Contents

Current Medicinal Chemistry, Volume 21 - Number 15

Editorial (Thematic Issue: Drug Discovery for Infectious Agents Causing Neglected Diseases)

, 21(15): 1667

Ariel M. Silber, Claudio A. Pereira and Carsten Wrenger


DOI: 10.2174/0929867321666131201144041




Targeting Protozoan Parasite Metabolism: Glycolytic Enzymes in the Therapeutic Crosshairs

, 21(15): 1668 - 1678

M.T. Harris, W.G. Mitchell and J.C. Morris


DOI: 10.2174/09298673113206660286




Glycosomal Targets for Anti-Trypanosomatid Drug Discovery

, 21(15): 1679 - 1706

X. Barros-Alvarez, M. Gualdron-Lopez, H. Acosta, A.J. Caceres, M.A.S. Graminha, P.A.M. Michels, J.L. Concepcion and W. Quinones


DOI: 10.2174/09298673113209990139




Metabolite Transporters in Trypanosomatid Parasites: Promising Therapeutic Targets But… How to Deal with Them?

, 21(15): 1707 - 1712

C.A. Pereira, M. Saye, C. Wrenger and M.R. Miranda


DOI: 10.2174/09298673113209990228




Drug Development Against Sleeping Sickness: Old Wine in New Bottles?

, 21(15): 1713 - 1727

J. Stein, S. Mogk, C.N. Mudogo, B.P. Sommer, M. Scholze, A. Meiwes, M. Huber, A. Gray and M. Duszenko


DOI: 10.2174/0929867320666131119121636




The Redox Systems of Plasmodium falciparum and Plasmodium vivax: Comparison, In silico Analyses and Inhibitor Studies

, 21(15): 1728 - 1756

F. Mohring, J. Pretzel, E. Jortzik and K. Becker


DOI: 10.2174/0929867321666131201144612




Key Proteins in the Polyamine-Trypanothione Pathway as Drug Targets Against Trypanosoma cruzi

, 21(15): 1757 - 1771

J.D. Maya, C.O. Salas, B. Aguilera-Venegas, M.V. Diaz and R. Lopez-Munoz


DOI: 10.2174/0929867320666131119122145




Biological Implications of Selenium and its Role in Trypanosomiasis Treatment

, 21(15): 1772 - 1780

M.T.A. da Silva, I. Silva-Jardim and O.H. Thiemann


DOI: 10.2174/0929867320666131119121108




Transition-State-Guided Drug Design for Treatment of Parasitic Neglected Tropical Diseases

, 21(15): 1781 - 1793

A.S. Murkin and M.M. Moynihan


DOI: 10.2174/09298673113206660285




Protective Mechanisms of Helminths Against Reactive Oxygen Species are Highly Promising Drug Targets

, 21(15): 1794 - 1808

Markus Perbandt, Dieudonne Ndjonka and Eva Liebau


DOI: 10.2174/0929867320666131119122907




MRSA Infections: From Classical Treatment to Suicide Drugs

, 21(15): 1809 - 1819

Julia Drebes, Madeleine Kunz, Claudio A. Pereira, Christian Betzel and Carsten Wrenger


DOI: 10.2174/0929867320666131119122520




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