Current Drug Targets, Volume 8 - Number 3

Editorial [ Hot Topic: Targets for Development of Drugs Against Orphan Diseases (Guest Editor: Walter Filgueira de Azevedo Jr.) ]

, 8(3): 387

Walter Filgueira de Azevedo

DOI: 10.2174/138945007780058960

Protein Kinases as Targets for Antiparasitic Chemotherapy Drugs

, 8(3): 389 - 398

Fernanda Canduri, Patricia Cardoso Perez, Rafael A. Caceres and Walter F. de Azevedo

DOI: 10.2174/138945007780058979

Enoyl Reductases as Targets for the Development of Anti-Tubercular and Anti-Malarial Agents

, 8(3): 399 - 411

J. S. Oliveira, I. B. Vasconcelos, I. S. Moreira, D. S. Santos and L. A. Basso

DOI: 10.2174/138945007780058942

Purine Nucleoside Phosphorylase: A Potential Target for the Development of Drugs to Treat T-Cell- and Apicomplexan Parasite-Mediated Diseases

, 8(3): 413 - 422

R. G. Silva, J. E. S. Nunes, F. Canduri, J. C. Borges, L. M. Gava, F. B. Moreno, L. A. Basso and D. S. Santos

DOI: 10.2174/138945007780058997

Mycobacterial Shikimate Pathway Enzymes as Targets for Drug Design

, 8(3): 423 - 435

R. G. Ducati, L. A. Basso and D. S. Santos

DOI: 10.2174/138945007780059004

Chorismate Synthase: An Attractive Target For Drug Development Against Orphan Diseases

, 8(3): 437 - 444

Marcio V. B. Dias, Fernanda Ely, Mario S. Palma, Walter F. de Azevedo, Luiz A. Basso and Diogenes S. Santos

DOI: 10.2174/138945007780058924

The Inhibition of 5-enolpyruvylshikimate-3-phosphate Synthase as a Model for Development of Novel Antimicrobials

, 8(3): 445 - 457

Mauricio Ribeiro Marques, Jose Henrique Pereira, Jaim S. Oliveira, Luiz Augusto Basso, Walter Filgueira de Azevedo, Diogenes Santiago Santos and Mario Sergio Palma

DOI: 10.2174/138945007780058951

Shikimate Kinase: A Potential Target for Development of Novel Antitubercular Agents

, 8(3): 459 - 468

Jose H. Pereira, Igor B. Vasconcelos, Jaim S. Oliveira, Rafael A. Caceres, Walter F. de Azevedo, Luis A. Basso and Diogenes S. Santos

DOI: 10.2174/138945007780059013

Potentiality of Small Interfering RNAs (siRNA) as Recent Therapeutic Targets for Gene-Silencing

, 8(3): 469 - 482

Chiranjib Chakraborty

DOI: 10.2174/138945007780058988

Identifying and Attaining LDL-C Goals: Mission Accomplished? Next Target: New Therapeutic Options to Raise HDL-C Levels

, 8(3): 483 - 488

Vasilios G. Athyros, Dimitri P. Mikhailidis, Anna I. Kakafika, Asterios Karagiannis, Apostolos Hatzitolios, Konstantinos Tziomalos, Emmanuel S. Ganotakis, Evangelos N. Liberopoulos and Moses Elisaf

DOI: 10.2174/138945007780058933


, 8(3): 489

DOI: 10.2174/138945007780058915

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