Bentham Science Logo

Track Your Manuscript:


Current Medicinal Chemistry

Volume 28, 42 Issues, 2021
ISSN: 1875-533X (Online)
ISSN: 0929-8673 (Print)
This journal supports open access

Articles Ahead of Print

Renin-Angiotensin System in Central Nervous System Diseases and its Interaction with COVID-19


Katharina Lanza, Raphael Dias, Rafaela dos Santos Oliveira, Luís Belotto, Aline Silva Miranda and Ana Cristina Simões e Silva*


DOI: 10.2174/0929867328666210212101854
View Abstract View on PubMed


Protective Effects of Curcumin Against Lipopolysaccharide-Induced Toxicity


Ali Ganji, Iman Farahani, Amir Mohammad Saeedifar, Ghasem Mosayebi, Ali Ghazavi, Muhammed Majeed, Tannaz Jamialahmadi and Amirhossein Sahebkar*


DOI: 10.2174/0929867328666210525124707
View Abstract View on PubMed









Challenges and Perspectives in the Discovery of Dengue Virus Entry Inhibitors


Facundo N. Gallo, Ana G. Enderle, Lucas A. Pardo, Emilse S. Leal and Mariela Bollini*


DOI: 10.2174/0929867328666210521213118
View Abstract View on PubMed


The Emerging Landscapes to Drug Delivery Systems for the Treatment of Pancreatic Cancer


Agnes Magri*, Franciele Garcia Baveloni, Bruna Almeida Furquim de Camargo and Marlus Chorilli*


DOI: 10.2174/0929867328666210319144347
View Abstract View on PubMed



Recent Advances in Chalcone-Based Anticancer Heterocycles: A Structural and Molecular Target Perspective


Vishal Kumar, Sanjeev Dhawan, Pankaj Sanjay Girase, Paul Awolade, Suraj Raosaheb Shinde, Rajshekhar Karpoormath* and Parvesh Singh*


DOI: 10.2174/0929867328666210322102836
View Abstract View on PubMed





A Review of Light Sources and Enhanced Targeting for Photodynamic Therapy


Menghua Xiang, Quanming Zhou, Zihan Shi, Xuan Wang, Mengchu Li, Yan Jia, Shaoyun Li, Fen Yang, Wei Wang, Tongkai Chen, Xiaojun Xu, Bigyan Sharma, Yichu Nie, Qicai Xiao* and Liqian Gao*


DOI: 10.2174/0929867328666210121122106
View Abstract View on PubMed



Current Phthalocyanines Delivery Systems in Photodynamic Therapy: An Updated Review


Mariana Miretti*, Cesar German Prucca, Tomas Cristian Tempesti and Maria Teresa Baumgartner*


DOI: 10.2174/0929867328666210208111234
View Abstract View on PubMed


The Application of Cell-Penetrating-Peptides in Antibacterial Agents


Hangfei Chen, Dheerendranath Battalapalli, Mohamed S. Draz, Pengfei Zhang* and Zhi Ruan*


DOI: 10.2174/0929867328666210322162809
View Abstract



Impact of Curcumin on Microsomal Enzyme Activities: Drug Interaction and Chemopreventive Studies


Habibeh Mashayekhi-Sardoo, Adeleh Mashayekhi‐Sardoo, Basil D. Roufogalis, Tannaz Jamialahmadi and Amirhossein Sahebkar*


DOI: 10.2174/0929867328666210329123449
View Abstract View on PubMed



Algae as a Source of Bioactive Compounds to Prevent the Development of Type 2 Diabetes Mellitus


Jelena B. Popović-Djordjević, Jelena S. Katanić Stanković, Vladimir Mihailović, Antia G. Pereira, Paula Garcia-Oliveira, Miguel A. Prieto and Jesus Simal-Gandara*


DOI: 10.2174/0929867328666210325100654
View Abstract View on PubMed


ICP-MS-based Approach to Determine Nanoparticle Recovery After Hollow Fiber Flow Field Flow Fractionation


Fabian L. Kriegel, Benjamin C. Krause, Yves U. Hachenberger*, Rafael Fister, Philipp Reichardt, Jutta Tentschert, Ajay-Vikram Singh*, Harald Jungnickel, Peter Laux and Andreas Luch


DOI: 10.2174/0929867328666210222094913
View Abstract View on PubMed


Current Trends in the Therapeutic Strategies for Diabetes Management


Ponnurengam Malliappan Sivakumar, Veluchamy Prabhawathi, Ali Zarrabi, Sohail Akthar and Pranav Kumar Prabhakar*


DOI: 10.2174/0929867328666210218183914
View Abstract View on PubMed


Small-molecule Inhibitors of HIV-1 Reverse Transcriptase-Associated Ribonuclease H Function: Challenges and Recent Developments


Valentina Noemi Madia, Antonella Messorea, Alessandro De Leo, Valeria Tudino, Ivano Pindinello, Francesco Saccoliti, Daniela De Vita, Luigi Scipione, Roberta Costi* and Roberto Di Santoa


DOI: 10.2174/0929867328666210322164557
View Abstract


Overview of PCTK3/CDK18: A Cyclin-Dependent Kinase Involved in Specific Functions in Post-Mitotic Cells


Rebeka de Oliveir Pepino, Fernanda Coelho, Tatiane Aparecida Buzanello Janku, Diandra Pinheiro Alencar, Walter Figueira de Azevedo Jr* and Fernanda Canduri*


DOI: 10.2174/0929867328666210329122147
View Abstract View on PubMed



Phenolic Compounds in Prevention and Treatment of Skin Cancers: A Review


Francesca Gado, Maria Digiacomo*, Jasmine Esposito Salsano, Marco Macchia and Clementina Manera


DOI: 10.2174/0929867328666210324160324
View Abstract View on PubMed


Therapeutic Potential of Natural Compounds in Lung Cancer


Minnatallah Al-Yozbaki, Peter J. Wilkin, Girish Kumar Gupta and Cornelia M. Wilson*


DOI: 10.2174/0929867328666210322103906
View Abstract View on PubMed


Nanomedical Applications of Amphiphilic Dendrimeric Micelles


Guillermo Leobardo Rodríguez-Acosta, Carlos Hernández-Montalbán, María Fernanda Sabrina Vega-Razo, Irving Osiel Castillo-Rodríguez and Marcos Martínez-García*


DOI: 10.2174/0929867328666210329125601
View Abstract View on PubMed



The Use of L-Glucose in Cancer Diagnosis: Results from In Vitro and In Vivo Studies


Ioanna A. Anastasiou*, Ioanna Eleftheriadou, Anastasios Tentolouris, Iordanis Mourouzis, Constantinos Pantos and Nikolaos Tentolouris*


DOI: 10.2174/0929867328666210311112240
View Abstract View on PubMed








Lipid-Lowering Therapies for Atherosclerosis: Statins, Fibrates, Ezetimibe and PCSK9 Monoclonal Antibodies


Adel Hajj Ali, Nour Younis, Rola Abdallah, Farah Shaer, Ali Dakroub, Mohammed Ayoub, Rabah Iratni, Hadi Mohamad Yassine, Kazem Zibara, Alexander Orekhov, Ahmed Fawzy El-Yazbi and Ali Eid *


DOI: 10.2174/0929867328666210222092628
View Abstract View on PubMed


Conventional and Non-Conventional Targets of Natural Products in the Management of Diabetes Mellitus and Associated Complications


Mohamad Fawzi Mahomoodally, Devina Lobine, Marie Carene Nancy Picot-Allain, Nabeelah Sadeer, Sharmeen Jugreet and Gokhan Zengin*


DOI: 10.2174/0929867327666201102120120
View Abstract View on PubMed


Na, K-ATPase as a Biological Target for Gold(III) Complexes: A Theoretical and Experimental Approach


Aleksandra M. Bondžić, Dragana D. Vasić Anićijević, Goran V. Janjić, Ivana Zeković, Tatjana Momić, Ana Vujačić Nikezić and Vesna M. Vasić*


DOI: 10.2174/0929867328999210101233801
View Abstract View on PubMed


Advances of Inorganic Materials in the Detection and Therapeutic Uses Against Coronaviruses


Sathish Veerasamy*, Manivannan Chandrakumar, Malathi Balasubramaniyan, Ramesh Kumar Arumugam and Thanasekaran Pounraj*


DOI: 10.2174/0929867328666210219142208
View Abstract View on PubMed








Engineered Polymer Nanoplatforms for Targeted Tumor Cells and Controlled Release Cargos to Enhance Cancer Treatment


Zhenjie Wang, Longguang Tang, Qingchun Mu, Siyao Che*, Yongbing Sun*, Lei Bai, Yan Luo, Yeguo Yang, Meng Yu and Zhiqiang Yu*


DOI: 10.2174/0929867328666210226143148
View Abstract View on PubMed


Bladder Cancer: Update on Risk Factors, Molecular and Ultrastructural Patterns


Liudmila M. Mikhaleva*, Valentina V. Pechnikova, Akhmed M. Pshikhachev, Konstantin A. Rogov, Magomed A. Gusniev, Olga I. Patsap, Olesya A. Vasyukova, Emma P. Akopyan, Ozal Beylerli, Siva G. Somasundaram, Cecil E. Kirkland and Gjumrakch Aliev*


DOI: 10.2174/0929867328666210309111731
View Abstract View on PubMed


MicroRNAs as Biomarkers in Hypertrophic Cardiomyopathy: Current State of the Art


Andreas Angelopoulos, Evangelos Oikonomou*, Georgia Vogiatzi, Alexios Antonopoulos, Sotirios Tsalamandris, Christos Georgakopoulos, Paraskevi Papanikolaou, George Lazaros, Georgios Charalambous, Gerasimos Siasos, Charalambos Vlachopoulos and Dimitris Tousoulis


DOI: 10.2174/0929867328666210405122703
View Abstract View on PubMed


Astrocytes and Inflammasome: A Possible Crosstalk in Neurological Diseases


Fahimeh Nourbakhsh, Morgayn I. Read, George E. Barreto and Amirhossein Sahebkar*


DOI: 10.2174/0929867328666210301105422
View Abstract View on PubMed






Novel Nitrogen Containing Steroid Derivatives for Prostate Cancer Treatment


Alexandra S. Latysheva, Vladimir A. Zolottsev, Vadim S. Pokrovsky*, Irina I. Khan and Alexander Yu. Misharin


DOI: 10.2174/0929867328666210208113919
View Abstract View on PubMed


Natural Products as Potential Agents Against SARS-CoV and SARSCoV- 2


Joanda Paolla Raimundo e Silva, Chonny Alexander Herrera Acevedo, Thalisson Amorim de Souza, Renata Priscila Barros de Menezes, Zoe L. Sessions, Lucas Silva Abreu, Samuel Paulo Cibulski, Luciana Scotti, Marcelo Sobral da Silva, Eugene N. Muratov, Marcus Tullius Scotti and Josean Fechine Tavares*


DOI: 10.2174/0929867328666210125113938
View Abstract View on PubMed


Recent Progress in Small Molecular Inhibitors of DNA Gyrase


Ruo-Jun Man, Xu-Ping Zhang, Yu-Shun Yang*, Ai-Qin Jiang* and Hai-Liang Zhu*


DOI: 10.2174/1871529X21666210202113128
View Abstract View on PubMed




Using natural Compounds to Target KRAS Mutated Non-Small Cell Lung Cancer


Mahruba Sultana Niloy, Md. Salman Shakil, Md. Meharab Hassan Alif and Rhonda J. Rosengren*


DOI: 10.2174/0929867328666210301105856
View Abstract View on PubMed



Nucleoside Inhibitors of Coronaviruses


Anastasia A. Zenchenko*, Mikhail S. Drenichev and Sergey N. Mikhailov


DOI: 10.2174/0929867328666210208181724
View Abstract View on PubMed




MicroRNAs in the Management of Heart Failure


Aimilios Kalampogias, Gerasimos Siasos, Evangelos Oikonomou*, Konstantinos Mourouzis, Evanthia Bletsa, Panagiota K. Stampouloglou, Efstratios Katsianos, Konstantinos Vlasis, Georgios Marinos, Georgios Charalambous, Manolis Vavouranakis and Dimitris Tousoulis


DOI: 10.2174/0929867328666210218181441
View Abstract View on PubMed


Novel Biomarkers for Lupus Nephritis in the “OMICS” Era


Raphael Dias, Ursula Gramiscelli Hasparyk, Monisi Lopes Peres, João Luiz Vieira Monteiro de Barros and Ana Cristina Simões e Silva*


DOI: 10.2174/0929867328666210212102438
View Abstract View on PubMed



Extracellular Vesicles in the Treatment of Parkinson’s Disease: A Review


Xiaoxiao Yang, Yifan Ma, Haotian Xie, Shiyan Dong, Gaofeng Rao, Zhaogang Yang*, Jingjing Zhang* and Qingqing Wu*


DOI: 10.2174/0929867328666210113170941
View Abstract View on PubMed


Viral Envelope Membrane: A Special Entry Pathway and a Promising Drug Target


Nastasja Palombi, Annalaura Brai, Martina Gerace, Salvatore Di Maria, Francesco Orofino and Federico Corelli*


DOI: 10.2174/0929867328666210218182203
View Abstract View on PubMed


Neurokinin-1 Receptor (NK-1R) Antagonists: Potential Targets in the Treatment of Glioblastoma Multiforme


Amir R. Afshari, Ali Motamed-Sanaye, Hamed Sabri, Arash Soltani, Sepideh Karkon-Shayan, Sarvin Radvar, Hossein Javid, Hamid Mollazadeh, Thozhukat Sathyapalan and Amirhossein Sahebkar*


DOI: 10.2174/0929867328666210113165805
View Abstract View on PubMed


An Overview of the α4β 1 Integrin and the Potential Therapeutic Role of its Antagonists


Elenilze F. B. Ferreira , Luciane B. Silva , Josiane V. Cruz, Pedro H. F. Araújo, Njogu M. Kimani, Franco H. A. Leite , Joaquín M. Campos * and Cleydson B. R. Santos


DOI: 10.2174/0929867328666210217153609
View Abstract View on PubMed


Lipid Metabolism and Relevant Disorders to Female Reproductive Health


María José Ferrer, Aimé Florencia Silva, Giselle Adriana Abruzzese, Mariela Edith Velázquez and Alicia Beatriz Motta*


DOI: 10.2174/0929867328666210106142912
View Abstract View on PubMed







The Role of Pharmacogenetics in Antithrombotic Therapy Management: New Achievements and Barriers Yet to Overcome


V. Conti, G. Corbi*, V. Manzo, C. Sellitto, F. Iannello, S. Esposito, E. De Bellis, T. Iannaccone and A. Filippelli


DOI: 10.2174/0929867328666201231124715
View Abstract View on PubMed




Machine Learning Approaches in Parkinson’s Disease


Annamaria Landolfi*, Carlo Ricciardi, Leandro Donisi, Giuseppe Cesarelli, Jacopo Troisi, Carmine Vitale, Paolo Barone and Marianna Amboni


DOI: 10.2174/0929867328999210111211420
View Abstract View on PubMed


Electrostatic Potential Energy in Protein-Drug Complexes


Gabriela Bitencourt-Ferreira and Walter Filgueira de Azevedo Junior*


DOI: 10.2174/0929867328666210201150842
View Abstract View on PubMed







Recent Advances in Glycosidase Probes Used in Escherichia Coli Detection


Xianhu Wei, Ying Feng, Minling Chen, Shuhong Zhang, Moutong Chen, Jumei Zhang, Youxiong Zhang, Qinghua Ye, Yu Ding, Liang Xue and Qingping Wu*


DOI: 10.2174/0929867328999201224111615
View Abstract View on PubMed


Artificial Intelligence as a Business Partner in Cardiovascular Precision Medicine: An Emerging Approach for Disease Detection and Treatment Optimization


Valeria Visco, Germano Junior Ferruzzi, Federico Nicastro, Nicola Virtuoso, Albino Carrizzo, Gennaro Galasso, Carmine Vecchione and Michele Ciccarelli*


DOI: 10.2174/0929867328666201218122633
View Abstract View on PubMed


Chitosan Nanoparticles Potentiate the in vitro and in vivo Effects of Curcumin and other Natural Compounds


Vanessa Falchetti Lopes, Camila Nascimento Giongo, Laís de Almeida Campos, Wolf-Rainer Abraham, Rubiana Mara Mainardes* and Najeh Maissar Khalil


DOI: 10.2174/0929867328666201124152945
View Abstract View on PubMed





The Therapeutic use of the Zonulin Inhibitor AT-1001 (Larazotide) for a Variety of Acute and Chronic Inflammatory Diseases


Jacopo Troisi*, Giorgia Venutolo, Concetta Terracciano, Matteo Delli Carri, Simone Di Micco, Annamaria Landolfi and Alessio Fasano


DOI: 10.2174/0929867328666210104110053
View Abstract View on PubMed



Design and Synthesis of Quinolizidine Derivatives as Influenza Virus and HIV-1 Inhibitors


Zhao Dang, Lei Zhu, Lan Xie, Kuo-Hsiung Lee, Faisal Malik, Zhijun Li, Li Huang* and Chin-Ho Chen*


DOI: 10.2174/0929867328666201229121802
View Abstract



Alport Syndrome: A comprehensive review on genetics, pathophysiology, histology, clinical, and therapeutic perspectives


Ana Luisa Pedrosa, Letícia Bitencourt, Rafaela Moreira Paranhos, Cristiana Afonso Leitão, Guilherme Costa Ferreira and A. C. Simões e Silva*


DOI: 10.2174/0929867328666210108113500
View Abstract View on PubMed


Research Domain Criteria (RDoC): A Perspective to Probe the Biological Background Behind Treatment Efficacy in Depression


Marco Calabrò, Chiara Fabbri, Siegfried Kasper, Joseph Zohar, Daniel Souery, Stuart Montgomery, Diego Albani, Gianluigi Forloni, Panagiotis Ferentinos, Dan Rujescu, Julien Mendlewicz, Roberto Colombo, Diana De Ronchi, Alessandro Serretti* and Concetta Crisafulli


DOI: 10.2174/0929867328666210104104938
View Abstract View on PubMed



Competing Endogenous RNAs (CeRNAs): Novel Network in Neurological Disorders


Sadra Samavarchi Tehrani, Reyhane Ebrahimi, Atiyeh Al-e-Ahmad, Ghodratollah Panahi, Reza Meshkani, Simin Younesi, Payam Saadat and Hadi Parsian*


DOI: 10.2174/0929867328666201217141837
View Abstract View on PubMed


The Role of Interleukin-6 in the Pathogenesis, Prognosis and Treatment of Severe COVID-19


Ilias Giannakodimos, Georgia-Vasiliki Gkountana, Dimosthenis Lykouras, Kiriakos Karkoulias* and Sotiris Tsakas


DOI: 10.2174/0929867328666201209100259
View Abstract View on PubMed





The Hydroxamic Acids as a Potential Anticancer and Neuroprotective Agents


Margarita E. Neganova, Sergey G. Klochkov, Yulia R. Aleksandrova and Gjumrakch Aliev*


DOI: 10.2174/0929867328666201218123154
View Abstract






The Potential Clinical Properties of Magnesium


Guido Crisponi*, Valeria Marina Nurchi, Rosita Cappai, Maria Antonietta Zoroddu, Clara Gerosa, Monica Piras, Gavino Faa and Daniela Fanni


DOI: 10.2174/0929867327999201116195343
View Abstract View on PubMed





Anti-tumor Effects of Curcuminoids in Glioblastoma Multiforme: An Updated Literature Review


Amir R. Afshari, Mohammad Jalili-Nik, Farzaneh Abbasinezhad-moud, Hossein Javid, Mohammad Karimi, Hamid Mollazadeh, Tannaz Jamialahmadi, Thozhukat Sathyapalan and Amirhossein Sahebkar*


DOI: 10.2174/0929867327666201111145212
View Abstract View on PubMed


Targeted Delivery of Natural Bioactives and Lipid-nanocargos against Signaling Pathways Involved in Skin Cancer


Mohammad Kashif Iqubal, Aiswarya Chaudhuri, Ashif Iqubal, Sadaf Saleem, Madan Mohan Gupta, Alka Ahuja, Javed Ali and Sanjula Baboota*


DOI: 10.2174/0929867327666201104151752
View Abstract View on PubMed




Natural Anti-inflammatory Compounds as Drug Candidates in Alzheimer’s Disease


Reyaz Hassan Mir, Abdul Jalil Shah, Roohi Mohi-ud-din, Faheem Hyder Pottoo, Mohd. Akbar Dar, Sanjay M Jachak* and Mubashir Hussain Masoodi


DOI: 10.2174/0929867327666200730213215
View Abstract View on PubMed




mTor Targeting by Different Flavonoids for Cancer Prevention


Badar ul Islam, Mohd Shahnawaz Khan, Fohad Mabood Husain, Md Tabish Rehman, Torki A. Alzughaibi, Adel M. Abuzenadah, Maryam Urooj, Mohammad Amjad Kamal and Shams Tabrez*


DOI: 10.2174/0929867327666201109122025
View Abstract View on PubMed









Exosome-Mediated Drug Delivery for Cell-Free Therapy of Osteoarthritis


Li Duan*, Xiao Xu, Limei Xu, Hongfei Chen, Xingfu Li, Murad Alahdal, Yin Xiao, Yujie Liang and Jiang Xia


DOI: 10.2174/0929867327666201118161232
View Abstract View on PubMed




Potential Repurposing of Drugs with Anti-SARS-CoV-2 Activity in Preclinical Trials: A Systematic Review


Yasmim Mendes Rocha, Gabriel Acácio de Moura, Juliana Ramos de Oliveira, Larissa Deadame de Figueiredo Nicolete and Roberto Nicolete*


DOI: 10.2174/0929867327666201005113204
View Abstract View on PubMed




Renin-angiotensin System (RAS) and Immune System Profile in Specific Subgroups with COVID-19


Ludimila de Barcelos Ubaldo Martins, Luiz Gustavo Pessoa Pires Jabour, Cristina Cerqueira Vieira, Lucas Crepaldi Carvalho Nery, Raphael Figuiredo Dias and Ana Cristina Simões e Silva*


DOI: 10.2174/0929867327666200903113117
View Abstract View on PubMed



Chemo-drug Controlled-release Strategies of Nanocarrier in the Development of Cancer Therapeutics


Yunyi Liu, Hailong Ou, Xiaming Pei, Bin Jiang, Yihan Ma, Naiyu Liu, Chaoqi Wen, Chen Peng and Xiaoxiao Hu*


DOI: 10.2174/0929867327666200605153919
View Abstract View on PubMed







Editor-in-Chief

Atta-ur-Rahman, FRS
(32052 citations)
Honorary Life Fellow
Kings College
University of Cambridge
Cambridge
(UK)
Biography
View Full Editorial Board

Nobel Laureates on Editorial Board

Prof. John Gurdon
(UK)

Prof. Jean-Marie Lehn
(France)

Prof. Ferid Murad
(USA)

COPE Compliant

Cope Logo

Journal History

Current Medicinal Chemistry was introduced in 1994 with the assistance of Dr. Atta-ur-Rahman, who is the current Editor-in-Chief serving since 1994.

Advertisement

webinar-July-21

Related Journals

Related eBooks

eBooks Catalog