Contents

Current Medicinal Chemistry, Volume 18 - Number 1

Chemical and Pharmacological Chaperones: Application for Recombinant Protein Production and Protein Folding Diseases

, 18(1): 1 - 15

Rahul S. Rajan, Kouhei Tsumoto, Masao Tokunaga, Hiroko Tokunaga, Yoshiko Kita and Tsutomu Arakawa


DOI: 10.2174/092986711793979698




New Therapeutic Approaches Targeted at the Late Stages of the HIV-1 Replication Cycle

, 18(1): 16 - 28

Yan Jiang, Xinyong Liu and Erik De Clercq


DOI: 10.2174/092986711793979751




Functional Roles of Azoles Motif in Anti-HIV Agents

, 18(1): 29 - 46

Peng Zhan, Dongyue Li, Xuwang Chen, Xinyong Liu and Erik De Clercq


DOI: 10.2174/092986711793979733




Progress in the Developement of Positive Allosteric Modulators of the Metabotropic Glutamate Receptor 2

, 18(1): 47 - 68

A. A. Trabanco, J. M. Cid, H. Lavreysen, G. J. Macdonald and G. Tresadern


DOI: 10.2174/092986711793979706




Regulation of Xanthine Oxidase Activity by Substrates at Active Sites via Cooperative Interactions between Catalytic Subunits: Implication to Drug Pharmacokinetics

, 18(1): 69 - 78

L. A. Tai and K. C. Hwang


DOI: 10.2174/092986711793979760




Bioprocess and Bioreactor: Next Generation Technology for Production of Potential Plant-based Antidiabetic and Antioxidant Molecules

, 18(1): 79 - 90

G. Sivakumar, F. Medina-Bolivar, J. O. Lay, M. C. Dolan, J. Condori, S. K. Grubbs, S. M. Wright, M. A. Baque, E. J. Lee and K. Y. Paek


DOI: 10.2174/092986711793979724




Impact of Genetic Variability in Nicotinic Acetylcholine Receptors on Nicotine Addiction and Smoking Cessation Treatment

, 18(1): 91 - 112

P. Russo, A. Cesario, S. Rutella, G. Veronesi, L. Spaggiari, D. Galetta, S. Margaritora, P. Granone and D. S. Greenberg


DOI: 10.2174/092986711793979715




Novel Rational Drug Design Strategies with Potential to Revolutionize Malaria Chemotherapy

, 18(1): 113 - 143

F. W. Muregi, P. G. Kirira and A. Ishih


DOI: 10.2174/092986711793979742




Natural and Synthetic Naphthoquinones Active Against Trypanosoma Cruzi: An Initial Step Towards New Drugs for Chagas Disease

, 18(1): 144 - 161

Cristian O. Salas, Mario Faundez, Antonio Morello, Juan Diego Maya and Ricardo A. Tapia


DOI: 10.2174/092986711793979779




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