Contents

Current Drug Targets, Volume 12 - Number 5

Editorial [Hot Topic: ABC Transporters: Role in Modulation of Drug Pharmacokinetics and in Physiopathology and Therapeutic Perspectives (Guest Editor: Francoise Van Bambeke)]

, 12(5): 598 - 599

Francoise Van Bambeke


DOI: 10.2174/138945011795378531




ABC Multidrug Transporters: Target for Modulation of Drug Pharmacokinetics and Drug-Drug Interactions

, 12(5): 600 - 620

Beatrice Marquez and Francoise Van Bambeke


DOI: 10.2174/138945011795378504




Improving Cancer Chemotherapy with Modulators of ABC Drug Transporters

, 12(5): 621 - 630

S. Shukla, S. Ohnuma and S. V. Ambudkar


DOI: 10.2174/138945011795378540




Genetic Polymorphisms of ATP-Binding Cassette Transporters ABCB1 and ABCC2 and their Impact on Drug Disposition

, 12(5): 631 - 646

Vincent Haufroid


DOI: 10.2174/138945011795378487




ATP-Binding Cassette Transporters A1 and G1, HDL Metabolism, Cholesterol Efflux, and Inflammation: Important Targets for the Treatment of Atherosclerosis

, 12(5): 647 - 660

Dan Ye, Bart Lammers, Ying Zhao, Illiana Meurs, Theo J.C. Van Berkel and Miranda Van Eck


DOI: 10.2174/138945011795378522




The Canalicular Bile Salt Export Pump BSEP (ABCB11) as a Potential Therapeutic Target

, 12(5): 661 - 670

Bruno Stieger and Ulrich Beuers


DOI: 10.2174/138945011795378496




ABCC6 as a Target in Pseudoxanthoma Elasticum

, 12(5): 671 - 682

Andras Varadi, Zalan Szabo, Viola Pomozi, Hugues de Boussac, Krisztina Fulop and Tamas Aranyi


DOI: 10.2174/138945011795378612




Targeting CFTR: How to Treat Cystic Fibrosis by CFTR-Repairing Therapies

, 12(5): 683 - 693

Margarida D. Amaral


DOI: 10.2174/138945011795378586




ABC Subfamily D Proteins and Very Long Chain Fatty Acid Metabolism as Novel Targets in Adrenoleukodystrophy

, 12(5): 694 - 706

Masashi Morita, Nobuyuki Shimozawa, Yoshinori Kashiwayama, Yasuyuki Suzuki and Tsuneo Imanaka


DOI: 10.2174/138945011795378577




Editorial [Hot Topic: Calcium Regulatory Proteins as Therapeutic Targets (Guest Editor: Livia C. Hool)]

, 12(5): 707 - 708

Livia C. Hool


DOI: 10.2174/138945011795378513




The Ryanodine Receptor: A Pivotal Ca2+ Regulatory Protein and Potential Therapeutic Drug Target

, 12(5): 709 - 723

Angela F. Dulhunty, Marco G. Casarotto and Nicole A. Beard


DOI: 10.2174/138945011795378595




Properties and Therapeutic Potential of Transient Receptor Potential Channels with Putative Roles in Adversity: Focus on TRPC5, TRPM2 and TRPA1

, 12(5): 724 - 736

L. H. Jiang, N. Gamper and D. J. Beech


DOI: 10.2174/138945011795378568




Triple Threat: The Na+/Ca2+ Exchanger in the Pathophysiology of Cardiac Arrhythmia, Ischemia and Heart Failure

, 12(5): 737 - 747

Christian Pott, Lars Eckardt and Joshua I. Goldhaber


DOI: 10.2174/138945011795378559




Targeting Calcium and the Mitochondria in Prevention of Pathology in the Heart

, 12(5): 748 - 760

Helena M. Viola and Livia C. Hool


DOI: 10.2174/138945011795378603




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