Contents

Current Drug Targets, Volume 7 - Number 11

Editorial [Hot Topic: GSK-3 in Health and Disease (Guest Editor: H. Eldar-Finkelman)]

, 7(11): 1375

Hagit Eldar-Finkelman


DOI: 10.2174/1389450110607011375




Glycogen Synthase Kinase-3 - An Overview of An Over-Achieving Protein Kinase

, 7(11): 1377 - 1388

Lisa Kockeritz, Bradley Doble, Satish Patel and James R. Woodgett


DOI: 10.2174/1389450110607011377




Multiple Roles for Glycogen Synthase Kinase-3 as a Drug Target in Alzheimers Disease

, 7(11): 1389 - 1397

Hui-Chuan Huang and Peter S. Klein


DOI: 10.2174/1389450110607011389




Targeting Glycogen Synthase Kinase-3 in the CNS: Implications for the Development of New Treatments for Mood Disorders

, 7(11): 1399 - 1409

Todd D. Gould, Alyssa M. Picchini, Haim Einat and Husseini K. Manji


DOI: 10.2174/1389450110607011399




GSK3 at the Edge: Regulation of Developmental Specification and Cell Polarization

, 7(11): 1411 - 1419

Leung Kim and Alan R. Kimmel


DOI: 10.2174/1389450110607011411




Glycogen Synthase Kinase-3 (GSK3) in Psychiatric Diseases and Therapeutic Interventions

, 7(11): 1421 - 1434

Richard S. Jope and Myoung-Sun Roh


DOI: 10.2174/1389450110607011421




Role of Glycogen Synthase Kinase-3 in Insulin Resistance and Type 2 Diabetes

, 7(11): 1435 - 1441

Erik J. Henriksen and Betsy B. Dokken


DOI: 10.2174/1389450110607011435




Protein Kinase Inhibition: Different Approaches to Selective Inhibitor Design

, 7(11): 1443 - 1454

Giovanna Scapin


DOI: 10.2174/1389450110607011443




The Saccharomyces cerevisiae GSK-3β Homologs

, 7(11): 1455 - 1465

Yona Kassir, Ifat Rubin-Bejerano and Yael Mandel- Gutfreund


DOI: 10.2174/1389450110607011455




Editorial [Hot Topic: Ageing (Guest Editors: H.-P. Deigner and R. Kinscherf)]

, 7(11): 1467 - 1468

Hans-Peter Deigner and Ralf Kinscherf


DOI: 10.2174/1389450110607011467




Foreseeable Pharmaceutical Repair of Age-Related Extracellular Damage

, 7(11): 1469 - 1477

Aubrey D. N.J. de Grey


DOI: 10.2174/1389450110607011469




The Pharmacology of Ageing in Drosophila

, 7(11): 1479 - 1483

Mahtab Jafari, Anthony D. Long, Laurence D. Mueller and Michael R. Rose


DOI: 10.2174/1389450110607011479




Premature Ageing Prevention: Limitations and Perspectives of Pharmacological Interventions

, 7(11): 1485 - 1503

Vladimir N. Anisimov


DOI: 10.2174/1389450110607011485




The Deficit in Low Molecular Weight Thiols as a Target for Antiageing Therapy

, 7(11): 1505 - 1512

Wulf Droge, Ralf Kinscherf, Wulf Hildebrandt and Thomas Schmitt


DOI: 10.2174/1389450110607011505




Therapeutic Efficacy of Selegiline in Neurodegenerative Disorders and Neurological Diseases

, 7(11): 1513 - 1529

Manuchair Ebadi, Holly Brown-Borg, Jun Ren, Sushil Sharma, Shaik Shavali, Hesham El ReFaey and Edward C. Carlson


DOI: 10.2174/1389450110607011513




Towards a Life Prolonging Pill? Small Molecules with Anti-Ageing Properties

, 7(11): 1531 - 1537

Manuchair Wagner


DOI: 10.2174/1389450110607011531




The Endocannabinoid System in Ageing: A New Target for Drug Development

, 7(11): 1539 - 1552

A. Paradisi, S. Oddi and Maccarrone


DOI: 10.2174/1389450110607011539




The Role of NAD+ Dependent Histone Deacetylases (sirtuins) in Ageing

, 7(11): 1553 - 1560

Johannes Trapp


DOI: 10.2174/1389450110607011553




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