Contents

Current Medicinal Chemistry, Volume 18 - Number 17

Editorial [Hot Topic:Methodologies and Applied Strategies in the Rational Drug Design (Guest Editor: T. Mavromoustakos)]

, 18(17): 2516

T. Mavromoustakos


DOI: 10.2174/092986711795933650




Strategies in the Rational Drug Design

, 18(17): 2517 - 2530

T. Mavromoustakos, S. Durdagi, C. Koukoulitsa, M. Simcic, M. G. Papadopoulos, M. Hodoscek and S. Golic Grdadolnik


DOI: 10.2174/092986711795933731




Multitarget Cardiovascular Drugs

, 18(17): 2531 - 2542

U. Trstenjak and D. Kikelj


DOI: 10.2174/092986711795933768




Pharmacophore Modelling: A Forty Year Old Approach and its Modern Synergies

, 18(17): 2543 - 2553

F. Caporuscio and A. Tafi


DOI: 10.2174/092986711795933669




Inhibitors of Aldo-Keto Reductases AKR1C1-AKR1C4

, 18(17): 2554 - 2565

P. Brozic, S. Turk, T. Lanisnik Rizner and S. Gobec


DOI: 10.2174/092986711795933713




The Application of Rational Design on Phospholipase A2 Inhibitors

, 18(17): 2566 - 2582

V. D. Mouchlis, E. Barbayianni, T. M. Mavromoustakos and G. Kokotos


DOI: 10.2174/092986711795933678




Members of CRF Family and their Receptors: From Past to Future

, 18(17): 2583 - 2600

G. Liapakis, M. Venihaki, A. Margioris, D. Grigoriadis and K. Gkountelias


DOI: 10.2174/092986711795933704




Atomistic Models for Free Energy Evaluation of Drug Binding to Membrane Proteins

, 18(17): 2601 - 2611

S. Durdagi, C. Zhao, J. E. Cuervo and S. Y. Noskov


DOI: 10.2174/092986711795933641




Ligand and Structure Based Virtual Screening Strategies for Hit-Finding and Optimization of Hepatitis C Virus (HCV) Inhibitors

, 18(17): 2612 - 2619

G. Melagraki and A. Afantitis


DOI: 10.2174/092986711795933759




From Structure – Based to Knowledge – Based Drug Design Through X-Ray Protein Crystallography: Sketching Glycogen Phosphorylase Binding Sites

, 18(17): 2620 - 2629

E. D. Chrysina, A. Chajistamatiou and M. Chegkazi


DOI: 10.2174/092986711795933632




Aluminum Vaccine Adjuvants: Are they Safe?

, 18(17): 2630 - 2637

L. Tomljenovic and C. A. Shaw


DOI: 10.2174/092986711795933740




Amphiphilic Polysaccharide-Hydrophobicized Graft Polymeric Micelles for Drug Delivery Nanosystems

, 18(17): 2638 - 2648

Y. Liu, J. Sun, P. Zhang and Z. He


DOI: 10.2174/092986711795933696




Retroviral Restriction Factors TRIM5α: Therapeutic Strategy to Inhibit HIV-1 Replication

, 18(17): 2649 - 2654

Jing Zhang, Weiying Ge, Peng Zhan, Erik De Clercq and Xinyong Liu


DOI: 10.2174/092986711795933687




Genetic Bases of Progressive Supranuclear Palsy: The MAPT Tau Disease

, 18(17): 2655 - 2660

Barbara Borroni, Chiara Agosti, Enrico Magnani, Monica Di Luca and Alessandro Padovani


DOI: 10.2174/092986711795933722




Flavonoids as Promising Lead Compounds in Type 2 Diabetes Mellitus: Molecules of Interest and Structure-Activity Relationship

, 18(17): 2661 - 2672

E. Nicolle, F. Souard, P. Faure and A. Boumendjel


DOI: 10.2174/092986711795933777




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