Contents

Current Medicinal Chemistry, Volume 11 - Number 5

Preface [Hot Topic: Protein Structure Prediction in Medicinal Chemistry (Guest Editor:Igor F.Tsigelny)]

, 11(5): i

Igor F. Tsigelny


DOI: 10.2174/0929867043455864




SNP Analysis Combined with Protein Structure Prediction Defines Structure- Functional Relationships in Cancer Related Cytochrome P450 Estrogen Metabolism

, 11(5): 525 - 538

Igor F. Tsigelny, Vladimir Kotlovyi and Linda Wasserman


DOI: 10.2174/0929867043455882




Improving the Understanding of Human Genetic Diseases Through Predictions of Protein Structures and Protein-Protein Interaction Sites

, 11(5): 539 - 549

Huan-Xiang Zhou


DOI: 10.2174/0929867043455800




Protein Structure Prediction in Structure Based Drug Design

, 11(5): 551 - 558

Mayuko Takeda-Shitaka, Daisuke Takaya, Chieko Chiba, Hirokazu Tanaka and Hideaki Umeyama


DOI: 10.2174/0929867043455837




Toward Atomic-Scale Understanding of Ligand Recognition in the Muscle Nicotinic Receptor

, 11(5): 559 - 567

Steven M. Sine, Hai-Long Wang and Fan Gao


DOI: 10.2174/0929867043455855




Computational and Experimental Studies on Human Misshapen / NIK- Related Kinase MINK-1

, 11(5): 569 - 582

Kunbin Qu, Yanmei Lu, Nan Lin, Rajinder Singh, Xiang Xu, Donald G. Payan and Dong Xu


DOI: 10.2174/0929867043455873




Using Property Based Sequence Motifs and 3D Modeling to Determine Structure and Functional Regions of Proteins

, 11(5): 583 - 593

Ovidiu Ivanciuc, Numan Oezguen, Venkatarajan S. Mathura, Catherine H. Schein, Yuan Xu and Werner Braun


DOI: 10.2174/0929867043455819




Identification of Functionally Important Residues in Proteins Using Comparative Models

, 11(5): 595 - 605

Shu-wen W. Chen and Jean -Luc Pellequer


DOI: 10.2174/0929867043455891




The Catharanthus Alkaloids:Pharmacognosy and Biotechnology

, 11(5): 607 - 628

Robert van der Heijden, Denise I. Jacobs, Wim Snoeijer, Didier Hallard and Robert Verpoorte


DOI: 10.2174/0929867043455846




Serotonin7 Receptors (5-HT7Rs)and their Ligands

, 11(5): 629 - 661

M. Leopoldo


DOI: 10.2174/0929867043455828




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