Bentham Science Logo

Track Your Manuscript:


Current Medicinal Chemistry

Volume 27, 42 Issues, 2020
ISSN: 1875-533X (Online)
ISSN: 0929-8673 (Print)
This journal supports open access

Ranking and Category

  • 91st of 298 in

    Biochemistry & Molecular Biology

  • 12th of 61 in

    Chemistry, Medicinal

  • 55th of 267 in

    Pharmacology & Pharmacy

Order Your Article Before Print

Articles Ahead of Print






A Comprehensive Review on Oxysterols and Related Diseases


Afshin Samadi, Suna Sabuncuoglu, Mahshid Samadi, Selen Yilmaz Isikhan, Incilay Lay, Ahmet Yalcinkaya, Salvatore Chirumbolo, Geir Bjørklund* and Massimiliano Peana


DOI: 10.2174/0929867327666200316142659
View Abstract View on PubMed


The Role of Ubiquitin E3 Ligase in Atherosclerosis


Zhi-Xiang Zhou, Zhong Ren, Bin-Jie Yan, Shun-Lin Qu, Zhi-Han Tang , Dang-Heng Wei, Lu-Shan Liu, Min-Gui Fu and Zhi-Sheng Jiang*


DOI: 10.2174/0929867327666200306124418
View Abstract View on PubMed



The Efficacy of Anti-inflammatory Agents in the Prevention of Atrial Fibrillation Recurrences


Homa Nomani, Sara Saei, Thomas P. Johnston, Amirhossein Sahebkar* and Amir Hooshang Mohammadpour


DOI: 10.2174/1389450121666200302095103
View Abstract View on PubMed


Recent Advances in c-Jun N-terminal Kinase (JNK) Inhibitors


Gang Li, Wenqing Qi, Xiaoxun Li, Jinwu Zhao, Meihua Luo and Jianjun Chen*


DOI: 10.2174/0929867327666200210144114
View Abstract View on PubMed




The Effect of CB1 Antagonism on Hepatic Oxidative/Nitrosative Stress and Inflammation in Nonalcoholic Fatty Liver Disease


Bojan Jorgačević, Danijela Vučević, Janko Samardžić, Dušan Mladenović, Milena Vesković, Dušan Vukićević, Rada Ješić and Tatjana Radosavljević*


DOI: 10.2174/0929867327666200303122734
View Abstract View on PubMed



The Role of Matrix Gla Protein (MGP) in Vascular Calcification


Geir Bjorklund*, Erik Svanberg, Maryam Dadar, David J. Card, Salvatore Chirumbolo, Dominic J. Harrington and Jan Aaseth


DOI: 10.2174/0929867325666180716104159
View Abstract View on PubMed


Recent Advances in the Development of Broad-Spectrum Antiprotozoal Agents


Antonio Moreno-Herrera, Sandra Cortez-Maya, Virgilio Bocanegra-Garcia, Bimal Krishna Banik and Gildardo Rivera*


DOI: 10.2174/0929867327666200303170000
View Abstract View on PubMed



The Emerging Role of Atrial Natriuretic Peptide in Psychiatry


Donatella Marazziti, Filippo Maria Barberi, Federico Mucci*, Alessandra Maglio, Valerio Dell’Oste and Liliana Dell’Osso


DOI: 10.2174/0929867327666200219091102
View Abstract View on PubMed


Specialized Diet Therapies: Exploration for Improving Behavior in Autism Spectrum Disorder (ASD)


Geir Bjørklund*, Nagwa A. Meguid, Maryam Dadar, Lyudmila Pivina, Joanna Kałużna-Czaplińska, Jagoda Jóźwik-Pruska, Jan Aaseth, Max Stanley Chartrand, Mostafa I. Waly, Yahya Al-Farsi, Md. Mostafizur Rahman, Joeri J. Pen and Salvatore Chirumbolo


DOI: 10.2174/0929867327666200217101908
View Abstract View on PubMed


Metabolic and Amino Acid Alterations of the Tumor Microenvironment


Petr Stepka, Vit Vsiansky, Martina Raudenska, Jaromir Gumulec, Vojtech Adam and Michal Masarik*


DOI: 10.2174/0929867327666200207114658
View Abstract View on PubMed





Monoclonal Antibodies: A Prospective and Retrospective View


Jwala Sivaccumar*, Annamaria Sandomenico, Luigi Vitagliano and Menotti Ruvo


DOI: 10.2174/0929867327666200219142231
View Abstract View on PubMed







Critical Review on the Chemical Aspects of Cannabidiol (CBD) and Harmonization of Computational Bioactivity Data


Andrea Mastinu*, Giovanni Ribaudo, Alberto Ongaro, Sara Anna Bonini, Maurizio Memo and Alessandra Gianoncelli


DOI: 10.2174/0929867327666200210144847
View Abstract View on PubMed



Serum Hepcidin, the Hepcidin/Ferritin Ratio and the Risk of Type 2 Diabetes: A Systematic Review and Meta-Analysis


Nahid Karamzad, Aziz Eftekhari, Ahad Ashrafi-Asgarabad, Mark J.M. Sullman, Amirhossein Sahebkar* and Saeid Safiri


DOI: 10.2174/0929867327666200207120158
View Abstract View on PubMed



Joint Application of Magnetic Resonance Imaging and Biochemical Biomarkers in Diagnosis of Multiple Sclerosis


Fatemeh Momeni, Amir B. Ghaemmaghami, Majid Nejati, Mohammad Hossein Pourhanifeh, Laleh Shiri Sichani, Omid Reza Tamtaji, Mohammad Momeni, Alireza Khosravi*, Masoud Etemadifar* and Hamed Mirzaei*


DOI: 10.2174/0929867326666191014162713
View Abstract View on PubMed


Protective Role of Natural Products in Glioblastoma Multiforme: A Focus on Nitric Oxide Pathway


Amir R. Afshari, Hamid Mollazadeh, Elmira Mohtashami, Arash Soltani, Mohammad Soukhtanloo, Azar Hosseini, Mohammad Jalili-Nik, Mohammad Mahdi Vahedi, Mostafa Karimi Roshan and Amirhossein Sahebkar*


DOI: 10.2174/0929867327666200130104757
View Abstract View on PubMed




Nanoparticles in Combating Cancer: Opportunities and Limitations. A Brief Review


Elzbieta Pedziwiatr-Werbicka*, Katarzyna Horodecka, Dzmitry Shcharbin* and Maria Bryszewska


DOI: 10.2174/0929867327666200130101605
View Abstract View on PubMed



Ferroptosis: A Novel Mechanism of Artemisinin and its Derivatives in Cancer Therapy


Shunqin Zhu, Qin Yu, Chunsong Huo, Yuanpeng Li, Linshen He, Botian Ran, Ji Chen, Yonghao Li and Wanhong Liu*


DOI: 10.2174/0929867327666200121124404
View Abstract View on PubMed


Glioblastoma: Prognostic Factors and Predictive Response to Radioand Chemotherapy


Francesco Fiorica*, Maria Colella, Rosaria Taibi, Andrea Bonetti, Jacopo Giuliani, Maria Sole Perone, Sonia Missiroli and Carlotta Giorgi


DOI: 10.2174/0929867327666200131095256
View Abstract View on PubMed



Exosomes and Lung Cancer: Roles in Pathophysiology, Diagnosis and Therapeutic Applications


Atefeh Amiri, Mohammad Hossein Pourhanifeh, Hamid Reza Mirzaei, Javid Sadri Nahand, Mohsen Moghoofei, Roxana Sahebnasagh, Hamed Mirzaei* and Michael R. Hamblin*


DOI: 10.2174/0929867327666200204141952
View Abstract View on PubMed



Monoclonal Antibodies Carried in Drug Delivery Nanosystems as a Strategy for Cancer Treatment


Amanda Letícia Polli Silvestre, João Augusto Oshiro-Júnior*, Camila Garcia, Bruna Ortolani Turco, Joandra Maísa da Silva Leite, Bolivar Ponciano Goulart de Lima Damasceno, Jonas Corsino Maduro Soares and Marlus Chorilli*


DOI: 10.2174/0929867327666200121121409
View Abstract View on PubMed









Is Technical-grade Chlordane an Obesogen?


Juliana F. Silva, Bruno P. Moreira, Luís Rato, Maria de Lourdes Pereira, Pedro F. Oliveira and Marco G. Alves*


DOI: 10.2174/0929867327666200121122208
View Abstract View on PubMed



Insights into RNA-dependent RNA Polymerase Inhibitors as Antiinfluenza Virus Agents


Ilaria Giacchello, Francesca Musumeci*, Ilaria D’Agostino, Chiara Greco, Giancarlo Grossi and Silvia Schenone


DOI: 10.2174/0929867327666200114115632
View Abstract View on PubMed








The Application of Hydrogels Based on Natural Polymers for Tissue Engineering


Yasamin Davatgaran Taghipour, Vahideh Raeisdasteh Hokmabad, Azizeh Rahmani Del Bakhshayesh, Nahideh Asadi, Roya Salehi* and Hamid Tayefi Nasrabadi


DOI: 10.2174/0929867326666190711103956
View Abstract View on PubMed


Cell-derived Microparticles and Acute Coronary Syndromes: Is there a Predictive Role for Microparticles?Cell-derived Microparticles and Acute Coronary Syndromes: Is there a Predictive Role for Microparticles


Effimia Zacharia*, Konstantinos Zacharias, George-Angelo Papamikroulis , Dimitrios Bertsias, Antigoni Miliou, Zoi Pallantza , Nikolaos Papageorgiou and Dimitris Tousoulis


DOI: 10.2174/0929867327666191213104841
View Abstract View on PubMed


Predictive Role of BNP/NT-proBNP in Non-Heart Failure Patients Undergoing Catheter Ablation for Atrial Fibrillation: An Updated Systematic Review


Nikolaos Papageorgiou *, Rui Providência, Debbie Falconer, Tanakal Wongwarawipat, Dimitris Tousoulis, Wei Yao Lim , Anthony W. Chow, Richard Schilling and Pier D. Lambiase


DOI: 10.2174/0929867326666191213095554
View Abstract View on PubMed


Microbiome in Chronic Obstructive Pulmonary Disease: Role of Natural Products Against Microbial Pathogens


Alessia Santoro, Carlo Tomino, Giulia Prinzi*, Vittorio Cardaci, Massimo Fini, Lisa Macera, Patrizia Russo and Fabrizio Maggi


DOI: 10.2174/0929867327666191213110551
View Abstract View on PubMed


3D Culture Modelling: An Emerging Approach for Translational Cancer Research in Sarcomas


Victoria Heredia-Soto, Andrés Redondo, José Juan Pozo Kreilinger, Virginia Martínez-Marín, Alberto Berjón and Marta Mendiola*


DOI: 10.2174/0929867326666191212162102
View Abstract View on PubMed









Radiolabeled Protein-inhibitor Peptides with Rapid Clinical Translation Towards Imaging and Therapy


Guillermina Ferro-Flores*, Blanca Ocampo-García, Myrna Luna Gutiérrez, Clara Santos Cuevas, Nallely Jiménez-Mancilla, Erika Azorín-Vega and Laura Meléndez-Alafort


DOI: 10.2174/0929867327666191223121211
View Abstract View on PubMed



Recent Advances in Multi-target Drugs Targeting Protein Kinases and Histone Deacetylases in Cancer Therapy


Yong Ling*, Ji Liu, Jianqiang Qian, Chi Meng, Jing Guo, Weijie Gao, Biao Xiong, Changchun Ling and Yanan Zhang


DOI: 10.2174/0929867327666200102115720
View Abstract View on PubMed



Effects of Pterostilbene on Diabetes, Liver Steatosis and Serum Lipids


Saioa Gómez-Zorita, Iñaki Milton-Laskíbar, Leixuri Aguirre, Alfredo Fernández-Quintela*, Jianbo Xiao and María P. Portillo


DOI: 10.2174/0929867326666191029112626
View Abstract View on PubMed



Anti-androgen Drugs in the Treatment of Obsessive-compulsive Disorder: A Systematic Review


Homa Nomani, Amir Hooshang Mohammadpour, Seyed Mohammad Hassan Moallem, Mahdi Jannati YazdanAbad, George E. Barreto and Amirhossein Sahebkar*


DOI: 10.2174/0929867326666191209142209
View Abstract View on PubMed



Role of Resveratrol in Modulating microRNAs in Human Diseases: From Cancer to Inflammatory Disorder


Atefeh Amiri, Maryam Mahjoubin Tehran, Zatollah Asemi, Alimohammad Shafiee, Sarah Hajighadimi, Sanaz Moradizarmehri, Hamid Reza Mirzaei* and Hamed Mirzaei*


DOI: 10.2174/0929867326666191212102407
View Abstract View on PubMed


Resveratrol: A New Potential Therapeutic Agent for Melanoma?


Mohamad Hossein Pourhanifeh, Kazem Abbaszadeh-Goudarzi, Mohammad Goodarzi, Sara G.M. Piccirillo, Alimohammad Shafiee, Sarah Hajighadimi, Sanaz Moradizarmehri, Zatollah Asemi* and Hamed Mirzaei*


DOI: 10.2174/0929867326666191212101225
View Abstract View on PubMed


Melanoma: Prognostic Factors and Factors Predictive of Response to Therapy


Martina Strudel, Lucia Festino*, Vito Vanella, Massimiliano Beretta, Francesco M. Marincola and Paolo A. Ascierto


DOI: 10.2174/0929867326666191205160007
View Abstract View on PubMed



The Predictive Role for ST2 in Patients with Acute Coronary Syndromes and Heart Failure


Vasiliki Tsigkou*, Gerasimos Siasos*, Evanthia Bletsa, Maria- Evi Panoilia, Angeliki Papastavrou, Georgios Kokosias, Evangelos Oikonomou, Nikolaos Papageorgiou, Marina Zaromitidou, Georgios Marinos, Manolis Vavuranakis, Christodoulos Stefanadis, Athanasios G. Papavassiliou and Dimitris Tousoulis


DOI: 10.2174/0929867326666191016121630
View Abstract View on PubMed



Gene Expression Assay in the Management of Early Breast Cancer


Roberta Caputo , Daniela Cianniello , Antonio Giordano, Michela Piezzo , Maria Riemma , Marco Trovo , Massimiliano Berretta and Micheline De-Laurentiis *


DOI: 10.2174/0929867326666191205163329
View Abstract View on PubMed


Drug Leads Derived from Japanese Marine Organisms


Daisuke Uemura*, Yoshinori Kawazoe, Toshiyasu Inuzuka, Yuki Itakura, Chiari Kawamata and Takahiro Abe*


DOI: 10.2174/0929867326666191022125851
View Abstract View on PubMed



Electrochemical-Based Biosensors: New Diagnosis Platforms for Cardiovascular Disease


Fatemeh Yousefi, Ahmad Movahedpour, Zahra Shabaninejad, Younes Ghasemi, Shahram Rabbani, Ali Sobnani-Nasab, Soheila Mohammadi, Behzad Hajimoradi, Samaneh Rezaei, Amir Savardashtaki*, Majid Mazoochi* and Hamed Mirzaei*


DOI: 10.2174/0929867326666191024114207
View Abstract View on PubMed




Small Molecules with Anti Prion Activity


Carlo Mustazza*, Marco Sbriccoli, Paola Minosi and Carla Raggi


DOI: 10.2174/0929867326666190927121744
View Abstract View on PubMed




Tubulin Inhibitors Binding to Colchicine-site: A Review from 2015 to 2019


Lin-Ying Xia, Ya-Liang Zhang, Rong Yang, Zhong-Chang Wang, Ya-Dong Lu*, Bao-Zhong Wang* and Hai-Liang Zhu


DOI: 10.2174/0929867326666191003154051
View Abstract View on PubMed




The Beneficial Actions of SGLT-2 Inhibitors Beyond the Management of Hyperglycemia


Charalampos Loutradis, Eirini Papadopoulou, Elena Angeloudi, Asterios Karagiannis and Pantelis Sarafidis*


DOI: 10.2174/0929867326666191029111713
View Abstract View on PubMed










Stem Cell Transplant for Advanced Stage Liver Disorders: Current Scenario and Future Prospects


Anjum Mahmood, Rajasekar Seetharaman, Prashant Kshatriya, Divyang Patel and Anand S. Srivastava*


DOI: 10.2174/0929867326666191004161802
View Abstract View on PubMed





Molecular Markers of Regulatory T Cells in Cancer Immunotherapy with Special Focus on Acute Myeloid Leukemia (AML) - A Systematic Review


Parham Jabbarzadeh Kaboli, Lingling Zhang, Shixin Xiang, Jing Shen, Mingxing Li, Yueshui Zhao, Xu Wu, Qijie Zhao, Hanyu Zhang, Ling Lin, Jianhua Yin, Yuanlin Wu, Lin Wan, Tao Yi, Xiang Li, Chi Hin Cho, Jing Li*, Zhangang Xiao* and Qinglian Wen


DOI: 10.2174/0929867326666191004164041
View Abstract View on PubMed


Discovery and Development of the Oral Complement Factor D Inhibitor ACH-4471


Jason A. Wiles, Manuel D. Galvan, Steven D. Podos, Michael Geffner and Mingjun Huang*


DOI: 10.2174/0929867326666191001130342
View Abstract View on PubMed



Recent Progress of Benzimidazole Hybrids for Anticancer Potential


Md Jawaid Akhtar, M. Shahar Yar*, V. K. Sharma, Ahsan Ahmed Khan, Zulphikar Ali, Md Rafi Haider and Ankita Pathak


DOI: 10.2174/0929867326666190808122929
View Abstract View on PubMed


Secondary Metabolites from Deep-sea Derived Microorganisms


Chunxiao Sun, Shah Mudassir, Zhenzhen Zhang, Yanyan Feng, Yimin Chang, Qian Che, Qianqun Gu, Tianjiao Zhu, Guojian Zhang* and Dehai Li*


DOI: 10.2174/0929867326666190618153950
View Abstract View on PubMed



Mercury Exposure, Epigenetic Alterations, and Brain Tumorigenesis: A Possible Relationship?


Geir Bjørklund*, Lyudmila Pivina, Maryam Dadar, Yuliya Semenova, Salvatore Chirumbolo and Jan Aaseth


DOI: 10.2174/0929867326666190930150159
View Abstract View on PubMed




Role of Exosomes in Photodynamic Anticancer Therapy


Yuan Jiang, Chuanshan Xu*, Wingnang Leung*, Mei Lin, Xiaowen Cai, Huanhuan Guo, Jiyong Zhang and Fanwen Yang


DOI: 10.2174/0929867326666190918122221
View Abstract View on PubMed


Copper Concentrations in Breast Cancer: A Systematic Review and Meta-Analysis


Leila Jouybari, Faezeh Kiani, Farhad Islami, Akram Sanagoo*, Fatemeh Sayehmiri, Bozena Hosnedlova, Monica Daniela Doşa, Rene Kizek, Salvatore Chirumbolo and Geir Bjørklund*


DOI: 10.2174/0929867326666190918120209
View Abstract View on PubMed



Translational Theragnostic of Ovarian Cancer: where do we stand?


Maria Grazia Perrone, Oreste Luisi, Anna De Grassi, Savina Ferorelli, Gennaro Cormio and Antonio Scilimati*


DOI: 10.2174/0929867326666190816232330
View Abstract View on PubMed


Chemical Mediators’ Expression Associated with the Modulation of Pain in Rheumatoid Arthritis


Cortes-Altamirano J. L., Morraz-Varela A., Reyes-Long S., Gutierrez M., Cindy Bandala, Clavijo-Cornejo D. and Alfaro-Rodriguez A.*


DOI: 10.2174/0929867326666190816225348
View Abstract View on PubMed





The Role of Zinc and Copper in Insulin Resistance and Diabetes Mellitus


Geir Bjørklund*, Maryam Dadar, Lyudmila Pivina, Monica Daniela Doşa, Yuliya Semenova and Jan Aaseth


DOI: 10.2174/0929867326666190902122155
View Abstract View on PubMed




The Disposal of Reactive Carbonyl Species through Carnosine Conjugation. What We Know Now


Ettore Gilardoni, Giovanna Baron, Alessandra Altomare, Marina Carini, Giancarlo Aldini and Luca Regazzoni*


DOI: 10.2174/0929867326666190624094813
View Abstract View on PubMed



Metastatic Colorectal Cancer: Prognostic and Predictive Factors


Anna Nappi*, Guglielmo Nasti, Carmela Romano, Massimiliano Berretta and Alessandro Ottaiano


DOI: 10.2174/0929867326666190620110732
View Abstract View on PubMed



VSPrep: A KNIME Workflow for the Preparation of Molecular Databases for Virtual Screening


José-Manuel Gally, Stéphane Bourg, Jade Fogha, Quoc-Tuan Do, Samia Aci-Sèche and Pascal Bonnet


DOI: 10.2174/0929867326666190614160451
View Abstract View on PubMed




Redox Regulation in the Base Excision Repair Pathway: Old and New Players as Cancer Therapeutic Targets


Aleksandra Rajapakse, Amila Suraweera, Didier Boucher, Ali Naqi, Kenneth O'Byrne, Derek John Richard and Laura Vanda Croft*


DOI: 10.2174/0929867326666190430092732
View Abstract View on PubMed


Circulating Biomarkers for Response Prediction of Rectal Cancer to Neoadjuvant Chemoradiotherapy


Chiara Bedin*, Sara Crotti, Edoardo D`Angelo, Sara D`Aronco, Salvatore Pucciarelli and Marco Agostini


DOI: 10.2174/0929867326666190507084839
View Abstract View on PubMed




Parthenolide and Its Analogues: A New Potential Strategy for the Treatment of Triple-Negative Breast Tumors


Thaise Gonçalves Araújo*, Lara Vecchi, Paula Marynella Alves Pereira Lima, Everton Allan Ferreira, Igor Moreira Campos, Douglas Cardoso Brandão, Gabriela Silva Guimarães, Matheus Alves Ribeiro and Ademar Alves da Silva Filho


DOI: 10.2174/0929867326666190816230121
View Abstract View on PubMed


Inflammation as the Common Biological Link Between Depression and Cardiovascular Diseases: Can Carnosine Exert a Protective Role?


Giuseppe Caruso*, Claudia G. Fresta, Margherita Grasso, Rosa Santangelo, Giuseppe Lazzarino, Susan M. Lunte and Filippo Caraci


DOI: 10.2174/0929867326666190712091515
View Abstract View on PubMed


The Design and Application of Nanomaterials as Drug Carriers in Cancer Treatment


Jia Hou, Xiaoyan Sun, Ying Huang, Shaohua Yang, Junjie Liu, Changhao Feng, Jun Ma and Bin Chen*


DOI: 10.2174/0929867326666190816231409
View Abstract View on PubMed






Metal Complexes As Promising Agents for Biomedical Applications


Natalia V. Loginova*, Hleb I. Harbatsevich, Nikolai P. Osipovich, Galina A. Ksendzova, Tatsiana V. Koval’chuk and Genrikh I. Polozov


DOI: 10.2174/0929867326666190417143533
View Abstract View on PubMed



In Vitro Immunodetection of Prothymosin Alpha in Normal and Pathological Conditions


Chrysoula-Evangelia Karachaliou, Hubert Kalbacher, Wolfgang Voelter, Ourania E. Tsitsilonis and Evangelia Livaniou*


DOI: 10.2174/0929867326666190807145212
View Abstract View on PubMed



Harmonious Biomaterials for Development of In situ Approaches for Locoregional Delivery of Anti-cancer Drugs: Current Trends


Amrinder Singh, Shubham Thakur, Tushit Sharma, Manjot Kaur, Nikhil Shri Sahajpal, Rohan Aurora and Subheet Kumar Jain*


DOI: 10.2174/1573406415666190621095726
View Abstract View on PubMed




Formulating SLN and NLC as Innovative Drug Delivery Systems for Non-Invasive Routes of Drug Administration


Bruno Fonseca-Santos, Patrícia Bento Silva, Roberta Balasin Rigon, Mariana Rillo Sato and Marlus Chorilli*


DOI: 10.2174/0929867326666190624155938
View Abstract View on PubMed




Microbiota, Immune System and Autism Spectrum Disorders. An Integrative Model towards Novel Treatment Options


Barbara Carpita, Donatella Marazziti*, Lionella Palego, Gino Giannaccini, Laura Betti and Liliana Dell'Osso


DOI: 10.2174/0929867326666190328151539
View Abstract










Discovery of Dengue Virus Inhibitors


Adib Afandi Abdullah, Yean Kee Lee, Sek Peng Chin, See Khai Lim, Vannajan Lee, Rozana Othman, Shatrah Othman, Noorsaadah Abdul Rahman, Rohana Yusof and Choon Han Heh*


DOI: 10.2174/0929867326666181204155336
View Abstract View on PubMed



Immune-Based Therapies for Traumatic Brain Injury: Insights from Pre-Clinical Studies


Caroline Amaral Machado, Ana Cristina Simões e Silva*, Amanda Silva de Miranda, Thiago Macedo e Cordeiro, Rodrigo Novaes Ferreira, Leonardo Cruz de Souza, Antônio Lúcio Teixeira and Aline Silva de Miranda


DOI: 10.2174/0929867326666190710173234
View Abstract View on PubMed




Discovery and Development of Cyclin-Dependent Kinase 8 Inhibitors


Xiao Lv, Yongbing Tian, Shiyu Li, Kai Cheng, Xufeng Huang, Haiyan Kong, Chenzhong Liao and Zhouling Xie*


DOI: 10.2174/0929867326666190402110528
View Abstract View on PubMed





Insights on Nutrients as Analgesics in Chronic Pain


Geir Bjørklund*, Salvatore Chirumbolo, Maryam Dadar, Joeri J. Pen, Monica Daniela Doşa, Lyudmila Pivina, Yulia Semenova and Jan Aaseth


DOI: 10.2174/0929867326666190712172015
View Abstract View on PubMed


Histone Deacetylases (HDACs) in Gastric Cancer: An Update of Their Emerging Prognostic and Therapeutic Role


Dimitrios Schizas, Aikaterini Mastoraki, Leon Naar, Diamantis I Tsilimigras*, Ioannis Katsaros, Vasiliki Fragkiadaki, Georgia-Sofia Karachaliou, Nikolaos Arkadopoulos, Theodore Liakakos and Dimitrios Moris


DOI: 10.2174/0929867326666190712160842
View Abstract View on PubMed


Targeting Mitochondria Through the Use of Mitocans as Emerging Anticancer Agents


Ioana Macasoi, Alexandra Mioc*, Marius Mioc*, Irina Soica, Adelina Chevereșan, Cristina Dehelean and Victor Dumitrașcu


DOI: 10.2174/0929867326666190712150638
View Abstract View on PubMed




Recent Development on Anti-Obesity Compounds and their Mechanisms of Action: A Review


Yixing Qiu, Huanghe Yu , Rong Zeng, Shiyin Guo, Muhammad Daniyal, Zeyu Deng, Aibing Wang and Wei Wang*


DOI: 10.2174/0929867326666190215114359
View Abstract View on PubMed


Biomarkers, Biosensors and Biomedicine


Weslley Felix de Oliveira, Priscila Marcelino dos Santos Silva, Luana Cassandra Breitenbach Barroso Coelho and Maria Tereza dos Santos Correia*


DOI: 10.2174/0929867326666190124103125
View Abstract View on PubMed


Recent Advances in Spontaneous Raman Spectroscopic Imaging: Instrumentation and Applications


Nan Wang, Honghao Cao, Lin Wang, Feng Ren, Qi Zeng, Xinyi Xu, Jimin Liang, Yonghua Zhan and Xueli Chen*


DOI: 10.2174/0929867326666190619114431
View Abstract View on PubMed









Protein Microarrays: Valuable Tools for Ocular Diseases Research


María Garranzo-Asensio, Ana Montero-Calle, Guillermo Solís-Fernández, Rodrigo Barderas and Ana Guzman-Aranguez*


DOI: 10.2174/0929867326666190627131300
View Abstract View on PubMed


Autoimmune Hepatitis and Stellate Cells; an Insight into the Role of Autophagy


Shahram Golbabapour, Kamran Bagheri-Lankarani, Saeid Ghavami and Bita Geramizadeh*


DOI: 10.2174/0929867326666190402120231
View Abstract View on PubMed






Differential Characteristics of HMGB2 Versus HMGB1 and their Perspectives in Ovary and Prostate Cancer


María Cámara-Quílez, Aida Barreiro-Alonso, Esther Rodríguez-Bemonte, María Quindós-Varela, Esperanza Cerdán and Mónica Lamas-Maceiras*


DOI: 10.2174/0929867326666190123120338
View Abstract View on PubMed












Anthocyanins As Modulators of Cell Redox-Dependent Pathways in Non-Communicable Diseases


Antonio Speciale, Antonella Saija, Romina Bashllari, Maria Sofia Molonia, Claudia Muscara, Cristina Occhiuto, Francesco Cimino* and Mariateresa Cristani


DOI: 10.2174/0929867325666181112093336
View Abstract View on PubMed





B7-H3 Immune Checkpoint Protein in Human Cancer


Karine Flem-Karlsen, Oystein Fodstad and Caroline E. Nunes-Xavier*


DOI: 10.2174/0929867326666190517115515
View Abstract View on PubMed



Reversine: A Synthetic Purine with a Dual Activity as a Cell Dedifferentiating Agent and a Selective Anticancer Drug


Marco Piccoli, Andrea Ghiroldi, Michelle M. Monasky, Federica Cirillo, Giuseppe Ciconte, Carlo Pappone and Luigi Anastasia*


DOI: 10.2174/0929867326666190103120725
View Abstract View on PubMed


Structure and Function of L,D- and D,D-transpeptidase Family Enzymes from Mycobacterium tuberculosis


Gideon F. Tolufashe, Victor T. Sabe, Colins U. Ibeji, Thandokuhle Ntombela, Thavendran Govender, Glenn E. M. Maguire, Hendrik G. Kruger, Gyanu Lamichhane and Bahareh Honarparvar*


DOI: 10.2174/0929867326666181203150231
View Abstract View on PubMed



Quaternized Chitosan Nanoparticles in Vaccine Applications


Shuang Yu , Shengnan Hao, Beini Sun , Dongying Zhao , Xingye Yan and Kai Zhao*


DOI: 10.2174/0929867326666190227192527
View Abstract View on PubMed



Metabolic Reprogramming of Cancer by Chemicals that Target Glutaminase Isoenzymes


José M. Matés*, José A. Campos-Sandoval, Juan de los Santos-Jiménez, Juan A. Segura, Francisco J. Alonso and Javier Márquez


DOI: 10.2174/0929867326666190416165004
View Abstract View on PubMed




Recent Advances of Chitosan and Its Derivatives in Biomedical Applications


Fei Ding, Jiawei Fu, Chuang Tao, Yanhua Yu, Xianran He, Yangguang Gao and Yongmin Zhang*


DOI: 10.2174/0929867326666190405151538
View Abstract View on PubMed



Therapeutic applications of Peptides Against Zika Virus: A Review


Preeti Karwal, Ishwar Dutt Vats, Niharika Sinha, Anchal Singhal, Teena Sehgal and Pratibha Kumari*


DOI: 10.2174/0929867326666190111115132
View Abstract View on PubMed


Novel Vaccine Candidates against Tuberculosis


Zhihao Li, Changping Zheng, Marco Terreni, Lisa Tanzi, Matthieu Sollogoub and Yongmin Zhang*


DOI: 10.2174/0929867326666181126112124
View Abstract View on PubMed



Targeting n-3 Polyunsaturated Fatty Acids in Non-alcoholic Fatty Liver Disease


Rodrigo Valenzuela*, Macarena Ortiz, María Catalina Hernández-Rodas, Francisca Echeverría and Luis A. Videla


DOI: 10.2174/0929867326666190410121716
View Abstract View on PubMed



Mechanistic Insights of Chemicals and Drugs as Risk Factors for Systemic Lupus Erythematosus


Qingjun Pan*, Yun Guo*, Linjie Guo*, Shuzhen Liao, Chunfei Zhao, Sijie Wang and Hua-feng Liu


DOI: 10.2174/0929867326666190404140658
View Abstract View on PubMed



From Recognition to Reaction Mechanism: An Overview on the Interactions between HIV-1 Protease and its Natural Targets


Monsurat M. Lawal, Zainab K. Sanusi, Thavendran Govender, Glenn E. M. Maguire, Bahareh Honarparvar and Hendrik G. Kruger*


DOI: 10.2174/0929867325666181113122900
View Abstract View on PubMed


Structural Basis of Drug Recognition by Human Serum Albumin


Loris Leboffe, Alessandra di Masi*, Fabio Polticelli, Viviana Trezza and Paolo Ascenzi


DOI: 10.2174/0929867326666190320105316
View Abstract View on PubMed



Anesthetic-induced Myocardial Conditioning: Molecular Fundamentals and Scope


Jose Luis Guerrero Orriach*, Juan Jose Escalona Belmonte , Marta Ramirez-Aliaga, Alicia Ramirez-Fernandez , Aida Raigon-Ponferrada , Manuel Rubio-Navarro and Jose Cruz-Manas


DOI: 10.2174/0929867325666180926161427
View Abstract View on PubMed



B7-H3-targeted Radioimmunotherapy of Human Cancer


Benjamin B. Kasten, Soldano Ferrone, Kurt R. Zinn and Donald J. Buchsbaum*


DOI: 10.2174/0929867326666190228120908
View Abstract View on PubMed




Metabolomic Biomarkers in Gynecology: A Treasure Path or a False Path?


Igor Govorov , Stanislav Sitkin , Tatyana Pervunina , Alexey Moskvin , Denis Baranenko and Eduard Komlichenko


DOI: 10.2174/0929867326666190104124245
View Abstract View on PubMed




Exosome-like Nanoparticles: A New Type of Nanocarrier


Mário Fernandes, Ivo Lopes, José Teixeira, Cláudia Botelho and Andreia C. Gomes*


DOI: 10.2174/0929867326666190129142604
View Abstract View on PubMed





Oxidative Status in Multiple Sclerosis and Off-Targets of Antioxidants: The Case of Edaravone


Cristina Agresti, Rosella Mechelli, Stefania Olla, Caterina Veroni, Cecilia Eleuteri, Giovanni Ristori and Marco Salvetti*


DOI: 10.2174/0929867326666190124122752
View Abstract View on PubMed








The Role of Mitochondria in Systemic Lupus Erythematosus: A Glimpse of Various Pathogenetic Mechanisms


Shi-kun Yang, Hao-ran Zhang, Shu-peng Shi, Ying-qiu Zhu, Na Song, Qing Dai, Wei Zhang, Ming Gui and Hao Zhang*


DOI: 10.2174/0929867326666181126165139
View Abstract View on PubMed




Recent Advances and Challenges of the Drugs Acting on Monoamine Transporters


Weiwei Xue*, Tingting Fu, Guoxun Zheng, Gao Tu, Yang Zhang, Fengyuan Yang, Lin Tao, Lixia Yao and Feng Zhu*


DOI: 10.2174/0929867325666181009123218
View Abstract View on PubMed


An Update on the Neurochemistry of Essential Tremor


Félix Javier Jiménez-Jiménez *, Hortensia Alonso-Navarro, Elena García-Martín and José A.G. Agúndez


DOI: 10.2174/0929867325666181112094330
View Abstract View on PubMed





Stimuli-responsive Drug Delivery Nanocarriers in the Treatment of Breast Cancer


Joao A. Oshiro-Junior , Renata Carolina Alves, Gilmar Hanck-Silva , Mariana R. Sato, Camila Rodero, Josimar O. Eloy* and Marlus Chorilli*


DOI: 10.2174/0929867325666181009120610
View Abstract View on PubMed




Manipulation of the Immune System for Cancer Defeat: A Focus on the T Cell Inhibitory Checkpoint Molecules


Paolo D’Arrigo, Martina Tufano, Anna Rea, Vincenza Vigorito, Nunzia Novizio, Salvatore Russo, Maria Fiammetta Romano and Simona Romano*


DOI: 10.2174/0929867325666181106114421
View Abstract View on PubMed


Development of Pin1 Inhibitors and their Potential as Therapeutic Agents


Yusuke Nakatsu, Yasuka Matsunaga, Koji Ueda, Takeshi Yamamotoya, Yuki Inoue, Masa-ki Inoue, Yu Mizuno, Akifumi Kushiyama, Hiraku Ono, Midori Fujishiro, Hisanaka Ito, Takayoshi Okabe and Tomoichiro Asano*


DOI: 10.2174/0929867325666181105120911
View Abstract View on PubMed



Aptamer-Based Targeted Drug Delivery Systems: Current Potential and Challenges


Fen He, Nachuan Wen, Daipeng Xiao, Jianhua Yan, Hongjie Xiong, Shundong Cai, Zhenbao Liu* and Yanfei Liu*


DOI: 10.2174/0929867325666181008142831
View Abstract View on PubMed


Antimicrobial Capacity of Plant Polyphenols against Gram-positive Bacteria: A Comprehensive Review


Francisco Javier Alvarez-Martinez, Enrique Barrajon-Catalan*, Jose Antonio Encinar, Juan Carlos Rodriguez-Diaz and Vicente Micol


DOI: 10.2174/0929867325666181008115650
View Abstract View on PubMed


The Close Interplay of Nitro-Oxidative Stress, Advanced Glycation end Products and Inflammation in Inflammatory Bowel Diseases


Fabiana Andrea Moura, Marília Oliveira Fonseca Goulart*, Amylly Sanuelly da Paz Martins and Samara Bonfim Gomes Campos


DOI: 10.2174/0929867325666180904115633
View Abstract View on PubMed




Metabolomics of Exhaled Breath Condensate by Nuclear Magnetic Resonance Spectroscopy and Mass Spectrometry: A Methodological Approach


Mauro Maniscalco*, Adele Cutignano, Debora Paris, Dominique J. Melck, Antonio Molino, Salvatore Fuschillo and Andrea Motta*


DOI: 10.2174/0929867325666181008122749
View Abstract View on PubMed



Recent Progress in Histone Deacetylase Inhibitors as Anticancer Agents


Loredana Cappellacci*, Diego R. Perinelli, Filippo Maggi, Mario Grifantini and Riccardo Petrelli*


DOI: 10.2174/0929867325666181016163110
View Abstract View on PubMed





The Healing Effects of Spices in Chronic Diseases


Danka Bukvicki*, Davide Gottardi, Sahdeo Prasad, Miroslav Novakovic, Petar Marin and Amit Kumar Tyagi


DOI: 10.2174/0929867325666180831145800
View Abstract View on PubMed


Circulating Biomarkers for Tumor Angiogenesis: Where Are We?


Virginia Di Paolo, Marta Colletti, Valentina Ferruzzi, Ida Russo, Angela Galardi, Iside Alessi , Giuseppe Maria Milano and Angela Di Giannatale*


DOI: 10.2174/0929867325666180821151409
View Abstract View on PubMed


Xanthine Derivatives as Agents Affecting Non-dopaminergic Neuroprotection in Parkinson`s Disease


Alexandra Kasabova-Angelova, Diana Tzankova, Javor Mitkov, Maya Georgieva, Virginia Tzankova, Alexander Zlatkov and Magdalena Kondeva-Burdina*


DOI: 10.2174/0929867325666180821153316
View Abstract View on PubMed





The Role of Diet-Related Short-Chain Fatty Acids in Colorectal Cancer Metabolism and Survival: Prevention and Therapeutic Implications


Sara Daniela Gomes, Claudia Suellen Oliveira, Joao Azevedo-Silva, Marta Casanova, Judite Barreto, Helena Pereira, Susana Chaves, Ligia Rodrigues, Margarida Casal, Manuela Corte-Real, Fatima Baltazar and Ana Preto*


DOI: 10.2174/0929867325666180530102050
View Abstract View on PubMed










Acyclovir in the Treatment of Herpes Viruses – A Review


Katarzyna Klysik, Aneta Pietraszek, Anna Karewicz and Maria Nowakowska*


DOI: 10.2174/0929867325666180309105519
View Abstract View on PubMed




Editor-in-Chief

Atta-ur-Rahman, FRS
(25732 citations)
Honorary Life Fellow
Kings College
University of Cambridge
Cambridge
UK

Biography View Full Editorial Board

Journal History

Current Medicinal Chemistry was introduced in 1994 with the assistance of Dr. Atta-ur-Rahman, who is the current Editor-in-Chief serving since 1994.
Scopus CiteScore Metrics: 3.61

Advertisement

Coronaviruses-JOIN-EDITORIAL-BOARDNational-Endometriosis-Awareness MonthNational Colorectal Cancer Awareness Month Multiple Myeloma Awareness MonthBrain Injury Awareness Month

Related Journals

Related eBooks

eBooks Catalog