Contents

Current Medicinal Chemistry, Volume 19 - Number 23

EDITORIAL (Hot Topic: Cancer Chemoresistance and DNA Repair)

, 19(23): 3857

Simone Mocellin


DOI: 10.2174/092986712802002545




Synthetic Lethality to Overcome Cancer Drug Resistance

, 19(23): 3858 - 3873

L. Porcelli, A. E. Quatrale, P. Mantuano, N. Silvestris, A. E. Brunetti, H. Calvert, A. Paradiso and A. Azzariti


DOI: 10.2174/092986712802002563




DNA Repair and Resistance to Topoisomerase I Inhibitors: Mechanisms, Biomarkers and Therapeutic Targets

, 19(23): 3874 - 3885

M. Alagoz, D. C. Gilbert, S. El-Khamisy and A. J. Chalmers


DOI: 10.2174/092986712802002590




Strategies to Improve the Killing of Tumors Using Temozolomide: Targeting the DNA Repair Protein MGMT

, 19(23): 3886 - 3892

G. Jiang, L. -T. Li, Y. Xin, L. Zhang, Y. -Q. Liu and J. -N. Zheng


DOI: 10.2174/092986712802002446




Circumventing Melanoma Chemoresistance by Targeting DNA Repair

, 19(23): 3893 - 3899

S. Mocellin, L Bertazza, C. Benna and P. Pilati


DOI: 10.2174/092986712802002509




Cancer Resistance to Type II Topoisomerase Inhibitors

, 19(23): 3900 - 3906

P. Pilati, D. Nitti and S. Mocellin


DOI: 10.2174/092986712802002473




Role of PARP Inhibitors in Cancer Biology and Therapy

, 19(23): 3907 - 3921

D. Davar, J. H. Beumer, L. Hamieh and H. Tawbi


DOI: 10.2174/092986712802002464




Base Excision Repair: Contribution to Tumorigenesis and Target in Anticancer Treatment Paradigms

, 19(23): 3922 - 3936

J. L. Illuzzi and D. M. Wilson III


DOI: 10.2174/092986712802002581




Polo-Like Kinases Inhibitors

, 19(23): 3937 - 3948

L. Garuti, M. Roberti and G. Bottegoni


DOI: 10.2174/092986712802002455




Coinage Metal Complexes Against Breast Cancer

, 19(23): 3949 - 3956

B. Biersack, A. Ahmad, F. H. Sarkar and R. Schobert


DOI: 10.2174/092986712802002482




Subtype-Selective Dopamine Receptor Radioligands for PET Imaging: Current Status and Recent Developments

, 19(23): 3957 - 3966

A. Banerjee and O. Prante


DOI: 10.2174/092986712802002518




Palladacycles as Antimicrobial Agents

, 19(23): 3967 - 3981

A. -S.S.H. Elgazwy, N. S.M. Ismail, S. R. Atta-Allah, M. T. Sarg, D. H.S. Soliman, M. Y. Zaki and M. A. Elgamas


DOI: 10.2174/092986712802002527




Recent Advances in Non-Peptidomimetic Dipeptidyl Peptidase 4 Inhibitors: Medicinal Chemistry and Preclinical Aspects

, 19(23): 3982 - 3999

Y. Liu, Y. Hu and T. Liu


DOI: 10.2174/092986712802002491




Glutathione-Related Factors and Oxidative Stress in Autism, A Review

, 19(23): 4000 - 4005

A. Ghanizadeh, S. Akhondzadeh, M. Hormozi, A. Makarem, M. Abotorabi-Zarchi and A. Firoozabadi


DOI: 10.2174/092986712802002572




Anti-Inflammatory Effect of 3,4-DHPEA-EDA [2-(3,4 -Hydroxyphenyl) ethyl (3S, 4E)- 4-Formyl-3-(2-Oxoethyl)Hex-4-Enoate] on Primary Human Vascular Endothelial Cells

, 19(23): 4006 - 4013

G. Sindona, A. Caruso, A. Cozza, S. Fiorentini, B. Lorusso, E. Marini, M. Nardi, A. Procopio and S. Zicari


DOI: 10.2174/092986712802002536




AG490 Promotes HIF-1α Accumulation by Inhibiting Its Hydroxylation

, 19(23): 4014 - 4023

R. Fernandez-Sanchez, S. Berzal, Maria-Dolores Sanchez-Nino, F. Neria, S. Goncalves, O. Calabia, A. Tejedor, M. J. Calzada, C. Caramelo, J. J.P. Deudero and A. Ortiz


DOI: 10.2174/092986712802002554




Insight into the Structural Determinants of Imidazole Scaffold-Based Derivatives as P38 MAP Kinase Inhibitors by Computational Explorations

, 19(23): 4024 - 4037

C. Huang, Y. Li, H. Ren, J. Wang, L. Shao, S. Zhang, G. Li and L. Yang


DOI: 10.2174/092986712802002608




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