Contents

Current Drug Targets, Volume 12 - Number 6

Editorial [Hot Topic: Mitochondria as a Drug Target in Health and Disease (Guest Editor: Paulo J. Oliveira)]

, 12(6): 761

Paulo J. Oliveira


DOI: 10.2174/138945011795528912




Techniques to Investigate Neuronal Mitochondrial Function and its Pharmacological Modulation

, 12(6): 762 - 773

Jorge M.A. Oliveira


DOI: 10.2174/138945011795528895




Investigating Mitochondrial Dysfunction to Increase Drug Safety in the Pharmaceutical Industry

, 12(6): 774 - 782

Sashi Nadanaciva and Yvonne Will


DOI: 10.2174/138945011795528985




Mild Mitochondrial Uncoupling as a Therapeutic Strategy

, 12(6): 783 - 789

Fernanda M. Cunha, Camille C. Caldeira da Silva, Fernanda M. Cerqueira and Alicia J. Kowaltowski


DOI: 10.2174/138945011795528778




Mitophagy in Neurodegeneration: An Opportunity for Therapy?

, 12(6): 790 - 799

R. X. Santos, S. C. Correia, C. Carvalho, S. Cardoso, M. S. Santos and P. I. Moreira


DOI: 10.2174/138945011795528813




Mitochondrial-Targeted Plastoquinone Derivatives. Effect on Senescence and Acute Age-Related Pathologies

, 12(6): 800 - 826

M. V. Skulachev, Y. N. Antonenko, V. N. Anisimov, B. V. Chernyak, D. A. Cherepanov, V. A. Chistyakov, M. V. Egorov, N. G. Kolosova, G. A. Korshunova, K. G. Lyamzaev, E. Y. Plotnikov, V. A. Roginsky, A. Y. Savchenko, I. I. Severina, F. F. Severin, T. P. Shkurat, V. N. Tashlitsky, K. M. Shidlovsky, M. Y. Vyssokikh, A. A. Zamyatnin, D. B. Zorov and V. P. Skulachev


DOI: 10.2174/138945011795528859




Mitochondrial Tolerance to Drugs and Toxic Agents in Ageing and Disease

, 12(6): 827 - 849

Jan Suski, Magdalena Lebiedzinska, Nuno G. Machado, Paulo J. Oliveira, Paolo Pinton, Jerzy Duszynski and Mariusz R. Wieckowski


DOI: 10.2174/138945011795529029




Berberine as a Promising Safe Anti-Cancer Agent- Is there a Role for Mitochondria?

, 12(6): 850 - 859

Catia V. Diogo, Nuno G. Machado, Ines A. Barbosa, Teresa L. Serafim, Ana Burgeiro and Paulo J. Oliveira


DOI: 10.2174/138945011795528930




Mitochondria as a Target for Exercise-Induced Cardioprotection

, 12(6): 860 - 871

Antonio Ascensao, Jose Lumini-Oliveira, Paulo J. Oliveira and Jose Magalhaes


DOI: 10.2174/138945011795529001




Regulation of Mitochondrial Biogenesis in Metabolic Syndrome

, 12(6): 872 - 878

Anabela P. Rolo, Ana P. Gomes and Carlos M. Palmeira


DOI: 10.2174/138945011795529056




Mitochondria in Chronic Liver Disease

, 12(6): 879 - 893

Ignazio Grattagliano, Stefan Russmann, Catia Diogo, Leonilde Bonfrate, Paulo J. Oliveira, David Q.-H. Wang and Piero Portincasa


DOI: 10.2174/138945011795528877




The Adenine Nucleotide Translocase 2, a Mitochondrial Target for Anticancer Biotherapy

, 12(6): 894 - 901

Ossama Sharaf el dein, Eleonore Mayola, Joel Chopineau and Catherine Brenner


DOI: 10.2174/138945011795529047




Repressing the Activity of Protein Kinase CK2 Releases Mitochondria-Mediated Apoptosis in Cancer Cells

, 12(6): 902 - 908

Ismail Muhamad Hanif and Shazib Pervaiz


DOI: 10.2174/138945011795528831




The NK-1 Receptor: A New Target in Cancer Therapy

, 12(6): 909 - 921

Miguel Munoz, Marisa Rosso and Rafael Covenas


DOI: 10.2174/138945011795528796




Mechanisms of Acquired Resistance to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors and New Therapeutic Perspectives in Non Small Cell Lung Cancer

, 12(6): 922 - 933

Laura Bonanno, Antonio Jirillo and Adolfo Favaretto


DOI: 10.2174/138945011795528958




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