Contents

Current Medicinal Chemistry, Volume 19 - Number 1

Foreword by the Editors

, 19(1): 1

Atta-ur-Rahman and William J. Hoekstra


DOI: 10.2174/092986712803414114




Editorial [Hot Topic: Novel Physiological and Pharmacological Avenues in the Mechanism of Gastrointestinal Integrity, Protection and Ulcer Healing (Guest Editors: Thomas Brzozowski)]

, 19(1): 2 - 3

Thomas Brzozowski


DOI: 10.2174/092986712803414024




The Mechanisms of Gastric Mucosal Injury: Focus on Microvascular Endothelium as a Key Target

, 19(1): 4 - 15

A. S. Tarnawski, A. Ahluwalia and M. K. Jones


DOI: 10.2174/092986712803414079




Molecular Mechanisms of Epithelial Regeneration and Neovascularization During Healing of Gastric and Esophageal Ulcers

, 19(1): 16 - 27

A. S. Tarnawski and A. Ahluwalia


DOI: 10.2174/092986712803414088




Recent Advances in Gut Nutrient Chemosensing

, 19(1): 28 - 34

C. A. Nguyen, Y. Akiba and J. D. Kaunitz


DOI: 10.2174/092986712803414033




Brainstem Neuropeptides and Vagal Protection of the Gastric Mucosal Against Injury: Role of Prostaglandins, Nitric Oxide and Calcitonin-Gene Related Peptide in Capsaicin Afferents

, 19(1): 35 - 42

Y. Tache


DOI: 10.2174/092986712803414097




Gas Mediators Involved in Modulating Duodenal HCO3- Secretion

, 19(1): 43 - 54

K. Takeuchi, E. Aihara, M. Kimura, K. Dogishi, T. Hara and S. Hayashi


DOI: 10.2174/092986712803413962




Novel Concept in the Mechanism of Injury and Protection of Gastric Mucosa: Role of Renin-Angiotensin System and Active Metabolites of Angiotensin

, 19(1): 55 - 62

T. Brzozowski, A. Ptak-Belowska, S. Kwiecien, G. Krzysiek-Maczka, M. Strzalka, D. Drozdowicz, R. Pajdo, R. Olszanecki, R. Korbut, S. J. Konturek and W. W. Pawlik


DOI: 10.2174/092986712803413953




Effects of Cigarette Smoke and its Active Components on Ulcer Formation and Healing in the Gastrointestinal Mucosa

, 19(1): 63 - 69

L. Zhang, J. W. Ren, C. C.M. Wong, W. K.K. Wu, S. X. Ren, J. Shen, R. L.Y. Chan and C. H. Cho


DOI: 10.2174/092986712803413926




Therapeutic Potential of Carbon Monoxide (CO) for Intestinal Inflammation

, 19(1): 70 - 76

Y. Naito, K. Uchiyama, T. Takagi and T. Yoshikawa


DOI: 10.2174/092986712803413935




Small Intestinal Injury Caused by NSAIDs/Aspirin: Finding New from Old

, 19(1): 77 - 81

T. Arakawa, T. Watanabe, T. Tanigawa, K. Tominaga, K. Otani, Y. Nadatani and Y. Fujiwara


DOI: 10.2174/092986712803414105




Management of NSAID/Aspirin-Induced Small Intestinal Damage by GI-Sparing NSAIDs, Anti-Ulcer Drugs and Food Constituents

, 19(1): 82 - 89

H. Satoh and K. Takeuchi


DOI: 10.2174/092986712803413980




Critical Role of Hypoxia Sensor - HIF-1α in VEGF Gene Activation. Implications for Angiogenesis and Tissue Injury Healing

, 19(1): 90 - 97

A. Ahluwalia and A. S. Tarnawski


DOI: 10.2174/092986712803413944




The ECL Cell: Relay Station for Gastric Integrity

, 19(1): 98 - 108

C. -M. Zhao and D. Chen


DOI: 10.2174/092986712803414060




Nutraceuticals for Protection and Healing of Gastrointestinal Mucosa

, 19(1): 109 - 117

M. Romano, P. Vitaglione, S. Sellitto and G. D'Argenio


DOI: 10.2174/092986712803414042




Protective and Therapeutic Effects of Ghrelin in the Gut

, 19(1): 118 - 125

Z. Warzecha and A. Dembinski


DOI: 10.2174/092986712803414051




Focus on Ulcerative Colitis: Stable Gastric Pentadecapeptide BPC 157

, 19(1): 126 - 132

P. Sikiric, S. Seiwerth, R. Rucman, B. Turkovic, D. S. Rokotov, L. Brcic, M. Sever, R. Klicek, B. Radic, D. Drmic, S. Ilic, D. Kolenc, V. Stambolija, Z. Zoricic, H. Vrcic and B. Sebecic


DOI: 10.2174/092986712803414015




MicroRNAs and Chronic Inflammation Contribution to Gastrointestinal Integrity

, 19(1): 133 - 136

A. Ptak-Belowska, A. Targosz and T. Brzozowski


DOI: 10.2174/092986712803413999




The Role of Methylglyoxal-Modified Proteins in Gastric Ulcer Healing

, 19(1): 137 - 144

T. Takagi, Y. Naito, T. Oya-Ito and T. Yoshikawa


DOI: 10.2174/092986712803413971




The Inhibition of Cell Proliferation Using Silencing of N-Cadherin Gene by siRNA Process in Human Melanoma Cell Lines

, 19(1): 145 - 151

D. Ciolczyk-Wierzbicka, D. Gil and P. Laidler


DOI: 10.2174/092986712803414006




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