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Current Medicinal Chemistry

Volume 28, 42 Issues, 2021
ISSN: 1875-533X (Online)
ISSN: 0929-8673 (Print)
This journal supports open access

Abstracts Ahead of Print

The Syntheses and Medicinal Attributes of Phenanthrenes as Anticancer Agents: A Quinquennial Update


Sarthak Jhingran, Kritika Laxmikeshav, Sayali Mone, Venkata Rao K and Nagula Shankaraiah*


DOI: 10.2174/0929867328666211018110223
View Abstract




Multicomponent reactions in the synthesis of antiviral compounds


Lorenzo Botta, Silvia Cesarini, Claudio Zippilli, Bruno Mattia Bizzarri, Angelica Fanelli and Raffaele Saladino*


DOI: 10.2174/0929867328666211007121837
View Abstract


Molecular Link between Circadian Rhythmicity and Mood Disorders


Frank Faltraco, Denise Palm, Andrew Coogan, Frederick Simon, Oliver Tucha and Johannes Thome*


DOI: 10.2174/0929867328666211007113725
View Abstract


The Development of Machine Learning Methods in discriminating Secretory Proteins of Malaria Parasite


Ting Liu, Jiamao Chen, Qian Zhang, Kyle Hippe, Cassandra Hunt, Thu Le, Renzhi Cao and Hua Tang*


DOI: 10.2174/0929867328666211005140625
View Abstract


Celecoxib and dimethylcelecoxib block oxidative phosphorylation, epithelial-mesenchymal transition and invasiveness in breast cancer stem cells


Juan Carlos Gallardo-Pérez, Alhelí Adán-Ladrón de Guevara, Marco Antonio García-Amezcua, Diana Xochiquetzal Robledo-Cadena, Silvia Cecilia Pacheco-Velázquez, Javier Alejandro Belmont-Díaz, Jorge Luis Vargas-Navarro, Rafael Moreno-Sánchez and Sara Rodríguez-Enríquez*


DOI: 10.2174/0929867328666211005124015
View Abstract


The Role of Kallikrein 7 in Tumorigenesis


Fengyi Xiang, Yueqing Wang, Chunyu Cao, Qingyun Li, Hao Deng, Jun Zheng, Xiaowen Liu* and Xiao Tan*


DOI: 10.2174/0929867328666210915104537
View Abstract


Potential Role of Adult Hippocampal Neurogenesis in Traumatic Brain Injury


Lucas Alexandre Santos Marzano, Fabyolla Lúcia Macedo de Castro, Caroline Amaral Machado, João Luís Vieira Monteiro de Barros, Thiago Macedo e Cordeiro, Ana Cristina Simões e Silva, Antônio Lúcio Teixeira and Aline Silva de Miranda*


DOI: 10.2174/0929867328666210923143713
View Abstract


Gut Microbiota and Autoimmune Diseases: a Charming Real World Together with Probiotics


Andrea Piccioni, Sara Cicchinelli*, Federico Valletta, Giulio De Luca, Yaroslava Longhitano, Marcello Candelli, Veronica Ojetti, Francesco Sardeo, Simone Navarra, Marcello Covino and Francesco Franceschi


DOI: 10.2174/0929867328666210922161913
View Abstract


Neutrophil/lymphocyte, platelet/lymphocyte and monocyte/lymphocyte ratios in mood disorders


Donatella Marazziti *, Samuele Torrigiani, Manuel G. Carbone, Federico Mucci , Walter Flamini , Tea Ivaldi and Liliana Dell' Osso


DOI: 10.2174/0929867328666210922160116
View Abstract


Different Sides of Depression in the Elderly: An In-depth View on the Role of Aβ Peptides


Giovann Pagni*, Claudia Tagliarini, Manuel Glauco Carbone, Bruno Pietro Imbimbo, Donatella Marazziti and Nunzio Pomara


DOI: 10.2174/0929867328666210921164816
View Abstract


Inflammation, Oxidative Stress, Vascular Aging And Atherosclerotic Ischemic Stroke


Ioannis K. Koutsaliaris, Iraklis C. Moschonas, Louisa M. Pechlivani, Aikaterini N. Tsouka and Alexandros D. Tselepis*


DOI: 10.2174/0929867328666210921161711
View Abstract


Analysis of the molecular mechanisms by flavonoids with potential use for osteoporosis prevention or therapy


Valeria Rodríguez, María Rivoira, Gabriela Picotto, Gabriela Díaz de Barboza, Alejandro Collin and Nori Tolosa de Talamoni*


DOI: 10.2174/0929867328666210921143644
View Abstract


Therapeutic Targets for Phenolic Compounds from Agro-industrial Byproducts against Obesity


María de la Luz Cádiz-Gurrea*, Álvaro Fernández-Ochoa, María del Carmen Villegas-Aguilar, David Arráez-Román and Antonio Segura-Carretero


DOI: 10.2174/0929867328666210920103815
View Abstract






Microbiome in Critical illness: An Unconventional and Unknown Ally


Christian Zanza*, Tatsiana Romenskaya, Duraiyah Thangathurai, Veronica Ojetti, Angela Saviano, Ludovico Abenavoli, Chiara Robba, Gianmaria Cammarota, Francesco Franceschi, Andrea Piccioni and Yaroslava Longhitano


DOI: 10.2174/0929867328666210915115056
View Abstract




Histone Deacetylases and their Inhibitors in Colorectal Cancer Therapy: Current Evidence and Future Considerations


Nikolaos Garmpis*, Christos Damaskos*, Anna Garmpi, Afroditi Nonni, Vasiliki E. Georgakopoulou, Efstathios Antoniou, Dimitrios Schizas, Panagiotis Sarantis, Alexandros Patsouras, Athanasios Syllaios, Christos Vallilas, Evangelos Koustas, Konstantinos Kontzoglou, Nikolaos Trakas and Dimitrios Dimitroulis


DOI: 10.2174/0929867328666210915105929
View Abstract



Virtual Screening and Molecular Docking: Discovering Novel c-KIT Inhibitors


Fernanda Mello Tavares, Angela Cristina Gomes, Edson Mareco Assunção, João Luiz Sobral de Medeiros, Marcus T. Scotti, Luciana Scotti* and Hamilton Mitsugu Ishiki


DOI: 10.2174/0929867328666210915102920
View Abstract




The roles of signaling pathways in cardiac regeneration


Amir Valizadeh, Samira Asghari, Parinaz Mansouri, Forough Alemi, Maryam Majidinia, Ata Mahmoodpoor and Bahman Yousefi*


DOI: 10.2174/0929867328666210914115411
View Abstract


Recent Advances in the Development of Triose Phosphate Isomerase Inhibitors as Antiprotozoal Agents


Lenci K. Vázquez-Jiménez, Antonio Moreno-Herrera, Alfredo Juárez-Saldivar, Alonzo González-González, Eyra Ortiz-Pérez, Alma D. Paz-González, Isidro Palos-Pizarro, Esther Ramírez-Moreno and Gildardo Rivera*


DOI: 10.2174/0929867328666210913090928
View Abstract



Anti-proliferative potential of fluorinated curcumin analogues: experimental and computational analysis and review of the literature


Mahdi Hatamipour, Farzin Hadizadeh, Mahmoud Reza Jaafari, Zahra Khashyarmanesh, Thozhukat Sathyapalan and Amirhossein Sahebkar*


DOI: 10.2174/0929867328666210910141316
View Abstract


A Survey for Predicting ATP Binding Residues of Proteins Using Machine Learning Methods


Yu-He Yang, Jia-Shu Wang, Shi-Shi Yuan, Meng-Lu Liu, Wei Su, Hao Lin* and Zhao-Yue Zhang*


DOI: 10.2174/0929867328666210910125802
View Abstract


The role of celecoxib as a potential inhibitor in the treatment of inflammatory diseases - a review


Josiane Viana Cruz, Joaquín María Campos Rosa*, Njogu Mark Kimani, Silvana Giuliatti and Cleydson Breno Rodrigues dos Santos


DOI: 10.2174/0929867328666210910125229
View Abstract




Recent advances in lung cancer therapy based on nanomaterials: a review


Leila Gholami, Jalil Rouhani Ivari, Niloofar Khandan Nasab, Reza Kazemi Oskuee, Thozhukat Sathyapalan* and Amirhossein Sahebkar*


DOI: 10.2174/0929867328666210810160901
View Abstract


Dual Targeting Strategies On Histone Deacetylase 6 (HDAC6) And Heat Shock Protein 90 (Hsp90)


Davide Bonanni, Andrea Citarella, Davide Moi, Luca Pinzi, Elisa Bergamini and Giulio Rastelli*


DOI: 10.2174/0929867328666210902145102
View Abstract



Prevention and management of type II diabetes chronic complications: the role of polyphenols (Mini-Review)


Arianna Pani, Francesco Baratta, Daniele Pastori, Mattia Coronati, Francesco Scaglione and Maria del Ben*


DOI: 10.2174/0929867328666210902131021
View Abstract


Recent trends on the development of machine learning approaches for the prediction of lysine acetylation sites


Shaherin Basith, Hye Jin Chang, Saraswathy Nithiyanandam, Tae Hwan Shin, Balachandran Manavalan* and Gwang Lee*


DOI: 10.2174/0929867328999210902125308
View Abstract





Molecular Effects of Pteryxin and Scopoletin in the 5xFAD Alzheimer’s Disease Mouse Model


Irem Kiris, Krystyna Skalicka-Wozniak, Merve Karayel Basar, Betul Sahin, Busra Gurel and Ahmet Tarik Baykal*


DOI: 10.2174/0929867328666210827152914
View Abstract


Pulmonary surfactant: a unique biomaterial with life-saving therapeutic applications.


Barbara Pioselli*, Fabrizio Salomone, Giuseppe Mazzola, Davide Amidani, Elisa Sgarbi, Francesco Amadei, Xabi Murgia, Silvia Catinella, Gino Villetti, Daniele De Luca, Virgilio Carnielli and Maurizio Civelli


DOI: 10.2174/0929867328666210825110421
View Abstract



Research Progress on Natural Compounds Exerting an Antidepressant Effect through Anti-inflammatory


Caixia Yuan, Yucen Yao, Tao Liu, Ying Jin*, Chunrong Yang*, Xian Jun Loh and Zibiao Li*


DOI: 10.2174/0929867328666210820115259
View Abstract


Cordycepin as a Promising Inhibitor of SARS-CoV-2 RNA dependent RNA polymerase (RdRp)


Shabana Bibi, Mohammad Mehedi Hasan, Yuan-Bing Wang, Stavros P. Papadakos and Hong Yu*


DOI: 10.2174/0929867328666210820114025
View Abstract



Mucoadhesive Nanosystems for Nose-to-Brain Drug Delivery in the Treatment of Central Nervous System Diseases


Leonardo Delello Di Filippo, Jonatas Duarte, Bruno Fonseca-Santos, Alberto Gomes Tavares Júnior, Victor Araújo, Cesar Augusto Roque Borda, Eduardo Festozo Vicente and Marlus Chorilli*


DOI: 10.2174/0929867328666210813154019
View Abstract


LPS/TLR4 pathways in breast cancer: insights into cell signalling


Rizwana Afroz, E M Tanvir, Mousumi Tania, Junjiang Fu, Mohammad Amjad Kamal and Md. Asaduzzaman Khan*


DOI: 10.2174/0929867328666210811145043
View Abstract


Another look at dietary polyphenols: challenges in cancer prevention and treatment


Roberto Arrigoni, Andrea Ballini*, Luigi Santacroce , Stefania Cantore, Angelo Inchingolo, Francesco Inchingolo , Marina Di Domenico , Lucio Quagliuolo and Mariarosaria Boccellino


DOI: 10.2174/0929867328666210810154732
View Abstract


Structure-based Design of Anti-cancer Vaccines: The Significance of Antigen Presentation to Boost the Immune Response


Alicia Asín, Fayna García-Martín, Jesús Hector Busto, Alberto Avenoza, Jesús Manuel Peregrina* and Francisco Corzana*


DOI: 10.2174/0929867328666210810152917
View Abstract





Metabolomic profiling of exhaled breath condensate and plasma/serum in chronic obstructive pulmonary disease


Salvatore Fuschillo, Debora Paris, Annabella Tramice, Pasquale Ambrosino, Letizia Palomba, Mauro Maniscalco* and Andrea Motta*


DOI: 10.2174/0929867328666210810122350
View Abstract



Flavonoids and PI3K/Akt/mTOR signaling cascade: A potential crosstalk in anticancer treatment


Badar Islam, Mohd Suhail, Mohd Khan, Ajmal Ahmad, Torki Zughaibi, Fohad Husain, Md Tabish Rehman and Shams Tabrez*


DOI: 10.2174/0929867328666210804091548
View Abstract




Recent development of bioinformatics tools for microRNA target prediction


Mst Shamima Khatun, Md Ashad Alam, Watshara Shoombuatong, Md Nurul Haque Mollah, Hiroyuki Kurata* and Md Mehedi Hasan*


DOI: 10.2174/0929867328666210804090224
View Abstract




Natural Products with tandem Anti-inflammatory, Immunomodulatory and Anti-SARS-CoV/2 effects: A Drug Discovery Perspective against SARS-CoV-2


Luana N. O. Leal da Cunha, Tiago Tizziani, Gabriella B. Souza, Monalisa A. Moreira, José S. S. Neto, Carlos V. D. dos Santos, Maryelle G. de Carvalho, Eduardo M. Dalmarco, Leonardo B. Turqueti, Marcus Tullius Scotti, Luciana Scotti, Francisco F. de Assis, Antonio Braga and Louis Pergaud Sandjo*


DOI: 10.2174/0929867328666210726094955
View Abstract


Environmental Factors Modifying HDL Functionality


Constantine E. Kosmas, Andreas Sourlas, Eliscer Guzman and Christina E. Kostara*


DOI: 10.2174/0929867328666210714155422
View Abstract



Epigenetics of Triple-negative breast cancer via natural compounds


Mohammed Kaleem, Maryam Perwaiz, Suza Mohammad Nur, Abdulrasheed O. Abdulrahman, Wasim Ahmad, Fahad A. Al-Abbasi, Vikas Kumar, Mohammad Amjad Kamal and Firoz Anwar*


DOI: 10.2174/0929867328666210707165530
View Abstract



Conformational and Structural characterization of carbohydrates and their interactions studied by NMR


Francisco Javier Cañada*, Ángeles Canales, Pablo Valverde, Beatriz Fernández de Toro, Mónica Martínez-Orts, Paola Oquist Phillips and Amaia Pereda


DOI: 10.2174/0929867328666210705154046
View Abstract


Targeting Chikungunya Virus Entry: alternatives for new inhibitors in drug discovery


Leandro Rocha Silva, Érica Erlanny da Silva Rodrigues, Jamile Taniele-Silva, Letícia Anderson, João Xavier de Araújo-Júnior, Ênio José Bassi and Edeildo F. da Silva-Júnior*


DOI: 10.2174/0929867328666210623165005
View Abstract





Dietary Phytochemicals in Cancer Signalling Pathways: Role of miRNA targeting


Ambreen Shoaib, Mohammad Tabish, Shafat Ali, Azher Arafah, Muneeb U Rehman*, Shadma Wahab, Feras M. Al-Marshadh and Summya Rashid


DOI: 10.2174/0929867328666210420101605
View Abstract


Metal Toxicity and Speciation: A Review


Massimiliano Peana*, Alessio Pelucelli, Serenella Medici, Rosita Cappai, Valeria Marina Nurchi and Maria Antonietta Zoroddu*


DOI: 10.2174/0929867328666210324161205
View Abstract



Editor-in-Chief

Atta-ur-Rahman, FRS
(32052 citations)
Honorary Life Fellow
Kings College
University of Cambridge
Cambridge
(UK)
Biography
View Full Editorial Board

Nobel Laureates on Editorial Board

Prof. John Gurdon
(UK)

Prof. Jean-Marie Lehn
(France)

Prof. Ferid Murad
(USA)

COPE Compliant

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Journal History

Current Medicinal Chemistry was introduced in 1994 with the assistance of Dr. Atta-ur-Rahman, who is the current Editor-in-Chief serving since 1994.

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