Contents

Current Medicinal Chemistry, Volume 19 - Number 33

Editorial

Editorial [Hot Topic: Role of Reactive Oxygen Species in Cocaine-Induced Target Organ Dysfunction. Mechanisms of Action and Therapeutic Perspectives]

, 19(33): 5595 - 5596

Vittorio Fineschi


DOI: 10.2174/092986712803988875




Neuropathological Alterations in Cocaine Abuse

, 19(33): 5597 - 5600

A. Buttner


DOI: 10.2174/092986712803988947




Contribution of Oxidative Metabolism to Cocaine-Induced Liver and Kidney Damage

, 19(33): 5601 - 5606

M.J. Valente, F. Carvalho, M.d.L. Bastos, P.G. de Pinho and M. Carvalho


DOI: 10.2174/092986712803988938




Interstitial Lung Damage Due to Cocaine Abuse: Pathogenesis, Pharmacogenomics and Therapy

, 19(33): 5607 - 5611

M. Drent, P. Wijnen and A. Bast


DOI: 10.2174/092986712803988901




Diagnosis and Consequences of Cocaine Addiction

, 19(33): 5612 - 5618

L. Karila, A. Petit, W. Lowenstein and M. Reynaud


DOI: 10.2174/092986712803988839




Role of Oxidative Stress in Cocaine-Induced Cardiotoxicity and Cocaine-Related Death

, 19(33): 5619 - 5623

D. Cerretani, V. Fineschi, S. Bello, I. Riezzo, E. Turillazzi and M. Neri


DOI: 10.2174/092986712803988785




Side Effects of Cocaine Abuse: Multiorgan Toxicity and Pathological Consequences

, 19(33): 5624 - 5646

I. Riezzo, C. Fiore, D. De Carlo, N. Pascale, M. Neri, E. Turillazzi and V. Fineschi


DOI: 10.2174/092986712803988893




Data Available on the Extent of Cocaine Use and Dependence: Biochemistry, Pharmacologic Effects and Global Burden of Disease of Cocaine Abusers

, 19(33): 5647 - 5657

C. Pomara, T. Cassano, S. D'Errico, S. Bello, A.D. Romano, I. Riezzo and G. Serviddio


DOI: 10.2174/092986712803988811




Toxicokinetics of Cocaine and Metabolites: The Forensic Toxicological Approach

, 19(33): 5658 - 5663

F. Bortolotti, R. Gottardo, J. Pascali and F. Tagliaro


DOI: 10.2174/092986712803988794




Cardiovascular Effects of Cocaine: Cellular, Ionic and Molecular Mechanisms

, 19(33): 5664 - 5676

E. Turillazzi, S. Bello, M. Neri, C. Pomara, I. Riezzo and V. Fineschi


DOI: 10.2174/092986712803988848




Cocaine Toxicity and Hepatic Oxidative Stress

, 19(33): 5677 - 5682

V. Vitcheva


DOI: 10.2174/092986712803988929




Medicinal Chemistry of Drugs with Active Metabolites (N-, O-, and S-desalkylation and Some Specific Oxidative Alterations)

, 19(33): 5683 - 5704

N. Ram, H. Kalasz, E. Adeghate, F. Darvas, F. Hashemi and K. Tekes


DOI: 10.2174/092986712803988820




Natural Product MDM2 Inhibitors: Anticancer Activity and Mechanisms of Action

, 19(33): 5705 - 5725

J.-J. Qin, S. Nag, S. Voruganti, W. Wang and R. Zhang


DOI: 10.2174/092986712803988910




Yersinia pestis and Approaches to Targeting its Outer Protein H Protein-Tyrosine Phosphatase (YopH)

, 19(33): 5726 - 5734

M. Bahta and T.R. Burke


DOI: 10.2174/092986712803988866




Signal Transduction Pathways of the Epidermal Growth Factor Receptor in Colorectal Cancer and their Inhibition by Small Molecules

, 19(33): 5735 - 5744

T. Efferth


DOI: 10.2174/092986712803988884




Chemistry and Pharmacology of Imexon and Related Cyanoaziridines

, 19(33): 5745 - 5753

W.A. Remers and R.T. Dorr


DOI: 10.2174/092986712803988802




Hepatocyte-Targeted Delivery Using pH-Sensitive Liposomes Loaded with Lactosylnorcantharidin Phospholipid Complex: Preparation, Characterization, and Therapeutic Evaluation In Vivo and In Vitro

, 19(33): 5754 - 5763

Z. Qiao-ling, Z. Yi, G. Min, Y. Di-jia, Z. Xiao-feng, L. Yang, X. Jing-yu, W. Ying, G. Zong-lin, X. Kong-lang, Z. Ai-jun, C. Wei-liang, S. Lin-sen, Z. Xue-nong and Z. Qiang


DOI: 10.2174/092986712803988857




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