Open Access Articles

Vitamin D Receptor: A Novel Therapeutic Target for Kidney Diseases

, 2018; 25(27): 3256 - 3271

Shikun Yang, Aimei Li, JianWen Wang, Jun Liu, Yachun Han, Wei Zhang, Yan Chun Li and Hao Zhang*




Serotonin Receptor Binding Characteristics of Geissoschizine Methyl Ether, an Indole Alkaloid in Uncaria Hook

, 2018; 25(9): 1036 - 1045

Yasushi Ikarashi, Kyoji Sekiguchi and Kazushige Mizoguchi*





The Interplay between G-quadruplex and Transcription

, 2018; 25: 1 - 19 (E-Pub Ahead of Print)

Nayun Kim*




Common Aspects Influencing the Translocation of SERS to Biomedicine

, 2018; 25: 1 - 15 (E-Pub Ahead of Print)

Dionysia Tsoutsi, Marcos Sanles-Sobrido, Andreu Cabo and Pilar Rivera Gil*




Immunocontraception: Filamentous Bacteriophage as a Platform for Vaccine Development

, 2017; 24(35): 3907 - 3920

Tatiana I. Samoylova*, Timothy D. Braden, Jennifer A. Spencer and Frank F. Bartol





A Systematic Analysis of Physicochemical and ADME Properties of All Small Molecule Kinase Inhibitors Approved by US FDA from January 2001 to October 2015

, 2017; 24(29): 3159 - 3184

Zhihong O`Brien and Mehran F. Moghaddam*





Therapeutic Strategies of Plant-derived Compounds for Diabetes Via Regulation of Monocyte Chemoattractant Protein-1

, 2017; 24(14): 1453 - 1468

Magdalena Czemplik*, Anna Kulma, Yu Fu Wang and Jan Szopa





Mycosporine-Like Amino Acids for Skin Photoprotection

, 2017; 24: 1 - 16 (E-Pub Ahead of Print)

Karl P Lawrence, Paul F Long and Antony R Young*




Fighting Type-2 Diabetes: Present and Future Perspectives

, 2017; 24: 1 - 17 (E-Pub Ahead of Print)

Cai-Guo Yu , Ying Fu, Yuan Fang , Ning Zhang, Rong-Xin Sun , Dong Zhao, Ying-Mei Feng and Bao-Yu Zhang*




Untargeted Metabolomics Provides Insight into the Mechanisms Underlying Resistant Hypertension

, 2017; 24: 1 - 12 (E-Pub Ahead of Print)

Renata Bujak, Arlette Yumba-Mpanga, Wiktoria Struck-Lewicka, Marta Kordalewska, Katarzyna Polonis, Małgorzata Patejko, Monika Mironiuk, Anna Szyndle, Marzena Chrostowska, Michał Hoffmann, Ryszard T. Smoleński, Roman Kaliszan, Krzysztof Narkiewicz and Michał J. Markuszewski*





Osteoimmunology and Beyond

, 2016; 23(33): 3754 - 3774

Lia Ginaldi and Massimo De Martinis





Why Antidiabetic Vanadium Complexes are Not in the Pipeline of “Big Pharma” Drug Research? A Critical Review

, 2016; 23(25): 2874 - 2891

Thomas Scior, Jose Antonio Guevara-Garcia, Quoc-Tuan Do, Philippe Bernard and Stefan Laufer




A Compendium of Volatile Organic Compounds (VOCs) Released By Human Cell Lines

, 2016; 23(20): 2112 - 2131

Wojciech Filipiak, Pawel Mochalski, Anna Filipiak, Clemens Ager, Raquel Cumeras, Cristina E. Davis, Agapios Agapiou, Karl Unterkofler and Jakob Troppmair




Structure and Expression of Different Serum Amyloid A (SAA) Variants and their Concentration-Dependent Functions During Host Insults

, 2016; 23(17): 1725 - 1755

Mieke De Buck, Mieke Gouwy, Ji Ming Wang, Jacques Van Snick, Ghislain Opdenakker, Sofie Struyf and Jo Van Damme





Food Proteins as Source of Opioid Peptides-A Review

, 2016; 23(9): 893 - 910

Swati Garg, Kulmira Nurgali and Vijay Kumar Mishra





Serotonin 1A Receptors on Astrocytes as a Potential Target for the Treatment of Parkinson’s Disease

, 2016; 23(7): 686 - 700

Ikuko Miyazaki and Masato Asanuma




Role of Tyrosine Isomers in Acute and Chronic Diseases Leading to Oxidative Stress - A Review

, 2016; 23(7): 667 - 685

Gergő A. Molnár, Szilárd Kun, Eszter Sélley, Melinda Kertész, Lívia Szélig, Csaba Csontos, Katalin Böddi, Lajos Bogár, Attila Miseta and István Wittmann




Eosinophils in Cancer: Favourable or Unfavourable?

, 2016; 23(7): 650 - 666

Samy Sakkal, Sarah Miller, Vasso Apostolopoulos and Kulmira Nurgali





Action of Nanoparticles on Platelet Activation and Plasmatic Coagulation

, 2016; 23(5): 408 - 430

Eleonore Fröhlich





Non-Traditional Systemic Treatments for Diabetic Retinopathy: An Evidence-Based Review

, 2015; 22(21): 2580 - 2589

Rafael Simo, Stefania Ballarini, Jose Cunha-Vaz, Linong Ji, Hermann Haller, Paul Zimmet and Tien Y Wong





Key Sites for P2X Receptor Function and Multimerization: Overview of Mutagenesis Studies on a Structural Basis

, 2015; 22(7): 799 - 818

Ralf Hausmann, Achim Kless and Gunther Schmalzing





Novel Strategies for Preventing Diabetes and Obesity Complications with Natural Polyphenols

, 2015; 22(1): 150 - 164

C. Carpene, S. Gomez-Zorita, S. Deleruyelle and M.A. Carpene





A Common Molecular Motif Characterizes Extracellular Allosteric Enhancers of GPCR Aminergic Receptors and Suggests Enhancer Mechanism of Action

, 2014; 21(32): 3673 - 3686

Robert Root-Bernstein and Patrick F. Dillon





In Vitro and In Vivo Models for Analysis of Resistance to Anticancer Molecular Therapies

, 2014; 21(14): 1595 - 1606

Roberta Rosa, Francesca Monteleone, Nicola Zambrano and Roberto Bianco





Exogenous Hormonal Regulation in Breast Cancer Cells by Phytoestrogens and Endocrine Disruptors

, 2014; 21(9): 1129 - 1145

A. Albini, C. Rosano, G. Angelini, A. Amaro, A.I. Esposito, S. Maramotti, D.M. Noonan and U. Pfeffer





Phytoestrogens in Postmenopause: The State of the Art from a Chemical, Pharmacological and Regulatory Perspective

, 2014; 21(4): 417 - 436

Elisabetta Poluzzi, Carlo Piccinni, Emanuel Raschi, Angela Rampa, Maurizio Recanatini and Fabrizio De Ponti





An Up-date of Olive Oil Phenols in Inflammation and Cancer: Molecular Mechanisms and Clinical Implications

, 2013; 20(37): 4758 - 4776

A. Cárdeno, M. Sánchez-Hidalgo and C. Alarcón-de-la-Lastra




Reduction of Breast Cancer Relapses with Perioperative Non-Steroidal Anti-Inflammatory Drugs: New Findings and a Review

, 2013; 20(33): 4163 - 4176

Michael Retsky, Romano Demicheli, William J.M. Hrushesky, Patrice Forget, Marc De Kock, Isaac Gukas, Rick A Rogers, Michael Baum, Vikas Sukhatme and Jayant S. Vaidya




Medicinal Chemistry of the Epigenetic Diet and Caloric Restriction

, 2013; 20(32): 4050 - 4059

S. L. Martin, T. M. Hardy and T. O. Tollefsbol





Free Fatty Acids-Sensing G Protein-Coupled Receptors in Drug Targeting and Therapeutics

, 2013; 20(31): 3855 - 3871

Tomo Yonezawa, Riho Kurata, Kaori Yoshida, Masanori A. Murayama, Xiaofeng Cui and Akihiko Hasegawa





A Novel Promising Therapeutic Option Against Hepatitis C Virus: An Oral Nucleotide NS5B Polymerase Inhibitor Sofosbuvir

, 2013; 20(30): 3733 - 3742

I. Gentile, F. Borgia, A. R. Buonomo, G. Castaldo and G. Borgia





MicroRNAs and Cancer Therapy – From Bystanders to Major Players

, 2013; 20(29): 3561 - 3573

Cornelia Braicu, George A. Calin and Ioana Berindan-Neagoe





Mitochondria Damage in the Pathogenesis of Diabetic Retinopathy and in the Metabolic Memory Associated with its Continued Progression

, 2013; 20(26): 3226 - 3233

Renu A. Kowluru




Calpains: Potential Targets for Alternative Chemotherapeutic Intervention Against Human Pathogenic Trypanosomatids

, 2013; 20(25): 3174 - 3185

M. H. Branquinha, F. A. Marinho, L. S. Sangenito, S. S.C. Oliveira, K. C. Goncalves, V. Ennes-Vidal, C. M. d’Avila-Levy and A. L.S. Santos




Aspartic Peptidases of Human Pathogenic Trypanosomatids: Perspectives and Trends for Chemotherapy

, 2013; 20(25): 3116 - 3133

L. O. Santos, A. S. Garcia-Gomes, M. Catanho, C. L. Sodre, A. L.S. Santos, M. H. Branquinha and C. M. d’Avila-Levy





Synthetic and Natural Protease Inhibitors Provide Insights into Parasite Development, Virulence and Pathogenesis

, 2013; 20(25): 3078 - 3102

A. A. Rascon and J. H. McKerrow





An Overview on Natural Polysaccharides with Antioxidant Properties

, 2013; 20(23): 2899 - 2913

H. Wang, Y. M. Liu, Z. M. Qi, S. Y. Wang, S. X. Liu, X. Li, H. J. Wang and X. C. Xia





Trypanosomatidae Diseases: From the Current Therapy to the Efficacious Role of Trypanothione Reductase in Drug Discovery

, 2013; 20(21): 2673 - 2696

L.S.C. Bernardes, C.L. Zani and I. Carvalho




Flavonoids in Atherosclerosis: An Overview of Their Mechanisms of Action

, 2013; 20(21): 2641 - 2660

G. Siasos, D. Tousoulis, V. Tsigkou, E. Kokkou, E. Oikonomou, M. Vavuranakis, E.K. Basdra, A.G. Papavassiliou and C. Stefanadis




Bioavailability of Quercetin: Problems and Promises

, 2013; 20(20): 2572 - 2582

X. Cai, Z. Fang, J. Dou, A. Yu and G. Zhai





Piroxicam-β-Cyclodextrin: A GI Safer Piroxicam

, 2013; 20(19): 2415 - 2437

C. Scarpignato




Insulin Secretion and Interleukin-1β Dependent Mechanisms in Human Diabetes Remission After Metabolic Surgery

, 2013; 20(18): 2374 - 2388

Chih-Yen Chen, Wei-Jei Lee, A. Asakawa, N. Fujitsuka, Keong Chong, Shu-Chun Chen, Shou-Dong Lee and A. Inui




1,2,4-Oxadiazoles Identified by Virtual Screening and their Non-Covalent Inhibition of the Human 20S Proteasome

, 2013; 20(18): 2351 - 2362

X. Maréchal, E. Genin, L. Qin, O. Sperandio, M. Montes, N. Basse, N. Richy, M.A. Miteva, M. Reboud-Ravaux, J. Vidal and B.O. Villoutreix




Luminescent Silica Nanoparticles for Cancer Diagnosis

, 2013; 20(17): 2195 - 2211

W. Arap, R. Pasqualini, M. Montalti, L. Petrizza, L. Prodi, E. Rampazzo, N. Zaccheroni and S. Marchio




Computational Peptidology: A New and Promising Approach to Therapeutic Peptide Design

, 2013; 20(15): 1985 - 1996

P. Zhou, C. Wang, Y. Ren, C. Yang and F. Tian




Targeting the Akt Kinase to Modulate Survival, Invasiveness and Drug Resistance of Cancer Cells

, 2013; 20(15): 1923 - 1945

Giuliana Cassinelli, Valentina Zuco, Laura Gatti, Cinzia Lanzi, Nadia Zaffaroni, Diego Colombo and Paola Perego




Histone Deacetylase Inhibitors: An Attractive Strategy for Cancer Therapy

, 2013; 20(14): 1858 - 1886

Jiyang Li, Guangqiang Li and Wenqing Xu





Multi-Target Compounds Acting in the Central Nervous System Designed From Natural Products

, 2013; 20(13): 1673 - 1685

X. Chen and M. Decker





The Economics of Polypharmacology: Fixed Dose Combinations and Drug Cocktails

, 2013; 20(13): 1635 - 1638

A. I. Wertheimer





Long-Acting Beta-Agonists and their Association with Inhaled Corticosteroids in COPD

, 2013; 20(12): 1477 - 1495

L. Fuso, N. Mores, S. Valente, M. Malerba and P. Montuschi





Serenoa Repens, Lycopene and Selenium: A Triple Therapeutic Approach to Manage Benign Prostatic Hyperplasia

, 2013; 20(10): 1306 - 1312

L. Minutoli, A. Bitto, F. Squadrito, H. Marini, N. Irrera, G. Morgia, A. Passantino and D. Altavilla




Ion Channels as Drug Targets in Central Nervous System Disorders

, 2013; 20(10): 1241 - 1285

A. M. Waszkielewicz, A. Gunia, N. Szkaradek, K. Sloczynska, S. Krupinska and H. Marona




Plant Metabolomics: From Holistic Data to Relevant Biomarkers

, 2013; 20(8): 1056 - 1090

Jean-Luc Wolfender, Serge Rudaz, Young Hae Choi and Hye Kyong Kim





Antimicrobial Plant Metabolites: Structural Diversity and Mechanism of Action

, 2013; 20(7): 932 - 952

N.S. Radulovic, P.D. Blagojevic, Z.Z. Stojanovic-Radic and N.M. Stojanovic




The Pentacyclic Triterpenoids in Herbal Medicines and Their Pharmacological Activities in Diabetes and Diabetic Complications

, 2013; 20(7): 908 - 931

A. Alqahtani, K. Hamid, A. Kam, K.H. Wong, Z. Abdelhak, V. Razmovski-Naumovski, K. Chan, K.M. Li, P.W. Groundwater and G.Q. Li




Survey of Recent Literature Related to the Biologically Active 4(3H)-Quinazolinones Containing Fused Heterocycles

, 2013; 20(6): 794 - 814

Martine Demeunynck and Isabelle Baussanne





Honey as a Source of Dietary Antioxidants: Structures, Bioavailability and Evidence of Protective Effects Against Human Chronic Diseases

, 2013; 20(5): 621 - 638

Josè M. Alvarez-Suarez, Francesca Giampieri and Maurizio Battino





The Current Status of Sweat Testing For Drugs of Abuse: A Review

, 2013; 20(4): 545 - 561

N. De Giovanni and N. Fucci





Do Subjects at Clinical High Risk for Psychosis Differ from those with a Genetic High Risk? - A Systematic Review of Structural and Functional Brain Abnormalities

, 2013; 20(3): 467 - 481

R. Smieskova, J. Marmy, A. Schmidt, K. Bendfeldt, A. Riecher-Rossler, M. Walter, U. E. Lang and S. Borgwardt





Transcranial Brain Stimulation in Schizophrenia: Targeting Cortical Excitability, Connectivity and Plasticity

, 2013; 20(3): 405 - 413

A. Hasan, P. Falkai and T. Wobrock





Serotonin Receptors of Type 6 (5-HT6): From Neuroscience to Clinical Pharmacology

, 2013; 20(3): 371 - 377

Donatella Marazziti, Stefano Baroni, Franco Borsini, Michela Picchetti, Elena Vatteroni, Valentina Falaschi and Mario Catena-Dell’Osso





Histone Methyltransferase Inhibitors: Novel Epigenetic Agents for Cancer Treatment

, 2013; 20(2): 167 - 185

C. Zagni, U. Chiacchio and A. Rescifina





Recent Lipase-Catalyzed Hydrolytic Approaches to Pharmacologically Important β-and λ-Amino Acids

, 2012; 19(36): 6178 - 6187

E. Forro and F. Fulop





Stem Cells, Self-Renewal and Cancer of the Gastric Epithelium

, 2012; 19(35): 5975 - 5983

Werner Hoffmann





Polarization of Calcium Signaling and Fluid Secretion in Salivary Gland Cells

, 2012; 19(34): 5774 - 5781

I. S. Ambudkar





Contribution of Oxidative Metabolism to Cocaine-Induced Liver and Kidney Damage

, 2012; 19(33): 5601 - 5606

M.J. Valente, F. Carvalho, M.d.L. Bastos, P.G. de Pinho and M. Carvalho





Protective Role of Adiponectin in Cardiovascular Disease

, 2012; 19(32): 5459 - 5466

R. Shibata, T. Murohara and N. Ouchi





Immunoliposomes

, 2012; 19(31): 5239 - 5277

E. Paszko and M.O. Senge





Fragment Based Drug Design: From Experimental to Computational Approaches

, 2012; 19(30): 5128 - 5147

A. Kumar, A. Voet and K.Y.J. Zhang





Fluorescent Dendrimers As Sensors for Biologically Important Metal Cations

, 2012; 19(29): 4976 - 4983

I. Grabchev, D. Staneva and R. Betcheva





Recent Advances in Receptor-Targeted Fluorescent Probes for In Vivo Cancer Imaging

, 2012; 19(28): 4742 - 4758

M. Bai and D. J. Bornhop





Review Metabolomics: A New Approach to Drug Delivery in Perinatology

, 2012; 19(27): 4654 - 4661

L. Atzori, J. L. Griffin, A. Noto and V. Fanos





Biology and Clinical Management of Myeloproliferative Neoplasms and Development of the JAK Inhibitor Ruxolitinib

, 2012; 19(26): 4399 - 4413

J. Mascarenhas, T. I. Mughal and S. Verstovsek




Insights into Targeting Colon Cancer Cell Fate at the Level of Proteoglycans / Glycosaminoglycans

, 2012; 19(25): 4247 - 4258

D. Nikitovic, G. Chatzinikolaou, J. Tsiaoussis, A. Tsatsakis, N. K. Karamanos and G. N. Tzanakakis




The Synergistic Effects of DNA-Targeted Chemotherapeutics and Histone Deacetylase Inhibitors As Therapeutic Strategies for Cancer Treatment

, 2012; 19(25): 4218 - 4238

M. Stiborova, T. Eckschlager, J. Poljakova, J. Hrabeta, V. Adam, R. Kizek and E. Frei





Chromogranin-A: A Multifaceted Cardiovascular Role in Health and Disease

, 2012; 19(24): 4042 - 4050

T. Angelone, R. Mazza and M. C. Cerra




Glutathione-Related Factors and Oxidative Stress in Autism, A Review

, 2012; 19(23): 4000 - 4005

A. Ghanizadeh, S. Akhondzadeh, M. Hormozi, A. Makarem, M. Abotorabi-Zarchi and A. Firoozabadi




Role of PARP Inhibitors in Cancer Biology and Therapy

, 2012; 19(23): 3907 - 3921

D. Davar, J. H. Beumer, L. Hamieh and H. Tawbi





Homeostasis and the Importance for a Balance Between AKT/mTOR Activity and Intracellular Signaling

, 2012; 19(22): 3748 - 3762

D. A. Altomare and A. R. Khaled





Survivin as a Prognostic/Predictive Marker and Molecular Target in Cancer Therapy

, 2012; 19(22): 3679 - 3688

F. Rodel, T. Sprenger, B. Kaina, T. Liersch, C. Rodel, S. Fulda and S. Hehlgans





Recent Progress in the Development of Agonists and Antagonists for Melatonin Receptors

, 2012; 19(21): 3532 - 3549

D. P. Zlotos





Radiolabelled Agents for PET Imaging of Tumor Hypoxia

, 2012; 19(20): 3282 - 3289

H. Kurihara, N. Honda, Y. Kono and Y. Arai





Drug-Loaded Nanocarriers: Passive Targeting and Crossing of Biological Barriers

, 2012; 19(19): 3070 - 3102

J. M. Rabanel, V. Aoun, I. Elkin, M. Mokhtar and P. Hildgen





Protocatechuic Acid and Human Disease Prevention: Biological Activities and Molecular Mechanisms

, 2012; 19(18): 2901 - 2917

R. Masella, C. Santangelo, M. D’Archivio, G. LiVolti, C. Giovannini and F. Galvano





Iron Chelators for the Treatment of Cancer

, 2012; 19(17): 2689 - 2702

Y. Yu, E. Gutierrez, Z. Kovacevic, F. Saletta, P. Obeidy, Y. Suryo Rahmanto and D. R. Richardson




The Role of microRNAs in Cardiovascular Disease

, 2012; 19(16): 2605 - 2610

N. Papageorgiou, D. Tousoulis, E. Androulakis, G. Siasos, A. Briasoulis, G. Vogiatzi, A.-M. Kampoli, E. Tsiamis, C. Tentolouris and C. Stefanadis




Evaluating Oxidative Stress in Human Cardiovascular Disease: Methodological Aspects and Considerations

, 2012; 19(16): 2504 - 2520

R. Lee, M. Margaritis, K. M. Channon and C. Antoniades




Role of microRNAs in Gynecological Pathology

, 2012; 19(15): 2406 - 2413

J. Gilabert-Estelles, A. Braza-Boils, L. A. Ramon, E. Zorio, P. Medina, F. Espana and A. Estelles




CuAAC Click Chemistry Accelerates the Discovery of Novel Chemical Scaffolds as Promising Protein Tyrosine Phosphatases Inhibitors

, 2012; 19(15): 2399 - 2405

X. -P. He, J. Xie, Y. Tang, J. Li and G. -R. Chen




The Potential of Secondary Metabolites from Plants as Drugs or Leads Against Protozoan Neglected Diseases - Part II

, 2012; 19(14): 2176 - 2228

T.J. Schmidt, S.A. Khalid, A.J. Romanha, T.MA. Alves, M.W. Biavatti, R. Brun, F.B. Da Costa, S.L. de Castro, V.F. Ferreira, M.V.G. de Lacerda, J.H.G. Lago, L.L. Leon, N.P. Lopes, R.C. das Neves Amorim, M. Niehues, I.V. Ogungbe, A.M. Pohlit, M.T. Scotti, W.N. Setzer, M. de N.C. Soeiro and M. Steindel and A.G. Tempone




Anti-Inflammatory Iridoids of Botanical Origin

, 2012; 19(14): 2104 - 2127

A. Viljoen, N. Mncwangi and I. Vermaak





Activity of Epiisopiloturine Against Schistosoma mansoni

, 2012; 19(13): 2051 - 2058

L. M. Veras, M. A. Guimaraes, Y. D. Campelo, M. M. Vieira, C. Nascimento, D. F. Lima, L. Vasconcelos, E. Nakano, S. S. Kuckelhaus, M. C. Batista, J. R. Leite and J. Moraes





Induction of Abscopal Anti-Tumor Immunity and Immunogenic Tumor Cell Death by Ionizing Irradiation - Implications for Cancer Therapies

, 2012; 19(12): 1751 - 1764

B. Frey, Y. Rubner, R. Wunderlich, E.-M. Weiss, A.G. Pockley, R. Fietkau and U.S. Gaipl





In Vitro - In Vivo Correlation of Gene Expression Alterations Induced by Liver Carcinogens

, 2012; 19(11): 1721 - 1730

T. Heise, M. Schug, D. Storm, H. Ellinger-Ziegelbauer, H. J. Ahr, B. Hellwig, J. Rahnenführer, A. Ghallab, G. Guenther, J. Sisnaiske, R. Reif, P. Godoy, H. Mielke, U. Gundert-Remy, A. Lampen, A. Oberemm and J. G. Hengstler





Granulocytes in Helminth Infection - Who is Calling the Shots?

, 2012; 19(10): 1567 - 1586

B. L. Makepeace, C. Martin, J. D. Turner and S. Specht





Leishmaniasis: Prevention, Parasite Detection and Treatment

, 2012; 19(10): 1443 - 1474

T. Kobets, I. Grekov and M. Lipoldova





The Role of Glutamate Signaling in Pain Processes and its Regulation by GCP II Inhibition

, 2012; 19(9): 1323 - 1334

K. M. Wozniak, C. Rojas, Y. Wu Wu and B. S. Slusher





Action of Molecular Switches in GPCRs - Theoretical and Experimental Studies

, 2012; 19(8): 1090 - 1109

B. Trzaskowski, D. Latek, S. Yuan, U. Ghoshdastider, A. Debinski and S. Filipek




Sorafenib (BAY 43-9006) in Hepatocellular Carcinoma Patients: From Discovery to Clinical Development

, 2012; 19(7): 938 - 944

G. Ranieri, G. Gadaleta-Caldarola, V. Goffredo, R. Patruno, A. Mangia, A. Rizzo, R. L. Sciorsci and C. D. Gadaleta




Pharmacological Strategies to Overcome HER2 Cross-Talk and Trastuzumab Resistance

, 2012; 19(7): 1065 - 1075

R. Nahta





Non Polymeric Nanoparticles for Photodynamic Therapy Applications: Recent Developments

, 2012; 19(6): 781 - 792

R. Chouikrat, A. Seve, R. Vanderesse, H. Benachour, M. Barberi-Heyob, S. Richeter, L. Raehm, J.-O. Durand, M. Verelst and C. Frochot





Targeting SKCa Channels in Cancer: Potential New Therapeutic Approaches

, 2012; 19(5): 697 - 713

A. Girault, J.-P. Haelters, M. Potier-Cartereau, A. Chantome, P.-A. Jaffres, P. Bougnoux, V. Joulin and C. Vandier





Multi-Targeted Histone Deacetylase Inhibitors in Cancer Therapy

, 2012; 19(4): 475 - 487

T. Ai, H. Cui and L. Chen





GPCR Heteromers and their Allosteric Receptor-Receptor Interactions

, 2012; 19(3): 356 - 363

K. Fuxe, D. O. Borroto-Escuela, D. Marcellino, W. Romero-Fernandez, M. Frankowska, D. Guidolin, M. Filip, L. Ferraro, A.S. Woods, A. Tarakanov, F. Ciruela, L. F. Agnati and S. Tanganelli





Nonviral Approach for Targeted Nucleic Acid Delivery

, 2012; 19(2): 197 - 208

M. Jafari, M. Soltani, S. Naahidi, D. N. Karunaratne and P. Chen





The Emerging Role of Large Immunophilin FK506 Binding Protein 51 in Cancer

, 2011; 18(35): 5424 - 5429

S. Romano, A. Sorrentino, A. L. Di Pace, G. Nappo, C. Mercogliano and M. F. Romano





Progress in the Preclinical Discovery and Clinical Development of Class I and Dual Class I/IV Phosphoinositide 3-Kinase (PI3K) Inhibitors

, 2011; 18(18): 2686 - 2714

S. J. Shuttleworth, F. A. Silva, A. R.L. Cecil, C. D. Tomassi, T. J. Hill, F. I. Raynaud, P. A. Clarke and P. Workman





Computational Insights into Binding of Bisphosphates to Farnesyl Pyrophosphate Synthase

, 2011; 18(2): 220 - 233

K. Ohno, K. Mori, M. Orita and M. Takeuchi





10-20 Joules as a Neuromolecular Quantum in Medicinal Chemistry: An Alternative Approach to Myriad Molecular Pathways?

, 2010; 17(27): 3094 - 3098

M. A. Persinger





Riluzole, Neuroprotection and Amyotrophic Lateral Sclerosis

, 2010; 17(18): 1942 - 1959

B.C. Cheah, S. Vucic, A. V. Krishnan and M.C. Kiernan




How to Recognize and Workaround Pitfalls in QSAR Studies: A Critical Review

, 2009; 16(32): 4297 - 4313

T. Scior, J. L. Medina-Franco, Q.-T. Do, K. Martinez-Mayorga, J. A. Yunes Rojas and P. Bernard




Current Concepts of Mechanisms in Drug-Induced Hepatotoxicity

, 2009; 16(23): 3041 - 3053

Stefan Russmann, Gerd A. Kullak-Ublick and Ignazio Grattagliano




Novel Insights into Adipogenesis from Omics Data

, 2009; 16(23): 2952 - 2964

Andreas Prokesch, Hubert Hackl, Robab Hakim-Weber, Stefan R. Bornstein and Zlatko Trajanoski




Epilepsy, Regulation of Brain Energy Metabolism and Neurotransmission

, 2009; 16(7): 841 - 853

Jean-Francois Cloix and Tobias Hevor





Toward a Molecular Understanding of the Interaction of Dual Specificity Phosphatases with Substrates: Insights from Structure-Based Modeling and High Throughput Screening

, 2008; 15(25): 2536 - 2544

Ahmet Bakan, John S. Lazo, Peter Wipf, Kay M. Brummond and Ivet Bahar




Human Endotoxemia as a Model of Systemic Inflammation

, 2008; 15(17): 1697 - 1705

A. S. Andreasen, K. S. Krabbe, R. Krogh-Madsen, S. Taudorf, B. K. Pedersen and K. Moller




How Insulin Receptor Substrate Proteins Regulate the Metabolic Capacity of the Liver - Implications for Health and Disease

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