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Contents

Current Drug Targets, Volume 18 - Number 12

Editorial   Open Access


Review Article

Aligning Animal Models of Clinical Germinal Matrix Hemorrhage, From Basic Correlation to Therapeutic Approach

, 18(12): 1316 - 1328

Tim Lekic, Damon Klebe, Pilar Pichon, Katarina Brankov, Sally Sultan, Devin McBride, Darlene Casel, Alhamza Al-Bayati, Yan Ding, Jiping Tang and John H. Zhang*


DOI: 10.2174/1389450117666160615100538



Review Article

Hematoma Expansion Following Intracerebral Hemorrhage: Mechanisms Targeting the Coagulation Cascade and Platelet Activation

, 18(12): 1329 - 1344

Sherrefa R. Burchell, Jiping Tang and John H. Zhang*


DOI: 10.2174/1389450118666170329152305



Review Article


Review Article   Open Access

Maintaining Plasma Fibrinogen Levels and Fibrinogen Replacement Therapies for Treatment of Intracranial Hemorrhage

, 18(12): 1349 - 1357

Devin McBride, Jiping Tang and John H. Zhang*


DOI: 10.2174/1389450117666151209123857



Review Article

A Therapeutic Target of Cerebral Hemorrhagic Stroke: Matrix Metalloproteinase- 9

, 18(12): 1358 - 1366

Baoqi Dang, Xiaochun Duan, Zhong Wang, Weichun He* and Gang Chen*


DOI: 10.2174/1389450118666170427151657



Review Article


Review Article

The Double Roles of the Prostaglandin E2 EP2 Receptor in Intracerebral Hemorrhage

, 18(12): 1377 - 1385

Xu Luo, Qiquan Zhu, Jie Zhang, Qin Huang, Zongyi Xie* and Yuan Cheng


DOI: 10.2174/1389450117666151209122826



Review Article

The Role of Pericytes in Neurovascular Unit: Emphasis on Stroke

, 18(12): 1386 - 1391

Ozgur Oztop-Cakmak, Ihsan Solaroglu and Yasemin Gursoy-Ozdemir*


DOI: 10.2174/1389450117666160613104523



Review Article

Neuroprotective Effects of Drug-Induced Therapeutic Hypothermia in Central Nervous System Diseases

, 18(12): 1392 - 1398

Junwei Ma, Yibin Wang, Zhong Wang, Haiying Li, Zhimin Wang* and Gang Chen*


DOI: 10.2174/1389450118666170607104251



Review Article

Intraventricular Recombinant Tissue Plasminogen Activator in Treatment of Aneurysmal Intraventricular Hemorrhage: A Meta-Analysis

, 18(12): 1399 - 1407

LiGen Shi, Liang Xu, LuFeng Shi, Dixon Brandon, Sheng Chen* and JianMin Zhang


DOI: 10.2174/1389450116666150907110815



Review Article

Neuroinflammation is Associated with Brain Extracellular TAU-Protein Release After Spontaneous Subarachnoid Hemorrhage

, 18(12): 1408 - 1416

Alois Josef Schiefecker*, Anelia Dietmann, Ronny Beer, Bettina Pfausler, Peter Lackner, Mario Kofler, Marlene Fischer, Gregor Broessner, Florian Sohm, Miriam Mulino, Claudius Thomé, Christian Humpel, Erich Schmutzhard and Raimund Helbok


DOI: 10.2174/1389450117666160201111804



Review Article

Nosocomial Infections and Antimicrobial Treatment in Coiled Patients with Aneurysmal Subarachnoid Hemorrhage

, 18(12): 1417 - 1423

Peter Lackner*, Christoph Mueller, Ronny Beer, Gregor Broessner, Marlene Fischer, Raimund Helbok, Alois Schiefecker, Erich Schmutzhard and Bettina Pfausler


DOI: 10.2174/1389450117666160401124426



Review Article

Early Brain Injury or Vasospasm? An Overview of Common Mechanisms

, 18(12): 1424 - 1429

Basak Topkoru, Emrah Egemen, Ihsan Solaroglu* and John H. Zhang


DOI: 10.2174/1389450117666160905112923



Review Article

Targeted Temperature Management in Spontaneous Intracerebral Hemorrhage: A Systematic Review

, 18(12): 1430 - 1440

Marlene Fischer, Alois Schiefecker, Peter Lackner, Florian Frank, Raimund Helbok, Ronny Beer, Bettina Pfausler, Erich Schmutzhard and Gregor Broessner*


DOI: 10.2174/1389450117666160703161511



Review Article

Pharmacological Management Options to Prevent and Reduce Ischemic Hemorrhagic Transformation

, 18(12): 1441 - 1459

Wing Mann Ho, Cesar Reis, Onat Akyol, Gokce Yilmaz Akyol, Richard Applegate II, Gary Stier, Robert Martin and John H. Zhang*


DOI: 10.2174/1389450117666160818115850



Review Article

Targeting Transient Receptor Potential Canonical Channels for Diseases of the Nervous System

, 18(12): 1460 - 1465

Yibin Wang, Jiyuan Bu, Haitao Shen, Haiying Li, Zhong Wang* and Gang Chen


DOI: 10.2174/1389450117666151209120007




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