Contents

Current Drug Targets, Volume 15 - Number 1

Editorial (Thematic Issue:Targeting Loss of Tumor Suppressors for Cancer Therapeutics)

, 15(1): 1

Jenifer R. Prosperi and Kathleen Heppner Goss


DOI: 10.2174/138945011501140115104533




Targeting Tumor Suppressor Networks for Cancer Therapeutics

, 15(1): 2 - 16

Xuning Emily Guo, Bryan Ngo, Aram Sandaldjian Modrek and Wen-Hwa Lee


DOI: 10.2174/1389450114666140106095151




Targeting the BRCA1/2 Tumor Suppressors

, 15(1): 17 - 31

Eliot M. Rosen and Michael J. Pishvaian


DOI: 10.2174/1389450114666140106095432




Targeting the LKB1 Tumor Suppressor

, 15(1): 32 - 52

Rui-Xun Zhao and Zhi-Xiang Xu


DOI: 10.2174/1389450114666140106095811




Translating Mismatch Repair Mechanism into Cancer Care

, 15(1): 53 - 64

Christopher D. Heinen


DOI: 10.2174/1389450114666140106100128




Therapeutic Targeting of Cancers with Loss of PTEN Function

, 15(1): 65 - 79

Lloye M. Dillon and Todd W. Miller


DOI: 10.2174/1389450114666140106100909




Targeting Tumor Suppressor p53 for Cancer Therapy: Strategies, Challenges and Opportunities

, 15(1): 80 - 89

Bo Hong, A. Pieter J. van den Heuvel, Varun V. Prabhu, Shengliang Zhang and Wafik S. El-Deiry


DOI: 10.2174/1389450114666140106101412




Exploiting APC Function as a Novel Cancer Therapy

, 15(1): 90 - 102

Alyssa C. Lesko, Kathleen H. Goss and Jenifer R. Prosperi


DOI: 10.2174/1389450114666131108155418




The RNA-Dependent-RNA Polymerase, an Emerging Antiviral Drug Target for the Hendra Virus

, 15(1): 103 - 113

Tony Velkov, Vincenzo Carbone, Jesmin Akter, Sivashangarie Sivanesan, Jian Li, Travis Beddoe and Glenn A. Marsh


DOI: 10.2174/1389450114888131204163210




MDM2-p53 Interaction in Paediatric Solid Tumours: Preclinical Rationale, Biomarkers and Resistance

, 15(1): 114 - 123

Giuseppe Barone, Deborah A. Tweddle, Jason M. Shohet, Louis Chesler, Lucas Moreno, Andrew DJ Pearson and Tom Van Maerken


DOI: 10.2174/13894501113149990194




Oxycodone/Naloxone in the Management of Patients with Pain and Opioid–Induced Bowel Dysfunction

, 15(1): 124 - 135

Wojciech Leppert


DOI: 10.2174/13894501113149990210




Genomic Identification of Potential Targets Unique to Candida albicans for the Discovery of Antifungal Agents

, 15(1): 136 - 149

Himanshu Tripathi, Suaib Luqman, Abha Meena and Feroz Khan


DOI: 10.2174/138945011501140115112242




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