Contents

Current Medicinal Chemistry, Volume 10 - Number 20

Preface [Hot Topic: Rational Drug Design and The Discovery of the 1,2,3-Triazolines as a Unique Class of Anticonvulsants and Antiischemic Agents (Guest Editor: Pankaja K. Kadaba)]

, 10(20): ii

Pankaja K. Kadaba


DOI: 10.2174/09298673103020200ii




Ionotropic Glutamate Receptor Biology: Effect on Synaptic Connectivity and Function in Neurological Disease

, 10(20): 2059 - 2072

G. N. Barnes and J. T. Slevin


DOI: 10.2174/0929867033456800




Understanding the Molecular Mechanism of Sigma-1 Receptors: Towards A Hypothesis that Sigma-1 Receptors are Intracellular Amplifiers for Signal Transduction

, 10(20): 2073 - 2080

Tsung-Ping Su and Teruo Hayashi


DOI: 10.2174/0929867033456783




Rational Drug Design and the Discovery of the Δ2-1,2,3-Triazolines, A Unique Class of Anticonvulsant and Antiischemic Agents

, 10(20): 2081 - 2108

Pankaja K. Kadaba


DOI: 10.2174/0929867033456765




Aminoalkylpyridines (AAPs), Triazoline Metabolite Analogues, As Anticonvulsants Highly Effective in the Mes Test

, 10(20): 2109 - 2121

Pankaja K. Kadaba and Trupti Dixit


DOI: 10.2174/0929867033456819




Contribution of Reactive Oxygen Species to Cartilage Degradation in Rheumatic Diseases: Molecular Pathways, Diagnosis and Potential Therapeutic Strategies

, 10(20): 2123 - 2145

J. Schiller, B. Fuchs, J. Arnhold and K. Arnold


DOI: 10.2174/0929867033456828




Brain Nitric Oxide and Its Dual Role in Neurodegeneration / Neuroprotection: Understanding Molecular Mechanisms to Devise Drug Approaches

, 10(20): 2147 - 2174

Antonio Contestabile, Barbara Monti, Andrea Contestabile and Elisabetta Ciani


DOI: 10.2174/0929867033456792




Gene Regulation in Cancer Gene Therapy Strategies

, 10(20): 2175 - 2184

Ian Scanlon, Panos Lehouritis, Ion Niculescu-Duvaz, Richard Marais and Caroline J. Springer


DOI: 10.2174/0929867033456837




Untangling the Functional Potential of PSA-NCAM-Expressing Cells in CNS Development and Brain Repair Strategies

, 10(20): 2185 - 2196

Laurent Nguyen, Jean-Michel Rigo, Brigitte Malgrange, Gustave Moonen and Shibeshih Belachew


DOI: 10.2174/0929867033456774




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