Contents

Current Medicinal Chemistry, Volume 19 - Number 15

EDITORIAL [Hot Topic: Transthyretin: A Small Protein in the Big World of Amyloidoses (Guest Editors: Adriano Martinelli and Gabriella Ortore)]

, 19(15): 2303

Adriano Martinelli and Gabriella Ortore


DOI: 10.2174/092986712800269263




Transthyretin Deposition in Familial Amyloidotic Polyneuropathy

, 19(15): 2304 - 2311

M. J. Saraiva, J. Magalhaes, N. Ferreira and M. R. Almeida


DOI: 10.2174/092986712800269236




Diagnosis and Therapeutic Approaches to Transthyretin Amyloidosis

, 19(15): 2312 - 2323

Y. Ando and M. Ueda


DOI: 10.2174/092986712800269317




Nearly 200 X-Ray Crystal Structures of Transthyretin: What Do They Tell Us About This Protein and the Design of Drugs for TTR Amyloidoses?

, 19(15): 2324 - 2342

S. K. Palaninathan


DOI: 10.2174/092986712800269335




Methods to Evaluate the Inhibition of TTR Fibrillogenesis Induced by Small Ligands

, 19(15): 2343 - 2355

G. Arsequell and A. Planas


DOI: 10.2174/092986712800269281




TTR Fibril Formation Inhibitors: Is there a SAR?

, 19(15): 2356 - 2379

S. Nencetti and E. Orlandini


DOI: 10.2174/092986712800269326




Computational Studies on Transthyretin

, 19(15): 2380 - 2387

G. Ortore and A. Martinelli


DOI: 10.2174/092986712800269344




Supramolecular Approaches for Drug Development

, 19(15): 2388 - 2398

K. Kawakami, M. Ebara, H. Izawa, N. M. Sanchez-Ballester, J. P. Hill and K. Ariga


DOI: 10.2174/092986712800269254




CuAAC Click Chemistry Accelerates the Discovery of Novel Chemical Scaffolds as Promising Protein Tyrosine Phosphatases Inhibitors

, 19(15): 2399 - 2405

X. -P. He, J. Xie, Y. Tang, J. Li and G. -R. Chen


DOI: 10.2174/092986712800269245




Role of microRNAs in Gynecological Pathology

, 19(15): 2406 - 2413

J. Gilabert-Estelles, A. Braza-Boils, L. A. Ramon, E. Zorio, P. Medina, F. Espana and A. Estelles


DOI: 10.2174/092986712800269362




Sirtuin Modulators: Mechanisms and Potential Clinical Implications

, 19(15): 2414 - 2441

S. Sanchez-Fidalgo, I. Villegas, M. Sanchez-Hidalgo and C. Alarcon de la Lastra


DOI: 10.2174/092986712800269272




Recent Advances in the Development of 14-Alkoxy Substituted Morphinans as Potent and Safer Opioid Analgesics

, 19(15): 2442 - 2457

M. Spetea and H. Schmidhammer


DOI: 10.2174/092986712800269308




Syntheses and In-Vitro Evaluation of Novel Adamantane Based γ-Secretase Inhibitors

, 19(15): 2458 - 2471

A. O. Adeniji, R. M. Wells and A. Adejare


DOI: 10.2174/092986712800269353




An Artificial Neural Network Model for Predicting the Subcellular Localization of Photosensitisers for Photodynamic Therapy of Solid Tumours

, 19(15): 2472 - 2482

R. Tejedor-Estrada, S. Nonell, J. Teixido, M. L. Sagrista, M. Mora, A. Villanueva, M. Canete and J. C. Stockert


DOI: 10.2174/092986712800269290




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