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Contents

Current Drug Targets, Volume 20 - Number 1

Review Article

Pro-inflammatory Cytokines: Cellular and Molecular Drug Targets for Glucocorticoid-induced-osteoporosis via Osteocyte

, 20(1): 1 - 15

Tiantian Wang, Xijie Yu* and Chengqi He*


DOI: 10.2174/1389450119666180405094046



Review Article

Melatonin as Potential Targets for Delaying Ovarian Aging

, 20(1): 16 - 28

Yanzhou Yang*, Hoi-Hung Cheung, Cheng Zhang, Ji Wu and Wai-Yee Chan


DOI: 10.2174/1389450119666180828144843



Review Article

Lipid-based Nanocarriers for siRNA Delivery: Challenges, Strategies and the Lessons Learned from the DODAX: MO Liposomal System

, 20(1): 29 - 50

Ana C.N. Oliveira, Joana Fernandes, Anabela Gonçalves, Andreia C. Gomes* and M.E.C.D. Real Oliveira*


DOI: 10.2174/1389450119666180703145410



Review Article

Toll-Like Receptor 4 and Heat-Shock Protein 70: Is it a New Target Pathway for Diabetic Vasculopathies?

, 20(1): 51 - 59

Amanda Almeida de Oliveira, R. Clinton Webb and Kenia Pedrosa Nunes*


DOI: 10.2174/1389450119666180821105544




Review Article

DNA Related Enzymes as Molecular Targets for Antiviral and Antitumoral Chemotherapy. A Natural Overview of the Current Perspectives

, 20(1): 70 - 80

Hugo A. Garro* and Carlos R. Pungitore


DOI: 10.2174/1389450119666180426103558



Review Article

The Value of Biomarkers in Optimizing the Use of Immuno-oncologic Therapy

, 20(1): 81 - 86

Carlos G. Ferreira, Andrea Nicolini*, Liliana Dalurzo, Stephen Stefani, Vanessa Teich and Natasha Leighl


DOI: 10.2174/1389450119666180911093143



Review Article

Exosomes in Therapy: Engineering, Pharmacokinetics and Future Applications

, 20(1): 87 - 95

Claudia Arenaccio, Chiara Chiozzini, Flavia Ferrantelli, Patrizia Leone, Eleonora Olivetta and Maurizio Federico*


DOI: 10.2174/1389450119666180521100409



Review Article


Review Article

Acid-Sensing Ion Channels Structural Aspects, Pathophysiological Importance and Experimental Mutational Data Available Across Various Species to Target Human ASIC1

, 20(1): 111 - 121

Anurag Singh Chauhan, Ganesh Chandra Sahoo*, Manas Ranjan Dikhit and Pradeep Das*


DOI: 10.2174/1389450119666180820103316



Review Article

Advances in Discovery of PDE10A Inhibitors for CNS-Related Disorders. Part 1: Overview of the Chemical and Biological Research

, 20(1): 122 - 143

Agnieszka Jankowska, Artur Świerczek, Elżbieta Wyska, Alicja Gawalska, Adam Bucki, Maciej Pawłowski and Grażyna Chłoń-Rzepa*


DOI: 10.2174/1389450119666180808105056




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