Contents

Current Gene Therapy, Volume 9 - Number 5

Editorial [Hot topic: Gene Therapy Continues to Make Progress: Clinical and Regulatory Perspectives (Guest Editors: Maria G. Castro and Pedro R. Lowenstein)]

, 9(5): 327 - 328

Maria G. Castro and Pedro R. Lowenstein


DOI: 10.2174/156652309789753374




Progress Towards Liver and Lung-Directed Gene Therapy with Helper- Dependent Adenoviral Vectors

, 9(5): 329 - 340

Nicola Brunetti-Pierri and Philip Ng


DOI: 10.2174/156652309789753310




“Buy One Get One Free”: Armed Viruses for the Treatment of Cancer Cells and their Microenvironment

, 9(5): 341 - 355

Balveen Kaur, Timothy P. Cripe and E. Antonio Chiocca


DOI: 10.2174/156652309789753329




Adenovirus Mediated Herpes Simplex Virus-Thymidine Kinase/Ganciclovir Gene Therapy for Resectable Malignant Glioma

, 9(5): 356 - 367

Ann-Marie Maatta, Haritha Samaranayake, Jere Pikkarainen, Thomas Wirth and Seppo Yla-Herttuala


DOI: 10.2174/156652309789753365




Uncertainty in the Translation of Preclinical Experiments to Clinical Trials. Why do Most Phase III Clinical Trials Fail?

, 9(5): 368 - 374

Pedro R. Lowenstein and Maria G. Castro


DOI: 10.2174/156652309789753392




Gene Therapy for Neurological Disorders: Challenges and Future Prospects for the Use of Growth Factors for the Treatment of Parkinsons Disease

, 9(5): 375 - 388

Fredric p. Manfredsson, Michael S. Okun and Ronald J. Mandel


DOI: 10.2174/156652309789753400




Stem Cells as Delivery Vehicles for Oncolytic Adenoviral Virotherapy

, 9(5): 389 - 395

Justin Kranzler, Matthew A. Tyler, Adam M. Sonabend, Ilya V. Ulasov and Maciej S. Lesniak


DOI: 10.2174/156652309789753347




Immunotherapy of Human Cancers Using Gene Modified T Lymphocytes

, 9(5): 396 - 408

Juan F. Vera, Malcolm K. Brenner and Gianpietro Dotti


DOI: 10.2174/156652309789753338




Gene Therapy for Brain Cancer: Combination Therapies Provide Enhanced Efficacy and Safety

, 9(5): 409 - 421

Marianela Candolfi, Kurt M. Kroeger, A. K.M.G. Muhammad, Kader Yagiz, Catherine Farrokhi, Robert N. Pechnick, Pedro R. Lowenstein and Maria G. Castro


DOI: 10.2174/156652309789753301




Oncolytic Adenovirus: Preclinical and Clinical Studies in Patients with Human Malignant Gliomas

, 9(5): 422 - 427

Hong Jiang, Candelaria Gomez-Manzano, Frederick F. Lang, Ramon Alemany and Juan Fueyo


DOI: 10.2174/156652309789753356




AAV as a Gene Transfer Vector for the Treatment of Neurological Disorders: Novel Treatment Thoughts for ALS

, 9(5): 428 - 433

Mark E. Hester, Kevin D. Foust, Rita W. Kaspar and Brian K. Kaspar


DOI: 10.2174/156652309789753383




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