Contents

Current Drug Targets, Volume 15 - Number 14

Editorial

Editorial: New Strategies and Applications for Drugs Targeting EGFR and c-Met

, 15(14): 1261 - 1262

E. Giovannetti and L.G. Leon


DOI: 10.2174/1389450115666141107104844




Clinical Pharmacology of EGFR/Met Inhibitors in Non-Small Cell Lung Cancer

, 15(14): 1263 - 1272

Shigehiro Yagishita and Akinobu Hamada


DOI: 10.2174/1389450115666141110154838




Epidermal Growth Factor Receptor Targeting in Non-Small Cell Lung Cancer: Revisiting Different Strategies Against the Same Target

, 15(14): 1273 - 1283

Eduardo Castanon, Patricia Martin, Christian Rolfo, Juan P. Fusco, Lucia Ceniceros, Jairo Legaspi, Marta Santisteban and Ignacio Gil-Bazo


DOI: 10.2174/138945011514141216092935




The Role of cMet in Non-Small Cell Lung Cancer Resistant to EGFRInhibitors: Did We Really Find the Target?

, 15(14): 1284 - 1292

Francesco Passiglia, Nele Van Der Steen, Luis Raez, Patrick Pauwels, Ignacio Gil-Bazo, Edgardo Santos, Daniele Santini, Giovanni Tesoriere, Antonio Russo, Giuseppe Bronte, Karen Zwaenepoel, Federico Cappuzzo and Christian Rolfo


DOI: 10.2174/138945011514141216092739




EGFR as a Potential Target for the Treatment of Pancreatic Cancer: Dilemma and Controversies

, 15(14): 1293 - 1301

Reza Nedaeinia, Amir Avan, Mostafa Manian, Rasoul Salehi and Majid Ghayour-Mobarhan


DOI: 10.2174/1389450115666141125123003




Targeting c-MET/HGF Signaling Pathway in Upper Gastrointestinal Cancers: Rationale and Progress

, 15(14): 1302 - 1311

Sharareh Gholamin, Hamid Fiuji, Mina Maftouh, Reza Mirhafez, Fatemeh Homaei Shandiz and Amir Avan


DOI: 10.2174/1389450115666141107105456




Modulation of Signaling Enhances the Efficacy of the Combination of Satraplatin and Erlotinib

, 15(14): 1312 - 1321

Abolfazl Avan, Auke D. Adema, Eveline K. Hoebe, Charlotte M. Huijts, Amir Avan, Gareth J. Veal, Rob Ruijtenbeek, Katja Wosikowski and Godefridus J. Peters


DOI: 10.2174/1389450115666141107110321




The EGFR Pathway Regulates BCRP Expression in NSCLC Cells: Role of Erlotinib

, 15(14): 1322 - 1330

Letizia Porcelli, Elisa Giovannetti, Yehuda G. Assaraf, Gerrit Jansen, George L. Scheffer, Ietje Kathman, Amalia Azzariti, Angelo Paradiso and Godefridus J. Peters


DOI: 10.2174/1389450116666141205145620




Synergistic Activity of the c-Met and Tubulin Inhibitor Tivantinib (ARQ197) with Pemetrexed in Mesothelioma Cells

, 15(14): 1331 - 1340

Leticia G. Leon, Maria Gemelli, Rocco Sciarrillo, Amir Avan, Niccola Funel and Elisa Giovannetti


DOI: 10.2174/1389450116666141205160924




The Role of STAT3 Signaling in Mediating Tumor Resistance to Cancer Therapy

, 15(14): 1341 - 1353

Fiona H. Tan, Tracy L. Putoczki, Stanley S. Stylli and Rodney B. Luwor


DOI: 10.2174/1389450115666141120104146




Acknowledgements to Reviewers:

, 15(14): 1354 - 1355


DOI: 10.2174/138945011514141216100200




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