Current Medicinal Chemistry
Volume 28, 42 Issues, 2021
ISSN: 1875-533X (Online)
ISSN: 0929-8673 (Print)
This journal supports open access
ISSN: 1875-533X (Online)
ISSN: 0929-8673 (Print)
This journal supports open access
Abstracts Ahead of Print
Translational research of hemoglobin vesicles as a transfusion alternative
Hiromi Sakai*, Naoko Kobayashi, Tomoko Kure and Chie Okuda
DOI: 10.2174/0929867328666210412130035
View Abstract
Recent Insights on Biomedical Applications of Bacterial Cellulose based Composite Hydrogels
Wei Liu, Haishun Du*, Ting Zheng and Chuanling Si*
DOI: 10.2174/0929867328666210412124444
View Abstract
Structure, Function and Modulation of Striatal-enriched Protein Tyrosine Phosphatase (STEP)
Xiao Liang, Xuben Hou* and Hao Fang*
DOI: 10.2174/0929867328666210412123304
View Abstract
A Review on Colorimetric Sensing of Tumor Markers Based on Enzyme-Mimicking Nanomaterials
Hayati Filik*, Asiye Aslıhan Avan and Zehra Füsun Tokatlı
DOI: 10.2174/0929867328666210412122604
View Abstract
Regulatory considerations, challenges and risk-based approach in nanomedicine development
Ildikó Csóka, Ruba Ismail*, Orsolya Jójárt-Laczkovich and Edina Pallagi
DOI: 10.2174/0929867328666210406115529
View Abstract
Insight into the bioactive hydrogels for wound healing and drug delivery systems
Jing Li, Qinhua Chen, Jin Wang, Xiaoyan Pan and Jie Zhang*
DOI: 10.2174/0929867328666210405125348
View Abstract
Factors determining the metal ion binding ability and selectivity of hydroxamate based compounds
Etelka Farkas*, Linda Bíró and Péter Buglyó
DOI: 10.2174/0929867328666210405123952
View Abstract
MiRNAs as Biomarkers in Hypertrophic Cardiomyopathy: Current State of the Art
Andreas Angelopoulos, Evangelos Oikonomou*, Georgia Vogiatzi, Alexios Antonopoulos, Sotirios Tsalamandris, Christos Georgakopoulos, Paraskevi Papanikolaou, George Lazaros, Georgios Charalambous, Gerasimos Siasos, Charalambos Vlachopoulos and Dimitris Tousoulis
DOI: 10.2174/0929867328666210405122703
View Abstract
Recent Advances in the Medicinal Chemistry of Phenothiazines. New Anticancer and Antiprotozoal Agents
Alonzo González-González, Lenci K. Vazquez-Jimenez, Alma D. Paz-González, María Laura Bolognesi and Gildardo Rivera*
DOI: 10.2174/0929867328666210405120330
View Abstract
Recent Applications of Artificial Intelligence in detection of Gastrointestinal, Hepatic and Pancreatic Diseases
Rajnish Kumar*, Farhat Ullah Khan, Anju Sharma, Izzatdin BA Aziz and Nitesh Kumar Poddar
DOI: 10.2174/0929867328666210405114938
View Abstract
The Main Receptors Involved with COVID-19: a Systematic Review and Meta-analysis
Alice Barros Câmara* and Igor Augusto Brandão
DOI: 10.2174/0929867328666210405113253
View Abstract
Natural products targeting cancer stem cells: a revisit
Jiahua Cui*, Jiajun Qian, Larry Ming-Cheung Chow and Jinping Jia
DOI: 10.2174/0929867328666210405111913
View Abstract
Preparation, pharmacokinetic and application of gold nanoclusters (AuNCs) in tumor treatment
Ting Yang, Jun Zhang, Yao Yu* and Taolei Sun*
DOI: 10.2174/0929867328666210331145134
View Abstract
Recent advances of small molecule focal adhesion kinase (FAK) inhibitors as promising anticancer therapeutics
Pengcheng Lv*, Kun Chen* and Hai-Liang Zhu*
DOI: 10.2174/0929867328666210331143827
View Abstract
Nanomedical Applications of Amphiphilic Dendrimeric Micelles
Guillermo Leobardo Rodríguez-Acosta, Carlos Hernández-Montalbán, María Fernanda Sabrina Vega-Razo, Irving Osiel Castillo-Rodríguez and Marcos Martínez-García*
DOI: 10.2174/0929867328666210329125601
View Abstract
Natural Sirtuin Modulators in Drug Discovery: A Review (2010 -2020)
Yuin Chang and Keng Yoon Yeong*
DOI: 10.2174/0929867328666210329124415
View Abstract
Impact of Curcumin on Microsomal Enzyme Activities: Drug Interaction and Chemopreventive Studies
Habibeh Mashayekhi-Sardoo, Adeleh Mashayekhi‐Sardoo, Basil D. Roufogalis, Tannaz Jamialahmadi and Amirhossein Sahebkar*
DOI: 10.2174/0929867328666210329123449
View Abstract
Overview of PCTK3/CDK18: A Cyclin-Dependent Kinase Involved in Specific Functions in Post-Mitotic Cells
Rebeka de Oliveir Pepino, Fernanda Coelho, Tatiane Aparecida Buzanello Janku, Diandra Pinheiro Alencar, Walter Figueira de Azevedo Jr* and Fernanda Canduri*
DOI: 10.2174/0929867328666210329122147
View Abstract
Micro Composite Palmitoylethanolamide/Rutin Reduces Vascular Injury through Modulation of the Nrf2/HO−1 and NF-kB Pathways
Roberta Fusco, Rosalba Siracusa, Enrico Gugliandolo, Alessio Filippo Peritore, Ramona D’Amico, Marika Cordaro, Rosalia Crupi, Daniela Impellizzeri, Chiara Gomiero, Salvatore Cuzzocrea* and Rosanna Di Paola*
DOI: 10.2174/0929867328666210329120213
View Abstract
Overview of natural antiplasmodials from the last decade to inspire medicinal chemistry
Gilles Degotte , Bernard Pirotte, Pierre Francotte and Michel Frédérich*
DOI: 10.2174/0929867328666210329112354
View Abstract
Protein-ligand Docking Simulations with AutoDock4 Focused on the Main Protease of SARS-CoV-2
Walter Filgueira de Azevedo Junior*, Gabriela Bitencourt-Ferreira, Joana Retzke Godoy, Hilda Mayela Aran Adriano, Wallyson André dos Santos Bezerra and Alexandra Martins dos Santos Soares
DOI: 10.2174/0929867328666210329094111
View Abstract
Metal Toxicity and Speciation: A Review
Massimiliano Peana*, Alessio Pelucelli, Serenella Medici, Rosita Cappai, Valeria Marina Nurchi and Maria Antonietta Zoroddu*
DOI: 10.2174/0929867328666210324161205
View Abstract
Algae as a Source of Bioactive Compounds to Prevent the Development of Type 2 Diabetes Mellitus
Jelena B. Popović-Djordjević, Jelena S. Katanić Stanković, Vladimir Mihailović, A.G. Pereira, P. Garcia-Oliveira, M.A. Prieto and J. Simal-Gandara*
DOI: 10.2174/0929867328666210325100654
View Abstract
Phenolic Compounds in Prevention and Treatment of Skin Cancers: a review
Francesca Gado, Maria Digiacomo*, Jasmine Esposito Salsano, Marco Macchia and Clementina Manera
DOI: 10.2174/0929867328666210324160324
View Abstract
Small-molecule Inhibitors of HIV-1 Reverse Transcriptase-Associated Ribonuclease H function: Challenges and Recent Developments.
Valentina Noemi Madia, Antonella Messorea, Alessandro De Leo, Valeria Tudino, Ivano Pindinello, Francesco Saccoliti, Daniela De Vita, Luigi Scipione, Roberta Costi* and Roberto Di Santoa
DOI: 10.2174/0929867328666210322164557
View Abstract
The application of cell-penetrating-peptides in antibacterial agents
Hangfei Chen, Dheerendranath Battalapalli, Mohamed S. Draz, Pengfei Zhang* and Zhi Ruan*
DOI: 10.2174/0929867328666210322162809
View Abstract
Therapeutic potential of natural compounds in lung cancer
Minnatallah Al-Yozbaki, Peter J. Wilkin, Girish Kumar Gupta and Cornelia M. Wilson*
DOI: 10.2174/0929867328666210322103906
View Abstract
Methicillin-resistance Staphylococcus aureus (MRSA) Pyruvate kinase (PK) inhibitors and Their Antimicrobial Activities
Jingjing Jia, Yang Luo, Xue Zhong and Ling He*
DOI: 10.2174/0929867328666210322103340
View Abstract
Recent advances in chalcone-based anticancer heterocycles: A structural and molecular target perspective
Vishal Kumar, Sanjeev Dhawan, Pankaj Sanjay Girase, Paul Awolade, Suraj Raosaheb Shinde, Rajshekhar Karpoormath* and Parvesh Singh*
DOI: 10.2174/0929867328666210322102836
View Abstract
Targeting Never-In-Mitosis-A Related Kinase 5 in Cancer: A Review
Margarite D. Matossian*, Carrow I. Wells, William J. Zuercher, Bridgette M. Collins-Burow, David H. Drewry* and Matthew E. Burow*
DOI: 10.2174/0929867328666210322101749
View Abstract
The Emerging Landscapes to Drug Delivery Systems for the Treatment of Pancreatic Cancer
Agnes Magri*, Franciele Garcia Baveloni, Bruna Almeida Furquim de Camargo and Marlus Chorilli*
DOI: 10.2174/0929867328666210319144347
View Abstract
Study the role of Probiotics and Prebiotics in osteolastogenesis and immune relevance
Datong Li, Yuan Liu, Xiaobin Yang and Lingbo Kong*
DOI: 10.2174/0929867328666210316115126
View Abstract
Inhibiting the “Undruggable” RAS/Farnesyltransferase (FTase) Cancer Target by Manumycin-related Natural Products
Leandro Rocha Silva and Edeildo Ferreira da Silva-Júnior *
DOI: 10.2174/0929867328666210315123848
View Abstract
The use of L-glucose in cancer diagnosis: Results from In Vitro and In Vivo Studies
Ioanna A. Anastasiou*, Ioanna Eleftheriadou, Anastasios Tentolouris, Iordanis Mourouzis, Constantinos Pantos and Nikolaos Tentolouris*
DOI: 10.2174/0929867328666210311112240
View Abstract
Bladder Cancer: Update on Risk Factors, Molecular and Ultrastructural Patterns
Liudmila M. Mikhaleva*, Valentina V. Pechnikova, Akhmed M. Pshikhachev, Konstantin A. Rogov, Magomed A. Gusniev, Olga I. Patsap, Olesya A. Vasyukova, Emma P. Akopyan, Ozal Beylerli, Siva G. Somasundaram, Cecil E. Kirkland and Gjumrakch Aliev*
DOI: 10.2174/0929867328666210309111731
View Abstract
The Effect of Natural Soluble Polysaccharides On the Type 2 Diabetes through Modulating Gut Microbiota:A review
Lina Yang*, Li Li, Xinghui Wu, Wenqi Cai, Qian Lin, Danshi Zhu and He Liu*
DOI: 10.2174/0929867328666210309110352
View Abstract
Natural sourced inhibitors of EGFR, PDGFR, FGFR and VEGFR-mediated signaling pathways as potential anticancer agents
Sisir Nandi*, Rishita Dey, Asmita Samadder, Aaruni Saxena and Anil Kumar Saxena*
DOI: 10.2174/0929867328666210303101345
View Abstract
Astrocytes and Inflammasome: A Possible Crosstalk in Neurological Diseases
Fahimeh Nourbakhsh, Morgayn I. Read, George E. Barreto and Amirhossein Sahebkar*
DOI: 10.2174/0929867328666210301105422
View Abstract
Engineered polymer nanoplatforms for targeted tumor cells and controlled release cargos to enhance cancer treatment
Zhenjie Wang, Longguang Tang, Qingchun Mu, Siyao Che*, Yongbing Sun*, Lei Bai, Yan Luo, Yeguo Yang, Meng Yu and Zhiqiang Yu*
DOI: 10.2174/0929867328666210226143148
View Abstract
Latest advances in hydrogel-based drug delivery systems for optimization of metabolic syndrome treatment
Diego Arauna, Sekar Vijayakumar and Esteban Durán-Lara*
DOI: 10.2174/0929867328666210223141555
View Abstract
ICP-MS-based approach to determine nanoparticle recovery after hollow fiber flow field flow fractionation
Fabian L. Kriegel, Benjamin C. Krause, Yves U. Hachenberger*, Rafael Fister, Philipp Reichardt, Jutta Tentschert, Ajay-Vikram Singh*, Harald Jungnickel, Peter Laux and Andreas Luch
DOI: 10.2174/0929867328666210222094913
View Abstract
Lipid-Lowering Therapies for Atherosclerosis: Statins, Fibrates, Ezetimibe and PCSK9 monoclonal antibodies
Adel Hajj Ali, Nour Younis, Rola Abdallah, Farah Shaer, Ali Dakroub, Mohammed Ayoub, Rabah Iratni, Hadi Mohamad Yassine, Kazem Zibara, Alexander Orekhov, Ahmed Fawzy El-Yazbi and Ali Eid *
DOI: 10.2174/0929867328666210222092628
View Abstract
The link between bacterial inflammagens, leaky gut syndrome and colorectal cancer
Greta M de Waal*, Willem JS de Villiers and Etheresia Pretorius*
DOI: 10.2174/0929867328666210219142737
View Abstract
Advances of Inorganic Materials in the Detection and Therapeutic Uses Against Coronaviruses
Sathish Veerasamy*, Manivannan Chandrakumar, Malathi Balasubramaniyan, Ramesh Kumar Arumugam and Thanasekaran Pounraj*
DOI: 10.2174/0929867328666210219142208
View Abstract
Current Trends in the Therapeutic Strategies for Diabetes Management
Ponnurengam Malliappan Siva Kumar, V. Prabhawathi, Ali Zarrabi, Sohail Akthar and Pranav Kumar Prabhakar*
DOI: 10.2174/0929867328666210218183914
View Abstract
Recent Multi-Target Approaches on the Development of Anti-Alzheimer`s Agents Integrating Metal Chelation Activity
Sílvia Chaves, Katalin Várnagy and M. Amélia Santos*
DOI: 10.2174/0929867328666210218183032
View Abstract
Transcriptional control of the oxidative stress response and implications of using plant derived molecules for therapeutic interventions in cancer
Asim Rizvi, Mohd. Farhan, Faisal Nabi, Rizwan Hasan Khan, Mohd. Adil and Aamir Ahmad*
DOI: 10.2174/0929867328666210218110550
View Abstract
Antimicrobial activity of 5-membered nitroheteroaromatic compounds beyond nitrofurans and nitroimidazoles: recent progress
Stanislav Kalinin, Tatiana Vedekhina, Polina Paramonova and Mikhail Krasavin*
DOI: 10.2174/0929867328666210216114838
View Abstract
Nuclear long non-coding RNAs as epigenetic regulators in cancer
Hiroaki Tachiwana and Noriko Saitoh*
DOI: 10.2174/0929867328666210215114506
View Abstract
Trefoil Factor Family (TFF) Peptides and their Different Roles in the Mucosal Innate Immune Defense and More: An Update
Werner Hoffmann*
DOI: 10.2174/0929867328666210215114140
View Abstract
Design and Synthesis of Novel Aminoalkanamides Targeting Neurodegeneration and Symptoms of Alzheimer’s Disease
Agnieszka Jankowska, Grzegorz Satała, Gniewomir Latacz, Anna Partyka, Annamaria Lubelska, Krzysztof Pociecha, Artur Świerczek, Natalia Wilczyńska, Barbara Mordyl, Andrzej J. Bojarski, Elżbieta Wyska and Grażyna Chłoń-Rzepa*
DOI: 10.2174/0929867328666210215113346
View Abstract
Renin Angiotensin System in Central Nervous System diseases and its interaction with COVID-19
Katharina Lanza, Raphael Dias, Rafaela dos Santos Oliveira, Luís Belotto, Aline Silva Miranda and Ana Cristina Simões e Silva*
DOI: 10.2174/0929867328666210212101854
View Abstract
Chemistry and Anticancer Activity of Hybrid Molecules and Derivatives Based on 5-Fluorouracil
Wilson Cardona-G*, Angie Herrera-R, Wilson Castrillón-L and Howard Ramírez-Malule
DOI: 10.2174/0929867328666210211164314
View Abstract
Novel nitrogen containing steroid derivatives for prostate cancer treatment
Alexandra S. Latysheva, Vladimir A. Zolottsev, Vadim S. Pokrovsky*, Irina I. Khan and Alexander Yu. Misharin
DOI: 10.2174/0929867328666210208113919
View Abstract
A Review of Water-Resistant Cellulose-Based Materials in Pharmaceutical and Biomedical Application
Bei He, Xinxin Liu*, Shi Qi, Run Zheng, Minmin Chang, Qixuan Lin and Junli Ren*
DOI: 10.2174/0929867328666210208113354
View Abstract
Advancements within modern machine learning methodology: Impacts and prospects for biomarker discovery
Dakila Ledesma*, Steven Symes and Sean Richards
DOI: 10.2174/0929867328666210208111821
View Abstract
Current phthalocyanines delivery systems in photodynamic therapy: an updated review
Mariana Miretti*, Cesar German Prucca, Tomas Cristian Tempesti and Maria Teresa Baumgartner*
DOI: 10.2174/0929867328666210208111234
View Abstract
Targeting Viral RNA-Dependent RNA Polymerases as an Antiviral Therapy
Daniel Miranda and David Jesse Sanchez*
DOI: 10.2174/0929867328666210204205726
View Abstract
Artificial Intelligence: the “Trait D’Union” in Different Analysis Approaches of Autism Spectrum Disorder Studies
Francesca Marciano*, Giorgia Venutolo, Carminia Marina Ingenito, Antonella Verbeni, Concetta Terracciano, Elizabeth Plunk, Francesco Garaci, Armando Cavallo and Alessio Fasano
DOI: 10.2174/0929867328666210203205221
View Abstract
Development of Novel Rhodacyanine-Based Heat Shock Protein 70 Inhibitors
Chih-Shiang Chang, Vathan Kumar, Der-Yen Lee, Yeh Chen, Yu-Chieh Wu, Jing-Yan Gao and Po-Chen Chu*
DOI: 10.2174/0929867328666210203204254
View Abstract
Dynamics of Toll-like receptors signaling in skeletal muscle atrophy
Aarti Yadav, Anil Dahuja and Rajesh Dabur*
DOI: 10.2174/0929867328666210202113734
View Abstract
Recent Progress in Small Molecular Inhibitors of DNA Gyrase
Ruo-Jun Man, Xu-Ping Zhang, Yu-Shun Yang*, Ai-Qin Jiang* and Hai-Liang Zhu*
DOI: 10.2174/1871529X21666210202113128
View Abstract
The Role of Sialylation in Respiratory Viral Infection and Treatment
Harrison Steele, Andrew J. Tague and Danielle Skropeta*
DOI: 10.2174/0929867328666210201153901
View Abstract
Evidence of protein binding by a nucleopeptide based on a thymine-decorated L-diaminopropanoic acid through CD and in silico studies
Valentina Roviello, Domenica Musumeci, Andriy Mokhir and Giovanni N. Roviello*
DOI: 10.2174/0929867328666210201152326
View Abstract
Natural Products as Potential Agents Against SARS-CoV and SARS-CoV-2
Joanda Paolla Raimundo e Silva, Chonny Alexander Herrera Acevedo, Thalisson Amorim de Souza, Renata Priscila Barros de Menezes, Zoe L. Sessions, Lucas Silva Abreu, Samuel Paulo Cibulski, Luciana Scotti, Marcelo Sobral da Silva, Eugene N. Muratov, Marcus Tullius Scotti and Josean Fechine Tavares*
DOI: 10.2174/0929867328666210125113938
View Abstract
A Review of Light Sources and Enhanced Targeting for Photodynamic Therapy.
Menghua Xiang, Quanming Zhou, Zihan Shi, Xuan Wang, Mengchu Li, Yan Jia, Shaoyun Li, Fen Yang, Wei Wang, Bigyan Sharma, Yichu Nie, Qicai Xiao*, Liqian Gao*, Tongkai Chen and Xiaojun Xu
DOI: 10.2174/0929867328666210121122106
View Abstract
Preparation and formulation optimization of methotrexate-loaded human serum albumin nanoparticles modified by mannose
Zhenyu Chen, Zhongling Luo, Jiayao Lyu, Jianxin Wang, Zhongbing Liu, Jun Wei, Yan Lin* and Zhirong Zhong*
DOI: 10.2174/0929867328666210118112640
View Abstract
A Novel Dicationic Boron Dipyrromethene-based Photosensitizer for Antimicrobial Photodynamic Therapy against Methicillin-Resistant Staphylococcus aureus
Priyanga Dharmaratne, Ligang Yu, Roy Chi-Hang Wong, Ben Chun-Lap Chan, Kit-Man Lau, Baiyan Wang, Clara Bik-San Lau, Kwok-Pui Fung, Dennis Kee-Pui Ng and Margaret Ip*
DOI: 10.2174/0929867328666201208095105
View Abstract
Editor-in-Chief
Atta-ur-Rahman, FRS
(32052 citations)
Honorary Life Fellow
Kings College
University of Cambridge
Cambridge
(UK)
Biography
(32052 citations)
Honorary Life Fellow
Kings College
University of Cambridge
Cambridge
Biography
Biography of Atta-ur-Rahman
Prof. Atta-ur-Rahman, Ph.D. in organic chemistry from Kings College, University of Cambridge (1968), has 1235 international publications in several fields of organic chemistry including, 349 books published largely by major U.S. and European presses. He was elected as Fellow of Royal Society (London) (2006) and won the prestigious UNESCO Science Prize (1999).
Prof. Atta-ur-Rahman was conferred honorary D.Sc. degrees by many leading world universities including the University of Cambridge and appointed an Honorary Life Fellow of Kings College, University of Cambridge. The Austrian government honoured him with its high civil award (“Grosse Goldene Ehrenzeischen am Bande") (2007). He is Professor Emeritus at the University of Karachi, Pakistan. Prof. Atta-ur-Rahman was appointed Academician (Foreign Member) of the Chinese Academy of Sciences (2015). He won the “Friendship Award of China” (2014) and was conferred the highest scientific award of China, the International Science & Technology Cooperation Award, by President Xi Jinping (2020). He was bestowed with the International Scientific Corporation Award (2014) and the “Einstein Professorship” by the Chinese Academy of Sciences (CAS) (2013). He was also elected as Foreign Member of the Korean Academy of Science and Technology. Research Institutes have been established in his name in China, Malaysia and Pakistan.
Nobel Laureates on Editorial Board
Prof. John Gurdon
(UK)
Prof. Jean-Marie Lehn
(France)
Prof. Ferid Murad
(USA)
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Journal History
Current Medicinal Chemistry was introduced in 1994 with the assistance of Dr. Atta-ur-Rahman, who is the current Editor-in-Chief serving since 1994.
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