Contents

Current Drug Targets, Volume 14 - Number 4

Editorial (Hot Topic: Androgen Receptor and Prostate Cancer: New Insights in an Old Target Translate into Novel Therapeutic Strategies)

, 14(4): 399 - 400

Hannelore V. Heemers


DOI: 10.2174/1389450111314040001




Androgen Receptor: Past, Present and Future

, 14(4): 401 - 407

Lucy J. Schmidt and Donald J. Tindall


DOI: 10.2174/1389450111314040002




Improved Therapeutic Targeting of the Androgen Receptor: Rational Drug Design Improves Survival in Castration-Resistant Prostate Cancer

, 14(4): 408 - 419

Ai Chiin Lim and Gerhardt Attard


DOI: 10.2174/1389450111314040003




The Role of Intracrine Androgen Metabolism, Androgen Receptor and Apoptosis in the Survival and Recurrence of Prostate Cancer During Androgen Deprivation Therapy

, 14(4): 420 - 440

Michael V. Fiandalo, Wenjie Wu and James L. Mohler


DOI: 10.2174/1389450111314040004




Androgen Receptor Gene Rearrangements: New Perspectives on Prostate Cancer Progression

, 14(4): 441 - 449

Lucas J. Brand and Scott M. Dehm


DOI: 10.2174/1389450111314040005




Recurrent Rearrangements in Prostate Cancer: Causes and Therapeutic Potential

, 14(4): 450 - 459

Nicole M. White, Felix Y. Feng and Christopher A. Maher


DOI: 10.2174/1389450111314040006




The Role of Tumor Suppressor Dysregulation in Prostate Cancer Progression

, 14(4): 460 - 471

Jeffry L. Dean and Karen E. Knudsen


DOI: 10.2174/1389450111314040007




Genome-Wide Integrated Analyses of Androgen Receptor Signaling in Prostate Cancer Based on High-Throughput Technology

, 14(4): 472 - 480

Kuniko Horie-Inoue and Satoshi Inoue


DOI: 10.2174/1389450111314040008




Identification of a RhoA- and SRF-Dependent Mechanism of Androgen Action that is Associated with Prostate Cancer Progression

, 14(4): 481 - 489

Hannelore V. Heemers


DOI: 10.2174/1389450111314040009




Targeting Adenosine Signaling to Treatment of Diabetic Nephropathy

, 14(4): 490 - 496

Claudia Quezada, Sebastian Alarcon, Catherinne Jaramillo, Daniel Munoz, Carlos Oyarzun and Rody San Martin


DOI: 10.2174/1389450111314040010




Evolving Therapeutic Targets in Ischemic Stroke: A Concise Review

, 14(4): 497 - 506

Sinoy Sugunan, Diya Binoy Joseph and G. K. Rajanikant


DOI: 10.2174/1389450111314040011




Targeted D4 Dopamine Receptors: Implications for Drug Discovery and Therapeutic Development

, 14(4): 507 - 512

Radek Ptacek, Hana Kuzelova, George B. Stefano, Jiri Raboch and Richard M. Kream


DOI: 10.2174/1389450111314040012




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