald and Lorne M. Golub


DOI: 10.2174/0929867013373624




The Lipophilicity, Pharmacokinetics, and Cellular Uptake of Different Chemically-Modified Tetracyclines (CMTs)

, 8(3): 243 - 252

Y. Liu, S. N. Ramamurthy, J. Marecek, M. H. Lee, L. J. Chen, E. M. Ryan, R. B. Rifkin and M. L. Golub


DOI: 10.2174/0929867013373525




Biodistribution of Radiolabeled [ 3 H] CMT-3 in Rats

, 8(3): 253 - 256

J. Chen, M. Bookbinder, M. E. Ryan, L. M. Golub, R. Ashley and N. S. Ramamurthy


DOI: 10.2174/0929867013373615




CMT-3, a Non-antimicrobial Tetracycline (TC), Inhibits MT1-MMP Activity: Relevance to Cancer

, 8(3): 257 - 260

M. H. Lee, M. L. Golub, J. Cao, O. Teronen, M. Laitinen, T. Salo, S. Zucker and T. Sorsa


DOI: 10.2174/0929867013373660




Inhibition of Tumor Cell Invasiveness by Chemically Modified Tetracyclines

, 8(3): 261 - 270

Y. Gu, M. H. Lee, J. E. Roemer, L. Musacchia, M. L. Golub and R. S. Simon


DOI: 10.2174/0929867013373642




Cytotoxic Activity and Inhibition of Tumor Cell Invasion by Derivatives of a Chemically Modified Tetracycline CMT-3 (COL-3)

, 8(3): 271 - 279

Bal L. Lokeshwar, Eva Escatel and Baoqian Zhu


DOI: 10.2174/0929867013373516




Wound Healing in Ovariectomized Rats Effects of Chemically Modified Tetracycline (CMT-8) and Estrogen on Matrix Metalloproteinases -8, -13 and Type I Collagen Expression

, 8(3): 281 - 294

Emma Pirila, Nungavarm Ramamurthy, Paivi Maisi, Steve McClain, Allan Kucine, Jaana Wahlgren, Lorne M Golub, Tuula Salo and Timo Sorsa


DOI: 10.2174/0929867013373552




A Combination of Subtherapeutic Doses of Chemically Modified Doxycycline (CMT-8) and a Bisphosphonate (Clodronate) Inhibits Bone Loss in the Ovariectomized Rat A Dynamic Histomorphometric and Gene Expression Study

, 8(3): 295 - 303

N. S. Ramamurthy, S. Bain, C. T. Liang, J. Barnes, A. Llavaneras, Y. Liu, D. Puerner, M. J. Strachan and L. M. Golub


DOI: 10.2174/0929867013373534




Excessive Matrix Metalloproteinase Activity in Diabetes: Inhibition by Tetracycline Analogues with Zinc Reactivity

, 8(3): 305 - 316

Maria E. Ryan, Adil Usman, N. S. Ramamurthy, Lorne M. Golub and Robert A. Greenwald


DOI: 10.2174/0929867013373598




A Role for the Anti-Inflammatory Properties of Tetracyclines in the Prevention of Acute Lung Injury

, 8(3): 317 - 325

G. F. Nieman and B. R. Zerler


DOI: 10.2174/0929867013373570




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