Contents

Current Drug Targets, Volume 18 - Number 12

Editorial

Editorial:Brain Hemorrhages and Future Management

, 18(12): 1315

Gang Chen, Peter Lackner, Ihsan Solaroğlu and John H. Zhang


DOI: 10.2174/138945011812170824125820




Review Article

Aligning Animal Models of Clinical Germinal Matrix Hemorrhage, From Basic Correlation to Therapeutic Approach

, 18(12): 1316 - 1328

Tim Lekic, Damon Klebe, Pilar Pichon, Katarina Brankov, Sally Sultan, Devin McBride, Darlene Casel, Alhamza Al-Bayati, Yan Ding, Jiping Tang and John H. Zhang


DOI: 10.2174/1389450117666160615100538





Review Article

Hematoma Expansion Following Intracerebral Hemorrhage: Mechanisms Targeting the Coagulation Cascade and Platelet Activation

, 18(12): 1329 - 1344

Sherrefa R. Burchell, Jiping Tang and John H. Zhang


DOI: 10.2174/1389450118666170329152305





Review Article

Early Hematoma Enlargement in Primary Intracerebral Hemorrhage

, 18(12): 1345 - 1348

Du Cao, Qi Li, Peichun Fu, John Zhang and Jun Yang


DOI: 10.2174/1389450118666170427151011





Review Article

Maintaining Plasma Fibrinogen Levels and Fibrinogen Replacement Therapies for Treatment of Intracranial Hemorrhage

, 18(12): 1349 - 1357

Devin McBride, Jiping Tang and John H. Zhang


DOI: 10.2174/1389450117666151209123857





Review Article

A Therapeutic Target of Cerebral Hemorrhagic Stroke: Matrix Metalloproteinase- 9

, 18(12): 1358 - 1366

Baoqi Dang, Xiaochun Duan, Zhong Wang, Weichun He and Gang Chen


DOI: 10.2174/1389450118666170427151657





Review Article

Hematoma Expansion: Clinical and Molecular Predictors and Corresponding Pharmacological Treatment

, 18(12): 1367 - 1376

Gaiqing Wang and John Zhang


DOI: 10.2174/1389450117666160712092224





Review Article

The Double Roles of the Prostaglandin E2 EP2 Receptor in Intracerebral Hemorrhage

, 18(12): 1377 - 1385

Xu Luo, Qiquan Zhu, Jie Zhang, Qin Huang, Zongyi Xie and Yuan Cheng


DOI: 10.2174/1389450117666151209122826





Review Article

The Role of Pericytes in Neurovascular Unit: Emphasis on Stroke

, 18(12): 1386 - 1391

Ozgur Oztop-Cakmak, Ihsan Solaroglu and Yasemin Gursoy-Ozdemir


DOI: 10.2174/1389450117666160613104523





Review Article

Neuroprotective Effects of Drug-Induced Therapeutic Hypothermia in Central Nervous System Diseases

, 18(12): 1392 - 1398

Junwei Ma, Yibin Wang, Zhong Wang, Haiying Li, Zhimin Wang and Gang Chen


DOI: 10.2174/1389450118666170607104251





Review Article

Intraventricular Recombinant Tissue Plasminogen Activator in Treatment of Aneurysmal Intraventricular Hemorrhage: A Meta-Analysis

, 18(12): 1399 - 1407

LiGen Shi, Liang Xu, LuFeng Shi, Dixon Brandon, Sheng Chen and JianMin Zhang


DOI: 10.2174/1389450116666150907110815





Review Article

Neuroinflammation is Associated with Brain Extracellular TAU-Protein Release After Spontaneous Subarachnoid Hemorrhage

, 18(12): 1408 - 1416

Alois Josef Schiefecker, Anelia Dietmann, Ronny Beer, Bettina Pfausler, Peter Lackner, Mario Kofler, Marlene Fischer, Gregor Broessner, Florian Sohm, Miriam Mulino, Claudius Thomé, Christian Humpel, Erich Schmutzhard and Raimund Helbok


DOI: 10.2174/1389450117666160201111804





Review Article

Nosocomial Infections and Antimicrobial Treatment in Coiled Patients with Aneurysmal Subarachnoid Hemorrhage

, 18(12): 1417 - 1423

Peter Lackner, Christoph Mueller, Ronny Beer, Gregor Broessner, Marlene Fischer, Raimund Helbok, Alois Schiefecker, Erich Schmutzhard and Bettina Pfausler


DOI: 10.2174/1389450117666160401124426





Review Article

Early Brain Injury or Vasospasm? An Overview of Common Mechanisms

, 18(12): 1424 - 1429

Basak Topkoru, Emrah Egemen, Ihsan Solaroglu and John H. Zhang


DOI: 10.2174/1389450117666160905112923





Review Article

Targeted Temperature Management in Spontaneous Intracerebral Hemorrhage: A Systematic Review

, 18(12): 1430 - 1440

Marlene Fischer, Alois Schiefecker, Peter Lackner, Florian Frank, Raimund Helbok, Ronny Beer, Bettina Pfausler, Erich Schmutzhard and Gregor Broessner


DOI: 10.2174/1389450117666160703161511





Review Article

Pharmacological Management Options to Prevent and Reduce Ischemic Hemorrhagic Transformation

, 18(12): 1441 - 1459

Wing Mann Ho, Cesar Reis, Onat Akyol, Gokce Yilmaz Akyol, Richard Applegate II, Gary Stier, Robert Martin and John H. Zhang


DOI: 10.2174/1389450117666160818115850





Review Article

Targeting Transient Receptor Potential Canonical Channels for Diseases of the Nervous System

, 18(12): 1460 - 1465

Yibin Wang, Jiyuan Bu, Haitao Shen, Haiying Li, Zhong Wang and Gang Chen


DOI: 10.2174/1389450117666151209120007





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