Contents

Current Drug Targets, Volume 17 - Number 4

Meet Our Editorial Board Member:

, 17(4): 375

Stefania Vetrano


DOI: 10.2174/138945011704160212092714




Editorial

Editorial (Thematic Issue: Therapeutic Modulators of Cellular Senescence: Common Targets in Cancer And Aging)

, 17(4): 376

Mauro Provinciali and Marco Malavolta


DOI: 10.2174/138945011704160212093659




Morphological and Functional Characteristic of Senescent Cancer Cells

, 17(4): 377 - 387

Ewa Sikora, Grazyna Mosieniak and Malgorzata Alicja Sliwinska


DOI: 10.2174/1389450116666151019094724





Endothelial Cell Senescence and Inflammaging: MicroRNAs as Biomarkers and Innovative Therapeutic Tools

, 17(4): 388 - 397

Francesco Prattichizzo, Massimiliano Bonafè, Artan Ceka, Angelica Giuliani, Maria Rita Rippo, Massimo Re, Roberto Antonicelli, Antonio Domenico Procopio and Fabiola Olivieri


DOI: 10.2174/1389450116666150804105659





Stress Hormone-Mediated DNA Damage Response -- Implications for Cellular Senescence and Tumour Progression

, 17(4): 398 - 404

María Moreno-Villanueva and Alexander Bürkle


DOI: 10.2174/1389450116666151001113720





Roles of Apoptosis and Cellular Senescence in Cancer and Aging

, 17(4): 405 - 415

Claudia Cerella, Cindy Grandjenette, Mario Dicato and Marc Diederich


DOI: 10.2174/1389450116666150202155915





Endogenous Retroelements in Cellular Senescence and Related Pathogenic Processes: Promising Drug Targets in Age-Related Diseases

, 17(4): 416 - 427

Maurizio Cardelli, Robertina Giacconi, Marco Malavolta and Mauro Provinciali


DOI: 10.2174/1389450116666150518095829





The Impact of the Emerging Genomics Data on the Management of Agerelated Phenotypes in the Context of Cellular Senescence

, 17(4): 428 - 438

Alberto Montesanto, Silvana Geracitano, Sabrina Garasto, Sergio Fusco, Fabrizia Lattanzio, Giuseppe Passarino and Andrea Corsonello


DOI: 10.2174/1389450116666150120103329





Metformin for Prevention and Treatment of Colon Cancer: A Reappraisal of Experimental and Clinical Data

, 17(4): 439 - 446

Vladimir N. Anisimov


DOI: 10.2174/1389450116666150309113305





Pleiotropic Effects of Tocotrienols and Quercetin on Cellular Senescence: Introducing the Perspective of Senolytic Effects of Phytochemicals

, 17(4): 447 - 459

Marco Malavolta, Elisa Pierpaoli, Robertina Giacconi, Laura Costarelli, Francesco Piacenza, Andrea Basso, Maurizio Cardelli and Mauro Provinciali


DOI: 10.2174/1389450116666150907105104





Is Senescence Reversible?

, 17(4): 460 - 466

Shweta Chakradeo, Lynne W. Elmore and David A. Gewirtz


DOI: 10.2174/1389450116666150825113500





Targeted Drug Delivery for Cardiovascular and Cerebrovascular Diseases

, 17(4): 467 - 474

Jingjing Luan and Guangxi Zhai


DOI: 10.2174/1389450116666150416120224





The Key Role of Canonical Wnt/β-catenin Signaling in Cartilage Chondrocytes

, 17(4): 475 - 484

Xiaoliang Yuan, Haiqing Liu, Hao Huang, Hai Liu, Linfu Li, Jianqiong Yang, Weimei Shi, Weiyou Liu and Longhuo Wu


DOI: 10.2174/1389450116666150825112623





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