Contents

Current Drug Targets, Volume 12 - Number 14

Editorial [Hot Topic: Targeted Therapies in Oncology (Guest Editor: Monica M. Mita)]

, 12(14): 1998 - 2000

Francis J. Giles


DOI: 10.2174/138945011798829375




Heat Shock Proteins: A Potential Anticancer Target

, 12(14): 2001 - 2008

Kamalesh K. Sankhala, Monica M. Mita, Alain C. Mita and Chris H. Takimoto


DOI: 10.2174/138945011798829339




Vascular Disrupting Agents (VDA) in Oncology: Advancing Towards New Therapeutic Paradigms in the Clinic

, 12(14): 2009 - 2015

Matthew A. Spear, Patricia LoRusso, Alain Mita and Monica Mita


DOI: 10.2174/138945011798829366




Blockade of Insulin-Like Growth Factor Type-1 Receptor with Cixutumumab (IMC-A12): A Novel Approach to Treatment for Multiple Cancers

, 12(14): 2016 - 2033

Eric K. Rowinsky, Jonathan D. Schwartz, Naseem Zojwalla, Hagop Youssoufian, Floyd Fox, Philippe Pultar, Ruslan Novosyadlyy, Jan Cosaert and Dale L. Ludwig


DOI: 10.2174/138945011798829401




The Emerging Role of Poly(ADP-Ribose) Polymerase Inhibitors in Cancer Treatment

, 12(14): 2034 - 2044

Shahneen K. Sandhu, Timothy A. Yap and Johann S. de Bono


DOI: 10.2174/138945011798829438




HGF/c-MET Targeted Therapeutics: Novel Strategies for Cancer Medicine

, 12(14): 2045 - 2058

Timothy A. Yap, Shahneen K. Sandhu, Salma M. Alam and Johann S. de Bono


DOI: 10.2174/138945011798829348




The Pim Kinases: New Targets for Drug Development

, 12(14): 2059 - 2066

Ronan Swords, Kevin Kelly, Jennifer Carew, Stefan Nawrocki, Devalingam Mahalingam, John Sarantopoulos, David Bearss and Francis Giles


DOI: 10.2174/138945011798829447




Targeting Aurora Kinases in Cancer Treatment

, 12(14): 2067 - 2078

Kevin R. Kelly, Jeffrey Ecsedy, Devalingam Mahalingam, Steffan T. Nawrocki, Swaminathan Padmanabhan, Francis J. Giles and Jennifer S. Carew


DOI: 10.2174/138945011798829410




Targeting Trail Towards the Clinic

, 12(14): 2079 - 2090

Devalingam Mahalingam, Corina N.A.M. Oldenhuis, Eva Szegezdi, Francis J. Giles, Elisabeth G.E. de Vries, Steven de Jong and Steffan T. Nawrocki


DOI: 10.2174/138945011798829357




The Hedgehog Knows Many Tricks

, 12(14): 2091 - 2095

Glen J. Weiss, Alain C. Mita and Daniel D. Von Hoff


DOI: 10.2174/138945011798829429




Role of Advanced Glycation End Products (AGEs) in Osteoporosis in Diabetes

, 12(14): 2096 - 2102

Sho-ichi Yamagishi


DOI: 10.2174/138945011798829456




Molecular Players at the Intersection of Obesity and Osteoarthritis

, 12(14): 2103 - 2128

M. Luisa Bonet, Nuria Granados and Andreu Palou


DOI: 10.2174/138945011798829393




Novel Targets for Malaria Therapy

, 12(14): 2129 - 2143

Priyanka Prabhu and Vandana Patravale


DOI: 10.2174/138945011798829384




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