Contents

Current Drug Targets, Volume 18 - Number 4


Editorial


Review Article

Cellular and Molecular Networks in Chronic Myeloid Leukemia: The Leukemic Stem, Progenitor and Stromal Cell Interplay

, 18(4): 377 - 388

Danilo Perrotti, Giovannino Silvestri, Lorenzo Stramucci, Justine Yu and Rossana Trotta


DOI: 10.2174/1389450117666160615074120



Review Article

Unleashing the Guardian: The Targetable BCR-ABL/HAUSP/PML/PTEN Network in Chronic Myeloid Leukemia

, 18(4): 389 - 395

Alessandro Morotti, Davide Torti, Giovanna Carra, Cristina Panuzzo, Sabrina Crivellaro, Riccardo Taulli, Carmen Fava, Angelo Guerrasio and Giuseppe Saglio


DOI: 10.2174/1389450117666160608120527



Review Article

Is Going for Cure in CML Targeting Aberrant Glycogen Synthase Kinase 3β?

, 18(4): 396 - 404

Concetta Saponaro, Michele Maffia, Nicola Di Renzo and Addolorata Maria Luce Coluccia


DOI: 10.2174/1389450117666160817151723



Review Article

Stem Cell Guardians – Old and New Perspectives in LSC Biology

, 18(4): 405 - 413

Gillian A. Horne, Lorna Jackson, Vignir Helgason and Tessa L. Holyoake


DOI: 10.2174/1389450117666160712092944




Review Article

Specific Targeting of Akt Kinase Isoforms: Taking the Precise Path for Prevention and Treatment of Cancer

, 18(4): 421 - 435

Nand Kishor Roy, Devivasha Bordoloi, Javadi Monisha, Ganesan Padmavathi, Jibon Kotoky, Ramesh Golla and Ajaikumar B. Kunnumakkara


DOI: 10.2174/1389450117666160307145236



Review Article

Characterization and Management of Cutaneous Side Effects Related to the Immunosuppressive Treatment in Solid Organ Recipients

, 18(4): 436 - 446

Paola Savoia, Andrea Ranghino and Paolo Fava


DOI: 10.2174/1389450117666160112115524



Review Article


Review Article

ROCK in CNS: Different Roles of Isoforms and Therapeutic Target for Neurodegenerative Disorders

, 18(4): 455 - 462

Cheong-Meng Chong, Nana Ai and Simon Ming-Yuen Lee


DOI: 10.2174/1389450117666160401123825



Review Article


Review Article

Sirtuins: Possible Clinical Implications in Cardio and Cerebrovascular Diseases

, 18(4): 473 - 484

Valeria Conti, Maurizio Forte, Graziamaria Corbi, Giusy Russomanno, Luigi Formisano, Alessandro Landolfi, Viviana Izzo, Amelia Filippelli, Carmine Vecchione and Albino Carrizzo


DOI: 10.2174/1389450116666151019095903



The Role of Gender-specific Cytokine Pathways as Drug Targets and Gender- specific Biomarkers in Personalized Cancer Therapy

, 18(4): 485 - 495

Anna Maria Berghella, Ida Contasta, Roberto Lattanzio, Giancarlo Di Gregorio, Irma Campitelli, Marino Silvino, Luigi Liborio Liberatore, Luca Navarra, Giampaolo Caterino, Antonio Mongelli, Vincenzo Vittorini, Matteo Basta, Mauro Domenicucci, Nunzia Antonucci, Tiziana Del Beato, Enzo Secinaro, Fabiana Ciccone and Patrizia Pellegrini


DOI: 10.2174/1389450117666160630173647




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