Contents

Current Medicinal Chemistry, Volume 19 - Number 8

Editorial [Hot Topic: Recent Achievements on G-Protein Coupled Receptors (Guest Editor: Slawomir Filipek)]

, 19(8): 1089

Slawomir Filipek


DOI: 10.2174/092986712799320501




Action of Molecular Switches in GPCRs - Theoretical and Experimental Studies

, 19(8): 1090 - 1109

B. Trzaskowski, D. Latek, S. Yuan, U. Ghoshdastider, A. Debinski and S. Filipek


DOI: 10.2174/092986712799320556




Evolution of Class A G-Protein-Coupled Receptors: Implications for Molecular Modeling

, 19(8): 1110 - 1118

M. Chabbert, H. Castel, J. Pele, J. Deville, R. Legendre and P. Rodien


DOI: 10.2174/092986712799320600




Crosstalk within GPCR Heteromers in Schizophrenia and Parkinsons Disease: Physical or Just Functional?

, 19(8): 1119 - 1134

R. Guixa-Gonzalez, A. Bruno, M. Marti-Solano and J. Selent


DOI: 10.2174/092986712799320574




A Closer Look into G Protein Coupled Receptor Activation: X-Ray Crystallography and Long-Scale Molecular Dynamics Simulations

, 19(8): 1135 - 1145

S. Vanni and U. Rothlisberger


DOI: 10.2174/092986712799320493




Ensemble of G Protein-Coupled Receptor Active States

, 19(8): 1146 - 1154

P. S.-H. Park


DOI: 10.2174/092986712799320619




Recent Progress in Understanding of Structure, Ligand Interactions and the Mechanism of Activation of the β 2-Adrenergic Receptor

, 19(8): 1155 - 1163

M. Kolinski, A. Plazinska and K. Jozwiak


DOI: 10.2174/092986712799320547




RAS/RAF/MEK Inhibitors in Oncology

, 19(8): 1164 - 1176

M. Broggini


DOI: 10.2174/092986712799320510




Diketoacid Inhibitors of HIV-1 Integrase: From L-708,906 to Raltegravir and Beyond

, 19(8): 1177 - 1192

K. D. Beare, M. J. Coster and P. J. Rutledge


DOI: 10.2174/092986712799320565




Adiponectin and Cardiovascular Disease: Mechanisms and New Therapeutic Approaches

, 19(8): 1193 - 1209

G. Siasos, D. Tousoulis, C. Kollia, E. Oikonomou, Z. Siasou, C. Stefanadis and A. G. Papavassiliou


DOI: 10.2174/092986712799320583




New Developments in the Diagnosis and Management of Resistant Hypertension

, 19(8): 1210 - 1218

A. de la Sierra


DOI: 10.2174/092986712799320592




Molecular Pathways Involved in the Early and Late Damage Induced by Testis Ischemia: Evidence for a Rational Pharmacological Modulation

, 19(8): 1219 - 1224

L. Minutoli


DOI: 10.2174/092986712799320538




Advances in the Research of β-Ketoacyl-ACP Synthase III (FabH) Inhibitors

, 19(8): 1225 - 1237

H. -J. Zhang, Z. -L. Li and H. -L. Zhu


DOI: 10.2174/092986712799320484




Targeting DNA Topoisomerase I with Non-Camptothecin Poisons

, 19(8): 1238 - 1257

G. L. Beretta, V. Zuco, P. Perego and N. Zaffaroni


DOI: 10.2174/092986712799320529




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