Contents

Current Drug Targets, Volume 9 - Number 9

Editorial [Hot topic: Control and Regulation of Permeability of MDR Bacterial Pathogens to Antibiotics Presented by COST Action BM0701 (Guest Editors: L. Amaral and J.M. Pages)]

, 9(9): 718

Leonard Amaral and Jean Marie Pages


DOI: 10.2174/138945008785747815




Structure and Mechanism of Drug Efflux Machinery in Gram Negative Bacteria

, 9(9): 719 - 728

Zbigniew Pietras, Vassiliy N. Bavro, Nicholas Furnham, Marialuisa Pellegrini-Calace, E. James Milner-White and Ben F. Luisi


DOI: 10.2174/138945008785747743




The AcrB Efflux Pump: Conformational Cycling and Peristalsis Lead to Multidrug Resistance

, 9(9): 729 - 749

Markus A. Seeger, Kay Diederichs, Thomas Eicher, Lorenz Brandstatter, Andre Schiefner, Francois Verrey and Klaas M. Pos


DOI: 10.2174/138945008785747789




Membrane Permeability and Regulation of Drug “Influx and Efflux” in Enterobacterial Pathogens

, 9(9): 750 - 759

Anne Davin-Regli, Jean-Michel Bolla, Chloe E. James, Jean-Philippe Lavigne, Jacqueline Chevalier, Eric Garnotel, Alexander Molitor and Jean-Marie Pages


DOI: 10.2174/138945008785747824




New Methods for the Identification of Efflux Mediated MDR Bacteria, Genetic Assessment of Regulators and Efflux Pump Constituents, Characterization of Efflux Systems and Screening for Inhibitors of Efflux Pumps

, 9(9): 760 - 778

M. Viveiros, M. Martins, I. Couto, L. Rodrigues, G. Spengler, A. Martins, J. E. Kristiansen, J. Molnar and L. Amaral


DOI: 10.2174/138945008785747734




Physical Insights into Permeation of and Resistance to Antibiotics in Bacteria

, 9(9): 779 - 788

Matteo Ceccarelli and Paolo Ruggerone


DOI: 10.2174/138945008785747770




Biophysical Characterization of In- and Efflux in Gram-Negative Bacteria

, 9(9): 789 - 796

Helge Weingart, Mircea Petrescu and Mathias Winterhalter


DOI: 10.2174/138945008785747752




Clinical Impact of the Over-Expression of Efflux Pump in Nonfermentative Gram-Negative Bacilli, Development of Efflux Pump Inhibitors

, 9(9): 797 - 807

Jordi Vila and Jose Luis Martinez


DOI: 10.2174/138945008785747806




Antimicrobial Resistance in Foodborne Pathogens - A Cause for Concern?

, 9(9): 808 - 815

Ciara Walsh and Seamus Fanning


DOI: 10.2174/138945008785747761




Promising Therapy of XDR-TB/MDR-TB with Thioridazine an Inhibitor of Bacterial Efflux Pumps

, 9(9): 816 - 819

L. Amaral, M. Martins, M. Viveiros, J. Molnar and J. E. Kristiansen


DOI: 10.2174/138945008785747798




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