Current Enzyme Inhibition
Volume 16, 3 Issues, 2020
ISSN: 1875-6662 (Online)
ISSN: 1573-4080 (Print)
This journal supports open access
ISSN: 1875-6662 (Online)
ISSN: 1573-4080 (Print)
This journal supports open access
In the current pandemic scenario, publication process of all articles related to Coronavirus will be expedited, for timely publication of much needed research
Editorial Board
Editor-in-Chief
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Claudiu T. Supuran (83932 citations) University of Florence Florence Italy Biography Biography of Claudiu T. Supuran
CLAUDIU T. SUPURAN is professor of medicinal chemistry at the Neurofarba Department, Section of Pharmaceutical and Nutriceutical Sciences, University of Florence, Italy. He has published more than 1250 papers, his Hirsch factor is h = 110; the number of citations since 1995 > 49800. His main research interest is on enzyme inhibitors, and especially carbonic anhydrase inhibitors, of which he discovered several new classes in the last years. One of the sulfonamides discovered in his group entered Phase I clinical trials in 2014 for the treatment of advanced, metastatic solid tumors. He is Editor-in-Chief of Expert Opinion on Therapeutic Patents, Journal of Enzyme Inhibition and Medicinal Chemistry, Current Enzyme Inhibition, etc. For the last 25 years the main interest of his research was focused on metallo-enzymes and their modulators of activity. In 2013 he was rated as the most cited scientists in Pharmacology & Toxicology by LabTimes (LabTimes 2013, 5, 38).
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Co-Editor
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D. Hadjipavlou-Litina Aristotle University of Thessaloniki Thessaloniki Greece Biography Biography of D. Hadjipavlou-Litina
Professor Dimitra Hadjipavlou-Litina received her undergraduate training in Pharmacy at Aristotle University of Thessaloniki, Greece (1975-1979) and her PhD in Pharmacy at the same University. She conducted postdoctoral studies at California (supervisor Professor Corwin Hansch). Currently she is a full professor and a head at the School of Pharmacy.
Her research interests involve synthesis and biological studies and the use of Computational Chemistry in Drug Design and resulted in the publication of over 220 peer-reviewed articles over 5000 citations and h factor = 38. Currently is the Editor of this journal (Current Enzyme Inbibition, CEI), published by Bentham Science Publishers.
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Associate Editors
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A.M. Alafeefy Prince Sattam Bin Abdulaziz University Al-Kharj Saudia Arabia Biography Biography of A.M. Alafeefy
Dr. Ahmed M Alafeefy got his PhD, Pharmaceutical Chemistry, in 2005 from Egypt and left for Saudi
Arabia. His current research interest covers the development of potential drugs to combat
cancer and viral diseases. He has been consistently working to locate biochemical rationale
which enables the preparation of antitumor drugs focusing on qualitative differences between
normal and cancerous cells. The complementary development of semisynthetic biologically
active small molecules as antiviral, anticancer agents is his future aim. Currently, he is an Assoc.
Prof. of Pharmaceutical Chemistry Kulliyyah of Science, IIUM, Malaysia. He has published more
than 40 papers in reputed journals.
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M.A. Ilies Temple University Philadelphia, PA USA Biography Biography of M.A. Ilies
Dr. Marc A. Ilies was born and educated in Romania, and received his PhD in 2001 with
Professor Alexandru T. Balaban from C. D. Nenitzescu’s Department of Organic Chemistry of
Polytechnic University of Bucharest. After post-doctoral studies from Texas A&M University and
University of Pennsylvania, he joined the Department of Pharmaceutical Sciences, School of
Pharmacy, Temple University, where he is currently an Associate Professor and an affiliated
member of Moulder Center for Drug Discovery Research. His research interests fit within the
broadly-defined medicinal chemistry/chemical biology of membrane interfaces, being focused
on the development of chemical solutions for the efficient and selective delivery of drugs and
nucleic acids for therapeutic purposes.
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Regional Editor
Europe
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G. Costa Magna Græcia University Catanzaro Italy Biography Biography of G. Costa
Dr. Giosuè Costa obtained a degree in “Pharmacy” with full marks in 2008 from the University
"Magna Græcia" of Catanzaro. Then he followed the three- year doctorate in Pharmaceutical
Sciences, continuing his research activity in the field of interactions between bio-molecules by
innovative molecular modeling tools. In 2012, at the same University, he obtained the Ph.D. in
Pharmaceutical Sciences, discussing a thesis entitled "Computational studies applied to HIV-1
macromolecular targets and implications in rational drug design of new selective antiviral
agents". Dr. Giosuè Costa collaborates with several foreign departments. Currently, he is a
Postdoctoral Researcher at the Department of Health Science of “Magna Graecia” University of
Catanzaro (Italy) with H-index= 18 (Scopus) and no. of citations = 810 (Scopus). His scientific
interests concern the application of new computational algorithms, and in particular Virtual
Screening techniques, for the study of intermolecular drug-receptor interactions and the design
of potential antitumoral, antiviral, analgesic and antidepressant drugs. In the nutraceutical
field, his interest is mainly in the identification of potential therapeutic activities in natural
products contained in foods. Furthermore, in the field of drug discovery, he studies the
"repositioning" for other therapeutic indications (or rationalizing some side effects) of drugs
previously approved by the FDA.
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Section Editors
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Section: Emerging enzyme inhibitors from natural compounds
S. CarradoriUniversity of Chieti-Pescara Pescara Italy Biography Biography of S. Carradori
Dr. Simone Carradori obtained his Ph.D. in Pharmaceutical Sciences from Sapienza University of
Rome (Italy). Currently, he is an assistant professor of Medicinal Chemistry at the Department
of Pharmacy of “G. D’Annunzio” University of Chieti-Pescara (Italy). His scientific activity is
mainly focused on the characterization and synthesis of novel synthetic and natural derivatives
with potential biological activity and has published 4 papers in international peer-reviewed
journals and one patent.
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Frontiers Section Editor
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Section: Pharmaceutical Chemistry
F. CartaUniversity of Florence Florence Italy Biography Biography of F. Carta
Dr. Fabrizio Carta received his degree in 2002 in Pharmaceutical Chemistry and Technology
from the University of Sassari (IT). In 2008 he received his Ph.D. in Chemistry at the School of
Chemistry of the Bristol University (UK), he was appointed as a postdoctoral fellow at MIT (USA)
and finally joined Prof. Scozzafava’s and Supuran’s groups at the University of Florence (IT).
Among others, he is an Editorial Board Member of the Journal of Enzyme Inhibition and
Medicinal Chemistry (JEIMC) and Journal of the Turkish Chemical Society, Section A: Chemistry
(JOTCSA). Co-author of 100 publications on peer-reviewed international journals, 3 book
chapters. 4 patents.
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Section: Drug and Bioactive Substances
G. PoliUniversity of Pisa Pisa Italy Biography Biography of G. Poli
Dr. Giulio Poli obtained his MD in Medicinal Chemistry and his PhD in Science of Drug and
Bioactive Substances from the Department of Pharmacy, University of Pisa (Italy). Currently, he
is an untenured assistant professor in Medicinal Chemistry at the Department of Pharmacy,
University of Pisa (Italy). His research activity at the Molecular Modeling and Virtual Screening
Laboratory mainly focuses on the development of efficient virtual screening protocols and
innovative computational procedures for the identification of hit/lead compounds of various
protein targets, as well as on lead and hit-to-lead optimization studies.
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Editorial Board Members
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Z.A. ALOthman King Saud University Riyadh Saudi Arabia Biography Biography of Z.A. ALOthman
Zeid A. ALOthman, Professor of Chemistry, at Chemistry Department, College of Science, King Saud University, Riyadh, Saudi Arabia. He obtained his Ph.D. in chemistry at Oklahoma State University in 2006.
He is working on a variety of topics ranging from the high surface area materials, Water treatment and production, Ion exchanger, separation and Environmental studies.
He is the group leader of Advanced Materials and Chromatography Group and the supervisor of the Advanced Materials Research Chair.
He supervised seven PhD students and more than 12 master students.
He is an author and co-author of more than 350 scientific publications, three books and six patents.
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A. Akdemir Bezmialem Vakif University Istanbul Turkey Biography Biography of A. Akdemir
Dr. Akdemir obtained his PhD and MSc from the Department of Pharmaceutical Sciences (VU University Amsterdam, The Netherlands). His research interests are mainly molecular modelling and molecular pharmacology studies of various drug targets (including carbonic anhydrases and nicotinic acetylcholine receptors). He is currently associate professor of pharmacology and vice-dean at the Faculty of Pharmacy (Bezmialem Vakif University, Istanbul, Turkey).
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D. Barreca Università di Messina Messina Italy Biography Biography of D. Barreca
Davide Barreca is an Assistant Professor of biochemistry at the University of Messina. He is
specialized in enzyme modulation by natural compounds, inhibition of protein aggregation and
analysis of enzymatic pattern. Most of his research projects concentrate on separation and
identification of unknown flavonoids, structural-activity elucidation, and biochemical analysis of
their health promoting or cytotoxicity properties on cells culture, exploring their suitable
employment in pharmaceutical as well as nutraceutical food supplements. He is author of 86 papers
in peer-reviewed journals, 30 chapters in books, and 70 conference proceedings, reviewer of over
40 international scientific journals, and evaluator of research.
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S. Cai University of Massachusetts Dartmouth Dartmouth, MA United States Biography Biography of S. Cai
Dr. Shuowei Cai is currently a Professor at the Department of Chemistry and Biochemistry, University of Massachusetts Dartmouth. He did M.S. in Analytical Chemistry from Nankai Univerity, Tianjin, P. R. China in 1993 and M.S. in Chemistry from University of Massachusetts Dartmouth, Dartmouth, MA in 1998. Later, he obtained a PhD in Biological Chemistry from University of Massachusetts Amherst, Amherst, MA in 2001.
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C. Capasso Piazzale Aldo Moro Rome Italy Biography Biography of C. Capasso
Dr. Clemente Capasso is a researcher at the National Research Council. His research interest
from 1992 to date has been the study of the structure/function relationship of both native
and recombinant proteins from terrestrial, marine organisms and pathogenic
microorganisms. This allowed him to acquire extensive knowledge of most protein
purification procedures as well as kinetic, chemical–physical and structural characterization
of enzymes. He has written 13 book chapters and published over 100 papers. He acquired
an intense training in Italian and international laboratories. He is the Associate Editor of
Journal of Enzyme Inhibition and Medicinal Chemistry, and is in the Editorial Board of the
journal Expert Opinion on Therapeutic Patents.
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P.A. Colinas Investigador Independiente (CONICET), LADECOR La Plata Argentina Biography Biography of P.A. Colinas
Dr Colinas received his Ph.D. in chemistry from the Universidad Nacional de La Plata (Argentina) en 1997. He then worked as postdoctoral fellow in the Institut für Organische Chemie, Universität Stuttgart (Germany). In 2006 he became Adjunct Professor of organic chemistry in the Universidad Nacional de La Plata. Since 2005 he is member of the Scientific Research Career of CONICET (Argentina). He has published more than 40 scientific publications. His research interests include carbohydrate chemistry, design of enzyme inhibitors and medicinal chemistry.
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M. Ferraroni University of Florence Sesto Fiorentino Italy Biography Biography of M. Ferraroni
Dr. Marta Ferraroni obtained her degree and her PhD in Chemistry from the University of
Florence, Italy. Currently, she is a researcher at the Department of Chemistry, University of
Florence. The activity of Dr. Ferraroni is primarily focused in the field of Bioinorganic and
Medicinal Chemistry, and its aim is the comprehension of the structure-activity relationships of
metalloenzymes involved in relevant processes. Dr. Ferraroni is a co-author of 55 scientific
articles and of 3 chapter of books edited by international publishing companies.
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I. Glucin Ataturk University Erzurum Turkey Biography Biography of I. Glucin
Prof. Dr. İlhami GÜLÇİN obtained a doctorate (Ph.D.) in Chemistry from the Ataturk University of Erzurum, Turkey. He is the member of Turkish Academy of Sciences (TÜBA). He has experience in the research of enzyme purification, enzyme inhibition, antioxidant activity, and biological activities. He has also published more than 200 scientific publications. His manuscripts have more than 9000 citations.
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A. Karioti Aristotle University Thessaloniki Greece Biography Biography of A. Karioti
A. Karioti is Assistant Professor at the Dept. of Pharmaceutical Sciences, Aristotle University of Thessaloniki, Greece, has a Ph.D. in Pharmacognosy of Bioactive Natural Products from the University of Athens, Greece. She served for eight years as Teaching and Research Assistant in Univ. of Florence, Italy (2007-2014). In general the main research lines are Isolation and structural identification of a wide range of natural constituents (both phenols and terpenoids), Pharmacological evalution of extracts and purified constituents and Development of analytical methods for the quality control of herbal medicinal plants and preparations and products thereof. She is author of 77 publications, h-index 19 (google scholar).
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M. Mori Italian Institute of Technology Roma Italy Biography Biography of M. Mori
Dr. Mattia Mori obtained his degree in Medicinal Chemistry and his PhD in Structural Biology
from the University of Florence, Italy. Currently, he is a researcher at the Center for Life Nano
Science at Sapienza of the Istituto Italiano di Tecnologia (IIT) in Roma, Italy. The research
activity of Dr. Mori focuses on medicinal chemistry and drug discovery, with a particular
dedication to the use of computer simulations to discover and develop bioactive small
molecules, or to study the conformational space of target proteins. Dr. Mori is a co-author of
more than 45 papers and 1 patent.
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D. Poirier CHUQ and Universite Laval Quebec City, QC Canada Biography Biography of D. Poirier
Dr. Donald Poirier received his basic training in organic chemistry (PhD at Université Laval, 1980-1985) and subsequently specialized in medicinal chemistry and endocrinology (Post-doctorat at CHUL - Research Center, 1986-1990). Professor at Université Laval since 1991, he is especially interested in the development of inhibitors of steroidogenic enzymes (steroid sulfatase and 17β-HSDs types 1, 2, 3, 7 and 12) and antitumor agents for the treatment of different diseases (breast, prostate and leukemia cancers, endometriosis, osteoporosis and Alzheimer). He is also interested to additional aspects of organic chemistry (synthesis, solid-phase synthesis, new methodologies, NMR analysis, etc.) and medicinal chemistry (SAR and QSAR analysis, molecular modeling, biological assays, etc.). He has published 204 scientific publications and 9 patent applications.
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S. Singh Bareilly College Bareilly India Biography Biography of S. Singh
Dr. Shalini Singh is presently working as an Assistant Professor in the Department of
Chemistry, Bareilly College, Bareilly (U.P.) India. She holds a Ph.D. from A.P.S. University
Rewa, (M.P). She has got awards and rewards of an unending sequence like Recipient of
D.S.T. Women Scientist Scheme Award (WOS-A), U.G.C. Research Awardee 2011, Recipient
of Indian Chemical Society Award-2012 Dr. Singh has contributed 42 research papers of
repute in high impact factor Journals. Dr. Singh is a fellow member of Indian Chemical
Society Kolkatta, India. Dr Singh is also a member of many prestigious Editorials boards of national and international reputed journals like Journal of Enzyme Inhibition and Medicinal
Chemistry.
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M.A. Sogorb University Miguel Hernández Elche Spain Biography Biography of M.A. Sogorb
Dr. Sogorb is a Faculty Professor of Toxicology at Miguel Hernández University (Spain). He
started my research career in biochemical Toxicology with the characterization of enzymes
involved in the detoxication of organophosphorus insecticides. At the same time he was
involved in the characterization of Neuropathy Target Esterase (an esterase target of
organophosphorus insecticides) in in vitro cellular models. Dr. Sogorb performed a
postdoctoral stay (2 years) at the Texas A&M University where he was involved the
generation and characterization of mutant bacterial phosphotriesterases by site-directed
mutagenesis for enhancing and modulating their catalytic efficacy. Nowadays, his records
include 59 papers in peer-review journals and 8 book chapters.
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S. Thibaudeau University of Poitiers Poitiers France Biography Biography of S. Thibaudeau
Sébastien Thibaudeau is professor of organic chemistry at the University of Poitiers. He completed his MD and PhD in Poitiers (France) and a fellowship at chemistry department in Oxford University (UK). He is head of the superacid group in the organic synthesis team of the Institute of Chemistry of Poitiers (IC2MP). His current research is mainly focused on the use of superacid activation in organic and bio-organic chemistry.
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D. Vullo University of Florence Florence Italy Biography Biography of D. Vullo
Dr. Daniela Vullo obtained her Ph.D. in Chemistry at the University of Florence, Italy. Currently, she has a post-doc position at the same university, Department of Chemistry “Ugo Shiff” under the supervision of Prof. Andrea Scozzafava and Prof. Claudiu T. Supuran. The scientific research is focused on enzyme activity characterization, mainly carbonic anhydrase inhibitors and activators and resulted in the publication of over 280 papers with Hirsch factor h=51 and 9112 citations.
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P. Zhan Shandong University Jinan China Biography Biography of P. Zhan
Peng Zhan obtained his B.S. degree from Shandong University, China, in 2005. Then he earned his M.S. degree and Ph.D. in medicinal chemistry from Shandong University in 2008 and 2010, respectively. He subsequently joined the research group of Professor Xinyong Liu as a Lecturer (2010–2012). From 2012 to 2014, he worked as a Postdoctoral Fellow funded by JSPS (Japan Society for the Promotion of Science) in the Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Japan. He is currently an associate professor in the Institute of Medicinal Chemistry, Shandong University. His research interests involve the discovery of novel antiviral, anticancer, and neurodegenerative diseases-related agents based on rational drug design and combinatorial chemistry approaches.
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Associate Editorial Board Member
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A. Nocentini University of Florence Florence Italy Biography Biography of A. Nocentini
Alessio Nocentini, PhD obtained his MSc in Medicinal Chemistry and Technologies in 2014 and the PhD in medicinal chemistry at the University of Florence (Italy), where he now works as a post-doc researcher. He was awarded with the best PhD thesis Prize 2018 by the Medicinal Chemistry Division of the Italian Chemical Society. His research activity is mainly focused on the in silico design and synthesis of Carbonic Anhydrases modulators and their kinetic and biological characterization. He is author of over 40 publications in peer-reviewed scientific journals with a high impact factor and a considerable number of contributions in conference proceedings (Scopus H-index: 13; number of citations: 364).
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H.N. Thatoi North Orissa University Odisha India Biography Biography of H.N. Thatoi
Dr. H.N. Thatoi, is a Professor, Department of Biotechnology, North Orissa University, Odisha,
India and is also presently working as Director of Centre for Similipal Studies North Orissa
University. He obtained his M. Sc, M. Phil. and Ph. D. degree from Utkal University, Odisha,
and has more than 15 years of teaching and 25 years of research experience. He has contributed
immensely to the field of Microbiology and Biotechnology throughout his research and teaching
career and his research activities are mainly focused on exploration microbial diversity,
bioremediation, biofuel production, mangrove biology, bioactivity studies in medicinal plants
and mushrooms, ethno-pharmacology and biocomputational studies such as in silico drug design,
molecular docking, modeling and protein dynamism etc. His publication record is impressive
with more than 200 research papers published in various national and international journals and
30 book chapters. Prof. Thatoi has also authored two text books and 15 reference books
published by reputed national and international publishers.
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Executive Guest Editor(s)
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M. Ayyash United Arab Emirates University (UAEU) Al Ain United Arab Emirates Biography Biography of M. Ayyash
Dr. Mutamed Ayyash is an Associate Professor of Food Science (Food Microbiology) at the Department of Food, Nutrition, and Health at United Arab Emirates University (UAEU), UAE. His research interests focus on probiotics and its applications in fermented food products, especially camel milk and its products (yogurt, cheese, whey). Dr. Ayyash has published several articles that investigated the health benefits of fermented camel milk together with national and international collaborators. These research activities focus on finding novel methods to overcome the challenges of making fermented products from camel milk. Functional foods and exopolysaccharides are among the research interests of Dr. Ayyash.
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Editor-in-Chief
Claudiu T. Supuran
(83932 citations)
University of Florence
Florence
Italy
Biography
(83932 citations)
University of Florence
Florence
Italy
Biography
Biography of Claudiu T. Supuran
CLAUDIU T. SUPURAN is professor of medicinal chemistry at the Neurofarba Department, Section of Pharmaceutical and Nutriceutical Sciences, University of Florence, Italy. He has published more than 1250 papers, his Hirsch factor is h = 110; the number of citations since 1995 > 49800. His main research interest is on enzyme inhibitors, and especially carbonic anhydrase inhibitors, of which he discovered several new classes in the last years. One of the sulfonamides discovered in his group entered Phase I clinical trials in 2014 for the treatment of advanced, metastatic solid tumors. He is Editor-in-Chief of Expert Opinion on Therapeutic Patents, Journal of Enzyme Inhibition and Medicinal Chemistry, Current Enzyme Inhibition, etc. For the last 25 years the main interest of his research was focused on metallo-enzymes and their modulators of activity. In 2013 he was rated as the most cited scientists in Pharmacology & Toxicology by LabTimes (LabTimes 2013, 5, 38).
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Journal History
Current Enzyme Inhibition Journal was launched in 2005. Dr. Claudiu T. Supuran serves as the Editor-in-Chief of the journal.
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